Thymoproteasome: Role in Thymic Selection and Clinical Significance as a Diagnostic Marker for Thymic Epithelial Tumors

The proteasome: molecular machinery and pathophysiological roles

(2012) Keiji Tanaka et al.   BIOLOGICAL CHEMISTRY

β5t-containing thymoproteasome: specific expression in thymic cortical epithelial cells and role in positive selection of CD8+ T cells

(2012) Yousuke Takahama et al.   CURRENT OPINION IN IMMUNOLOGY

Proteasome subunit β5t expression in cervical ectopic thymoma

(2012) Utano Tomaru et al.   JOURNAL OF CLINICAL PATHOLOGY

Decreased Proteasomal Activity Causes Age-Related Phenotypes and Promotes the Development of Metabolic Abnormalities

(2011) Utano Tomaru et al.   AMERICAN JOURNAL OF PATHOLOGY

Expression of Proteasome Subunit β5t in Thymic Epithelial Tumors

(2011) Yosuke Yamada et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Thymoma and autoimmunity

(2011) Shahar Shelly et al.   Cellular & Molecular Immunology

Ontogeny of thymic cortical epithelial cells expressing the thymoproteasome subunit β5t

(2011) Adiratna Mat Ripen et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Comparative genomic analysis of the proteasome β5t subunit gene: implications for the origin and evolution of thymoproteasomes

(2011) Yoichi Sutoh et al.   IMMUNOGENETICS

Thymoma and paraneoplastic myasthenia gravis

(2010) A. Marx et al.   AUTOIMMUNITY

Activity-Based Profiling Reveals Reactivity of the Murine Thymoproteasome-Specific Subunit β5t

(2010) Bogdan I. Florea et al.   CHEMISTRY & BIOLOGY

Why CD8+ T Cells Need Diversity When Growing Up

(2010) Kristin A. Hogquist et al.   IMMUNITY

Thymoproteasome Shapes Immunocompetent Repertoire of CD8+ T Cells

(2010) Takeshi Nitta et al.   IMMUNITY

Biphasic Aire expression in early embryos and in medullary thymic epithelial cells before end-stage terminal differentiation

(2010) Yumiko Nishikawa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Role of thymic cortex-specific self-peptides in positive selection of T cells

(2010) Yousuke Takahama et al.   SEMINARS IN IMMUNOLOGY

Exclusive expression of proteasome subunit  5t in the human thymic cortex

(2009) U. Tomaru et al.   BLOOD

The adaptive phenotype of cortical thymic epithelial cells

(2009) Thomas Boehm   EUROPEAN JOURNAL OF IMMUNOLOGY

Immunohistochemical differential diagnosis between thymic carcinoma and type B3 thymoma: diagnostic utility of hypoxic marker, GLUT-1, in thymic epithelial neoplasms

(2009) Masakazu Kojika et al.   MODERN PATHOLOGY

Origin and evolution of the adaptive immune system: genetic events and selective pressures

(2009) Martin F. Flajnik et al.   NATURE REVIEWS GENETICS

The proteasome: Overview of structure and functions

(2009) Keiji TANAKA   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

A Single Peptide-MHC Complex Positively Selects a Diverse and Specific CD8 T Cell Repertoire

(2009) B. Wang et al.   SCIENCE

Two Types of Antigen Receptor Systems in Vertebrates

(2009) Masanori Kasahara et al.   ZOOLOGICAL SCIENCE

Thymoproteasome: probable role in generating positively selecting peptides

(2008) Shigeo Murata et al.   CURRENT OPINION IN IMMUNOLOGY

Genetic Evidence Linking Age-Dependent Attenuation of the 26S Proteasome with the Aging Process

(2008) A. Tonoki et al.   MOLECULAR AND CELLULAR BIOLOGY

Modest cortex and promiscuous medulla for thymic repertoire formation

(2008) Yousuke Takahama et al.   TRENDS IN IMMUNOLOGY