Inhibition of Proteasome Activity Induces Formation of Alternative Proteasome Complexes

Mammalian proteasome subtypes: Their diversity in structure and function

(2016) Burkhardt Dahlmann   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Regulation of 26S Proteasome Activity in Pulmonary Fibrosis

(2015) Nora Semren et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Evolution of Proteasome Regulators in Eukaryotes

(2015) Philippe Fort et al.   Genome Biology and Evolution

Deciphering preferential interactions within supramolecular protein complexes: the proteasome case

(2015) B. Fabre et al.   Molecular Systems Biology

Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling

(2015) Natura Myeku et al.   NATURE MEDICINE

cAMP-induced phosphorylation of 26S proteasomes on Rpn6/PSMD11 enhances their activity and the degradation of misfolded proteins

(2015) Sudarsanareddy Lokireddy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Immunoproteasome Function in the Lung

(2015) Ilona E. Keller et al.   Scientific Reports

Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits

(2015) Diego Acosta-Alvear et al.   eLife

Regulation of the Proteasome: Evaluating the Lung Proteasome as a New Therapeutic Target

(2014) Silke Meiners et al.   ANTIOXIDANTS & REDOX SIGNALING

Proteasome-Mediated Processing of Nrf1 Is Essential for Coordinate Induction of All Proteasome Subunits and p97

(2014) Zhe Sha et al.   CURRENT BIOLOGY

Molecular and Cellular Roles of PI31 (PSMF1) Protein in Regulation of Proteasome Function

(2014) Xiaohua Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Label-Free Quantitative Proteomics Reveals the Dynamics of Proteasome Complexes Composition and Stoichiometry in a Wide Range of Human Cell Lines

(2014) Bertrand Fabre et al.   JOURNAL OF PROTEOME RESEARCH

Differential global structural changes in the core particle of yeast and mouse proteasome induced by ligand binding

(2014) Marcelino Arciniega et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reversible 26S Proteasome Disassembly upon Mitochondrial Stress

(2014) Nurit Livnat-Levanon et al.   Cell Reports

Structural Biology of the Proteasome

(2013) Erik Kish-Trier et al.   Annual Review of Biophysics

Regulation of proteasome activity in health and disease

(2013) Marion Schmidt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Acetylation-Mediated Proteasomal Degradation of Core Histones during DNA Repair and Spermatogenesis

(2013) Min-Xian Qian et al.   CELL

The REGγ Proteasome Regulates Hepatic Lipid Metabolism through Inhibition of Autophagy

(2013) Shuxian Dong et al.   Cell Metabolism

U.S. Food and Drug Administration Approval: Carfilzomib for the Treatment of Multiple Myeloma

(2013) T. M. Herndon et al.   CLINICAL CANCER RESEARCH

Acute cigarette smoke exposure impairs proteasome function in the lung

(2012) Sabine H. van Rijt et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The Proteasome Activator PA200 Regulates Tumor Cell Responsiveness to Glutamine and Resistance to Ionizing Radiation

(2012) J. Blickwedehl et al.   MOLECULAR CANCER RESEARCH

Increased proteasome activity in human embryonic stem cells is regulated by PSMD11

(2012) David Vilchez et al.   NATURE

Proteasome allostery as a population shift between interchanging conformers

(2012) A. M. Ruschak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteasome Activator 200: The HEAT is on…

(2011) Anca F. Savulescu et al.   MOLECULAR & CELLULAR PROTEOMICS

Proteasome Activators

(2011) Beth M. Stadtmueller et al.   MOLECULAR CELL

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Building on bortezomib: second-generation proteasome inhibitors as anti-cancer therapy

(2010) Lawrence R. Dick et al.   DRUG DISCOVERY TODAY

REGγ modulates p53 activity by regulating its cellular localization

(2010) Jian Liu et al.   JOURNAL OF CELL SCIENCE

Transcription Factor Nrf1 Mediates the Proteasome Recovery Pathway after Proteasome Inhibition in Mammalian Cells

(2010) Senthil K. Radhakrishnan et al.   MOLECULAR CELL

Proteasomal Degradation Is Transcriptionally Controlled by TCF11 via an ERAD-Dependent Feedback Loop

(2010) Janos Steffen et al.   MOLECULAR CELL

Comparative Analysis of REGγ Expression in Mouse and Human Tissues

(2010) Guowu Yu et al.   Journal of Molecular Cell Biology

Recognition and Processing of Ubiquitin-Protein Conjugates by the Proteasome

(2009) Daniel Finley   Annual Review of Biochemistry

A Tetrahedral Transition State at the Active Sites of the 20S Proteasome Is Coupled to Opening of the α-Ring Channel

(2009) Pawel A. Osmulski et al.   STRUCTURE

Proteasome activator PA28γ regulates p53 by enhancing its MDM2-mediated degradation

(2008) Zhuo Zhang et al.   EMBO JOURNAL

Genetic Evidence Linking Age-Dependent Attenuation of the 26S Proteasome with the Aging Process

(2008) A. Tonoki et al.   MOLECULAR AND CELLULAR BIOLOGY

A Novel Role for PA28γ-Proteasome in Nuclear Speckle Organization and SR Protein Trafficking

(2008) Véronique Baldin et al.   MOLECULAR BIOLOGY OF THE CELL

Role for proteasome activator PA200 and postglutamyl proteasome activity in genomic stability

(2008) J. Blickwedehl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High yield bacterial expression and purification of active recombinant PA28αβ complex

(2008) Aurélie Y. Le Feuvre et al.   PROTEIN EXPRESSION AND PURIFICATION