A Putative Role for the Immunoproteasome in the Maintenance of Pluripotency in Human Embryonic Stem Cells

ERK1 and ERK2 regulate embryonic stem cell self-renewal through phosphorylation of Klf4

(2012) Myoung Ok Kim et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Derivation and Functional Analysis of Patient-Specific Induced Pluripotent Stem Cells as an In Vitro Model of Chronic Granulomatous Disease

(2012) Yan Jiang et al.   STEM CELLS

An Important Role for CDK2 in G1 to S Checkpoint Activation and DNA Damage Response in Human Embryonic Stem Cells

(2011) Irina Neganova et al.   STEM CELLS

Proteasome inhibitors in cancer therapy

(2011) Lisa J. Crawford et al.   Journal of Cell Communication and Signaling

The immunoproteasome, the 20S proteasome and the PA28αβ proteasome regulator are oxidative-stress-adaptive proteolytic complexes

(2010) Andrew M. Pickering et al.   BIOCHEMICAL JOURNAL

G1to S transition and pluripotency: Two sides of the same coin?

(2010) Majlinda Lako et al.   CELL CYCLE

Regulation of the 26S Proteasome Complex During Oxidative Stress

(2010) X. Wang et al.   Science Signaling

Human Induced Pluripotent Stem Cell Lines Show Stress Defense Mechanisms and Mitochondrial Regulation Similar to Those of Human Embryonic Stem Cells

(2010) Lyle Armstrong et al.   STEM CELLS

A gene expression signature shared by human mature oocytes and embryonic stem cells

(2009) Said Assou et al.   BMC GENOMICS

WWP2 promotes degradation of transcription factor OCT4 in human embryonic stem cells

(2009) Huiming Xu et al.   CELL RESEARCH

A role for NANOG in G1 to S transition in human embryonic stem cells through direct binding of CDK6 and CDC25A

(2009) Xin Zhang et al.   JOURNAL OF CELL BIOLOGY

Human embryonic stem cells are pre-mitotically committed to self-renewal and acquire a lengthened G1 phase upon lineage programming

(2009) Klaus A. Becker et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Targeting proteins for degradation

(2009) Erin K Schrader et al.   Nature Chemical Biology

A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis

(2009) Tony Muchamuel et al.   NATURE MEDICINE

Regulation of proteasome-mediated protein degradation during oxidative stress and aging

(2008) Nicolle Breusing et al.   BIOLOGICAL CHEMISTRY

Activation of p53 by nutlin leads to rapid differentiation of human embryonic stem cells

(2008) T Maimets et al.   ONCOGENE

Expression and functional analysis of G1 to S regulatory components reveals an important role for CDK2 in cell cycle regulation in human embryonic stem cells

(2008) I Neganova et al.   ONCOGENE

Downregulation of Multiple Stress Defense Mechanisms During Differentiation of Human Embryonic Stem Cells

(2007) Gabriele Saretzki et al.   STEM CELLS