The complement system, toll-like receptors and inflammasomes in host defense: three musketeers’ one target

Complement and the Regulation of T Cell Responses

(2018) Erin E. West et al.   Annual Review of Immunology

IRF8 Regulates Transcription of Naip s for NLRC4 Inflammasome Activation

(2018) Rajendra Karki et al.   CELL

Complement C3 Drives Autophagy-Dependent Restriction of Cyto-invasive Bacteria

(2018) Matthew T. Sorbara et al.   Cell Host & Microbe

Bacterial Autophagy: How to Take a Complement

(2018) Vanessa Sancho-Shimizu et al.   Cell Host & Microbe

Recent advances in inflammasome biology

(2018) David E Place et al.   CURRENT OPINION IN IMMUNOLOGY

Toll-like receptors in immunity and inflammatory diseases: Past, present, and future

(2018) Kumar Vijay   INTERNATIONAL IMMUNOPHARMACOLOGY

Emerging Insights into Noncanonical Inflammasome Recognition of Microbes

(2018) Ashley J. Russo et al.   JOURNAL OF MOLECULAR BIOLOGY

Bacteria restricted via C3-mediated autophagy

(2018) Seth Thomas Scanlon   SCIENCE

C1q restrains autoimmunity and viral infection by regulating CD8+T cell metabolism

(2018) Guang Sheng Ling et al.   SCIENCE

Complement Component C1q: Historical Perspective of a Functionally Versatile, and Structurally Unusual, Serum Protein

(2018) Kenneth B. M. Reid   Frontiers in Immunology

Complement Receptor 3-Mediated Inhibition of Inflammasome Priming by Ras GTPase-Activating Protein During Francisella tularensis Phagocytosis by Human Mononuclear Phagocytes

(2018) Ky V. Hoang et al.   Frontiers in Immunology

Complement Component C3 Is Highly Expressed in Human Pancreatic Islets and Prevents β Cell Death via ATG16L1 Interaction and Autophagy Regulation

(2018) Ben C. King et al.   Cell Metabolism

The role of CR3 (CD11b/CD18) and CR4 (CD11c/CD18) in complement-mediated phagocytosis and podosome formation by human phagocytes

(2017) Szilvia Lukácsi et al.   IMMUNOLOGY LETTERS

TLRs/NLRs: Shaping the landscape of host immunity

(2017) Komal Dolasia et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Autophagy downstream of endosomal Toll-like receptor signaling in macrophages is a key mechanism for resistance to Leishmania major infection

(2017) Luis H. Franco et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LC3-Associated Phagocytosis and Inflammation

(2017) Bradlee L. Heckmann et al.   JOURNAL OF MOLECULAR BIOLOGY

Alternative functions of the complement protein C1q at embryo implantation site

(2017) Chiara Agostinis et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

C1q as an autocrine and paracrine regulator of cellular functions

(2017) Berhane Ghebrehiwet et al.   MOLECULAR IMMUNOLOGY

Regulation of epithelial cell expressed C3 in the intestine – Relevance for the pathophysiology of inflammatory bowel disease?

(2017) Annika Sünderhauf et al.   MOLECULAR IMMUNOLOGY

Autophagy and inflammasomes

(2017) James Harris et al.   MOLECULAR IMMUNOLOGY

Inflammasome and Autophagy Regulation: A Two-way Street

(2017) Qian Sun et al.   MOLECULAR MEDICINE

Depletion of the Third Complement Component Ameliorates Age-Dependent Oxidative Stress and Positively Modulates Autophagic Activity in Aged Retinas in a Mouse Model

(2017) Dorota Rogińska et al.   Oxidative Medicine and Cellular Longevity

CD14 is critical for TLR2-mediated M1 macrophage activation triggered by N-glycan recognition

(2017) Thiago Aparecido da Silva et al.   Scientific Reports

HDAC6 controls innate immune and autophagy responses to TLR-mediated signalling by the intracellular bacteria Listeria monocytogenes

(2017) Olga Moreno-Gonzalo et al.   PLoS Pathogens

Toll-like receptors: promising therapeutic targets for inflammatory diseases

(2016) Asma Achek et al.   ARCHIVES OF PHARMACAL RESEARCH

Complement-Mediated Regulation of Metabolism and Basic Cellular Processes

(2016) Christoph Hess et al.   IMMUNITY

The “ins and outs” of complement-driven immune responses

(2016) Simon Freeley et al.   IMMUNOLOGICAL REVIEWS

Old dogs-new tricks: immunoregulatory properties of C3 and C5 cleavage fragments

(2016) Admar Verschoor et al.   IMMUNOLOGICAL REVIEWS

Evolution of the complement system: from defense of the single cell to guardian of the intravascular space

(2016) Michelle Elvington et al.   IMMUNOLOGICAL REVIEWS

More than complementing Tolls: complement-Toll-like receptor synergy and crosstalk in innate immunity and inflammation

(2016) George Hajishengallis et al.   IMMUNOLOGICAL REVIEWS

Complement component C3 - The “Swiss Army Knife” of innate immunity and host defense

(2016) Daniel Ricklin et al.   IMMUNOLOGICAL REVIEWS

Complement-mediated ‘bystander’ damage initiates host NLRP3 inflammasome activation

(2016) Rahul Suresh et al.   JOURNAL OF CELL SCIENCE

Role of CCL7 in Type I Hypersensitivity Reactions in Murine Experimental Allergic Conjunctivitis

(2016) Chuan-Hui Kuo et al.   JOURNAL OF IMMUNOLOGY

Reassessing the Evolutionary Importance of Inflammasomes

(2016) Vivien I. Maltez et al.   JOURNAL OF IMMUNOLOGY

TRIF-dependent TLR signaling, its functions in host defense and inflammation, and its potential as a therapeutic target

(2016) M. Obayed Ullah et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Activation of phagocytic activity in astrocytes by reduced expression of the inflammasome component ASC and its implication in a mouse model of Alzheimer disease

(2016) Julien Couturier et al.   Journal of Neuroinflammation

Complement in disease: a defence system turning offensive

(2016) Daniel Ricklin et al.   Nature Reviews Nephrology

Soluble Toll-Like Receptors 2 and 4 in Cerebrospinal Fluid of Patients with Acute Hydrocephalus following Aneurysmal Subarachnoid Haemorrhage

(2016) Bartosz Sokół et al.   PLoS One

T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4+ T cells

(2016) G. Arbore et al.   SCIENCE

Complement therapeutics

(2016) Daniel Ricklin et al.   SEMINARS IN IMMUNOLOGY

TLR2 Regulates Complement-Mediated Inflammation Induced by Blood Loss During Hemorrhage

(2016) Jeremy Goering et al.   SHOCK

Mechanism and Regulation of NLRP3 Inflammasome Activation

(2016) Yuan He et al.   TRENDS IN BIOCHEMICAL SCIENCES

T-bet is a key modulator of IL-23-driven pathogenic CD4+ T cell responses in the intestine

(2016) Thomas Krausgruber et al.   Nature Communications

Functional and Evolutionary Analyses Identify Proteolysis as a General Mechanism for NLRP1 Inflammasome Activation

(2016) Joseph Chavarría-Smith et al.   PLoS Pathogens

The Role of Complement in Cnidarian-Dinoflagellate Symbiosis and Immune Challenge in the Sea Anemone Aiptasia pallida

(2016) Angela Z. Poole et al.   Frontiers in Microbiology

Insights into Soluble Toll-Like Receptor 2 as a Downregulator of Virally Induced Inflammation

(2016) Bethany M. Henrick et al.   Frontiers in Immunology

Exposure of Human CD4 T Cells to IL-12 Results in Enhanced TCR-Induced Cytokine Production, Altered TCR Signaling, and Increased Oxidative Metabolism

(2016) Aldo Vacaflores et al.   PLoS One

Commensal Bacteria-Induced Inflammasome Activation in Mouse and Human Macrophages Is Dependent on Potassium Efflux but Does Not Require Phagocytosis or Bacterial Viability

(2016) Kejie Chen et al.   PLoS One

Mechanisms of Toll-like Receptor 4 Endocytosis Reveal a Common Immune-Evasion Strategy Used by Pathogenic and Commensal Bacteria

(2015) Yunhao Tan et al.   IMMUNITY

Fundamental role of C1q in autoimmunity and inflammation

(2015) Myoungsun Son et al.   IMMUNOLOGIC RESEARCH

Autophagy as a Stress Response Pathway in the Immune System

(2015) Abhisek Bhattacharya et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Pouring fuel on the fire: Th17 cells, the environment, and autoimmunity

(2015) Patrick R. Burkett et al.   JOURNAL OF CLINICAL INVESTIGATION

Autophagy and autophagy-related proteins in the immune system

(2015) Shusaku T Shibutani et al.   NATURE IMMUNOLOGY

CD14 dependence of TLR4 endocytosis and TRIF signaling displays ligand specificity and is dissociable in endotoxin tolerance

(2015) Rajesh Rajaiah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD14 and Complement Crosstalk and Largely Mediate the Transcriptional Response to Escherichia coli in Human Whole Blood as Revealed by DNA Microarray

(2015) Corinna Lau et al.   PLoS One

Chronic TLR Stimulation Controls NLRP3 Inflammasome Activation through IL-10 Mediated Regulation of NLRP3 Expression and Caspase-8 Activation

(2015) Prajwal Gurung et al.   Scientific Reports

Eating for good health: Linking autophagy and phagocytosis in host defense

(2014) Miguel A. Sanjuan et al.   Autophagy

LC3-associated phagocytosis

(2014) Susana Romao et al.   Autophagy

Chlamydia pneumoniae harness host NLRP3 inflammasome-mediated caspase-1 activation for optimal intracellular growth in murine macrophages

(2014) Ryota Itoh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The discriminative capacity of soluble Toll-like receptor (sTLR)2 and sTLR4 in inflammatory diseases

(2014) Jaap ten Oever et al.   BMC IMMUNOLOGY

Mechanisms and Functions of Inflammasomes

(2014) Mohamed Lamkanfi et al.   CELL

Noncanonical Inflammasome Activation of Caspase-4/Caspase-11 Mediates Epithelial Defenses against Enteric Bacterial Pathogens

(2014) Leigh A. Knodler et al.   Cell Host & Microbe

Interaction of Autophagy and Toll-Like Receptors: A Regulatory Cross- Talk - Even in Cancer Cells?

(2014) Gyorgyi Muzes et al.   CURRENT DRUG TARGETS

Complement C5a potentiates uric acid crystal-induced IL-1β production

(2014) Ling-Ling An et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-12 Produced by Dendritic Cells Augments CD8+ T Cell Activation through the Production of the Chemokines CCL1 and CCL17

(2014) C. J. Henry et al.   JOURNAL OF IMMUNOLOGY

Endothelial PINK1 Mediates the Protective Effects of NLRP3 Deficiency during Lethal Oxidant Injury

(2014) Y. Zhang et al.   JOURNAL OF IMMUNOLOGY

Cholesterol Crystals Induce Complement-Dependent Inflammasome Activation and Cytokine Release

(2014) E. O. Samstad et al.   JOURNAL OF IMMUNOLOGY

Dectin-1–Dependent LC3 Recruitment to Phagosomes Enhances Fungicidal Activity in Macrophages

(2014) Jenny M. Tam et al.   JOURNAL OF INFECTIOUS DISEASES

cC1qR/CR and gC1qR/p33: Observations in cancer

(2014) Ellinor I.B. Peerschke et al.   MOLECULAR IMMUNOLOGY

Activation of Toll-Like Receptors and Inflammasome Complexes in the Diabetic Cardiomyopathy-Associated Inflammation

(2014) J. Fuentes-Antrás et al.   International Journal of Endocrinology

Reactive oxygen species at the crossroads of inflammasome and inflammation

(2014) Anantha Harijith et al.   Frontiers in Physiology

Monocyte Expressed Macromolecular C1 and C1q Receptors as Molecular Sensors of Danger: Implications in SLE

(2014) Berhane Ghebrehiwet et al.   Frontiers in Immunology

Evolution of Innate Immunity: Clues from Invertebrates via Fish to Mammals

(2014) Kurt Buchmann   Frontiers in Immunology

Pattern Recognition Receptors and Autophagy

(2014) Ji Eun Oh et al.   Frontiers in Immunology

Is the scavenger receptor MARCO a new immune checkpoint?

(2014) Mohamed S Arredouani   OncoImmunology

C3a modulates IL-1  secretion in human monocytes by regulating ATP efflux and subsequent NLRP3 inflammasome activation

(2013) E. Asgari et al.   BLOOD

Insights into phagocytosis-coupled activation of pattern recognition receptors and inflammasomes

(2013) Julien Moretti et al.   CURRENT OPINION IN IMMUNOLOGY

 -glucan signaling connects phagocytosis to autophagy

(2013) J. Ma et al.   GLYCOBIOLOGY

Kinase AKT controls innate immune cell development and function

(2013) Yan Zhang et al.   IMMUNOLOGY

The complement membrane attack complex triggers intracellular Ca2+ fluxes leading to NLRP3 inflammasome activation

(2013) K. Triantafilou et al.   JOURNAL OF CELL SCIENCE

IL-12 and type I interferon prolong the division of activated CD8 T cells by maintaining high-affinity IL-2 signaling in vivo

(2013) Gabriel R. Starbeck-Miller et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: The NLRP3 Inflammasome Links Complement-Mediated Inflammation and IL-1  Release

(2013) F. Laudisi et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: TLR Signaling Licenses IRAK1 for Rapid Activation of the NLRP3 Inflammasome

(2013) T. Fernandes-Alnemri et al.   JOURNAL OF IMMUNOLOGY

TLR2 & Co: a critical analysis of the complex interactions between TLR2 and coreceptors

(2013) Jeroen van Bergenhenegouwen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function

(2013) Anna Sokolovska et al.   NATURE IMMUNOLOGY

S100A8 and S100A9 Induce Cytokine Expression and Regulate the NLRP3 Inflammasome via ROS-Dependent Activation of NF-κB1

(2013) Jean-Christophe Simard et al.   PLoS One

Cytokine Spatzle binds to the Drosophila immunoreceptor Toll with a neurotrophin-like specificity and couples receptor activation

(2013) M. Lewis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neutralizing Tumor-Promoting Chronic Inflammation: A Magic Bullet?

(2013) L. M. Coussens et al.   SCIENCE

Targeting the TLR Co-Receptor CD14 with TLR2-Derived Peptides Modulates Immune Responses to Pathogens

(2013) A.-C. Raby et al.   Science Translational Medicine

Lose the battle to win the war: bacterial strategies for evading host inflammasome activation

(2013) Naomi Higa et al.   TRENDS IN MICROBIOLOGY

Inflammasomes and Their Roles in Health and Disease

(2012) Mohamed Lamkanfi et al.   Annual Review of Cell and Developmental Biology

Autophagy and the Immune System

(2012) Petric Kuballa et al.   Annual Review of Immunology

Recognition of Bacteria by Inflammasomes

(2012) Jakob von Moltke et al.   Annual Review of Immunology

Virus Recognition by Toll-7 Activates Antiviral Autophagy in Drosophila

(2012) Margaret Nakamoto et al.   IMMUNITY

Noncanonical Autophagy Is Required for Type I Interferon Secretion in Response to DNA-Immune Complexes

(2012) Jill Henault et al.   IMMUNITY

Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis

(2012) Kenichi Shimada et al.   IMMUNITY

Evolution of inflammasome functions in vertebrates: Inflammasome and caspase-1 trigger fish macrophage cell death but are dispensable for the processing of IL-1β

(2012) Diego Angosto et al.   Innate Immunity

Dectin-1-triggered Recruitment of Light Chain 3 Protein to Phagosomes Facilitates Major Histocompatibility Complex Class II Presentation of Fungal-derived Antigens

(2012) Jun Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extensive evolutionary and functional diversity among mammalian AIM2-like receptors

(2012) Rebecca L. Brunette et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Complement Protein C1q Directs Macrophage Polarization and Limits Inflammasome Activity during the Uptake of Apoptotic Cells

(2012) M. E. Benoit et al.   JOURNAL OF IMMUNOLOGY

TLR Agonists Stimulate Nlrp3-Dependent IL-1  Production Independently of the Purinergic P2X7 Receptor in Dendritic Cells and In Vivo

(2012) Y. He et al.   JOURNAL OF IMMUNOLOGY

Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction

(2012) Chong-Shan Shi et al.   NATURE IMMUNOLOGY

Toll-like receptor (TLR) and inflammasome actions in the central nervous system

(2012) Richa Hanamsagar et al.   TRENDS IN IMMUNOLOGY

The Complement System at the Embryo Implantation Site: Friend or Foe?

(2012) R. Bulla et al.   Frontiers in Immunology

CD14 Controls the LPS-Induced Endocytosis of Toll-like Receptor 4

(2011) Ivan Zanoni et al.   CELL

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Human complement Factor H modulates C1q-mediated phagocytosis of apoptotic cells

(2011) Yu-Hoi Kang et al.   IMMUNOBIOLOGY

Functional modulation of human monocytes derived DCs by anaphylatoxins C3a and C5a

(2011) Ke Li et al.   IMMUNOBIOLOGY

NLRP4 Negatively Regulates Autophagic Processes through an Association with Beclin1

(2011) N. Jounai et al.   JOURNAL OF IMMUNOLOGY

Manipulation of autophagy by bacteria for their own benefit

(2011) Michinaga Ogawa et al.   MICROBIOLOGY AND IMMUNOLOGY

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

TLR2 Signaling Contributes to Rapid Inflammasome Activation during F. novicida Infection

(2011) Crystal L. Jones et al.   PLoS One

Staphylococcus aureus Evades Lysozyme-Based Peptidoglycan Digestion that Links Phagocytosis, Inflammasome Activation, and IL-1β Secretion

(2010) Takahiro Shimada et al.   Cell Host & Microbe

A Yersinia Effector Protein Promotes Virulence by Preventing Inflammasome Recognition of the Type III Secretion System

(2010) Igor E. Brodsky et al.   Cell Host & Microbe

The Classical and Regulatory Functions of C1q in Immunity and Autoimmunity

(2010) Jinhua Lu et al.   Cellular & Molecular Immunology

The roles of IL-12 and IL-23 in CD8+ T cell-mediated immunity against Listeria monocytogenes: Insights from a DC vaccination model

(2010) Curtis J. Henry et al.   CELLULAR IMMUNOLOGY

The genome of the sponge Amphimedon queenslandica provides new perspectives into the origin of Toll-like and interleukin 1 receptor pathways

(2010) Marie E. A. Gauthier et al.   EVOLUTION & DEVELOPMENT

Stimulation of the endosomal TLR pathway enhances autophagy-induced cell death in radiotherapy of breast cancer

(2010) Su-Jin Kang et al.   Genes & Genomics

Molecular Mechanism That Induces Activation of Spätzle, the Ligand for theDrosophilaToll Receptor

(2010) Christopher J. Arnot et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of the Transcription Factor CREB in Immune Function

(2010) A. Y. Wen et al.   JOURNAL OF IMMUNOLOGY

Complement regulates TLR4-mediated inflammatory responses during intestinal ischemia reperfusion

(2010) Michael R. Pope et al.   MOLECULAR IMMUNOLOGY

Complement control protein factor H: The good, the bad, and the inadequate

(2010) Viviana P. Ferreira et al.   MOLECULAR IMMUNOLOGY

Activation of autophagy during cell death requires the engulfment receptor Draper

(2010) Christina K. McPhee et al.   NATURE

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

(2010) Teresa Fernandes-Alnemri et al.   NATURE IMMUNOLOGY

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria

(2010) Edward A Miao et al.   NATURE IMMUNOLOGY

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis

(2010) J. W. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microbial Hijacking of Complement-Toll-Like Receptor Crosstalk

(2010) M. Wang et al.   Science Signaling

Crosstalk pathways between Toll-like receptors and the complement system

(2010) George Hajishengallis et al.   TRENDS IN IMMUNOLOGY

Properdin: Emerging Roles of a Pattern-Recognition Molecule

(2009) Claudia Kemper et al.   Annual Review of Immunology

Toll-like receptors in control of immunological autophagy

(2009) M A Delgado et al.   CELL DEATH AND DIFFERENTIATION

Soluble forms of Toll-like receptor 4 are present in human saliva and modulate tumour necrosis factor-α secretion by macrophage-like cells

(2009) S. L. Zunt et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Toll-Like Receptor Stimulation Enhances Phagocytosis and Intracellular Killing of Nonencapsulated and Encapsulated Streptococcus pneumoniae by Murine Microglia

(2009) S. Ribes et al.   INFECTION AND IMMUNITY

Caspases: evolutionary aspects of their functions in vertebrates

(2009) K. Sakamaki et al.   JOURNAL OF FISH BIOLOGY

Dendritic Cell Function in Allostimulation Is Modulated by C5aR Signaling

(2009) Q. Peng et al.   JOURNAL OF IMMUNOLOGY

Factor H and Factor H-Related Protein 1 Bind to Human Neutrophils via Complement Receptor 3, Mediate Attachment to Candida albicans, and Enhance Neutrophil Antimicrobial Activity

(2009) J. Losse et al.   JOURNAL OF IMMUNOLOGY

Complement Activation by CpG in a Human Whole Blood Loop System: Mechanisms and Immunomodulatory Effects

(2009) S. M. Mangsbo et al.   JOURNAL OF IMMUNOLOGY

C1q Differentially Modulates Phagocytosis and Cytokine Responses during Ingestion of Apoptotic Cells by Human Monocytes, Macrophages, and Dendritic Cells

(2009) D. A. Fraser et al.   JOURNAL OF IMMUNOLOGY

The role of the anaphylatoxins in health and disease

(2009) Andreas Klos et al.   MOLECULAR IMMUNOLOGY

Tumours with PI3K activation are resistant to dietary restriction

(2009) Nada Y. Kalaany et al.   NATURE

The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17–producing effector T helper cells in vivo

(2009) Mandy J McGeachy et al.   NATURE IMMUNOLOGY

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY

Human genetic deficiencies reveal the roles of complement in the inflammatory network: Lessons from nature

(2009) K. T. Lappegard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyclic AMP

(2008) Carlos H. Serezani et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

With a little help from my friends: modulation of phagocytosis through TLR activation

(2008) Erin Tricker et al.   CELL RESEARCH

MyD88-independent activation of a novel actin-Cdc42/Rac pathway is required for Toll-like receptor-stimulated phagocytosis

(2008) Ling Kong et al.   CELL RESEARCH

Toll-like receptors control autophagy

(2008) Mónica A Delgado et al.   EMBO JOURNAL

Locally Produced Complement Fragments C5a and C3a Provide Both Costimulatory and Survival Signals to Naive CD4+ T Cells

(2008) Michael G. Strainic et al.   IMMUNITY

Toll-like receptor signaling in the lysosomal pathways

(2008) Miguel A. Sanjuan et al.   IMMUNOLOGICAL REVIEWS

MyD88 and Trif Target Beclin 1 to Trigger Autophagy in Macrophages

(2008) Chong-Shan Shi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A role of macrophage complement receptor CRIg in immune clearance and inflammation

(2008) Jeannie Q. He et al.   MOLECULAR IMMUNOLOGY

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production

(2008) Tatsuya Saitoh et al.   NATURE

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE

A pervasive role of histone acetyltransferases and deacetylases in an NF-κB-signaling code

(2008) Miriam Calao et al.   TRENDS IN BIOCHEMICAL SCIENCES

Molecular and functional characterization of gilthead seabream Sparus aurata caspase-1: The first identification of an inflammatory caspase in fish

(2007) Gloria López-Castejón et al.   MOLECULAR IMMUNOLOGY