Complement: a key system for immune surveillance and homeostasis

IFN-γ and IL-17 Production in Experimental Autoimmune Encephalomyelitis Depends on Local APC–T Cell Complement Production

(2014) Jinbo Liu et al.   JOURNAL OF IMMUNOLOGY

Murine Low-Density Lipoprotein Receptor-Related Protein 1 (LRP) Is Required for Phagocytosis of Targets Bearing LRP Ligands but Is Not Required for C1q-Triggered Enhancement of Phagocytosis

(2014) A. P. Lillis et al.   JOURNAL OF IMMUNOLOGY

Complement, Age-Related Macular Degeneration and a Vision of the Future

(2010) Karen M. Gehrs   ARCHIVES OF OPHTHALMOLOGY

Synapse elimination during development and disease: immune molecules take centre stage

(2010) Dorothy P. Schafer et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Complement anaphylatoxin C5a contributes to hemodialysis-associated thrombosis

(2010) I. Kourtzelis et al.   BLOOD

Complement fragments C3a and C5a: The salt and pepper of the immune response

(2010) Steven H. Sacks   EUROPEAN JOURNAL OF IMMUNOLOGY

Fifth complement cascade protein (C5) cleavage fragments disrupt the SDF-1/CXCR4 axis: Further evidence that innate immunity orchestrates the mobilization of hematopoietic stem/progenitor cells

(2010) Ali Jalili et al.   EXPERIMENTAL HEMATOLOGY

A complex role for complement in allergic asthma

(2010) Xun Zhang et al.   Expert Review of Clinical Immunology

The C5a Receptor (C5aR) C5L2 Is a Modulator of C5aR-mediated Signal Transduction

(2010) Claire E. Bamberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Complement drives Th17 cell differentiation and triggers autoimmune arthritis

(2010) Motomu Hashimoto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Importance of Cytokines in Murine Allergic Airway Disease and Human Asthma

(2010) Fred D. Finkelman et al.   JOURNAL OF IMMUNOLOGY

Alternative Complement Pathway in Schizophrenia

(2010) Anna Boyajyan et al.   NEUROCHEMICAL RESEARCH

"Complementing" Toll Signaling

(2010) J. C. Kagan   Science Signaling

Microbial Hijacking of Complement-Toll-Like Receptor Crosstalk

(2010) M. Wang et al.   Science Signaling

Crosstalk pathways between Toll-like receptors and the complement system

(2010) George Hajishengallis et al.   TRENDS IN IMMUNOLOGY

Complement-Mediated Ischemia-Reperfusion Injury

(2009) Gwendolyn M. P. Diepenhorst et al.   ANNALS OF SURGERY

Clinical Significance of Complement Deficiencies

(2009) H. David Pettigrew et al.   Annals of the New York Academy of Sciences

Complement: coming full circle

(2009) Gaëlle Le Friec et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Complement promotes the development of inflammatory T-helper 17 cells through synergistic interaction with Toll-like receptor signaling and interleukin-6 production

(2009) C. Fang et al.   BLOOD

Complement and its role in innate and adaptive immune responses

(2009) Jason R Dunkelberger et al.   CELL RESEARCH

Complement classical pathway components are all important in clearance of apoptotic and secondary necrotic cells

(2009) B. Gullstrand et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The complement system in schizophrenia

(2009) K.R. Mayilyan et al.   DRUG NEWS & PERSPECTIVES

C5a receptor-deficient dendritic cells promote induction of Treg and Th17 cells

(2009) Donald J. Weaver et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Paths reunited: Initiation of the classical and lectin pathways of complement activation

(2009) Russell Wallis et al.   IMMUNOBIOLOGY

Dendritic Cell Function in Allostimulation Is Modulated by C5aR Signaling

(2009) Q. Peng et al.   JOURNAL OF IMMUNOLOGY

C3 Promotes Expansion of CD8+ and CD4+ T Cells in a Listeria monocytogenes Infection

(2009) Y. Nakayama et al.   JOURNAL OF IMMUNOLOGY

MASP-1, a Promiscuous Complement Protease: Structure of Its Catalytic Region Reveals the Basis of Its Broad Specificity

(2009) J. Dobo et al.   JOURNAL OF IMMUNOLOGY

Treatment with a C5aR Antagonist Decreases Pathology and Enhances Behavioral Performance in Murine Models of Alzheimer's Disease

(2009) M. I. Fonseca et al.   JOURNAL OF IMMUNOLOGY

A Protective Role for C5a in the Development of Allergic Asthma Associated with Altered Levels of B7-H1 and B7-DC on Plasmacytoid Dendritic Cells

(2009) X. Zhang et al.   JOURNAL OF IMMUNOLOGY

The Regulation of Liver Cell Survival by Complement

(2009) M. M. Markiewski et al.   JOURNAL OF IMMUNOLOGY

Functions of C5a receptors

(2009) Peter A. Ward   JOURNAL OF MOLECULAR MEDICINE-JMM

Single nucleotide polymorphisms of complement component 5 and periodontitis

(2009) L. Chai et al.   JOURNAL OF PERIODONTAL RESEARCH

Autoimmune forms of thrombotic micorangiopathy and membranoproliferative glomerulonephritis: Indications for a disease spectrum and common pathogenic principles

(2009) Christine Skerka et al.   MOLECULAR IMMUNOLOGY

Complement in human diseases: Lessons from complement deficiencies

(2009) Marina Botto et al.   MOLECULAR IMMUNOLOGY

The role of the anaphylatoxins in health and disease

(2009) Andreas Klos et al.   MOLECULAR IMMUNOLOGY

Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor

(2009) Suzan H M Rooijakkers et al.   NATURE IMMUNOLOGY

Structure of complement fragment C3b–factor H and implications for host protection by complement regulators

(2009) Jin Wu et al.   NATURE IMMUNOLOGY

Therapeutic potential of complement modulation

(2009) Eric Wagner et al.   NATURE REVIEWS DRUG DISCOVERY

Periodontitis in systemic rheumatic diseases

(2009) Paola de Pablo et al.   Nature Reviews Rheumatology

Atypical Hemolytic–Uremic Syndrome

(2009) Marina Noris et al.   NEW ENGLAND JOURNAL OF MEDICINE

Complementary Tolls in the periodontium: how periodontal bacteria modify complement and Toll-like receptor responses to prevail in the host

(2009) Jennifer L. Krauss et al.   PERIODONTOLOGY 2000

Human genetic deficiencies reveal the roles of complement in the inflammatory network: Lessons from nature

(2009) K. T. Lappegard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD14-Mac-1 interactions in Bacillus anthracis spore internalization by macrophages

(2009) C. Oliva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The pivotal role of the complement system in aging and age-related macular degeneration: Hypothesis re-visited

(2009) Don H. Anderson et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Taking Complement to the Clinic - has the Time Finally Come?

(2009) P. J. Lachmann et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Complement-Derived Anaphylatoxin C3a Regulates In Vitro Differentiation and Migration of Neural Progenitor Cells

(2009) Noriko Shinjyo et al.   STEM CELLS

Is complement good or bad for cancer patients? A new perspective on an old dilemma

(2009) Maciej M. Markiewski et al.   TRENDS IN IMMUNOLOGY

Can cells and biomaterials in therapeutic medicine be shielded from innate immune recognition?

(2009) Bo Nilsson et al.   TRENDS IN IMMUNOLOGY

Cyclic AMP plays a critical role in C3a-receptor-mediated regulation of dendritic cells in antigen uptake and T-cell stimulation

(2008) K. Li et al.   BLOOD

Complement in multiple sclerosis: its role in disease and potential as a biomarker

(2008) G. Ingram et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Locally Produced Complement Fragments C5a and C3a Provide Both Costimulatory and Survival Signals to Naive CD4+ T Cells

(2008) Michael G. Strainic et al.   IMMUNITY

The spectrum of complement alternative pathway-mediated diseases

(2008) V. Michael Holers   IMMUNOLOGICAL REVIEWS

Activation of Complement Component C5

(2008) Nenoo Rawal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Inflammatory Response to Cardiopulmonary Bypass: Part 1—Mechanisms of Pathogenesis

(2008) Oliver J. Warren et al.   JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA

Complexity of complement activation in sepsis

(2008) Maciej M. Markiewski et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The alternative complement pathway revisited

(2008) Morten Harboe et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Mannose-binding lectin enhances Toll-like receptors 2 and 6 signaling from the phagosome

(2008) W.K. Eddie Ip et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The complement cascade: Yin-Yang in neuroinflammation - neuro-protection and -degeneration

(2008) Jessy John Alexander et al.   JOURNAL OF NEUROCHEMISTRY

Increased IL-23 secretion and altered chemokine production by dendritic cells upon CD46 activation in patients with multiple sclerosis

(2008) Adi Vaknin-Dembinsky et al.   JOURNAL OF NEUROIMMUNOLOGY

A role of macrophage complement receptor CRIg in immune clearance and inflammation

(2008) Jeannie Q. He et al.   MOLECULAR IMMUNOLOGY

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE

Modulation of the antitumor immune response by complement

(2008) Maciej M Markiewski et al.   NATURE IMMUNOLOGY

Functional roles for C5a receptors in sepsis

(2008) Daniel Rittirsch et al.   NATURE MEDICINE

Complement evasion by human pathogens

(2008) John D. Lambris et al.   NATURE REVIEWS MICROBIOLOGY

Complement and humoral immunity

(2008) Michael C. Carroll   VACCINE

Discrimination between host and pathogens by the complement system

(2008) Michael K. Pangburn et al.   VACCINE

A Large-Scale Rheumatoid Arthritis Genetic Study Identifies Association at Chromosome 9q33.2

(2008) Monica Chang et al.   PLoS Genetics

Role of complement and complement regulators in the removal of apoptotic cells

(2007) L.A. Trouw et al.   MOLECULAR IMMUNOLOGY

The tick-over theory revisited: Formation and regulation of the soluble alternative complement C3 convertase (C3(H2O)Bb)

(2007) Fredrik Bexborn et al.   MOLECULAR IMMUNOLOGY