The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

Pathogen recognition in the innate immune response

(2009) Himanshu Kumar et al.   BIOCHEMICAL JOURNAL

International Gene Trap Project: Towards Gene-driven Saturation Mutagenesis in Mice

(2009) Masatake Araki et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Francisella tularensis Phagosomal Escape Does Not Require Acidification of the Phagosome

(2009) D. L. Clemens et al.   INFECTION AND IMMUNITY

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Pyrin Critical to Macrophage IL-1  Response to Francisella Challenge

(2009) M. A. Gavrilin et al.   JOURNAL OF IMMUNOLOGY

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

(2009) Teresa Fernandes-Alnemri et al.   NATURE

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

(2009) Veit Hornung et al.   NATURE

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

(2009) Tilmann Bürckstümmer et al.   NATURE IMMUNOLOGY

Life on the inside: the intracellular lifestyle of cytosolic bacteria

(2009) Katrina Ray et al.   NATURE REVIEWS MICROBIOLOGY

TLR–Dependent Control of Francisella tularensis Infection and Host Inflammatory Responses

(2009) Allison L. Abplanalp et al.   PLoS One

HIN-200 Proteins Regulate Caspase Activation in Response to Foreign Cytoplasmic DNA

(2009) T. L. Roberts et al.   SCIENCE

NLR-mediated control of inflammasome assembly in the host response against bacterial pathogens

(2009) Igor E. Brodsky et al.   SEMINARS IN IMMUNOLOGY

The NLR Gene Family: A Standard Nomenclature

(2008) Jenny P.-Y. Ting et al.   IMMUNITY

Acquisition of the Vacuolar ATPase Proton Pump and Phagosome Acidification Are Essential for Escape of Francisella tularensis into the Macrophage Cytosol

(2008) M. Santic et al.   INFECTION AND IMMUNITY

The Early Phagosomal Stage of Francisella tularensis Determines Optimal Phagosomal Escape and Francisella Pathogenicity Island Protein Expression

(2008) A. Chong et al.   INFECTION AND IMMUNITY

The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response

(2008) Daniel A. Muruve et al.   NATURE

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

(2008) Annett Halle et al.   NATURE IMMUNOLOGY

Phagocytosis-induced apoptosis of macrophages is linked to uptake, killing and degradation of bacteria

(2007) Tobias Frankenberg et al.   EUROPEAN JOURNAL OF IMMUNOLOGY