TLR2 Signaling Contributes to Rapid Inflammasome Activation during F. novicida Infection

Macrophage Proinflammatory Response to Francisella tularensis Live Vaccine Strain Requires Coordination of Multiple Signaling Pathways

(2014) L. E. Cole et al.   JOURNAL OF IMMUNOLOGY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Cutting Edge: Mutation of Francisella tularensis mviN Leads to Increased Macrophage Absent in Melanoma 2 Inflammasome Activation and a Loss of Virulence

(2010) T. K. Ulland et al.   JOURNAL OF IMMUNOLOGY

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

(2010) Vijay A K Rathinam et al.   NATURE IMMUNOLOGY

The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

(2010) Teresa Fernandes-Alnemri et al.   NATURE IMMUNOLOGY

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria

(2010) Edward A Miao et al.   NATURE IMMUNOLOGY

Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis

(2010) J. W. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Francisella tularensis Induces Extensive Caspase-3 Activation and Apoptotic Cell Death in the Tissues of Infected Mice

(2009) J. R. Wickstrum et al.   INFECTION AND IMMUNITY

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Phagosomal retention of Francisella tularensis results in TIRAP/Mal-independent TLR2 signaling

(2009) Leah E. Cole et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Regulation of apoptosis and anti-apoptosis signalling by Francisella tularensis

(2009) Marina Santic et al.   MICROBES AND INFECTION

The Francisella tularensis pathogenicity island encodes a secretion system that is required for phagosome escape and virulence

(2009) Jeffrey R. Barker et al.   MOLECULAR MICROBIOLOGY

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

(2009) Teresa Fernandes-Alnemri et al.   NATURE

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

(2009) Veit Hornung et al.   NATURE

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

(2009) Tilmann Bürckstümmer et al.   NATURE IMMUNOLOGY

TLR–Dependent Control of Francisella tularensis Infection and Host Inflammatory Responses

(2009) Allison L. Abplanalp et al.   PLoS One

IL-1, IL-18, and IL-33 families of cytokines

(2008) William P. Arend et al.   IMMUNOLOGICAL REVIEWS

Infected-Host-Cell Repertoire and Cellular Response in the Lung following Inhalation of Francisella tularensis Schu S4, LVS, or U112

(2008) J. D. Hall et al.   INFECTION AND IMMUNITY