Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function

Caspase-11 Promotes the Fusion of Phagosomes Harboring Pathogenic Bacteria with Lysosomes by Modulating Actin Polymerization

(2012) Anwari Akhter et al.   IMMUNITY

Phagosomal Degradation Increases TLR Access to Bacterial Ligands and Enhances Macrophage Sensitivity to Bacteria

(2011) A. J. Wolf et al.   JOURNAL OF IMMUNOLOGY

Inflammasome activation in NADPH oxidase defective mononuclear phagocytes from patients with chronic granulomatous disease

(2010) F. Meissner et al.   BLOOD

Staphylococcus aureus Evades Lysozyme-Based Peptidoglycan Digestion that Links Phagocytosis, Inflammasome Activation, and IL-1β Secretion

(2010) Takahiro Shimada et al.   Cell Host & Microbe

Inflammasome Inhibition as a Pathogenic Stealth Mechanism

(2010) Debra J. Taxman et al.   Cell Host & Microbe

Intracellular mechanisms of antigen cross presentation in dendritic cells

(2010) Sebastian Amigorena et al.   CURRENT OPINION IN IMMUNOLOGY

Phagocytosis and Phagosome Acidification Are Required for Pathogen Processing and MyD88-Dependent Responses to Staphylococcus aureus

(2010) W. K. E. Ip et al.   JOURNAL OF IMMUNOLOGY

TLR9 Is Actively Recruited to Aspergillus fumigatus Phagosomes and Requires the N-Terminal Proteolytic Cleavage Domain for Proper Intracellular Trafficking

(2010) P. V. Kasperkovitz et al.   JOURNAL OF IMMUNOLOGY

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

The Phagosomal Proteome in Interferon-γ-Activated Macrophages

(2009) Matthias Trost et al.   IMMUNITY

Direct recruitment of H+-ATPase from lysosomes for phagosomal acidification

(2009) G.-H. Sun-Wada et al.   JOURNAL OF CELL SCIENCE

Caspase-7 Activation by the Nlrc4/Ipaf Inflammasome Restricts Legionella pneumophila Infection

(2009) Anwari Akhter et al.   PLoS Pathogens

The Inflammasomes

(2009) Mohamed Lamkanfi et al.   PLoS Pathogens

NADPH oxidase controls phagosomal pH and antigen cross-presentation in human dendritic cells

(2008) A. R. Mantegazza et al.   BLOOD

Global Sequencing of Proteolytic Cleavage Sites in Apoptosis by Specific Labeling of Protein N Termini

(2008) Sami Mahrus et al.   CELL

Active Caspase-1 Is a Regulator of Unconventional Protein Secretion

(2008) Martin Keller et al.   CELL

Mycobacterium tuberculosis Prevents Inflammasome Activation

(2008) Sharon S. Master et al.   Cell Host & Microbe

The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor

(2008) Sarah E. Ewald et al.   NATURE

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9

(2008) Boyoun Park et al.   NATURE IMMUNOLOGY

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

(2008) Annett Halle et al.   NATURE IMMUNOLOGY