S100A8 and S100A9 Induce Cytokine Expression and Regulate the NLRP3 Inflammasome via ROS-Dependent Activation of NF-κB1

HMGB1 Promotes the Synthesis of Pro-IL-1β and Pro-IL-18 by Activation of p38 MAPK and NF-κB Through Receptors for Advanced Glycation End-products in Macrophages

(2012) Qiang He et al.   Asian Pacific Journal of Cancer Prevention

Oxidized low-density lipoprotein induces secretion of interleukin-1β by macrophages via reactive oxygen species-dependent NLRP3 inflammasome activation

(2012) Yugang Jiang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

TLR-induced NF-κB activation regulates NLRP3 expression in murine macrophages

(2012) Yu Qiao et al.   FEBS LETTERS

IKK biology

(2012) Fei Liu et al.   IMMUNOLOGICAL REVIEWS

Induction of nuclear factor-κB responses by the S100A9 protein is Toll-like receptor-4-dependent

(2012) Matteo Riva et al.   IMMUNOLOGY

Regulation of intracellular signalling through cysteine oxidation by reactive oxygen species

(2012) H. Miki et al.   JOURNAL OF BIOCHEMISTRY

Redox control of NLRP3 inflammasome activation in health and disease

(2012) Anna Rubartelli   JOURNAL OF LEUKOCYTE BIOLOGY

Inflammasomes in health and disease

(2012) Till Strowig et al.   NATURE

The Role of S100a9 in the Pathogenesis of Alzheimer’s Disease: The Therapeutic Effects of S100a9 Knockdown or Knockout

(2012) Keun-A Chang et al.   Neurodegenerative Diseases

S100A9 Interaction with TLR4 Promotes Tumor Growth

(2012) Eva Källberg et al.   PLoS One

An Inflammation Loop Orchestrated by S100A9 and Calprotectin Is Critical for Development of Arthritis

(2012) Annabelle Cesaro et al.   PLoS One

S100A8 and S100A9 in Cardiovascular Biology and Disease

(2011) Michelle M. Averill et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Active involvement of alarmins S100A8 and S100A9 in the regulation of synovial activation and joint destruction during mouse and human osteoarthritis

(2011) Peter L. E. M. van Lent et al.   ARTHRITIS AND RHEUMATISM

NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene B4 in a murine model of gout

(2011) Flávio A. Amaral et al.   ARTHRITIS AND RHEUMATISM

Interleukin-1 in the pathogenesis and treatment of inflammatory diseases

(2011) C. A. Dinarello   BLOOD

Elimination of the NLRP3-ASC Inflammasome Protects against Chronic Obesity-Induced Pancreatic Damage

(2011) Yun-Hee Youm et al.   ENDOCRINOLOGY

Damage-Associated Molecular Pattern S100A9 Increases Bactericidal Activity of Human Neutrophils by Enhancing Phagocytosis

(2011) J.-C. Simard et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Reactive Oxygen Species Inhibitors Block Priming, but Not Activation, of the NLRP3 Inflammasome

(2011) F. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

IL-1: Discoveries, controversies and future directions

(2010) Charles A. Dinarello   EUROPEAN JOURNAL OF IMMUNOLOGY

Critical functions of priming and lysosomal damage for NLRP3 activation

(2010) Veit Hornung et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome

(2010) C. Bauer et al.   GUT

Oxidants Positively or Negatively Regulate Nuclear Factor κB in a Context-dependent Manner

(2010) Noureddine Loukili et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Induction of neutrophil degranulation by S100A9 via a MAPK-dependent mechanism

(2010) Jean-Christophe Simard et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

Immunological and Inflammatory Functions of the Interleukin-1 Family

(2009) Charles A. Dinarello   Annual Review of Immunology

IL-4R , a New Member that Associates with Syk Kinase: Implication in IL-4-Induced Human Neutrophil Functions

(2009) J. Ennaciri et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Oxidative modifications of S100 proteins: functional regulation by redox

(2009) Su Yin Lim et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

(2009) Luigi Franchi et al.   NATURE IMMUNOLOGY

Identification of a novel regulatory region in the interleukin-6 gene promoter

(2008) J.M. Samuel et al.   CYTOKINE

Phagocyte-specific S100 proteins are released from affected mucosa and promote immune responses during inflammatory bowel disease

(2008) D Foell et al.   JOURNAL OF PATHOLOGY