Thioredoxin-interacting protein links oxidative stress to inflammasome activation

Pannexin-1-Mediated Intracellular Delivery of Muramyl Dipeptide Induces Caspase-1 Activation via Cryopyrin/NLRP3 Independently of Nod2

(2014) N. Marina-Garcia et al.   JOURNAL OF IMMUNOLOGY

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome

(2009) Mohamed Lamkanfi et al.   JOURNAL OF CELL BIOLOGY

Subclinical inflammation/oxidation as revealed by altered gene expression profiles in subjects with impaired glucose tolerance and Type 2 diabetes patients

(2009) Kuppan Gokulakrishnan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Malarial Hemozoin Is a Nalp3 Inflammasome Activating Danger Signal

(2009) Catherine Dostert et al.   PLoS One

Glucose and NADPH oxidase drive neuronal superoxide formation in stroke

(2008) Sang Won Suh et al.   ANNALS OF NEUROLOGY

NOD-Like Receptors: Role in Innate Immunity and Inflammatory Disease

(2008) Grace Chen et al.   Annual Review of Pathology-Mechanisms of Disease

Thioredoxin-Interacting Protein: A Critical Link Between Glucose Toxicity and  -Cell Apoptosis

(2008) J. Chen et al.   DIABETES

Thioredoxin Binding Protein-2/Thioredoxin-Interacting Protein Is a Critical Regulator of Insulin Secretion and Peroxisome Proliferator-Activated Receptor Function

(2008) Shin-ichi Oka et al.   ENDOCRINOLOGY

Dendritic cells derived from TBP-2-deficient mice are defective in inducing T cell responses

(2008) Aoi Son et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes

(2008) Junqin Chen et al.   FASEB JOURNAL

The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response

(2008) Daniel A. Muruve et al.   NATURE

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

(2008) Annett Halle et al.   NATURE IMMUNOLOGY

Txnip balances metabolic and growth signaling via PTEN disulfide reduction

(2008) S. T. Y. Hui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE