标题
The biology of ergothioneine, an antioxidant nutraceutical
作者
关键词
-
出版物
NUTRITION RESEARCH REVIEWS
Volume -, Issue -, Pages 1-28
出版商
Cambridge University Press (CUP)
发表日期
2020-02-13
DOI
10.1017/s0954422419000301
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- Production of ergothioneine by Methylobacterium species
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- NF-kappaB Signaling Pathways in Neurological Inflammation: A Mini Review
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- Organic Cation Transporter-Mediated Ergothioneine Uptake in Mouse Neural Progenitor Cells Suppresses Proliferation and Promotes Differentiation into Neurons
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- Genetic and Metabolomic Dissection of the Ergothioneine and Selenoneine Biosynthetic Pathway in the Fission Yeast, S. pombe, and Construction of an Overproduction System
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- Meta-analysis of SLC22A4 and RUNX1 polymorphisms
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- How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusion
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- Crystallization and preliminary X-ray analysis of the ergothioneine-biosynthetic methyltransferase EgtD
- (2014) Allegra Vit et al. Acta Crystallographica Section F-Structural Biology Communications
- Positive effect of mushrooms substituted for meat on body weight, body composition, and health parameters. A 1-year randomized clinical trial
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- Ergothioneine Is a Secreted Antioxidant in Mycobacterium smegmatis
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- Redox activation of Nrf2 & NF-κB: A double end sword?
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- Thiohistidine Biosynthesis
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- Finding novel pharmaceuticals in the systems biology era using multiple effective drug targets, phenotypic screening and knowledge of transporters: where drug discovery went wrong and how to fix it
- (2013) Douglas B. Kell FEBS Journal
- Effect of Chitosan Coating Enriched with Ergothioneine on Quality Changes of Japanese Sea Bass (Lateolabrax japonicas)
- (2013) Luyun Cai et al. Food and Bioprocess Technology
- Anti-inflammatory effects of five commercially available mushroom species determined in lipopolysaccharide and interferon-γ activated murine macrophages
- (2013) Dhanushka Gunawardena et al. FOOD CHEMISTRY
- Knockout of a putative ergothioneine transporter inCaenorhabditis elegansdecreases lifespan and increases susceptibility to oxidative damage
- (2013) I. K. Cheah et al. FREE RADICAL RESEARCH
- 3-Nitrotyrosine: A biomarker of nitrogen free radical species modified proteins in systemic autoimmunogenic conditions
- (2013) Haseeb Ahsan HUMAN IMMUNOLOGY
- The Discovery of the Vitamins
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- Antioxidant Properties of Fruiting Bodies, Mycelia, and Fermented Products of the Culinary-Medicinal King Oyster Mushroom, Pleurotus eryngii (Higher Basidiomycetes), with High Ergothioneine Content
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- Conventional and Novel Applications of Edible Mushrooms in Today's Food Industry
- (2013) B. Moon et al. JOURNAL OF FOOD PROCESSING AND PRESERVATION
- Quantification of L-ergothioneine in human plasma and erythrocytes by liquid chromatography-tandem mass spectrometry
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- Functional Genomics of Novel Secondary Metabolites from Diverse Cyanobacteria Using Untargeted Metabolomics
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- The SLC22 family with transporters of organic cations, anions and zwitterions
- (2013) Hermann Koepsell MOLECULAR ASPECTS OF MEDICINE
- The ABCs of membrane transporters in health and disease (SLC series): Introduction
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- Functional Analysis of Novel Variants in the Organic Cation/Ergothioneine Transporter 1 Identified in Singapore Populations
- (2013) Dorothy Su Lin Toh et al. MOLECULAR PHARMACEUTICS
- A community-driven global reconstruction of human metabolism
- (2013) Ines Thiele et al. NATURE BIOTECHNOLOGY
- Oxidative stress in blood in Alzheimer's disease and mild cognitive impairment: A meta-analysis
- (2013) M. Schrag et al. NEUROBIOLOGY OF DISEASE
- Quaternary ammonium compounds can be abundant in some soils and are taken up as intact molecules by plants
- (2013) Charles R. Warren NEW PHYTOLOGIST
- Plasma L-Ergothioneine Measurement by High-Performance Liquid Chromatography and Capillary Electrophoresis after a Pre-Column Derivatization with 5-Iodoacetamidofluorescein (5-IAF) and Fluorescence Detection
- (2013) Salvatore Sotgia et al. PLoS One
- Strain-specific red blood cell storage, metabolism, and eicosanoid generation in a mouse model
- (2013) James C. Zimring et al. TRANSFUSION
- Metabolic Footprinting of Mutant Libraries to Map Metabolite Utilization to Genotype
- (2012) Richard Baran et al. ACS Chemical Biology
- Introduction: The Diverse and Essential Biological Functions of Vitamins
- (2012) Klaus Kraemer et al. ANNALS OF NUTRITION AND METABOLISM
- Characterization of ergothionase from Burkholderia sp. HME13 and its application to enzymatic quantification of ergothioneine
- (2012) Hisashi Muramatsu et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Glutathione analogs in prokaryotes
- (2012) Robert C. Fahey BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
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- (2012) Tomas Ganz et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
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- (2012) Douglas B. Kell et al. DRUG DISCOVERY TODAY
- Nutraceuticals in the Management of Osteoarthritis
- (2012) Ryan L. Ragle et al. DRUGS & AGING
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- (2012) Lorna Gallagher et al. EUKARYOTIC CELL
- Ergothioneine protects against neuronal injury induced by β-amyloid in mice
- (2012) Nae-Cherng Yang et al. FOOD AND CHEMICAL TOXICOLOGY
- Generation of potentially bioactive ergosterol-derived products following pulsed ultraviolet light exposure of mushrooms (Agaricus bisporus)
- (2012) Michael D. Kalaras et al. FOOD CHEMISTRY
- Nutritional and Medicinal Importance ofPleurotusMushrooms: An Overview
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- Mass appeal: metabolite identification in mass spectrometry-focused untargeted metabolomics
- (2012) Warwick B. Dunn et al. Metabolomics
- The mitochondrial transporter family SLC25: Identification, properties and physiopathology
- (2012) Ferdinando Palmieri MOLECULAR ASPECTS OF MEDICINE
- Strategies of Bacterial Over Expression of Membrane Transporters Relevant in Human Health: The Successful Case of the Three Members of OCTN Subfamily
- (2012) Cesare Indiveri et al. MOLECULAR BIOTECHNOLOGY
- An accelerated workflow for untargeted metabolomics using the METLIN database
- (2012) Ralf Tautenhahn et al. NATURE BIOTECHNOLOGY
- Functional expression of carnitine/organic cation transporter OCTN1 in mouse brain neurons: Possible involvement in neuronal differentiation
- (2012) Noritaka Nakamichi et al. NEUROCHEMISTRY INTERNATIONAL
- Improvement of joint range of motion (ROM) and reduction of chronic pain after consumption of an ergothioneine-containing nutritional supplement
- (2012) Kathleen F. Benson et al. PREVENTIVE MEDICINE
- Functional benefits of ergothioneine and fruit- and vegetable-derived nutraceuticals: Overview of the supplemental issue contents
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- The effects of oxidative stress on female reproduction: a review
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- Kinetics of Ergothioneine Inhibition of Mushroom Tyrosinase
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- Antioxidant activity of food constituents: an overview
- (2011) İlhami Gülçin ARCHIVES OF TOXICOLOGY
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- Proline betaine and its biotransformation products in fasting urine samples are potential biomarkers of habitual citrus fruit consumption
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- Pharmaceutical drug transport: the issues and the implications that it is essentially carrier-mediated only
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- Cyanobacteria produce high levels of ergothioneine
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- Mycobial enhancement of ergothioneine by submerged cultivation of edible mushroom mycelia and its application as an antioxidative compound
- (2011) Pramvadee Tepwong et al. FOOD CHEMISTRY
- Anti-inflammatory activity of methanolic extracts from edible mushrooms in LPS activated RAW 264.7 macrophages
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- In-vitro and in-vivo antioxidant effects of the oyster mushroom Pleurotus ostreatus
- (2011) T. Jayakumar et al. FOOD RESEARCH INTERNATIONAL
- Application of ergothioneine-rich extract from an edible mushroom Flammulina velutipes for melanosis prevention in shrimp, Penaeus monodon and Litopenaeus vannamei
- (2011) Angel B. Encarnacion et al. FOOD RESEARCH INTERNATIONAL
- Clinical trials of antioxidants as cancer prevention agents: Past, present, and future
- (2011) Michael Goodman et al. FREE RADICAL BIOLOGY AND MEDICINE
- The Neurospora crassa mutant NcΔEgt-1 identifies an ergothioneine biosynthetic gene and demonstrates that ergothioneine enhances conidial survival and protects against peroxide toxicity during conidial germination
- (2011) Marco H. Bello et al. FUNGAL GENETICS AND BIOLOGY
- Alterations of red blood cell metabolome in overhydrated hereditary stomatocytosis
- (2011) D. Darghouth et al. HAEMATOLOGICA
- The Effect of Ergothioneine on Clastogenic Potential and Mutagenic Activity
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- Organic Hydroperoxide Resistance Protein and Ergothioneine Compensate for Loss of Mycothiol in Mycobacterium smegmatis Mutants
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- Identification in human urine and blood of a novel selenium metabolite, Se-methylselenoneine, a potential biomarker of metabolization in mammals of the naturally occurring selenoneine, by HPLC coupled to electrospray hybrid linear ion trap-orbital ion trap MS
- (2011) Marlène Klein et al. Metallomics
- Crohn's Disease and Genetic Hitchhiking at IBD5
- (2011) C. D. Huff et al. MOLECULAR BIOLOGY AND EVOLUTION
- Effect of mycelial morphology on ergothioneine production during liquid fermentation of Lentinula edodes
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- Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry
- (2011) Warwick B Dunn et al. Nature Protocols
- Nutraceutical Supplements for Weight Loss
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- The ergothioneine transporter controls and indicates ergothioneine activity — A review
- (2011) Dirk Gründemann PREVENTIVE MEDICINE
- Effect of ergothioneine on acute lung injury and inflammation in cytokine insufflated rats
- (2011) John E. Repine et al. PREVENTIVE MEDICINE
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- (2011) AuBrei J. Weigand-Heller et al. PREVENTIVE MEDICINE
- Nutraceuticals in the treatment of Obsessive Compulsive Disorder (OCD): A review of mechanistic and clinical evidence
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- The Hepcidin-Ferroportin System as a Therapeutic Target in Anemias and Iron Overload Disorders
- (2011) T. Ganz et al. Hematology-American Society of Hematology Education Program
- Metabolic profiling strategy for discovery of nutritional biomarkers: proline betaine as a marker of citrus consumption
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- Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson’s, Huntington’s, Alzheimer’s, prions, bactericides, chemical toxicology and others as examples
- (2010) Douglas B. Kell ARCHIVES OF TOXICOLOGY
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- The antioxidant ascorbic acid mobilizes nuclear copper leading to a prooxidant breakage of cellular DNA: implications for chemotherapeutic action against cancer
- (2010) M. F. Ullah et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Ergothioneine Prevents Copper-Induced Oxidative Damage to DNA and Protein by Forming a Redox-Inactive Ergothioneine−Copper Complex
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- Edible mushrooms: Role in the prevention of cardiovascular diseases
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- Ergothioneine protects against neuronal injury induced by cisplatin both in vitro and in vivo
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- Effects of Ergothioneine from Mushrooms (Flammulina velutipes) on Melanosis and Lipid Oxidation of Kuruma Shrimp (Marsupenaeus japonicus)
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- Identification of a Novel Selenium-containing Compound, Selenoneine, as the Predominant Chemical Form of Organic Selenium in the Blood of Bluefin Tuna
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- Edible Mushroom (Flammulina velutipes) Extract Inhibits Melanosis in Kuruma Shrimp (Marsupenaeus japonicus)
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- An Extract of the Pleurotus ostreatus Mushroom Bolsters the Glutathione Redox System in Various Organs of Aged Rats
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- The Bioactive Agent Ergothioneine, a Key Component of Dietary Mushrooms, Inhibits Monocyte Binding to Endothelial Cells Characteristic of Early Cardiovascular Disease
- (2010) Keith R. Martin JOURNAL OF MEDICINAL FOOD
- In Vitro Reconstitution of Mycobacterial Ergothioneine Biosynthesis
- (2010) Florian P. Seebeck JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Value-added use of mushroom ergothioneine as a colour stabilizer in processed fish meats
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- Membrane transporters in drug development
- (2010) NATURE REVIEWS DRUG DISCOVERY
- Beneficial Effects of Tempeh in Disease Prevention and Treatment
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- Gene Knockout and Metabolome Analysis of Carnitine/Organic Cation Transporter OCTN1
- (2010) Yukio Kato et al. PHARMACEUTICAL RESEARCH
- Evaluation of the safety of the dietary antioxidant ergothioneine using the bacterial reverse mutation assay
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- Original Contribution: Top 10 botanical ingredients in 2010 anti-aging creams
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- The Role of Functional Foods, Nutraceuticals, and Food Supplements in Intestinal Health
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- The Role of Hepcidin in Iron Metabolism
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- Redox Regulation, NF-κB, and Atrial Fibrillation
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- Substrate discrimination by ergothioneine transporter SLC22A4 and carnitine transporter SLC22A5: Gain-of-function by interchange of selected amino acids
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- Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases
- (2009) Douglas B Kell BMC Medical Genomics
- A Review of the Antioxidant Mechanisms of Polyphenol Compounds Related to Iron Binding
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- The unusual amino acid L-ergothioneine is a physiologic cytoprotectant
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- Cosmeceuticals and polyphenols
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- Genetic Variations of the SLC22A4 Gene in Chinese and Indian Populations of Singapore
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- (2009) Nelli G. Markova et al. FREE RADICAL BIOLOGY AND MEDICINE
- Increased ergothioneine tissue concentrations in carriers of the Crohn's disease risk-associated 503F variant of the organic cation transporter OCTN1
- (2009) D Taubert et al. GUT
- Biosynthesis of ergothioneine during different stages of submerged fermentation of “Shiitake” (Lentinus edodes) mushroom and their bioactive properties
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- The topology of drug–target interaction networks: implicit dependence on drug properties and target families
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- Metabolic profiling of the fission yeast S. pombe: quantification of compounds under different temperatures and genetic perturbation
- (2009) Tomáš Pluskal et al. Molecular BioSystems
- Metabonomic characterization of aging and investigation on the anti-aging effects of total flavones of Epimedium
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- Imidazole-Based Erythrocyte Markers of Oxidative Stress in Preeclampsia—An NMR Investigation
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- Pulsatile Stimulation Determines Timing and Specificity of NF- B-Dependent Transcription
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- Functional Characterization of Ergothioneine Transport by Rat Organic Cation/Carnitine Transporter Octn1 (slc22a4)
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- Pleurotus ostreatus, an oyster mushroom, decreases the oxidative stress induced by carbon tetrachloride in rat kidneys, heart and brain
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- Radical-scavenging properties of extracts from the white button mushroom,Agaricus bisporus
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- Biosynthesis and Functions of Mycothiol, the Unique Protective Thiol of Actinobacteria
- (2008) G. L. Newton et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- Mycothiol: synthesis, biosynthesis and biological functions of the major low molecular weight thiol in actinomycetes
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- Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?
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- Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial
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- Characterization of a mycothiol ligase mutant of Rhodococcus jostii RHA1
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- Expression patterns of the organic cation/carnitine transporter family in adult murine brain
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- Ergothioneine Modulates Proinflammatory Cytokines and Heat Shock Protein 70 in Mesenteric Ischemia and Reperfusion Injury
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