Extensive impact of non-antibiotic drugs on human gut bacteria

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug

(2017) Hao Wu et al.   NATURE MEDICINE

Interaction Between Atypical Antipsychotics and the Gut Microbiome in a Bipolar Disease Cohort

(2017) Stephanie A. Flowers et al.   PHARMACOTHERAPY

A tool named Iris for versatile high-throughput phenotyping in microorganisms

(2017) George Kritikos et al.   Nature Microbiology

CART—a chemical annotation retrieval toolkit

(2016) Samy Deghou et al.   BIOINFORMATICS

MOCAT2: a metagenomic assembly, annotation and profiling framework

(2016) Jens Roat Kultima et al.   BIOINFORMATICS

From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

(2016) Ara Koh et al.   CELL

The influence of non-steroidal anti-inflammatory drugs on the gut microbiome

(2016) M.A.M. Rogers et al.   CLINICAL MICROBIOLOGY AND INFECTION

Supersaturation and Precipitation of Posaconazole Upon Entry in the Upper Small Intestine in Humans

(2016) Bart Hens et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Intestinal microbiota in health and disease

(2016) Christina Tobin Kåhrström et al.   NATURE

The microbial pharmacists within us: a metagenomic view of xenobiotic metabolism

(2016) Peter Spanogiannopoulos et al.   NATURE REVIEWS MICROBIOLOGY

Antibiotic use and its consequences for the normal microbiome

(2016) Martin J. Blaser   SCIENCE

Population-level analysis of gut microbiome variation

(2016) Gwen Falony et al.   SCIENCE

Machine Learning Meta-analysis of Large Metagenomic Datasets: Tools and Biological Insights

(2016) Edoardo Pasolli et al.   PLoS Computational Biology

The Challenge of Efflux-Mediated Antibiotic Resistance in Gram-Negative Bacteria

(2015) Xian-Zhi Li et al.   CLINICAL MICROBIOLOGY REVIEWS

Proton pump inhibitors affect the gut microbiome

(2015) Floris Imhann et al.   GUT

Proton pump inhibitors alter the composition of the gut microbiota

(2015) Matthew A Jackson et al.   GUT

Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

(2015) Kristoffer Forslund et al.   NATURE

Gut biogeography of the bacterial microbiota

(2015) Gregory P. Donaldson et al.   NATURE REVIEWS MICROBIOLOGY

The SIDER database of drugs and side effects

(2015) Michael Kuhn et al.   NUCLEIC ACIDS RESEARCH

PubChem Substance and Compound databases

(2015) Sunghwan Kim et al.   NUCLEIC ACIDS RESEARCH

Auranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasis

(2015) Michael B. Harbut et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthase

(2015) Maya A. Farha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The microbiome of uncontacted Amerindians

(2015) J. C. Clemente et al.   Science Advances

Quantification of Gastrointestinal Liquid Volumes and Distribution Following a 240 mL Dose of Water in the Fasted State

(2014) Deanna M. Mudie et al.   MOLECULAR PHARMACEUTICS

Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes

(2014) H Bjørn Nielsen et al.   NATURE BIOTECHNOLOGY

GenoBase: comprehensive resource database of Escherichia coli K-12

(2014) Yuta Otsuka et al.   NUCLEIC ACIDS RESEARCH

The Antipsychotic Olanzapine Interacts with the Gut Microbiome to Cause Weight Gain in Mouse

(2014) Andrew P. Morgan et al.   PLoS One

Cultivation-based multiplex phenotyping of human gut microbiota allows targeted recovery of previously uncultured bacteria

(2014) Elizabeth A. Rettedal et al.   Nature Communications

Imidazoles as Promising Scaffolds for Antibacterial Activity: A Review

(2013) Nidhi Rani et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Accurate and universal delineation of prokaryotic species

(2013) Daniel R Mende et al.   NATURE METHODS

Fasting and postprandial volumes of the undisturbed colon: normal values and changes in diarrhea-predominant irritable bowel syndrome measured using serial MRI

(2013) S. E. Pritchard et al.   NEUROGASTROENTEROLOGY AND MOTILITY

DrugBank 4.0: shedding new light on drug metabolism

(2013) Vivian Law et al.   NUCLEIC ACIDS RESEARCH

STITCH 4: integration of protein–chemical interactions with user data

(2013) Michael Kuhn et al.   NUCLEIC ACIDS RESEARCH

New Substrates on the Block: Clinically Relevant Resistances for EmrE and Homologues

(2012) I. Nasie et al.   JOURNAL OF BACTERIOLOGY

A metagenome-wide association study of gut microbiota in type 2 diabetes

(2012) Junjie Qin et al.   NATURE

Structure, function and diversity of the healthy human microbiome

(2012)   NATURE

Genomic variation landscape of the human gut microbiome

(2012) Siegfried Schloissnig et al.   NATURE

How to Interpret a Functional or Motility Test - Colon Transit Study

(2012) Eun Ran Kim et al.   Journal of Neurogastroenterology and Motility

Phenothiazines as anti-tubercular agents: mechanistic insights and clinical implications

(2011) Sadhna Sharma et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Enterotypes of the human gut microbiome

(2011) Manimozhiyan Arumugam et al.   NATURE

Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy

(2011) Linda Ejim et al.   Nature Chemical Biology

Extensive personal human gut microbiota culture collections characterized and manipulated in gnotobiotic mice

(2011) A. L. Goodman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phenotypic Landscape of a Bacterial Cell

(2010) Robert J. Nichols et al.   CELL

Antimicrobial susceptibility of Bacteroides fragilis group isolates in Europe: 20 years of experience

(2010) E. Nagy et al.   CLINICAL MICROBIOLOGY AND INFECTION

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

Chemotherapy-Induced Modifications to Gastrointestinal Microflora: Evidence and Implications of Change

(2009) Andrea Stringer et al.   CURRENT DRUG METABOLISM

Metformin and the intestine

(2008) C. J. Bailey et al.   DIABETOLOGIA

Drug Target Identification Using Side-Effect Similarity

(2008) M. Campillos et al.   SCIENCE