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Title
Thymic stromal cell subsets for T cell development
Authors
Keywords
Thymus, T cell, Repertoire selection, Thymic epithelial cell, cTEC, mTEC
Journal
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 73, Issue 5, Pages 1021-1037
Publisher
Springer Nature
Online
2016-01-29
DOI
10.1007/s00018-015-2107-8
References
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Note: Only part of the references are listed.- The thymic cortical epithelium determines the TCR repertoire of IL-17-producing T cells
- (2015) T. Nitta et al. EMBO REPORTS
- CCRL1/ACKR4 is expressed in key thymic microenvironments but is dispensable for T lymphopoiesis at steady state in adult mice
- (2015) Beth Lucas et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Natural Th17 cells are critically regulated by functional medullary thymic microenvironments
- (2015) William E. Jenkinson et al. JOURNAL OF AUTOIMMUNITY
- Differential Features of AIRE-Induced and AIRE-Independent Promiscuous Gene Expression in Thymic Epithelial Cells
- (2015) Charles St-Pierre et al. JOURNAL OF IMMUNOLOGY
- Osteoprotegerin-Mediated Homeostasis of Rank+Thymic Epithelial Cells Does Not Limit Foxp3+Regulatory T Cell Development
- (2015) Nicholas I. McCarthy et al. JOURNAL OF IMMUNOLOGY
- TCR affinity for thymoproteasome-dependent positively selecting peptides conditions antigen responsiveness in CD8+ T cells
- (2015) Kensuke Takada et al. NATURE IMMUNOLOGY
- IL-7 coordinates proliferation, differentiation and Tcra recombination during thymocyte β-selection
- (2015) Amine Boudil et al. NATURE IMMUNOLOGY
- Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance
- (2015) S. Yang et al. SCIENCE
- Thymoproteasomes produce unique peptide motifs for positive selection of CD8+ T cells
- (2015) Katsuhiro Sasaki et al. Nature Communications
- CCR7-mediated migration in the thymus controls γδ T-cell development
- (2014) Annika Reinhardt et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Intermediate expression of CCRL1 reveals novel subpopulations of medullary thymic epithelial cells that emerge in the postnatal thymus
- (2014) Ana R. Ribeiro et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Population and single-cell genomics reveal theAiredependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia
- (2014) Stephen N. Sansom et al. GENOME RESEARCH
- Distinct Contributions of Aire and Antigen-Presenting-Cell Subsets to the Generation of Self-Tolerance in the Thymus
- (2014) Justin S.A. Perry et al. IMMUNITY
- Limitation of immune tolerance–inducing thymic epithelial cell development by Spi-B–mediated negative feedback regulation
- (2014) Nobuko Akiyama et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Enhancement of an anti-tumor immune response by transient blockade of central T cell tolerance
- (2014) Imran S. Khan et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The Lymphotoxin Pathway Regulates Aire-Independent Expression of Ectopic Genes and Chemokines in Thymic Stromal Cells
- (2014) N. Seach et al. JOURNAL OF IMMUNOLOGY
- Alterations of the Medullary Epithelial Compartment in the Aire-Deficient Thymus: Implications for Programs of Thymic Epithelial Differentiation
- (2014) J. Dooley et al. JOURNAL OF IMMUNOLOGY
- Checkpoints in the Development of Thymic Cortical Epithelial Cells
- (2014) S. Shakib et al. JOURNAL OF IMMUNOLOGY
- Temporal Lineage Tracing of Aire-Expressing Cells Reveals a Requirement for Aire in Their Maturation Program
- (2014) Y. Nishikawa et al. JOURNAL OF IMMUNOLOGY
- An Essential Role for Medullary Thymic Epithelial Cells during the Intrathymic Development of Invariant NKT Cells
- (2014) A. J. White et al. JOURNAL OF IMMUNOLOGY
- PIX RhoGEF Supports Positive Selection by Restraining Migration and Promoting Arrest of Thymocytes
- (2014) M. Korthals et al. JOURNAL OF IMMUNOLOGY
- The Ability To Rearrange Dual TCRs Enhances Positive Selection, Leading to Increased Allo- and Autoreactive T Cell Repertoires
- (2014) Peggy P. Ni et al. JOURNAL OF IMMUNOLOGY
- The self-obsession of T cells: how TCR signaling thresholds affect fate 'decisions' and effector function
- (2014) Kristin A Hogquist et al. NATURE IMMUNOLOGY
- The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance
- (2014) Michael Waterfield et al. NATURE IMMUNOLOGY
- A regulatory role for TGF-β signaling in the establishment and function of the thymic medulla
- (2014) Mathias Hauri-Hohl et al. NATURE IMMUNOLOGY
- An RNAi screen for Aire cofactors reveals a role for Hnrnpl in polymerase release and Aire-activated ectopic transcription
- (2014) M. Giraud et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aire Deficiency Promotes TRP-1-Specific Immune Rejection of Melanoma
- (2013) M.-L. Zhu et al. CANCER RESEARCH
- Cbx4 regulates the proliferation of thymic epithelial cells and thymus function
- (2013) B. Liu et al. DEVELOPMENT
- Generation of both cortical and Aire+medullary thymic epithelial compartments from CD205+progenitors
- (2013) Song Baik et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Serial progression of cortical and medullary thymic epithelial microenvironments
- (2013) Nuno L. Alves et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- An evolutionarily conserved mutual interdependence between Aire and microRNAs in promiscuous gene expression
- (2013) Olga Ucar et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Foxp3 Transcription Factor Is Proapoptotic and Lethal to Developing Regulatory T Cells unless Counterbalanced by Cytokine Survival Signals
- (2013) Xuguang Tai et al. IMMUNITY
- Thymic medullar conduits-associated podoplanin promotes natural regulatory T cells
- (2013) Elke Fuertbauer et al. IMMUNOLOGY LETTERS
- The thymic medulla is required for Foxp3+regulatory but not conventional CD4+thymocyte development
- (2013) Jennifer E. Cowan et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IRF7-Dependent IFN- Production in Response to RANKL Promotes Medullary Thymic Epithelial Cell Development
- (2013) D. C. Otero et al. JOURNAL OF IMMUNOLOGY
- Thymocyte Selection Regulates the Homeostasis of IL-7-Expressing Thymic Cortical Epithelial Cells In Vivo
- (2013) A. R. Ribeiro et al. JOURNAL OF IMMUNOLOGY
- Lymphotoxin Receptor Regulates the Development of CCL21-Expressing Subset of Postnatal Medullary Thymic Epithelial Cells
- (2013) E. Lkhagvasuren et al. JOURNAL OF IMMUNOLOGY
- Thymic Medullary Epithelium and Thymocyte Self-Tolerance Require Cooperation between CD28-CD80/86 and CD40-CD40L Costimulatory Pathways
- (2013) J. A. Williams et al. JOURNAL OF IMMUNOLOGY
- IL-7 Produced by Thymic Epithelial Cells Plays a Major Role in the Development of Thymocytes and TCR + Intraepithelial Lymphocytes
- (2013) S. Shitara et al. JOURNAL OF IMMUNOLOGY
- TRAF3 enforces the requirement for T cell cross-talk in thymic medullary epithelial development
- (2013) S. R. Jenkinson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Overlapping gene coexpression patterns in human medullary thymic epithelial cells generate self-antigen diversity
- (2013) S. Pinto et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Thymoproteasome subunit- 5T generates peptide-MHC complexes specialized for positive selection
- (2013) Y. Xing et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Murine thymic selection quantified using a unique method to capture deleted T cells
- (2013) G. L. Stritesky et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aire-expressing thymic medullary epithelial cells originate from 5t-expressing progenitor cells
- (2013) I. Ohigashi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
- (2013) S. Malchow et al. SCIENCE
- Lineage Tracing and Cell Ablation Identify a Post-Aire-Expressing Thymic Epithelial Cell Population
- (2013) Todd C. Metzger et al. Cell Reports
- CCX-CKR deficiency alters thymic stroma impairing thymocyte development and promoting autoimmunity
- (2012) M. D. Bunting et al. BLOOD
- Synergistic, Context-Dependent, and Hierarchical Functions of Epithelial Components in Thymic Microenvironments
- (2012) Lesly Calderón et al. CELL
- Development of Interleukin-17-Producing γδ T Cells Is Restricted to a Functional Embryonic Wave
- (2012) Jan D. Haas et al. IMMUNITY
- Plasmacytoid Dendritic Cells Transport Peripheral Antigens to the Thymus to Promote Central Tolerance
- (2012) Husein Hadeiba et al. IMMUNITY
- Rank Signaling Links the Development of Invariant γδ T Cell Progenitors and Aire+ Medullary Epithelium
- (2012) Natalie A. Roberts et al. IMMUNITY
- Autoimmune regulator (Aire) controls the expression of microRNAs in medullary thymic epithelial cells
- (2012) Claudia Macedo et al. IMMUNOBIOLOGY
- Three-Dimensional Visualization of the Mouse Thymus Organization in Health and Immunodeficiency
- (2012) M. Irla et al. JOURNAL OF IMMUNOLOGY
- Identification of IL-7-Producing Cells in Primary and Secondary Lymphoid Organs Using IL-7-GFP Knock-In Mice
- (2012) T. Hara et al. JOURNAL OF IMMUNOLOGY
- MicroRNAs Control the Maintenance of Thymic Epithelia and Their Competence for T Lineage Commitment and Thymocyte Selection
- (2012) S. Zuklys et al. JOURNAL OF IMMUNOLOGY
- Novel Process of Intrathymic Tumor-Immune Tolerance through CCR2-Mediated Recruitment of Sirpα+ Dendritic Cells: A Murine Model
- (2012) Tomohisa Baba et al. PLoS One
- Antigen Recognition By Autoreactive Cd4+ Thymocytes Drives Homeostasis Of The Thymic Medulla
- (2012) Magali Irla et al. PLoS One
- Thymic nurse cells provide microenvironment for secondary T cell receptor rearrangement in cortical thymocytes
- (2012) Y. Nakagawa et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regenerative capacity of adult cortical thymic epithelial cells
- (2012) I. Rode et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Thymic epithelial cells: working class heroes for T cell development and repertoire selection
- (2012) Graham Anderson et al. TRENDS IN IMMUNOLOGY
- The role of the proteasome in the generation of MHC class I ligands and immune responses
- (2011) E. J. A. M. Sijts et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Ontogeny of thymic cortical epithelial cells expressing the thymoproteasome subunit β5t
- (2011) Adiratna Mat Ripen et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Skint-1 Identifies a Common Molecular Mechanism for the Development of Interferon-γ-Secreting versus Interleukin-17-Secreting γδ T Cells
- (2011) Gleb Turchinovich et al. IMMUNITY
- Thymus-specific serine protease controls autoreactive CD4 T cell development and autoimmune diabetes in mice
- (2011) Christophe Viret et al. JOURNAL OF CLINICAL INVESTIGATION
- The requirements for natural Th17 cell development are distinct from those of conventional Th17 cells
- (2011) Jiyeon S. Kim et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development
- (2011) Yu Lei et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Lymphotoxin Signal Promotes Thymic Organogenesis by Eliciting RANK Expression in the Embryonic Thymic Stroma
- (2011) Y. Mouri et al. JOURNAL OF IMMUNOLOGY
- FOXN1 mutation abrogates prenatal T-cell development in humans
- (2011) I. Vigliano et al. JOURNAL OF MEDICAL GENETICS
- The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α receptor
- (2011) Aikaterini S Papadopoulou et al. NATURE IMMUNOLOGY
- Skint-1 is a highly specific, unique selecting component for epidermal T cells
- (2011) S. D. Barbee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells
- (2011) M. Giraud et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aire's Partners in the Molecular Control of Immunological Tolerance
- (2010) Jakub Abramson et al. CELL
- Thymoproteasome Shapes Immunocompetent Repertoire of CD8+ T Cells
- (2010) Takeshi Nitta et al. IMMUNITY
- Thymus-specific serine protease contributes to the diversification of the functional endogenous CD4 T cell receptor repertoire
- (2010) Christophe Viret et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Thymic Stromal Lymphopoietin-Activated Plasmacytoid Dendritic Cells Induce the Generation of FOXP3+ Regulatory T Cells in Human Thymus
- (2010) S. Hanabuchi et al. JOURNAL OF IMMUNOLOGY
- Lymphotoxin Signals from Positively Selected Thymocytes Regulate the Terminal Differentiation of Medullary Thymic Epithelial Cells
- (2010) A. J. White et al. JOURNAL OF IMMUNOLOGY
- Regulation of thymocyte positive selection and motility by GIT2
- (2010) Hyewon Phee et al. NATURE IMMUNOLOGY
- Autonomous role of medullary thymic epithelial cells in central CD4+ T cell tolerance
- (2010) Maria Hinterberger et al. NATURE IMMUNOLOGY
- Neural Crest-Derived Pericytes Promote Egress of Mature Thymocytes at the Corticomedullary Junction
- (2010) M. A. Zachariah et al. SCIENCE
- Role of thymic cortex-specific self-peptides in positive selection of T cells
- (2010) Yousuke Takahama et al. SEMINARS IN IMMUNOLOGY
- Exclusive expression of proteasome subunit 5t in the human thymic cortex
- (2009) U. Tomaru et al. BLOOD
- Absence of thymus crosstalk in the fetus does not preclude hematopoietic induction of a functional thymus in the adult
- (2009) Natalie A. Roberts et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Thymus-specific serine protease regulates positive selection of a subset of CD4+thymocytes
- (2009) Julien Gommeaux et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The thymic medulla: a unique microenvironment for intercellular self-antigen transfer
- (2009) Christian Koble et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cutting Edge: The Chemokine Receptor CXCR3 Retains Invariant NK T Cells in the Thymus
- (2009) M. B. Drennan et al. JOURNAL OF IMMUNOLOGY
- Stabilized -Catenin in Thymic Epithelial Cells Blocks Thymus Development and Function
- (2009) S. Zuklys et al. JOURNAL OF IMMUNOLOGY
- Thymus-Blood Protein Interactions Are Highly Effective in Negative Selection and Regulatory T Cell Induction
- (2009) D. F. Atibalentja et al. JOURNAL OF IMMUNOLOGY
- Autoimmune Regulator Deficiency Results in Decreased Expression of CCR4 and CCR7 Ligands and in Delayed Migration of CD4+ Thymocytes
- (2009) M. Laan et al. JOURNAL OF IMMUNOLOGY
- CXCR4 acts as a costimulator during thymic β-selection
- (2009) Paul C Trampont et al. NATURE IMMUNOLOGY
- Thymic self-reactivity selects natural interleukin 17–producing T cells that can regulate peripheral inflammation
- (2009) Benjamin R Marks et al. NATURE IMMUNOLOGY
- CCR7-mediated migration of developing thymocytes to the medulla is essential for negative selection to tissue-restricted antigens
- (2009) T. Nitta et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Thymus development and function
- (2008) Thomas Boehm CURRENT OPINION IN IMMUNOLOGY
- Intercellular MHC transfer between thymic epithelial and dendritic cells
- (2008) Virginie Millet et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input
- (2008) Andrea J. White et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Thymic Selection Determines γδ T Cell Effector Fate: Antigen-Naive Cells Make Interleukin-17 and Antigen-Experienced Cells Make Interferon γ
- (2008) Kirk D.C. Jensen et al. IMMUNITY
- A Two-Step Process for Thymic Regulatory T Cell Development
- (2008) Chan-Wang Joaquim Lio et al. IMMUNITY
- The Cytokine RANKL Produced by Positively Selected Thymocytes Fosters Medullary Thymic Epithelial Cells that Express Autoimmune Regulator
- (2008) Yu Hikosaka et al. IMMUNITY
- Autoantigen-Specific Interactions with CD4+ Thymocytes Control Mature Medullary Thymic Epithelial Cell Cellularity
- (2008) Magali Irla et al. IMMUNITY
- The Tumor Necrosis Factor Family Receptors RANK and CD40 Cooperatively Establish the Thymic Medullary Microenvironment and Self-Tolerance
- (2008) Taishin Akiyama et al. IMMUNITY
- Delta-like 4 is indispensable in thymic environment specific for T cell development
- (2008) Katsuto Hozumi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment
- (2008) Ute Koch et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Clonal deletion of thymocytes can occur in the cortex with no involvement of the medulla
- (2008) Tom M. McCaughtry et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance
- (2008) Masashi Yano et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance
- (2008) Jelena Nedjic et al. NATURE
- Skint1, the prototype of a newly identified immunoglobulin superfamily gene cluster, positively selects epidermal γδ T cells
- (2008) Lynn M Boyden et al. NATURE GENETICS
- The variable immunological self: Genetic variation and nongenetic noise in Aire-regulated transcription
- (2008) E. S. Venanzi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulatory T Cells: Mechanisms of Differentiation and Function
- (2007) Steven Z. Josefowicz et al. Annual Review of Immunology
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