A nonsynonymousTNFRSF11Avariation increases NFκB activity and the severity of Paget's disease

Collaborative Meta-analysis: Associations of 150 Candidate Genes With Osteoporosis and Osteoporotic Fracture

(2013) J. Brent Richards   ANNALS OF INTERNAL MEDICINE

Contributions of the Measles Virus Nucleocapsid Gene and the SQSTM1/p62P392L Mutation to Paget's Disease

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Genome-wide association identifies three new susceptibility loci for Paget's disease of bone

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The majority of the genetic risk for Paget’s disease of bone is explained by genetic variants close to the CSF1, OPTN, TM7SF4, and TNFRSF11A genes

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Frequency and characteristics of familial aggregation of paget's disease of bone

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Familial aggregation of paget's disease of bone

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Genetic variation in the TNFRSF11A gene encoding RANK is associated with susceptibility to Paget's disease of bone

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SQSTM1 gene analysis and gene-environment interaction in Paget's disease of bone

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Structural and Functional Insights of RANKL-RANK Interaction and Signaling

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Genome-wide association study identifies variants at CSF1, OPTN and TNFRSF11A as genetic risk factors for Paget's disease of bone

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Sequestosome 1 Mutations in Paget's Disease of Bone in Australia: Prevalence, Genotype/Phenotype Correlation, and a Novel Non-UBA Domain Mutation (P364S) Associated With Increased NF-κB Signaling Without Loss of Ubiquitin Binding

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Recent advances in understanding the molecular basis of Paget disease of bone

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Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies

(2009) Fernando Rivadeneira et al.   NATURE GENETICS

Translational research—preventing fractures with denosumab

(2009) Peter R. Ebeling   Nature Reviews Rheumatology

Denosumab for Prevention of Fractures in Postmenopausal Women with Osteoporosis

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Human Osteoclast-Poor Osteopetrosis with Hypogammaglobulinemia due to TNFRSF11A (RANK) Mutations

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Pathogenesis of Paget's disease of bone

(2008) Stuart H. Ralston   BONE

Receptor Activator of Nuclear Factor κB Ligand and Osteoprotegerin Regulation of Bone Remodeling in Health and Disease

(2008) Ann E. Kearns et al.   ENDOCRINE REVIEWS

A SQSTM1/p62 mutation linked to Paget’s disease increases the osteoclastogenic potential of the bone microenvironment

(2008) Yuko Hiruma et al.   HUMAN MOLECULAR GENETICS

Pathogenesis and management of Paget's disease of bone

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