Specific bone cells produce DLL4 to generate thymus-seeding progenitors from bone marrow

Human proT-cells generated in vitro facilitate hematopoietic stem cell-derived T-lymphopoiesis in vivo and restore thymic architecture

(2013) G. Awong et al.   BLOOD

Osteocytes Regulate Primary Lymphoid Organs and Fat Metabolism

(2013) Mari Sato et al.   Cell Metabolism

In vivo fate mapping identifies pre-TCRα expression as an intra- and extrathymic, but not prethymic, marker of T lymphopoiesis

(2013) Hervé Luche et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance

(2013) Adam Greenbaum et al.   NATURE

Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches

(2013) Lei Ding et al.   NATURE

Endogenous Bone Marrow MSCs Are Dynamic, Fate-Restricted Participants in Bone Maintenance and Regeneration

(2012) Dongsu Park et al.   Cell Stem Cell

Stalk Cell Phenotype Depends on Integration of Notch and Smad1/5 Signaling Cascades

(2012) Iván M. Moya et al.   DEVELOPMENTAL CELL

Expression of Functional P-Selectin Glycoprotein Ligand 1 on Hematopoietic Progenitors Is Developmentally Regulated

(2012) D. A. Sultana et al.   JOURNAL OF IMMUNOLOGY

Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF–VEGFR2 signalling

(2012) Rui Benedito et al.   NATURE

Delivery of progenitors to the thymus limits T-lineage reconstitution after bone marrow transplantation

(2011) D. A. Zlotoff et al.   BLOOD

Protein O-fucosyltransferase 1 (Pofut1) regulates lymphoid and myeloid homeostasis through modulation of Notch receptor ligand interactions

(2011) D. Yao et al.   BLOOD

IL-7 mediates Ebf-1-dependent lineage restriction in early lymphoid progenitors

(2011) P. Tsapogas et al.   BLOOD

T Cell Development Critically Depends on Prethymic Stromal Patched Expression

(2011) A. Uhmann et al.   JOURNAL OF IMMUNOLOGY

Notch1 regulates chemotaxis and proliferation by controlling the CC-chemokine receptors 5 and 9 in T cell acute lymphoblastic leukaemia

(2011) Leonardo Mirandola et al.   JOURNAL OF PATHOLOGY

The transcription factors E2A and HEB act in concert to induce the expression of FOXO1 in the common lymphoid progenitor

(2011) E. Welinder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multilayered specification of the T-cell lineage fate

(2010) Ellen V. Rothenberg et al.   IMMUNOLOGICAL REVIEWS

Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the asbmr histomorphometry nomenclature committee

(2010) A. Michael Parfitt et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Direct Comparison of Dll1- and Dll4-Mediated Notch Activation Levels Shows Differential Lymphomyeloid Lineage Commitment Outcomes

(2010) M. Mohtashami et al.   JOURNAL OF IMMUNOLOGY

CC chemokine receptor 7 and 9 double-deficient hematopoietic progenitors are severely impaired in seeding the adult thymus

(2009) A. Krueger et al.   BLOOD

Single-cell analysis of the common lymphoid progenitor compartment reveals functional and molecular heterogeneity

(2009) R. Mansson et al.   BLOOD

Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development

(2009) M. A. Inlay et al.   GENES & DEVELOPMENT

Flk2+ common lymphoid progenitors possess equivalent differentiation potential for the B and T lineages

(2008) H. Karsunky et al.   BLOOD

Delta-like 4 is indispensable in thymic environment specific for T cell development

(2008) Katsuto Hozumi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment

(2008) Ute Koch et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Osteoblastic regulation of B lymphopoiesis is mediated by Gs -dependent signaling pathways

(2008) J. Y. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA