Flowers: precious food and medicine resources

Acteoside, the Main Bioactive Compound in Osmanthus fragrans Flowers, Palliates Experimental Colitis in Mice by Regulating the Gut Microbiota

(2022) Yan Liu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Alkaloids in Future Drug Discovery

(2022) Maria-José U. Ferreira   MOLECULES

Potential active constituents responsible for treating acute pharyngitis in the flowers of Hosta plantaginea (Lam.) Aschers and their pharmacokinetics

(2022) Yu Hu et al.   Food & Function

Ornamental Flowers Grown in Human Surroundings as a Source of Anthocyanins with High Anti-Inflammatory Properties

(2022) Grzegorz Łysiak   Foods

Glucose absorption regulation and mechanism of the compounds in Lilium lancifolium Thunb on Caco-2 cells

(2021) Xiaoqing Xu et al.   FOOD AND CHEMICAL TOXICOLOGY

Rose Flowers—A Delicate Perfume or a Natural Healer?

(2021) Milka Mileva et al.   Biomolecules

Nutraceutical potential of dietary phytochemicals in edible flowers—A review

(2021) Ganesamoorthy Janarny et al.   JOURNAL OF FOOD BIOCHEMISTRY

Essential Oils as Natural Sources of Fragrance Compounds for Cosmetics and Cosmeceuticals

(2021) Jugreet B. Sharmeen et al.   MOLECULES

Bioactive phenolic compounds from the flowers of Farfugium japonicum (L.) Kitam. var. giganteum (Siebold et Zucc.) Kitam. (Asteraceae)

(2021) Hari Prasad Devkota et al.   NATURAL PRODUCT RESEARCH

Isolation, Characterization and Antioxidant, Tyrosinase Inhibitory Activities of Constituents from the Flowers of Cercis glabra ‘Spring-1’

(2021) Penghua Shu et al.   Records of Natural Products

Spectrum-effect relationship of immunologic activity of Ganoderma lucidum by UPLC-MS/MS and component knock-out method

(2021) Changqin Li et al.   Food Science and Human Wellness

Terpenoids’ anti-cancer effects: focus on autophagy

(2021) Chirine El-Baba et al.   APOPTOSIS

Antrodia cinnamomea exerts an anti-hepatoma effect by targeting PI3K/AKT-mediated cell cycle progression in vitro and in vivo

(2021) Yan Zhang et al.   Acta Pharmaceutica Sinica B

Plantanone C attenuates LPS-stimulated inflammation by inhibiting NF-κB/iNOS/COX-2/MAPKs/Akt pathways in RAW 264.7 macrophages

(2021) Yiwei Fang et al.   BIOMEDICINE & PHARMACOTHERAPY

Hostaflavone A from Hosta plantaginea (Lam.) Asch. blocked NF-κB/iNOS/COX-2/MAPKs/Akt signaling pathways in LPS-induced RAW 264.7 macrophages

(2021) Li Yang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Anti-diabetic effects of linarin from Chrysanthemi Indici Flos via AMPK activation

(2021) Zhen-ji Wang et al.   Chinese Herbal Medicines

Structures and Inhibitory Activities for Interleukin-2 Production of Seasonally Variable Constituents in Flower Parts of Magnolia kobus at Different Growth Stages

(2020) Naohiro Oshima et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Discovering the Major Antitussive, Expectorant, and Anti-Inflammatory Bioactive Constituents in Tussilago farfara L. Based on the Spectrum–Effect Relationship Combined with Chemometrics

(2020) Liu Yang et al.   MOLECULES

Evaluation Procoagulant Activity and Mechanism of Astragalin

(2020) Changqin Li et al.   MOLECULES

Plantanone D, a new rare methyl-flavonoid from the flowers of Hosta plantaginea with anti-inflammatory and antioxidant activities

(2020) Li Yang et al.   NATURAL PRODUCT RESEARCH

Edgeworthia gardneri (Wall.) Meisn. Water Extract Ameliorates Palmitate Induced Insulin Resistance by Regulating IRS1/GSK3β/FoxO1 Signaling Pathway in Human HepG2 Hepatocytes

(2020) Yi Zhang et al.   Frontiers in Pharmacology

Sesquiterpenoids isolated from the flower of Inula japonica as potential antitumor leads for intervention of paclitaxel-resistant non-small-cell lung cancer

(2020) Yahui Ding et al.   BIOORGANIC CHEMISTRY

Flavones from the Flowers of Tridax Procumbens and their Antioxidant Activity

(2020) Shuai Ma et al.   CHEMISTRY OF NATURAL COMPOUNDS

Isolation and characterization of flavonoid derivatives with anti-prostate cancer and hepatoprotective activities from the flowers of Hosta plantaginea (Lam.) Aschers

(2020) Rongrui Wei et al.   JOURNAL OF ETHNOPHARMACOLOGY

A new nitrogen-containing iridoid glycoside from lonicera macranthoides

(2020) Yu-Dan Mei et al.   NATURAL PRODUCT RESEARCH

Galuteolin, identified in the extract of thymus quinquecostatus flowers, is involved in inhibiting melanin biosynthesis in B16/F10 melanoma cells

(2020) Mi-Hee Kim et al.   NATURAL PRODUCT RESEARCH

Tussilagone Inhibits Osteoclastogenesis and Periprosthetic Osteolysis by Suppressing the NF-κB and P38 MAPK Signaling Pathways

(2020) Xuantao Hu et al.   Frontiers in Pharmacology

Potential implications of polyphenols on aging considering oxidative stress, inflammation, autophagy, and gut microbiota

(2020) Min Wu et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Recent Research on Flavonoids and their Biomedical applications

(2020) Kui Cheng et al.   CURRENT MEDICINAL CHEMISTRY

Antiplatelet Activity of Tussilagone via Inhibition of the GPVI Downstream Signaling Pathway in Platelets

(2020) Jing Zhou et al.   Frontiers in Medicine

Growth-Inhibiting, Bactericidal, Antibiofilm, and Urease Inhibitory Activities of Hibiscus rosa sinensis L. Flower Constituents toward Antibiotic Sensitive- and Resistant-Strains of Helicobacter pylori

(2020) Hieu Tran Trung et al.   ACS Omega

Chemical composition and glucose uptake effect on 3T3-L1 adipocytes of Ligustrum lucidum Ait. flowers

(2020) Lili Cui et al.   Food Science and Human Wellness

Indole Alkaloids from Hosta plantaginea and Inhibition of Steroid 5α-Reductase Activities In Vitro

(2020) Rongrui Wei et al.   CHEMISTRY OF NATURAL COMPOUNDS

Potential anti-diabetic isoprenoids and a long-chain δ-lactone from frangipani (Plumeria rubra)

(2020) Sheng-Nan Zhang et al.   FITOTERAPIA

Prenylated indole alkaloids and lignans from the flower buds of Tussilago farfara

(2020) Xiu-Qing Song et al.   FITOTERAPIA

Identification and characterization of anti-diabetic principle in Senna alata (Linn.) flower using alloxan-induced diabetic male Wistar rats

(2020) Judith Nkechiyere Uwazie et al.   JOURNAL OF ETHNOPHARMACOLOGY

Constituents of Coreopsis lanceolata Flower and Their Dipeptidyl Peptidase IV Inhibitory Effects

(2020) Bo-Ram Kim et al.   MOLECULES

Three New Oleanane-Type Triterpenoidal Glycosides from Impatiens balsamina and Their Biological Activity

(2020) Tae Hyun Lee et al.   Plants-Basel

Five new phenylpropanoid glycosides from the flowers of Paulownia fortunei and their antioxidant activities

(2020) Jingke Zhang et al.   Phytochemistry Letters

Antimicrobial polycyclic polyprenylated acylphoroglucinols from Mesua ferrea flower

(2020) Xiao-Chun Zhang et al.   Phytochemistry Letters

Edible flowers as functional raw materials: A review on anti-aging properties

(2020) Qi Chen et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Antioxidant and α-glucosidase inhibitiory activity of Cercis chinensis flowers

(2020) Juanjuan Zhang et al.   Food Science and Human Wellness

Combining UPLC/Q-TOF-MS/MS With Biological Evaluation for NF-κB Inhibitors in Uyghur Medicine Althaea rosea Flowers

(2019) Fang Ma et al.   Frontiers in Plant Science

In vitro wound healing activity of 1-hydroxy-5,7-dimethoxy-2-naphthalene-carboxaldehyde (HDNC) and other isolates of Aegle marmelos L.: Enhances keratinocytes motility via Wnt/β-catenin and RAS-ERK pathways

(2019) Lubna Azmi et al.   SAUDI PHARMACEUTICAL JOURNAL

New Caffeoylquinic Acid Derivatives and Flavanone Glycoside from the Flowers of Chrysanthemum morifolium and Their Bioactivities

(2019) Peng-Fei Yang et al.   MOLECULES

Epimagnolin A inhibits IL‐6 production by inhibiting p38/NF‐κB and AP‐1 signaling pathways in PMA‐stimulated THP‐1 cells

(2019) Hyun‐Woo Chun et al.   ENVIRONMENTAL TOXICOLOGY

Lanceoleins A–G, hydroxychalcones, from the flowers of Coreopsis lanceolata and their chemopreventive effects against human colon cancer cells

(2019) Hyoung-Geun Kim et al.   BIOORGANIC CHEMISTRY

Antioxidant constituents of chrysanthemum ‘jinsidaju’ cultivated in Kaifeng

(2019) Fenqin Zhao et al.   FITOTERAPIA

New insights into antioxidant activity of Prunus spinosa flowers: Extracts, model polyphenols and their phenolic metabolites in plasma towards multiple in vivo-relevant oxidants

(2019) Anna Marchelak et al.   Phytochemistry Letters

Promising activity of Anthemis austriaca Jacq. on the endometriosis rat model and isolation of its active constituents

(2019) Mert Ilhan et al.   SAUDI PHARMACEUTICAL JOURNAL

Identification and quantitative analysis of phenolic glycosides with antioxidant activity in methanolic extract of Dendrobium catenatum flowers and selection of quality control herb-markers

(2019) Xinfeng Zhang et al.   FOOD RESEARCH INTERNATIONAL

In vitro antibacterial, antioxidant, anti-inflammatory and analgesic evaluation of Rosmarinus officinalis L. flower extract fractions

(2019) A.E. Karadağ et al.   SOUTH AFRICAN JOURNAL OF BOTANY

Chemical constituents from Lonicera japonica flower buds and their anti-hepatoma and anti-HBV activities

(2019) Lanlan Ge et al.   BIOORGANIC CHEMISTRY

Bioactive sesquiterpenoids and sesquiterpenoid glucosides from the flowers of Inula japonica

(2019) Zhi-Pu Yu et al.   FITOTERAPIA

Spectrum-effect relationship of antioxidant and tyrosinase activity with Malus pumila flowers by UPLC-MS/MS and component knock-out method

(2019) Wenjing Li et al.   FOOD AND CHEMICAL TOXICOLOGY

Identification of the main active antidepressant constituents in a traditional Turkish medicinal plant, Centaurea kurdica Reichardt

(2019) Fatma Tuğçe Gürağaç Dereli et al.   JOURNAL OF ETHNOPHARMACOLOGY

BBB-permeable aporphine-type alkaloids in Nelumbo nucifera flowers with accelerative effects on neurite outgrowth in PC-12 cells

(2019) Mamiko Yano et al.   Journal of Natural Medicines

(R)-3-(8'-Hydroxyfarnesyl)-indole and other chemical constituents from the flowers of Anomianthus dulcis and their antimalarial and cytotoxic activities

(2019) Thanika Promchai et al.   NATURAL PRODUCT RESEARCH

Edible flowers: Emerging components in the diet

(2019) Tânia C.S. P. Pires et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Five new compounds from Hosta plantaginea flowers and their anti-inflammatory activities

(2019) Ying Zhang et al.   BIOORGANIC CHEMISTRY

Edible flowers: Bioactive profile and its potential to be used in food development

(2019) Jacqueline Aparecida Takahashi et al.   FOOD RESEARCH INTERNATIONAL

Tussilagonone Ameliorates Psoriatic Features in Keratinocytes and Imiquimod-Induced Psoriasis-Like Lesions in Mice via NRF2 Activation

(2019) Joohee Lee et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Hostaflavanol A, a new anti-inflammatory and antioxidant activities flavanol from the flowers of Hosta plantaginea

(2019) Li Yang et al.   MEDICINAL CHEMISTRY RESEARCH

Inunicosides A−K, rare polyacylated ent-kaurane diterpenoid glycosides from the flowers of Inula japonica

(2019) Zhi-Pu Yu et al.   TETRAHEDRON

Japonicone V, a sesquiterpene lactone derivative from the flowers of Inula japonica, inhibits hepatitis E virus replication by targeting virus-associated autophagy

(2019) Yueliang Zhao et al.   Journal of Functional Foods

NO inhibitors function as potential anti-neuroinflammatory agents for AD from the flowers of Inula japonica

(2018) Feng Liu et al.   BIOORGANIC CHEMISTRY

Eudesmanolides and Other Constituents from the Flowers of Wedelia trilobata

(2018) Yang Hui et al.   CHEMISTRY & BIODIVERSITY

Antithrombotic components of Malus halliana Koehne flowers

(2018) Lili Cui et al.   FOOD AND CHEMICAL TOXICOLOGY

Total phenolics and antioxidants profiles of commonly consumed edible flowers in China

(2018) Jingyun Zheng et al.   INTERNATIONAL JOURNAL OF FOOD PROPERTIES

A new flavonol glycoside from the flowers of Hosta plantaginea with cyclooxygenases-1/2 inhibitory and antioxidant activities

(2018) Junwei He et al.   NATURAL PRODUCT RESEARCH

Chemical constituents from the flowers of Satsuma mandarin and their free radical scavenging and α-glucosidase inhibitory activities

(2018) Anjana Adhikari-Devkota et al.   NATURAL PRODUCT RESEARCH

Phenolic glycoside constituents from Brassica rapa flowers and their α-glucosidase inhibitory activity

(2018) Chun-Chao Zhao et al.   NATURAL PRODUCT RESEARCH

Three new 3,4- seco -cycloartane triterpenoids from the flower of Gardenia jasminoides

(2018) Li-Sha Zhang et al.   Phytochemistry Letters

Epimagnolin A, a tetrahydrofurofuranoid lignan from Magnolia fargesii , reverses ABCB1-mediated drug resistance

(2018) Yuji Mitani et al.   PHYTOMEDICINE

Islet protection and amelioration of type 2 diabetes mellitus by treatment with quercetin from the flowers of Edgeworthia gardneri

(2018) Manjiao Zhuang et al.   Drug Design Development and Therapy

Tussilagone, a major active component in Tussilago farfara, ameliorates inflammatory responses in dextran sulphate sodium-induced murine colitis

(2018) Hye Jin Cheon et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Dimeric- and trimeric sesquiterpenes from the flower of Inula japonica

(2018) Qinghao Jin et al.   PHYTOCHEMISTRY

Lignans Isolated From Flower Buds of Magnolia fargesii Attenuate Airway Inflammation Induced by Cigarette Smoke in vitro and in vivo

(2018) Su-Ui Lee et al.   Frontiers in Pharmacology

Coagulatory active constituents of Malus pumila Mill. flowers

(2018) Zhenhua Yin et al.   Chemistry Central Journal

Target discovery of chlorogenic acid derivatives from the flower buds of Lonicera macranthoides and their MAO B inhibitory mechanism

(2018) Yudan Mei et al.   FITOTERAPIA

Identification of anti-nociceptive constituents from the pollen of Typha angustifolia L. using effect-directed fractionation

(2018) Guangyao Zeng et al.   NATURAL PRODUCT RESEARCH

Six new dammarane-type triterpene saponins from Panax ginseng flower buds and their cytotoxicity

(2018) Ke-Ke Li et al.   Journal of Ginseng Research

A new constituent against rheumatoid arthritis from the flower buds of Lonicera japonica

(2018) Yu Xiao et al.   Phytochemistry Letters

Six new compounds from the flowers of Chrysanthemum morifolium and their biological activities

(2018) Peng-Fei Yang et al.   BIOORGANIC CHEMISTRY

Anti-inflammatory Effect of Essential Oil from Citrus aurantium L. var. amara Engl

(2017) Chun-Yan Shen et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Extraction and isolation of potential anti-stroke compounds from flowers of Pueraria lobata guided by in vitro PC12 cell model

(2017) Sainan Li et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Edible flowers: A review of the nutritional, antioxidant, antimicrobial properties and effects on human health

(2017) Luana Fernandes et al.   JOURNAL OF FOOD COMPOSITION AND ANALYSIS

Chemical Constituents from the Flower of Hosta plantaginea with Cyclooxygenases Inhibition and Antioxidant Activities and Their Chemotaxonomic Significance

(2017) Li Yang et al.   MOLECULES

Flavonoids isolated from the flowers of Limonium bicolor and their in vitro antitumor evaluation

(2017) Linshan Wang et al.   Pharmacognosy Magazine

Fargesin exerts anti-inflammatory effects in THP-1 monocytes by suppressing PKC-dependent AP-1 and NF-ĸB signaling

(2017) Thu-Huyen Pham et al.   PHYTOMEDICINE

Biotechnological Advancements for Improving Floral Attributes in Ornamental Plants

(2017) Ali Noman et al.   Frontiers in Plant Science

Antioxidant Activities and Chemical Constituents of Flavonoids from the Flower of Paeonia ostii

(2016) Huifang Zhang et al.   MOLECULES

Bioactive sesquiterpenoids from the flowers of Inula japonica

(2016) Xing-De Wu et al.   PHYTOCHEMISTRY

Phytochemical Content, Health Benefits, and Toxicology of Common Edible Flowers: A Review (2000–2015)

(2015) Baiyi Lu et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Hypoglycemic activity evaluation and chemical study on hollyhock flowers

(2015) Yi Zhang et al.   FITOTERAPIA

Coumarins with α-glucosidase and α-amylase inhibitory activities from the flower of Edgeworthia gardneri

(2015) Deng-Gao Zhao et al.   FITOTERAPIA

Edible Flowers: A Rich Source of Phytochemicals with Antioxidant and Hypoglycemic Properties

(2015) Monica Rosa Loizzo et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The Anti-Osteoporosis and Antioxidant Activities of Chemical Constituents fromChrysanthemum indicumFlowers

(2015) Bui Thi Thuy Luyen et al.   PHYTOTHERAPY RESEARCH

Isolation, Characterization and Activity of the Flowers ofRhododendron arboreum(Ericaceae)

(2012) Pankaj Kumar Sonar et al.   E-Journal of Chemistry

Antioxidant activity and chemical constituents of edible flower of Sophora viciifolia

(2010) Zhigang Tai et al.   FOOD CHEMISTRY

Structurally related cytotoxic effects of flavonoids on human cancer cells in vitro

(2008) Hui Chang et al.   ARCHIVES OF PHARMACAL RESEARCH