Janus kinase inhibitors are potential therapeutics for amyotrophic lateral sclerosis

The Distinct Effects of the Mitochondria-Targeted STAT3 Inhibitors Mitocur-1 and Mitocur-3 on Mast Cell and Mitochondrial Functions

(2023) Anastasia N. Pavlyuchenkova et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IL-6/ERK signaling pathway participates in type I IFN-programmed, unconventional M2-like macrophage polarization

(2023) Limin Yang et al.   Scientific Reports

Selective Neuronal Knockout of STAT3 Function Inhibits Epilepsy Progression, Improves Cognition, and Restores Dysregulated Gene Networks in a Temporal Lobe Epilepsy Model

(2023) Allison E. Tipton et al.   ANNALS OF NEUROLOGY

Blockage of STAT3 during epileptogenesis prevents GABAergic loss and imprinting of the epileptic state

(2023) Soraya Martín-Suárez et al.   BRAIN

PIKFYVE inhibition mitigates disease in models of diverse forms of ALS

(2023) Shu-Ting Hung et al.   CELL

Regulatory T cells promote functional recovery after spinal cord injury by alleviating microglia inflammation via STAT3 inhibition

(2023) Rui Liu et al.   CNS Neuroscience & Therapeutics

Cationic amphiphilic antihistamines inhibit STAT3 via Ca2+-dependent lysosomal H+ efflux

(2023) Bin Liu et al.   Cell Reports

Baricitinib Treatment of Coronavirus Disease 2019 Is Associated With a Reduction in Secondary Infections

(2023) Daniel A Sweeney et al.   Open Forum Infectious Diseases

Melatonin protects against cadmium-induced oxidative stress via mitochondrial STAT3 signaling in human prostate stromal cells

(2023) Moonjung Hyun et al.   Communications Biology

Loss of fatty acid degradation by astrocytic mitochondria triggers neuroinflammation and neurodegeneration

(2023) Yashi Mi et al.   Nature Metabolism

Cortical hyperexcitability in amyotrophic lateral sclerosis: from pathogenesis to diagnosis

(2023) Hannah C. Timmins et al.   CURRENT OPINION IN NEUROLOGY

Pathologically mislocalised TDP-43 in upper motor neurons causes a die-forward spread of ALS-like pathogenic changes throughout the mouse corticomotor system

(2023) Laura A. Reale et al.   PROGRESS IN NEUROBIOLOGY

Ruxolitinib attenuates secondary injury after traumatic spinal cord injury

(2022) Hai-Jun Li et al.   Neural Regeneration Research

Cardiovascular and Cancer Risk with Tofacitinib in Rheumatoid Arthritis

(2022) Steven R. Ytterberg et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tofacitinib Suppresses Natural Killer Cells In Vitro and In Vivo: Implications for Amyotrophic Lateral Sclerosis

(2022) Claudia Figueroa-Romero et al.   Frontiers in Immunology

IL-6/STAT3 Signaling Promotes Cardiac Dysfunction by Upregulating FUNDC1-Dependent Mitochondria-Associated Endoplasmic Reticulum Membranes Formation in Sepsis Mice

(2022) Tao Jiang et al.   Frontiers in Cardiovascular Medicine

Emerging insights into the complex genetics and pathophysiology of amyotrophic lateral sclerosis

(2022) Stephen A Goutman et al.   LANCET NEUROLOGY

Oral surveillance and JAK inhibitor safety: the theory of relativity

(2022) Kevin L. Winthrop et al.   Nature Reviews Rheumatology

The Interaction Between Autophagy and JAK/STAT3 Signaling Pathway in Tumors

(2022) Jiangyan Xu et al.   Frontiers in Genetics

The Interplay Between Autophagy and RNA Homeostasis: Implications for Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

(2022) O. H. Houghton et al.   Frontiers in Cell and Developmental Biology

Changes of Gene Expression Patterns of Muscle Pathophysiology-Related Transcription Factors During Denervated Muscle Atrophy

(2022) Xiaoming Yang et al.   Frontiers in Physiology

The AI-Assisted Identification and Clinical Efficacy of Baricitinib in the Treatment of COVID-19

(2022) Peter J. Richardson et al.   Vaccines

Integrative transcriptomic analysis of the amyotrophic lateral sclerosis spinal cord implicates glial activation and suggests new risk genes

(2022) Jack Humphrey et al.   NATURE NEUROSCIENCE

Amyotrophic lateral sclerosis: a neurodegenerative disorder poised for successful therapeutic translation

(2022) Richard J. Mead et al.   NATURE REVIEWS DRUG DISCOVERY

TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS

(2021) Xinxin Zuo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Improving mitochondria and ER stability helps eliminate upper motor neuron degeneration that occurs due to mSOD1 toxicity and TDP‐43 pathology

(2021) Barış Genç et al.   Clinical and Translational Medicine

The Links between ALS and NF-κB

(2021) Emma Källstig et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitochondrial dysfunction and traffic jams in amyotrophic lateral sclerosis

(2021) Rishabh Jhanji et al.   MITOCHONDRION

An activity-dependent determinant of synapse elimination in the mammalian brain

(2021) Masahiro Yasuda et al.   NEURON

Muscle Function Differences between Patients with Bulbar and Spinal Onset Amyotrophic Lateral Sclerosis. Does It Depend on Peripheral Glucose?

(2021) Jose Enrique de la Rubia Ortí et al.   Journal of Clinical Medicine

Astrocyte‐selective STAT3 knockdown rescues methamphetamine withdrawal‐disrupted spatial memory in mice via restoring the astrocytic capacity of glutamate clearance in dCA1

(2021) Pengbo Shi et al.   GLIA

TDP-43 and Inflammation: Implications for Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

(2021) Fiona Bright et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Niclosamide affects intracellular TDP-43 distribution in motor neurons, activates mitophagy, and attenuates morphological changes under stress

(2021) Yosuke Kato et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Glial Metabolic Reprogramming in Amyotrophic Lateral Sclerosis

(2021) Patricia Cassina et al.   NEUROIMMUNOMODULATION

Cortical hyperexcitability: Diagnostic and pathogenic biomarker of ALS

(2021) Steve Vucic et al.   NEUROSCIENCE LETTERS

Rationale and Design of a Mechanistic Clinical Trial of JAK inhibition to Prevent Ventilator-Induced Diaphragm Dysfunction

(2021) Joseph B. Shrager et al.   RESPIRATORY MEDICINE

Genome-encoded cytoplasmic double-stranded RNAs, found in C9ORF72 ALS-FTD brain, propagate neuronal loss

(2021) Steven Rodriguez et al.   Science Translational Medicine

Perturbed BMP signaling and denervation promote muscle wasting in cancer cachexia

(2021) Roberta Sartori et al.   Science Translational Medicine

Expert-Augmented Computational Drug Repurposing Identified Baricitinib as a Treatment for COVID-19

(2021) Daniel P. Smith et al.   Frontiers in Pharmacology

Efficacy and safety of baricitinib for the treatment of hospitalised adults with COVID-19 (COV-BARRIER): a randomised, double-blind, parallel-group, placebo-controlled phase 3 trial

(2021) Vincent C Marconi et al.   Lancet Respiratory Medicine

Astrocytes display cell autonomous and diverse early reactive states in familial amyotrophic lateral sclerosis

(2021) Doaa M Taha et al.   BRAIN

Local and remote interactions between macrophages and microglia in neurological conditions

(2021) Séverine Boillée   CURRENT OPINION IN IMMUNOLOGY

Meta-analysis of human and mouse ALS astrocytes reveals multi-omic signatures of inflammatory reactive states

(2021) Oliver J. Ziff et al.   GENOME RESEARCH

Structural exploration with AlphaFold2-generated STAT3α structure reveals selective elements in STAT3α-GRIM-19 interactions involved in negative regulation

(2021) Seema Mishra et al.   Scientific Reports

Global characterization of macrophage polarization mechanisms and identification of M2-type polarization inhibitors

(2021) Lizhi He et al.   Cell Reports

Neuroinflammation and Scarring After Spinal Cord Injury: Therapeutic Roles of MSCs on Inflammation and Glial Scar

(2021) Qi-Ming Pang et al.   Frontiers in Immunology

STAT3 as a mediator of oncogenic cellular metabolism: Pathogenic and therapeutic implications

(2021) Isidora Tošić et al.   NEOPLASIA

Baricitinib as potential treatment for 2019-nCoV acute respiratory disease

(2020) Peter Richardson et al.   LANCET

COVID-19: combining antiviral and anti-inflammatory treatments

(2020) Justin Stebbing et al.   LANCET INFECTIOUS DISEASES

Mitochondrial fission and fusion: A dynamic role in aging and potential target for age-related disease

(2020) Yasmine J. Liu et al.   MECHANISMS OF AGEING AND DEVELOPMENT

ID1 confers cancer cell chemoresistance through STAT3/ATF6-mediated induction of autophagy

(2020) Jiao Meng et al.   Cell Death & Disease

STAT 3 ‐dependent analysis reveals PDK 4 as independent predictor of recurrence in prostate cancer

(2020) Monika Oberhuber et al.   Molecular Systems Biology

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

(2020) David E. Gordon et al.   NATURE

Updates and challenges of axon regeneration in the mammalian central nervous system

(2020) Cheng Qian et al.   Journal of Molecular Cell Biology

Natural killer cells modulate motor neuron-immune cell cross talk in models of Amyotrophic Lateral Sclerosis

(2020) Stefano Garofalo et al.   Nature Communications

Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2

(2020) Yadi Zhou et al.   Cell Discovery

Combined anti-fibrotic and anti-inflammatory properties of JAK-inhibitors on macrophages in vitro and in vivo: Perspectives for scleroderma-associated interstitial lung disease

(2020) Alain Lescoat et al.   BIOCHEMICAL PHARMACOLOGY

Amyotrophic lateral sclerosis: a clinical review

(2020) P. Masrori et al.   EUROPEAN JOURNAL OF NEUROLOGY

Repurpose Open Data to Discover Therapeutics for COVID-19 Using Deep Learning

(2020) Xiangxiang Zeng et al.   JOURNAL OF PROTEOME RESEARCH

Review: Microglia in motor neuron disease

(2020) B. A. Ashford et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Metformin inhibits RAN translation through PKR pathway and mitigates disease inC9orf72ALS/FTD mice

(2020) Tao Zu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1β expression

(2020) Jesse J. Balic et al.   Nature Communications

A review of computational drug repositioning: strategies, approaches, opportunities, challenges, and directions

(2020) Tamer N. Jarada et al.   Journal of Cheminformatics

Real-world evidence of riluzole effectiveness in treating amyotrophic lateral sclerosis

(2020) Jinsy A. Andrews et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS

(2020) Chien-Hsiung Yu et al.   CELL

Phosphorylation of STAT3 by axonal Cdk5 promotes axonal regeneration by modulating mitochondrial activity

(2020) Jinyeon Hwang et al.   EXPERIMENTAL NEUROLOGY

Modifying macrophages at the periphery has the capacity to change microglial reactivity and to extend ALS survival

(2020) Aude Chiot et al.   NATURE NEUROSCIENCE

Preclinical validation of therapeutic targets predicted by tensor factorization on heterogeneous graphs

(2020) Saee Paliwal et al.   Scientific Reports

Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques

(2020) Timothy N. Hoang et al.   CELL

Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19

(2020) Andre C. Kalil et al.   NEW ENGLAND JOURNAL OF MEDICINE

Skeletal Muscle-Restricted Expression of Human SOD1 in Transgenic Mice Causes a Fatal ALS-Like Syndrome

(2020) Lee J. Martin et al.   Frontiers in Neurology

Inhibition of IL-6/JAK/STAT3 pathway rescues denervation-induced skeletal muscle atrophy

(2020) Ziwei Huang et al.   Annals of Translational Medicine

Regulation of Skeletal Muscle DRP-1 and FIS-1 Protein Expression by IL-6 Signaling

(2019) Dennis K. Fix et al.   Oxidative Medicine and Cellular Longevity

The JAK/STAT Pathway in Skeletal Muscle Pathophysiology

(2019) Viviana Moresi et al.   Frontiers in Physiology

Epidemiology of amyotrophic lateral sclerosis

(2019) Elisa Longinetti et al.   CURRENT OPINION IN NEUROLOGY

Critical appraisal of STAT3 pattern in adult cardiomyocytes

(2019) Zeina Harhous et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Motor Neuron Susceptibility in ALS/FTD

(2019) Audrey M. G. Ragagnin et al.   Frontiers in Neuroscience

MCP1-CCR2 and neuroinflammation in the ALS motor cortex with TDP-43 pathology

(2019) Javier H. Jara et al.   Journal of Neuroinflammation

Hemorrhagic Shock Sensitized the Diaphragm to Ventilator-Induced Dysfunction through the Activation of IL-6/JAK/STAT Signaling-Mediated Autophagy in Rats

(2019) Li-Juan Zhang et al.   MEDIATORS OF INFLAMMATION

Stress granules and neurodegeneration

(2019) Benjamin Wolozin et al.   NATURE REVIEWS NEUROSCIENCE

Molecular Insight Into the IRE1α-Mediated Type I Interferon Response Induced by Proteasome Impairment in Myeloid Cells of the Brain

(2019) Maja Studencka-Turski et al.   Frontiers in Immunology

Modulation of allergic responses by mitochondrial STAT3 inhibitors

(2018) Tal Erlich et al.   ALLERGY

A New Perspective: Mitochondrial Stat3 as a Regulator for Lymphocyte Function

(2018) Mercedes Rincon et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Denervation-activated STAT3–IL-6 signalling in fibro-adipogenic progenitors promotes myofibres atrophy and fibrosis

(2018) Luca Madaro et al.   NATURE CELL BIOLOGY

TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD

(2018) Ching-Chieh Chou et al.   NATURE NEUROSCIENCE

Cell death cascade and molecular therapy in ADAR2-deficient motor neurons of ALS

(2018) Takenari Yamashita et al.   NEUROSCIENCE RESEARCH

STAT3 associates with vacuolar H+-ATPase and regulates cytosolic and lysosomal pH

(2018) Bin Liu et al.   CELL RESEARCH

OUP accepted manuscript

(2018)   RHEUMATOLOGY

Dysregulation of Astrocytic HMGB1 Signaling in Amyotrophic Lateral Sclerosis

(2018) Liliana Brambilla et al.   Frontiers in Neuroscience

Cerebrospinal Fluid Inflammatory Cytokine Aberrations in Alzheimer's Disease, Parkinson's Disease and Amyotrophic Lateral Sclerosis: A Systematic Review and Meta-Analysis

(2018) Xi Chen et al.   Frontiers in Immunology

Differential activation of neuronal and glial STAT3 in the spinal cord of the SOD1 G93A mouse model of amyotrophic lateral sclerosis

(2017) Tomohiro Ohgomori et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Reactive Astrocytes: Production, Function, and Therapeutic Potential

(2017) Shane A. Liddelow et al.   IMMUNITY

The IL-1β phenomena in neuroinflammatory diseases

(2017) Andrew S. Mendiola et al.   JOURNAL OF NEURAL TRANSMISSION

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

The role of mitochondria in amyotrophic lateral sclerosis

(2017) Emma F. Smith et al.   NEUROSCIENCE LETTERS

Stress-induced dynamic regulation of mitochondrial STAT3 and its association with cyclophilin D reduce mitochondrial ROS production

(2017) Jeremy A. Meier et al.   Science Signaling

Characterization of Gene Expression Phenotype in Amyotrophic Lateral Sclerosis Monocytes

(2017) Weihua Zhao et al.   JAMA Neurology

Stress-induced dynamic regulation of mitochondrial STAT3 and its association with cyclophilin D reduce mitochondrial ROS production

(2017) Jeremy A. Meier et al.   Science Signaling

Can you teach old drugs new tricks?

(2016) Nicola Nosengo   NATURE

Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis

(2016) SungWon Song et al.   NATURE MEDICINE

The complex STATes of astrocyte reactivity: How are they controlled by the JAK–STAT3 pathway?

(2016) Kelly Ceyzériat et al.   NEUROSCIENCE

Mitochondrial GRIM-19 as a potential therapeutic target for STAT3-dependent carcinogenesis of gastric cancer

(2016) Yi Huang et al.   Oncotarget

Enhanced Transcriptional Activity and Mitochondrial Localization of STAT3 Co-induce Axon Regrowth in the Adult Central Nervous System

(2016) Xueting Luo et al.   Cell Reports

Gene-specific mitochondria dysfunctions in human TARDBP and C9ORF72 fibroblasts

(2016) Elisa Onesto et al.   Acta Neuropathologica Communications

A STAT3-mediated metabolic switch is involved in tumour transformation and STAT3 addiction

(2016) Marco Demaria et al.   Aging-US

Aberrant association of misfolded SOD1 with Na+/K+ATPase-α3 impairs its activity and contributes to motor neuron vulnerability in ALS

(2015) Céline Ruegsegger et al.   ACTA NEUROPATHOLOGICA

The role of STAT3 in autophagy

(2015) Liangkun You et al.   Autophagy

JAK/STAT pathway regulation of GABA A receptor expression after differing severities of experimental TBI

(2015) Daniel J. Raible et al.   EXPERIMENTAL NEUROLOGY

Dynamic Mitochondrial Localisation of STAT3 in the Cellular Adipogenesis Model 3T3-L1

(2015) Adam H. Kramer et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Mitochondrial dysfunction in blood cells from amyotrophic lateral sclerosis patients

(2015) Johannes K. Ehinger et al.   JOURNAL OF NEUROLOGY

IL-6 Inhibits Starvation-induced Autophagy via the STAT3/Bcl-2 Signaling Pathway

(2015) Beibei Qin et al.   Scientific Reports

STAT3-Mediated Metabolic Reprograming in Cellular Transformation and Implications for Drug Resistance

(2015) Valeria Poli et al.   Frontiers in Oncology

Rapamycin and Chloroquine: The In Vitro and In Vivo Effects of Autophagy-Modifying Drugs Show Promising Results in Valosin Containing Protein Multisystem Proteinopathy

(2015) Angèle Nalbandian et al.   PLoS One

Inflammation Induces TDP-43 Mislocalization and Aggregation

(2015) Ana Sofia Correia et al.   PLoS One

Molecular Pathways: Interleukin-15 Signaling in Health and in Cancer

(2014) A. Mishra et al.   CLINICAL CANCER RESEARCH

PERK-Dependent Activation of JAK1 and STAT3 Contributes to Endoplasmic Reticulum Stress-Induced Inflammation

(2014) G. P. Meares et al.   MOLECULAR AND CELLULAR BIOLOGY

Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models

(2014) Sami J Barmada et al.   Nature Chemical Biology

Activating germline mutations in STAT3 cause early-onset multi-organ autoimmune disease

(2014) Sarah E Flanagan et al.   NATURE GENETICS

Autophagy regulates amyotrophic lateral sclerosis-linked fused in sarcoma-positive stress granules in neurons

(2014) Hyun-Hee Ryu et al.   NEUROBIOLOGY OF AGING

Axonal Transport of TDP-43 mRNA Granules Is Impaired by ALS-Causing Mutations

(2014) Nael H. Alami et al.   NEURON

Mitochondrial-Targeted Curcuminoids: A Strategy to Enhance Bioavailability and Anticancer Efficacy of Curcumin

(2014) Cheruku Apoorva Reddy et al.   PLoS One

STAT3 Activities and Energy Metabolism: Dangerous Liaisons

(2014) Annalisa Camporeale et al.   Cancers

Energy-sensitive regulation of Na+/K+-ATPase by Janus kinase 2

(2013) Shefalee K. Bhavsar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Rapamycin increases survival in ALS mice lacking mature lymphocytes

(2013) Kim A Staats et al.   Molecular Neurodegeneration

Cognitive changes predict functional decline in ALS: A population-based longitudinal study

(2013) M. Elamin et al.   NEUROLOGY

Neuroprotection through Excitability and mTOR Required in ALS Motoneurons to Delay Disease and Extend Survival

(2013) Smita Saxena et al.   NEURON

STAT3 and HIF1α cooperatively activate HIF1 target genes in MDA-MB-231 and RCC4 cells

(2013) M R Pawlus et al.   ONCOGENE

An Imbalance Between Excitatory and Inhibitory Neurotransmitters in Amyotrophic Lateral Sclerosis Revealed by Use of 3-T Proton Magnetic Resonance Spectroscopy

(2013) Bradley R. Foerster et al.   JAMA Neurology

JAK/STAT3 pathway inhibition blocks skeletal muscle wasting downstream of IL-6 and in experimental cancer cachexia

(2012) Andrea Bonetto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The Import of the Transcription Factor STAT3 into Mitochondria Depends on GRIM-19, a Component of the Electron Transport Chain

(2012) Prasad Tammineni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs

(2012) Clotilde Lagier-Tourenne et al.   NATURE NEUROSCIENCE

Mitochondrial complex I deficiency and ATP/ADP ratio in lymphocytes of amyotrophic lateral sclerosis patients

(2012) Parisa Ghiasi et al.   NEUROLOGICAL RESEARCH

Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43

(2012) I.-F. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endogenous regulatory T lymphocytes ameliorate amyotrophic lateral sclerosis in mice and correlate with disease progression in patients with amyotrophic lateral sclerosis

(2011) David R. Beers et al.   BRAIN

IL-6 induces lipolysis and mitochondrial dysfunction, but does not affect insulin-mediated glucose transport in 3T3-L1 adipocytes

(2011) Chenbo Ji et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Mechanical Ventilation–induced Diaphragm Disuse in Humans Triggers Autophagy

(2010) Sabah N. A. Hussain et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Mitochondrial Respiratory Chain Dysfunction in Muscle From Patients With Amyotrophic Lateral Sclerosis

(2010) Veronica Crugnola et al.   ARCHIVES OF NEUROLOGY

A role for motoneuron subtype–selective ER stress in disease manifestations of FALS mice

(2009) Smita Saxena et al.   NATURE NEUROSCIENCE

Activation of Signal Transducer and Activator of Transcription-3 in the Spinal Cord of Sporadic Amyotrophic Lateral Sclerosis Patients

(2009) Noriyuki Shibata et al.   Neurodegenerative Diseases

Activation of STAT3 and inhibitory effects of pioglitazone on STAT3 activity in a mouse model of SOD1-mutated amyotrophic lateral sclerosis

(2009) Noriyuki Shibata et al.   NEUROPATHOLOGY

Signal Transducer and Activator of Transcription 3 Is Required for Hypoxia-Inducible Factor-1  RNA Expression in Both Tumor Cells and Tumor-Associated Myeloid Cells

(2008) G. Niu et al.   MOLECULAR CANCER RESEARCH