The AI-Assisted Identification and Clinical Efficacy of Baricitinib in the Treatment of COVID-19
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The AI-Assisted Identification and Clinical Efficacy of Baricitinib in the Treatment of COVID-19
Authors
Keywords
-
Journal
Vaccines
Volume 10, Issue 6, Pages 951
Publisher
MDPI AG
Online
2022-06-20
DOI
10.3390/vaccines10060951
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Janus kinase-targeting therapies in rheumatology: a mechanisms-based approach
- (2022) Yoshiya Tanaka et al. Nature Reviews Rheumatology
- Efficacy and safety of baricitinib plus standard of care for the treatment of critically ill hospitalised adults with COVID-19 on invasive mechanical ventilation or extracorporeal membrane oxygenation: an exploratory, randomised, placebo-controlled trial
- (2022) E Wesley Ely et al. Lancet Respiratory Medicine
- Oral Nirmatrelvir/Ritonavir Therapy for COVID-19: The Dawn in the Dark?
- (2022) Yuan-Pin Hung et al. Antibiotics-Basel
- The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies
- (2022) Jérémy Manry et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Baricitinib versus dexamethasone for adults hospitalised with COVID-19 (ACTT-4): a randomised, double-blind, double placebo-controlled trial
- (2022) Cameron R Wolfe et al. Lancet Respiratory Medicine
- JAK-inhibitor and type I interferon ability to produce favorable clinical outcomes in COVID-19 patients: a systematic review and meta-analysis
- (2021) Lucas Walz et al. BMC INFECTIOUS DISEASES
- SARS-CoV-2 infects cells following viral entry via clathrin-mediated endocytosis
- (2021) Armin Bayati et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Short linear motif candidates in the cell entry system used by SARS-CoV-2 and their potential therapeutic implications
- (2021) Bálint Mészáros et al. Science Signaling
- COVID ‐19: immunopathology, pathophysiological mechanisms, and treatment options
- (2021) Larissa E. Eijk et al. JOURNAL OF PATHOLOGY
- Tocilizumab in Hospitalized Patients with Severe Covid-19 Pneumonia
- (2021) Ivan O. Rosas et al. NEW ENGLAND JOURNAL OF MEDICINE
- Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19
- (2021) NEW ENGLAND JOURNAL OF MEDICINE
- Sarilumab in patients admitted to hospital with severe or critical COVID-19: a randomised, double-blind, placebo-controlled, phase 3 trial
- (2021) François-Xavier Lescure et al. Lancet Respiratory Medicine
- Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
- (2021) Obbina Abani et al. LANCET
- JAK-inhibitors for coronavirus disease-2019 (COVID-19): a meta-analysis
- (2021) Chong-xiang Chen et al. LEUKEMIA
- Effect of Canakinumab vs Placebo on Survival Without Invasive Mechanical Ventilation in Patients Hospitalized With Severe COVID-19
- (2021) Roberto Caricchio et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19
- (2021) et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Baricitinib reduces 30‐day mortality in older adults with moderate‐to‐severe COVID ‐19 pneumonia
- (2021) Pedro Abizanda et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial
- (2021) Evdoxia Kyriazopoulou et al. NATURE MEDICINE
- Calming the cytokine storm in COVID-19
- (2021) Randy Q. Cron et al. NATURE MEDICINE
- Tofacitinib in Patients Hospitalized with Covid-19 Pneumonia
- (2021) Patrícia O. Guimarães et al. NEW ENGLAND JOURNAL OF MEDICINE
- Tofacitinib reduces mortality in coronavirus disease 2019 Tofacitinib in COVID-19
- (2021) Roman Maslennikov et al. PULMONARY PHARMACOLOGY & THERAPEUTICS
- Effectiveness of Tocilizumab in Patients Hospitalized With COVID-19
- (2021) Xavier Mariette et al. JAMA Internal Medicine
- Expert-Augmented Computational Drug Repurposing Identified Baricitinib as a Treatment for COVID-19
- (2021) Daniel P. Smith et al. Frontiers in Pharmacology
- Baricitinib: the first immunomodulatory treatment to reduce COVID-19 mortality in a placebo-controlled trial
- (2021) Andre C Kalil et al. Lancet Respiratory Medicine
- Efficacy and safety of baricitinib for the treatment of hospitalised adults with COVID-19 (COV-BARRIER): a randomised, double-blind, parallel-group, placebo-controlled phase 3 trial
- (2021) Vincent C Marconi et al. Lancet Respiratory Medicine
- Senescent T cells: a potential biomarker and target for cancer therapy
- (2021) Jie Zhang et al. EBioMedicine
- T Cell Immunosenescence in Aging, Obesity, and Cardiovascular Disease
- (2021) Kohsuke Shirakawa et al. Cells
- Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths
- (2021) Paul Bastard et al. Science Immunology
- COVID-19: Inflammatory Profile
- (2021) Yuhang Wang et al. Annual Review of Medicine
- Tocilizumab and remdesivir in hospitalized patients with severe COVID-19 pneumonia: a randomized clinical trial
- (2021) Ivan O. Rosas et al. INTENSIVE CARE MEDICINE
- How Immunosenescence and Inflammaging May Contribute to Hyperinflammatory Syndrome in COVID-19
- (2021) Ludmila Müller et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Clinical efficacy and adverse events of baricitinib treatment for coronavirus disease‐2019 (COVID‐19): A systematic review and meta‐analysis
- (2021) Zhiwei Lin et al. JOURNAL OF MEDICAL VIROLOGY
- Why we still need drugs for COVID ‐19 and can't just rely on vaccines
- (2021) Bruce W. S. Robinson et al. RESPIROLOGY
- Soluble Urokinase Plasminogen Activator Receptor (suPAR) as a Biomarker of Systemic Chronic Inflammation
- (2021) Line Jee Hartmann Rasmussen et al. Frontiers in Immunology
- Role of Senescence and Aging in SARS-CoV-2 Infection and COVID-19 Disease
- (2021) Seodhna M. Lynch et al. Cells
- SARS-CoV-2 uses metabotropic glutamate receptor subtype 2 as an internalization factor to infect cells
- (2021) Jinliang Wang et al. Cell Discovery
- Effect of anakinra on mortality in patients with COVID-19: a systematic review and patient-level meta-analysis
- (2021) Evdoxia Kyriazopoulou et al. Lancet Rheumatology
- Coronavirus infections and immune responses
- (2020) Geng Li et al. JOURNAL OF MEDICAL VIROLOGY
- Baricitinib as potential treatment for 2019-nCoV acute respiratory disease
- (2020) Peter Richardson et al. LANCET
- COVID-19: combining antiviral and anti-inflammatory treatments
- (2020) Justin Stebbing et al. LANCET INFECTIOUS DISEASES
- Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19
- (2020) Daniel Blanco-Melo et al. CELL
- Mechanism of baricitinib supports artificial intelligence‐predicted testing in COVID‐19 patients
- (2020) Justin Stebbing et al. EMBO Molecular Medicine
- Case-Fatality Rate and Characteristics of Patients Dying in Relation to COVID-19 in Italy
- (2020) Graziano Onder et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Ruxolitinib in treatment of severe coronavirus disease 2019 (COVID-19): A multicenter, single-blind, randomized controlled trial
- (2020) Yang Cao et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Remdesivir for the Treatment of Covid-19 — Preliminary Report
- (2020) John H. Beigel et al. NEW ENGLAND JOURNAL OF MEDICINE
- The CD153 vaccine is a senotherapeutic option for preventing the accumulation of senescent T cells in mice
- (2020) Shota Yoshida et al. Nature Communications
- The Immune Response Against Human Cytomegalovirus Links Cellular to Systemic Senescence
- (2020) John J. Heath et al. Cells
- Use of Baricitinib in Patients with Moderate and Severe COVID-19
- (2020) Boghuma K Titanji et al. CLINICAL INFECTIOUS DISEASES
- Presence of Genetic Variants Among Young Men With Severe COVID-19
- (2020) Caspar I. van der Made et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Beneficial impact of Baricitinib in COVID-19 moderate pneumonia; multicentre study
- (2020) Fabrizio Cantini et al. JOURNAL OF INFECTION
- Dexamethasone in Hospitalized Patients with Covid-19 — Preliminary Report
- (2020) NEW ENGLAND JOURNAL OF MEDICINE
- Quantum Dot-Conjugated SARS-CoV-2 Spike Pseudo-Virions Enable Tracking of Angiotensin Converting Enzyme 2 Binding and Endocytosis
- (2020) Kirill Gorshkov et al. ACS Nano
- Efficacy of baricitinib in treating rheumatoid arthritis: Modulatory effects on fibrotic and inflammatory biomarkers in a real-life setting
- (2020) Miriana d'Alessandro et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19
- (2020) et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Soluble Urokinase Receptor (SuPAR) in COVID-19–Related AKI
- (2020) Tariq U. Azam et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Efficacy of Tocilizumab in Patients Hospitalized with Covid-19
- (2020) John H. Stone et al. NEW ENGLAND JOURNAL OF MEDICINE
- Baricitinib improves respiratory function in patients treated with corticosteroids for SARS-CoV-2 pneumonia: an observational cohort study
- (2020) Jose Luis Rodriguez-Garcia et al. RHEUMATOLOGY
- Neuropilin-1 is a host factor for SARS-CoV-2 infection
- (2020) James L. Daly et al. SCIENCE
- Preclinical validation of therapeutic targets predicted by tensor factorization on heterogeneous graphs
- (2020) Saee Paliwal et al. Scientific Reports
- A living WHO guideline on drugs for covid-19
- (2020) François Lamontagne et al. BMJ-British Medical Journal
- Effect of Tocilizumab vs Usual Care in Adults Hospitalized With COVID-19 and Moderate or Severe Pneumonia
- (2020) Olivier Hermine et al. JAMA Internal Medicine
- Immunosuppressive Drugs and COVID-19: A Review
- (2020) Tessa S. Schoot et al. Frontiers in Pharmacology
- Targeting Inflammation and Immunosenescence to Improve Vaccine Responses in the Elderly
- (2020) Branca Pereira et al. Frontiers in Immunology
- Genetic mechanisms of critical illness in Covid-19
- (2020) Erola Pairo-Castineira et al. NATURE
- Repurposed Antiviral Drugs for Covid-19 — Interim WHO Solidarity Trial Results
- (2020) NEW ENGLAND JOURNAL OF MEDICINE
- Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19
- (2020) Andre C. Kalil et al. NEW ENGLAND JOURNAL OF MEDICINE
- Tocilizumab in Patients Hospitalized with Covid-19 Pneumonia
- (2020) Carlos Salama et al. NEW ENGLAND JOURNAL OF MEDICINE
- Efficacy and harms of remdesivir for the treatment of COVID-19: A systematic review and meta-analysis
- (2020) Alejandro Piscoya et al. PLoS One
- Corticosteroids for Patients With Coronavirus Disease 2019 (COVID-19) With Different Disease Severity: A Meta-Analysis of Randomized Clinical Trials
- (2020) Laura Pasin et al. JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA
- Immunosenescence and human vaccine immune responses
- (2019) Stephen N. Crooke et al. Immunity & Ageing
- Feasibility and biological rationale of repurposing sunitinib and erlotinib for dengue treatment
- (2018) Szu-Yuan Pu et al. ANTIVIRAL RESEARCH
- Increased neutrophil extracellular trap formation promotes thrombosis in myeloproliferative neoplasms
- (2018) Ofir Wolach et al. Science Translational Medicine
- Viral journeys on the intracellular highways
- (2018) Makeda Robinson et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Early events during human coronavirus OC43 entry to the cell
- (2018) Katarzyna Owczarek et al. Scientific Reports
- The Role of Pulmonary and Systemic Immunosenescence in Acute Lung Injury
- (2018) Christina Brandenberger et al. Aging and Disease
- Anticancer kinase inhibitors impair intracellular viral trafficking and exert broad-spectrum antiviral effects
- (2017) Elena Bekerman et al. JOURNAL OF CLINICAL INVESTIGATION
- Obesity accelerates T cell senescence in murine visceral adipose tissue
- (2016) Kohsuke Shirakawa et al. JOURNAL OF CLINICAL INVESTIGATION
- Unusual CD4+CD28−T Cells and Their Pathogenic Role in Chronic Inflammatory Disorders
- (2016) Ga Hye Lee et al. Immune Network
- AP-2-Associated Protein Kinase 1 and Cyclin G-Associated Kinase Regulate Hepatitis C Virus Entry and Are Potential Drug Targets
- (2015) Gregory Neveu et al. JOURNAL OF VIROLOGY
- Virus entry at a glance
- (2013) Y. Yamauchi et al. JOURNAL OF CELL SCIENCE
- The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression
- (2010) Jean-Philippe Coppé et al. Annual Review of Pathology-Mechanisms of Disease
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now