Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis
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Title
Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis
Authors
Keywords
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Journal
NATURE MEDICINE
Volume 22, Issue 4, Pages 397-403
Publisher
Springer Nature
Online
2016-03-01
DOI
10.1038/nm.4052
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Note: Only part of the references are listed.- Improving Single Injection CSF Delivery of AAV9-mediated Gene Therapy for SMA: A Dose–response Study in Mice and Nonhuman Primates
- (2015) Kathrin Meyer et al. MOLECULAR THERAPY
- Marinesco-Sjögren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS
- (2015) Audrey Filézac de L'Etang et al. NATURE NEUROSCIENCE
- Macrophage Migration Inhibitory Factor as a Chaperone Inhibiting Accumulation of Misfolded SOD1
- (2015) Adrian Israelson et al. NEURON
- Glial cells in amyotrophic lateral sclerosis
- (2014) T. Philips et al. EXPERIMENTAL NEUROLOGY
- Defining the therapeutic window in a severe animal model of spinal muscular atrophy
- (2014) K. L. Robbins et al. HUMAN MOLECULAR GENETICS
- Synapse elimination and learning rules co-regulated by MHC class I H2-Db
- (2014) Hanmi Lee et al. NATURE
- Necroptosis Drives Motor Neuron Death in Models of Both Sporadic and Familial ALS
- (2014) Diane B. Re et al. NEURON
- Microglia Induce Motor Neuron Death via the Classical NF-κB Pathway in Amyotrophic Lateral Sclerosis
- (2014) Ashley E. Frakes et al. NEURON
- Transcriptomic indices of fast and slow disease progression in two mouse models of amyotrophic lateral sclerosis
- (2013) Giovanni Nardo et al. BRAIN
- Lesion HLA-F expression is irrelevant to prognosis for patients with gastric cancer
- (2013) Jian-Gang Zhang et al. HUMAN IMMUNOLOGY
- HLA-F and MHC Class I Open Conformers Are Ligands for NK Cell Ig-like Receptors
- (2013) J. P. Goodridge et al. JOURNAL OF IMMUNOLOGY
- Clinical–pathological implication of human leukocyte antigen-F–positive gastric adenocarcinoma
- (2013) Sumiya Ishigami et al. JOURNAL OF SURGICAL RESEARCH
- Therapeutic AAV9-mediated Suppression of Mutant SOD1 Slows Disease Progression and Extends Survival in Models of Inherited ALS
- (2013) Kevin D Foust et al. MOLECULAR THERAPY
- Emerging roles of astrocytes in neural circuit development
- (2013) Laura E. Clarke et al. NATURE REVIEWS NEUROSCIENCE
- Capsid Serotype and Timing of Injection Determines AAV Transduction in the Neonatal Mice Brain
- (2013) Paramita Chakrabarty et al. PLoS One
- Direct conversion of patient fibroblasts demonstrates non-cell autonomous toxicity of astrocytes to motor neurons in familial and sporadic ALS
- (2013) K. Meyer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human LilrB2 Is a -Amyloid Receptor and Its Murine Homolog PirB Regulates Synaptic Plasticity in an Alzheimer's Model
- (2013) T. Kim et al. SCIENCE
- Beta-2 microglobulin is important for disease progression in a murine model for amyotrophic lateral sclerosis
- (2013) Kim A. Staats et al. Frontiers in Cellular Neuroscience
- Aging brain microenvironment decreases hippocampal neurogenesis through Wnt-mediated survivin signaling
- (2012) Carlos J. Miranda et al. AGING CELL
- Endoplasmic reticulum stress and the ER mitochondria calcium cycle in amyotrophic lateral sclerosis
- (2012) Janin Lautenschlaeger et al. Amyotrophic Lateral Sclerosis
- Neuroimmune crosstalk in the central nervous system and its significance for neurological diseases
- (2012) Li Tian et al. Journal of Neuroinflammation
- Viral delivery of miR-196a ameliorates the SBMA phenotype via the silencing of CELF2
- (2012) Yu Miyazaki et al. NATURE MEDICINE
- The Expression Pattern of Classical MHC Class I Molecules in the Development of Mouse Central Nervous System
- (2012) Jiane Liu et al. NEUROCHEMICAL RESEARCH
- Rapid and Efficient Generation of Functional Motor Neurons From Human Pluripotent Stem Cells Using Gene Delivered Transcription Factor Codes
- (2011) Mark E Hester et al. MOLECULAR THERAPY
- Systemic Gene Delivery in Large Species for Targeting Spinal Cord, Brain, and Peripheral Tissues for Pediatric Disorders
- (2011) Adam K Bevan et al. MOLECULAR THERAPY
- Astrocytes from familial and sporadic ALS patients are toxic to motor neurons
- (2011) Amanda M Haidet-Phillips et al. NATURE BIOTECHNOLOGY
- Clinical diagnosis and management of amyotrophic lateral sclerosis
- (2011) Orla Hardiman et al. Nature Reviews Neurology
- Phenotypically aberrant astrocytes that promote motoneuron damage in a model of inherited amyotrophic lateral sclerosis
- (2011) P. Diaz-Amarilla et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Guidelines for preclinical animal research in ALS/MND: A consensus meeting
- (2010) Albert C. Ludolph et al. Amyotrophic Lateral Sclerosis
- Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS
- (2010) Daryl A Bosco et al. NATURE NEUROSCIENCE
- MHC class I molecules are present both pre- and postsynaptically in the visual cortex during postnatal development and in adulthood
- (2010) L. A. Needleman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MHC class I modulates NMDA receptor function and AMPA receptor trafficking
- (2010) L. Fourgeaud et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Non–cell autonomous toxicity in neurodegenerative disorders: ALS and beyond
- (2009) Hristelina Ilieva et al. JOURNAL OF CELL BIOLOGY
- Major histocompatability complex class I expression and glial reaction influence spinal motoneuron synaptic plasticity during the course of experimental autoimmune encephalomyelitis
- (2009) C.M. Freria et al. JOURNAL OF COMPARATIVE NEUROLOGY
- Classical Major Histocompatibility Complex Class I Molecules in Motoneurons: New Actors at the Neuromuscular Junction
- (2009) S. Thams et al. JOURNAL OF NEUROSCIENCE
- A role for motoneuron subtype–selective ER stress in disease manifestations of FALS mice
- (2009) Smita Saxena et al. NATURE NEUROSCIENCE
- Immune Proteins in Brain Development and Synaptic Plasticity
- (2009) Lisa M. Boulanger NEURON
- Two Factor Reprogramming of Human Neural Stem Cells into Pluripotency
- (2009) Mark E. Hester et al. PLoS One
- H2-Kb and H2-Db regulate cerebellar long-term depression and limit motor learning
- (2009) M. J. McConnell et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6
- (2009) C. Vance et al. SCIENCE
- Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis
- (2009) T. J. Kwiatkowski et al. SCIENCE
- Non-Cell-Autonomous Effect of Human SOD1G37R Astrocytes on Motor Neurons Derived from Human Embryonic Stem Cells
- (2008) Maria C.N. Marchetto et al. Cell Stem Cell
- ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1
- (2008) H. Nishitoh et al. GENES & DEVELOPMENT
- TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis
- (2008) Vivianna M Van Deerlin et al. LANCET NEUROLOGY
- Delivery of AAV-IGF-1 to the CNS Extends Survival in ALS Mice Through Modification of Aberrant Glial Cell Activity
- (2008) James C Dodge et al. MOLECULAR THERAPY
- Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors
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- T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS
- (2008) I. M. Chiu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
- (2008) J. Sreedharan et al. SCIENCE
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