Protective Effect of Olive Oil Microconstituents in Atherosclerosis: Emphasis on PAF Implicated Atherosclerosis Theory

Long-term secondary prevention of cardiovascular disease with a Mediterranean diet and a low-fat diet (CORDIOPREV): a randomised controlled trial

(2022) Javier Delgado-Lista et al.   LANCET

Is there an interplay between the SARS‐CoV ‐2 spike protein and Platelet‐Activating factor?

(2022) Smaragdi Antonopoulou et al.   BIOFACTORS

Olive Oil Phenolics and Platelets—From Molecular Mechanisms to Human Studies

(2022) Maria Efthymia Katsa et al.   Reviews in Cardiovascular Medicine

Platelet Activating Factor (PAF): A Mediator of Inflammation

(2022) Julia E. M. Upton et al.   BIOFACTORS

Overview of OxLDL and Its Impact on Cardiovascular Health: Focus on Atherosclerosis

(2021) Anastasia V. Poznyak et al.   Frontiers in Pharmacology

Consumption of Enriched Yogurt with PAF Inhibitors from Olive Pomace Affects the Major Enzymes of PAF Metabolism: A Randomized, Double Blind, Three Arm Trial

(2021) Maria Detopoulou et al.   Biomolecules

Gamma-tocopherol, a major form of vitamin E in diets: Insights into antioxidant and anti-inflammatory effects, mechanisms, and roles in disease management

(2021) Qing Jiang et al.   FREE RADICAL BIOLOGY AND MEDICINE

The association between dietary patterns and the novel inflammatory markers platelet-activating factor and lipoprotein-associated phospholipase A2: a systematic review

(2021) Carolyn J English et al.   NUTRITION REVIEWS

Effects of Dietary Patterns on Biomarkers of Inflammation and Immune Responses: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

(2021) Liselot Koelman et al.   Advances in Nutrition

Association of Dietary Phytosterols with Cardiovascular Disease Biomarkers in Humans

(2020) Ramandeep Kaur et al.   LIPIDS

A review on management of cardiovascular diseases by olive polyphenols

(2020) Arshad Mehmood et al.   Food Science & Nutrition

Bioactive Compounds and Quality of Extra Virgin Olive Oil

(2020) Cecilia Jimenez-Lopez et al.   Foods

Total and Sustainable Valorisation of Olive Pomace Using a Fractionation Approach

(2020) Tânia B. Ribeiro et al.   Applied Sciences-Basel

Effects of Virgin Olive Oils Differing in Their Bioactive Compound Contents on Biomarkers of Oxidative Stress and Inflammation in Healthy Adults: A Randomized Double-Blind Controlled Trial

(2019) Estefania Sanchez-Rodriguez et al.   Nutrients

An overview of the pharmacology of olive oil and its active ingredients

(2019) Francesco Visioli et al.   BRITISH JOURNAL OF PHARMACOLOGY

Olive polyphenol reduces the collagen-elicited release of phosphorylated HSP27 from human platelets

(2019) Daisuke Mizutani et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Phospholipidome of extra virgin olive oil: Development of a solid phase extraction protocol followed by liquid chromatography–high resolution mass spectrometry for its software-assisted identification

(2019) Michela Antonelli et al.   FOOD CHEMISTRY

Circulating Vitamin E Levels and Risk of Coronary Artery Disease and Myocardial Infarction: A Mendelian Randomization Study

(2019) Tao Wang et al.   Nutrients

Virgin Olive Oil and Health: Summary of the III International Conference on Virgin Olive Oil and Health Consensus Report, JAEN (Spain) 2018

(2019) Gaforio et al.   Nutrients

Oleuropein, a Bioactive Compound from Olea europaea L., as a Potential Preventive and Therapeutic Agent in Non-Communicable Diseases

(2019) Chiara Nediani et al.   Antioxidants

Forty Years Since the Structural Elucidation of Platelet-Activating Factor (PAF): Historical, Current, and Future Research Perspectives

(2019) Ronan Lordan et al.   MOLECULES

Oleuropein, a component of extra virgin olive oil, lowers postprandial glycaemia in healthy subjects

(2018) Roberto Carnevale et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

The effect of high-polyphenol extra virgin olive oil on cardiovascular risk factors: a systematic review and meta-analysis

(2018) Elena S George et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Extra-Virgin Olive Oil with Natural Phenolic Content Exerts an Anti-Inflammatory Effect in Adipose Tissue and Attenuates the Severity of Atherosclerotic Lesions in Ldlr −/−.Leiden Mice

(2018) Amparo Luque-Sierra et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Effects of Virgin Olive Oils Differing in Their Bioactive Compound Contents on Metabolic Syndrome and Endothelial Functional Risk Biomarkers in Healthy Adults: A Randomized Double-Blind Controlled Trial

(2018) Estefania Sanchez-Rodriguez et al.   Nutrients

Mediterranean diet and platelet-activating factor; a systematic review

(2018) Tzortzis Nomikos et al.   CLINICAL BIOCHEMISTRY

Ginkgolide B ameliorates oxidized low-density lipoprotein-induced endothelial dysfunction via modulating Lectin-like ox-LDL-receptor-1 and NADPH oxidase 4 expression and inflammatory cascades

(2018) Zhanbin Feng et al.   PHYTOTHERAPY RESEARCH

Oleuropein prevents the development of experimental autoimmune myocarditis in rats

(2017) Jia-Ying Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Ginkgolide B Suppresses TLR4-Mediated Inflammatory Response by Inhibiting the Phosphorylation of JAK2/STAT3 and p38 MAPK in High Glucose-Treated HUVECs

(2017) Kun Chen et al.   Oxidative Medicine and Cellular Longevity

Antioxidant Effects of a Hydroxytyrosol-Based Pharmaceutical Formulation on Body Composition, Metabolic State, and Gene Expression: A Randomized Double-Blinded, Placebo-Controlled Crossover Trial

(2017) Carmela Colica et al.   Oxidative Medicine and Cellular Longevity

Hydroxytyrosol supplementation increases vitamin C levels in vivo . A human volunteer trial

(2017) Eduardo Lopez-Huertas et al.   Redox Biology

Impact of phenolic-rich olive leaf extract on blood pressure, plasma lipids and inflammatory markers: a randomised controlled trial

(2016) Stacey Lockyer et al.   EUROPEAN JOURNAL OF NUTRITION

Hydroxytyrosol in functional hydroxytyrosol-enriched biscuits is highly bioavailable and decreases oxidised low density lipoprotein levels in humans

(2016) Raquel Mateos et al.   FOOD CHEMISTRY

Secoiridoids delivered as olive leaf extract induce acute improvements in human vascular function and reduction of an inflammatory cytokine: a randomised, double-blind, placebo-controlled, cross-over trial

(2015) Stacey Lockyer et al.   BRITISH JOURNAL OF NUTRITION

Serum lipid profile and inflammatory markers in the aorta of cholesterol-fed rats supplemented with extra virgin olive oil, sunflower oils and oil-products

(2015) Ageliki I. Katsarou et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

One-week administration of hydroxytyrosol to humans does not activate Phase II enzymes

(2015) Maria Carmen Crespo et al.   PHARMACOLOGICAL RESEARCH

Platelet Activating Factor (PAF) biosynthesis is inhibited by phenolic compounds in U-937 cells under inflammatory conditions

(2015) Ioanna C. Vlachogianni et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Phenolic content of extra virgin olive oil is essential to restore endothelial dysfunction but not to prevent vascular inflammation in atherosclerotic lesions of Apo E deficient mice

(2015) Carmen Claro et al.   Journal of Functional Foods

The relation of diet with PAF and its metabolic enzymes in healthy volunteers

(2014) P. Detopoulou et al.   EUROPEAN JOURNAL OF NUTRITION

Monounsaturated fatty acids, olive oil and health status: a systematic review and meta-analysis of cohort studies

(2014) Lukas Schwingshackl et al.   Lipids in Health and Disease

Hydroxytyrosyl alkyl ether derivatives inhibit platelet activation after oral administration to rats

(2013) Javier Muñoz-Marín et al.   FOOD AND CHEMICAL TOXICOLOGY

Bioactive Properties of the Main Triterpenes Found in Olives, Virgin Olive Oil, and Leaves of Olea europaea

(2013) Cristina Sánchez-Quesada et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Olive (Olea europaea L.) Leaf Polyphenols Improve Insulin Sensitivity in Middle-Aged Overweight Men: A Randomized, Placebo-Controlled, Crossover Trial

(2013) Martin de Bock et al.   PLoS One

Activation of PAF-receptor induces regulatory dendritic cells through PGE2 and IL-10

(2013) Marianna M. Koga et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Use of antiplatelet agents in sepsis: A glimpse into the future

(2013) Karolina Akinosoglou et al.   THROMBOSIS RESEARCH

Antiplatelet effect of new lipophilic hydroxytyrosol alkyl ether derivatives in human blood

(2012) J. J. Reyes et al.   EUROPEAN JOURNAL OF NUTRITION

The “Mevalonate hypothesis”: a cholesterol-independent alternative for the etiology of atherosclerosis

(2012) Hiskias G Keizer   Lipids in Health and Disease

Efficacy of bioactive compounds from extra virgin olive oil to modulate atherosclerosis development

(2012) José M. Lou-Bonafonte et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Fish polar lipids retard atherosclerosis in rabbits by down-regulating PAF biosynthesis and up-regulating PAF catabolism

(2011) Constantina Nasopoulou et al.   Lipids in Health and Disease

Biological Activities of Phenolic Compounds Present in Virgin Olive Oil

(2010) Sara Cicerale et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Olive (Olea europaea) leaf extract effective in patients with stage-1 hypertension: Comparison with Captopril

(2010) Endang Susalit et al.   PHYTOMEDICINE

Olive Phenolics Increase Glutathione Levels in Healthy Volunteers

(2009) Francesco Visioli et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Atherosclerosis regression study in rabbits upon olive pomace polar lipid extract administration

(2009) N. Tsantila et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Virgin olive oil polyphenol hydroxytyrosol acetate inhibits in vitro platelet aggregation in human whole blood: comparison with hydroxytyrosol and acetylsalicylic acid

(2008) José Antonio González Correa et al.   BRITISH JOURNAL OF NUTRITION

Biology of Platelet-activating Factor Acetylhydrolase (PAF-AH, Lipoprotein Associated Phospholipase A2)

(2008) Diana M. Stafforini   CARDIOVASCULAR DRUGS AND THERAPY

Effects of Hydroxytyrosol and Hydroxytyrosol Acetate Administration to Rats on Platelet Function Compared to Acetylsalicylic Acid

(2008) José Antonio González-Correa et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Identification of a Novel Noninflammatory Biosynthetic Pathway of Platelet-activating Factor

(2008) Takeshi Harayama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BIOACTIVE POLAR LIPIDS IN OLIVE OIL, POMACE AND WASTE BYPRODUCTS

(2008) HARALABOS C. KARANTONIS et al.   JOURNAL OF FOOD BIOCHEMISTRY

Vascular Effects of Diet Supplementation With Plant Sterols

(2008) Oliver Weingärtner et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Squalene in a sex-dependent manner modulates atherosclerotic lesion which correlates with hepatic fat content in apoE-knockout male mice

(2007) Natalia Guillén et al.   ATHEROSCLEROSIS