Towards a better understanding of diabetes mellitus using organoid models
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Title
Towards a better understanding of diabetes mellitus using organoid models
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Journal
Nature Reviews Endocrinology
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2023-01-21
DOI
10.1038/s41574-022-00797-x
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Note: Only part of the references are listed.- Cell maturation: Hallmarks, triggers, and manipulation
- (2022) Juan R. Alvarez-Dominguez et al. CELL
- A diabetic milieu increases ACE2 expression and cellular susceptibility to SARS-CoV-2 infections in human kidney organoids and patient cells
- (2022) Elena Garreta et al. Cell Metabolism
- Genetics of Type 2 Diabetes: Implications from Large-Scale Studies
- (2022) Natalie DeForest et al. Current Diabetes Reports
- Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells
- (2022) Diego Balboa et al. NATURE BIOTECHNOLOGY
- An HNF1α truncation associated with maturity-onset diabetes of the young impairs pancreatic progenitor differentiation by antagonizing HNF1β function
- (2022) Ana-Maria Cujba et al. Cell Reports
- Aberrant Splicing of INS Impairs Beta-Cell Differentiation and Proliferation by ER Stress in the Isogenic iPSC Model of Neonatal Diabetes
- (2022) Alexandra V. Panova et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Exocrine-Endocrine Crosstalk: The Influence of Pancreatic Cellular Communications on Organ Growth, Function and Disease
- (2022) Danielle L. Overton et al. Frontiers in Endocrinology
- Reduced calcium levels and accumulation of abnormal insulin granules in stem cell models of HNF1A deficiency
- (2022) Bryan J. González et al. Communications Biology
- Human liver model systems in a dish
- (2021) Wendy L. Thompson et al. DEVELOPMENT GROWTH & DIFFERENTIATION
- Loss of MANF causes childhood onset syndromic diabetes due to increased endoplasmic reticulum stress
- (2021) Hossam Montaser et al. DIABETES
- SIX2 and SIX3 coordinately regulate functional maturity and fate of human pancreatic β cells
- (2021) Romina J. Bevacqua et al. GENES & DEVELOPMENT
- Current understanding of the molecular and cellular pathology of diabetic retinopathy
- (2021) David A. Antonetti et al. Nature Reviews Endocrinology
- Modeling Maturity Onset Diabetes of the Young in Pluripotent Stem Cells: Challenges and Achievements
- (2021) Carmel Braverman-Gross et al. Frontiers in Endocrinology
- Organoid microphysiological system preserves pancreatic islet function within 3D matrix
- (2021) S. N. Patel et al. Science Advances
- Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids
- (2021) Ary Marsee et al. Cell Stem Cell
- Commitment and oncogene-induced plasticity of human stem cell-derived pancreatic acinar and ductal organoids
- (2021) Ling Huang et al. Cell Stem Cell
- Vascular deficiencies in renal organoids and ex vivo kidney organogenesis
- (2021) Anne R. Ryan et al. DEVELOPMENTAL BIOLOGY
- Interpreting type 1 diabetes risk with genetics and single-cell epigenomics
- (2021) Joshua Chiou et al. NATURE
- Human Pluripotent Stem Cells to Model Islet Defects in Diabetes
- (2021) Diego Balboa et al. Frontiers in Endocrinology
- Modeling Type 1 Diabetes Using Pluripotent Stem Cell Technology
- (2021) Kriti Joshi et al. Frontiers in Endocrinology
- Microvessels support engraftment and functionality of human islets and hESC-derived pancreatic progenitors in diabetes models
- (2021) Yasaman Aghazadeh et al. Cell Stem Cell
- The next generation of endothelial differentiation: Tissue-specific ECs
- (2021) Jane Nguyen et al. Cell Stem Cell
- Pathogenesis, diagnosis and clinical management of diabetic sensorimotor peripheral neuropathy
- (2021) Gordon Sloan et al. Nature Reviews Endocrinology
- Strategies for durable β cell replacement in type 1 diabetes
- (2021) Todd M. Brusko et al. SCIENCE
- A 3D system to model human pancreas development and its reference single-cell transcriptome atlas identify signaling pathways required for progenitor expansion
- (2021) Carla A. Gonçalves et al. Nature Communications
- Human sensorimotor organoids derived from healthy and amyotrophic lateral sclerosis stem cells form neuromuscular junctions
- (2021) João D. Pereira et al. Nature Communications
- Treatment of type 2 diabetes: challenges, hopes, and anticipated successes
- (2021) Michael A Nauck et al. Lancet Diabetes & Endocrinology
- Understanding the Long-Lasting Effects of Fetal Nutrient Restriction versus Exposure to an Obesogenic Diet on Islet-Cell Mass and Function
- (2021) Stephanie E. O’Hara et al. Metabolites
- Advanced models of human skeletal muscle differentiation, development and disease: Three-dimensional cultures, organoids and beyond
- (2021) Salma Jalal et al. CURRENT OPINION IN CELL BIOLOGY
- Mutations and variants of ONECUT1 in diabetes
- (2021) Anne Philippi et al. NATURE MEDICINE
- Microengineered Multi‐Organoid System from hiPSCs to Recapitulate Human Liver‐Islet Axis in Normal and Type 2 Diabetes
- (2021) Tingting Tao et al. Advanced Science
- Modeling human T1D-associated autoimmune processes
- (2021) Mohsen Khosravi-Maharlooei et al. Molecular Metabolism
- Use of Induced Pluripotent Stem Cells to Build Isogenic Systems and Investigate Type 1 Diabetes
- (2021) Lucas H. Armitage et al. Frontiers in Endocrinology
- Towards organoid culture without Matrigel
- (2021) Mark T. Kozlowski et al. Communications Biology
- Long-Term Expansion of Pancreatic Islet Organoids from Resident Procr+ Progenitors
- (2020) Daisong Wang et al. CELL
- A Nutrient-Sensing Transition at Birth Triggers Glucose-Responsive Insulin Secretion
- (2020) Aharon Helman et al. Cell Metabolism
- Diabetes through a 3D lens: organoid models
- (2020) Anastasia Tsakmaki et al. DIABETOLOGIA
- Gene-edited human stem cell–derived β cells from a patient with monogenic diabetes reverse preexisting diabetes in mice
- (2020) Kristina G. Maxwell et al. Science Translational Medicine
- Fat-on-a-Chip models for research and discovery in obesity and its metabolic co-morbidities
- (2020) Michelle McCarthy et al. TISSUE ENGINEERING PART B-REVIEWS
- Glucose Response by Stem Cell-Derived β Cells In Vitro Is Inhibited by a Bottleneck in Glycolysis
- (2020) Jeffrey C. Davis et al. Cell Reports
- A Droplet Microfluidic System to Fabricate Hybrid Capsules Enabling Stem Cell Organoid Engineering
- (2020) Haitao Liu et al. Advanced Science
- Microwell-based pancreas-on-chip model enhances genes expression and functionality of rat islets of Langerhans
- (2020) Amal Essaouiba et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Hair-bearing human skin generated entirely from pluripotent stem cells
- (2020) Jiyoon Lee et al. NATURE
- Emerging routes to the generation of functional β-cells for diabetes mellitus cell therapy
- (2020) Gopika G. Nair et al. Nature Reviews Endocrinology
- Maternal exposure to Δ9-tetrahydrocannabinol impairs female offspring glucose homeostasis and endocrine pancreatic development in the rat
- (2020) Ryan Gillies et al. REPRODUCTIVE TOXICOLOGY
- Labeling and Characterization of Human GLP-1-Secreting L-cells in Primary Ileal Organoid Culture
- (2020) Deborah A. Goldspink et al. Cell Reports
- Modeling Type 1 Diabetes In Vitro Using Human Pluripotent Stem Cells
- (2020) Nayara C. Leite et al. Cell Reports
- Integrated human pseudoislet system and microfluidic platform demonstrate differences in GPCR signaling in islet cells
- (2020) John T. Walker et al. JCI Insight
- Advances Toward Engineering Functionally Mature Human Pluripotent Stem Cell-Derived β Cells
- (2020) Leonardo Velazco-Cruz et al. Frontiers in Bioengineering and Biotechnology
- Maternal low-protein diet on the last week of pregnancy contributes to insulin resistance and β-cell dysfunction in the mouse offspring
- (2020) Emilyn U. Alejandro et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- A Cell-Autonomous Signature of Dysregulated Protein Phosphorylation Underlies Muscle Insulin Resistance in Type 2 Diabetes
- (2020) Thiago M. Batista et al. Cell Metabolism
- hPSC-derived organoids: models of human development and disease
- (2020) Tristan Frum et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis
- (2020) Brisa Palikuqi et al. NATURE
- Single-Cell Transcriptome Profiling Reveals β Cell Maturation in Stem Cell-Derived Islets after Transplantation
- (2020) Punn Augsornworawat et al. Cell Reports
- Neonatal Diabetes Mellitus
- (2020) Jacques Beltrand et al. Frontiers in Pediatrics
- Construction of a Novel In Vitro Atherosclerotic Model from Geometry‐Tunable Artery Equivalents Engineered via In‐Bath Coaxial Cell Printing
- (2020) Ge Gao et al. ADVANCED FUNCTIONAL MATERIALS
- Modeling different types of diabetes using human pluripotent stem cells
- (2020) Essam M. Abdelalim CELLULAR AND MOLECULAR LIFE SCIENCES
- Pancreas-on-a-Chip Technology for Transplantation Applications
- (2020) Shadab Abadpour et al. Current Diabetes Reports
- Retinal organoids: a window into human retinal development
- (2020) Michelle O'Hara-Wright et al. DEVELOPMENT
- Monogenic Diabetes: From Genetic Insights to Population-Based Precision in Care. Reflections From a Diabetes Care Editors’ Expert Forum
- (2020) Matthew C. Riddle et al. DIABETES CARE
- Generation of immune cell containing adipose organoids for in vitro analysis of immune metabolism
- (2020) Jacqueline Taylor et al. Scientific Reports
- Human blood vessel organoids as a model of diabetic vasculopathy
- (2019) Reiner A. Wimmer et al. NATURE
- Adipogenesis and metabolic health
- (2019) Alexandra L. Ghaben et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Acquisition of Dynamic Function in Human Stem Cell-Derived β Cells
- (2019) Leonardo Velazco-Cruz et al. Stem Cell Reports
- Applications of stem cells and bioprinting for potential treatment of diabetes
- (2019) Shweta Anil Kumar et al. World Journal of Stem Cells
- Point mutations in the PDX1 transactivation domain impair human β-cell development and function
- (2019) Xianming Wang et al. Molecular Metabolism
- Prenatal Malnutrition-Induced Epigenetic Dysregulation as a Risk Factor for Type 2 Diabetes
- (2019) Alexander Vaiserman et al. International Journal of Genomics
- Offspring of Mice Exposed to a Low-Protein Diet in Utero Demonstrate Changes in mTOR Signaling in Pancreatic Islets of Langerhans, Associated with Altered Glucagon and Insulin Expression and a Lower β-Cell Mass
- (2019) Renee King et al. Nutrients
- Renal reabsorption in 3D vascularized proximal tubule models
- (2019) Neil Y. C. Lin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Flow-enhanced vascularization and maturation of kidney organoids in vitro
- (2019) Kimberly A. Homan et al. NATURE METHODS
- Fine tuning the extracellular environment accelerates the derivation of kidney organoids from human pluripotent stem cells
- (2019) Elena Garreta et al. NATURE MATERIALS
- Recapitulating endocrine cell clustering in culture promotes maturation of human stem-cell-derived β cells
- (2019) Gopika G. Nair et al. NATURE CELL BIOLOGY
- Lgr5+ stem/progenitor cells reside at the apex of a heterogeneous embryonic hepatoblast pool
- (2019) Nicole Prior et al. DEVELOPMENT
- Charting cellular identity during human in vitro β-cell differentiation
- (2019) Adrian Veres et al. NATURE
- Guide to the Assessment of Mature Liver Gene Expression in Stem Cell-Derived Hepatocytes.
- (2019) Mihaela Zabulica et al. STEM CELLS AND DEVELOPMENT
- 3-D Culture and Endothelial Cells Improve Maturity of Human Pluripotent Stem Cell-Derived Hepatocytes
- (2019) Hamisha Ardalani et al. Acta Biomaterialia
- Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids
- (2019) Rie Ouchi et al. Cell Metabolism
- Consequences of being overweight or obese during pregnancy on diabetes in the offspring: a record linkage study in Aberdeen, Scotland
- (2019) Marius Lahti-Pulkkinen et al. DIABETOLOGIA
- Liver organoids: from basic research to therapeutic applications
- (2019) Nicole Prior et al. GUT
- Non-invasive marker-independent high content analysis of a microphysiological human pancreas-on-a-chip model
- (2019) Aline Zbinden et al. MATRIX BIOLOGY
- Expression of mutant mRNA and protein in pancreatic cells derived from MODY3- iPS cells
- (2019) Shigeharu G. Yabe et al. PLoS One
- Patient-derived pancreas-on-a-chip to model cystic fibrosis-related disorders
- (2019) Kyu Shik Mun et al. Nature Communications
- Human adipose stromal-vascular fraction self-organizes to form vascularized adipose tissue in 3D cultures
- (2019) Sandra Muller et al. Scientific Reports
- A hydrogel platform for in vitro three dimensional assembly of human stem cell-derived islet cells and endothelial cells
- (2019) Punn Augsornworawat et al. Acta Biomaterialia
- Modeling Monogenic Diabetes using Human ESCs Reveals Developmental and Metabolic Deficiencies Caused by Mutations in HNF1A
- (2019) Fabian L. Cardenas-Diaz et al. Cell Stem Cell
- A Comprehensive Structure-Function Study of Neurogenin3 Disease-Causing Alleles during Human Pancreas and Intestinal Organoid Development
- (2019) Xinghao Zhang et al. DEVELOPMENTAL CELL
- Induced pluripotent stem cell macrophages present antigen to proinsulin-specific T cell receptors from donor-matched islet-infiltrating T cells in type 1 diabetes
- (2019) Kriti Joshi et al. DIABETOLOGIA
- Developmental overnutrition and obesity and type 2 diabetes in offspring
- (2019) Wei Perng et al. DIABETOLOGIA
- Human kidney organoids: progress and remaining challenges
- (2019) Ryuichi Nishinakamura Nature Reviews Nephrology
- Merging organoid and organ-on-a-chip technology to generate complex multi-layer tissue models in a human retina-on-a-chip platform
- (2019) Kevin Achberger et al. eLife
- Early-life Programming of Type 2 Diabetes Mellitus: Understanding the Association between Epigenetics/Genetics and Environmental Factors
- (2019) Fatma Zehra Kadayifci et al. CURRENT GENOMICS
- Exposure to maternal obesity programs sex differences in pancreatic islets of the offspring in mice
- (2019) Lisa M. Nicholas et al. DIABETOLOGIA
- Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification
- (2019) Michele A. La Merrill et al. Nature Reviews Endocrinology
- Microvessel network formation and interactions with pancreatic islets in 3D chip cultures
- (2019) Mia Hauge Rambøl et al. TISSUE ENGINEERING PART A
- Effects of Nutrient Intake during Pregnancy and Lactation on the Endocrine Pancreas of the Offspring
- (2019) Valentine Suzanne Moullé et al. Nutrients
- In vivo–mimicking microfluidic perfusion culture of pancreatic islet spheroids
- (2019) Yesl Jun et al. Science Advances
- Controlled Heterotypic Pseudo-Islet Assembly of Human β-Cells and Human Umbilical Vein Endothelial Cells Using Magnetic Levitation
- (2019) Max Urbanczyk et al. TISSUE ENGINEERING PART A
- Analysis of Differentiation Protocols Defines a Common Pancreatic Progenitor Molecular Signature and Guides Refinement of Endocrine Differentiation
- (2019) Agata Wesolowska-Andersen et al. Stem Cell Reports
- Establishment of a high-resolution 3D modeling system for studying pancreatic epithelial cell biology in vitro
- (2019) Mostafa Bakhti et al. Molecular Metabolism
- 3D heterogeneous islet organoid generation from human embryonic stem cells using a novel engineered hydrogel platform
- (2018) Joseph Candiello et al. BIOMATERIALS
- Intestinal organoids for modelling intestinal development and disease
- (2018) Kathryn L. Fair et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Derivation and molecular characterization of pancreatic differentiated MODY1-iPSCs
- (2018) Carmel Braverman-Gross et al. Stem Cell Research
- Simulated Cholinergic Reinnervation of β (INS-1) Cells: Antidiabetic Utility of Heterotypic Pseudoislets Containing β Cell and Cholinergic Cell
- (2018) Ao Jiao et al. International Journal of Endocrinology
- Discovery of a drug candidate for GLIS3-associated diabetes
- (2018) Sadaf Amin et al. Nature Communications
- Scaffold-free generation of uniform adipose spheroids for metabolism research and drug discovery
- (2018) Aloysius J. Klingelhutz et al. Scientific Reports
- Three-Dimensional Human iPSC-Derived Artificial Skeletal Muscles Model Muscular Dystrophies and Enable Multilineage Tissue Engineering
- (2018) Sara Martina Maffioletti et al. Cell Reports
- Self-Condensation Culture Enables Vascularization of Tissue Fragments for Efficient Therapeutic Transplantation
- (2018) Yoshinobu Takahashi et al. Cell Reports
- Heterogeneity of SOX9 and HNF1β in Pancreatic Ducts Is Dynamic
- (2018) Habib Rezanejad et al. Stem Cell Reports
- Expansion of Adult Human Pancreatic Tissue Yields Organoids Harboring Progenitor Cells with Endocrine Differentiation Potential
- (2018) Cindy J.M. Loomans et al. Stem Cell Reports
- The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates
- (2018) Violeta Georgieva Tsonkova et al. Molecular Metabolism
- 3-D physiomimetic extracellular matrix hydrogels provide a supportive microenvironment for rodent and human islet culture
- (2018) K. Jiang et al. BIOMATERIALS
- Interconnected Microphysiological Systems for Quantitative Biology and Pharmacology Studies
- (2018) Collin D. Edington et al. Scientific Reports
- Deconstructing the principles of ductal network formation in the pancreas
- (2018) Svend Bertel Dahl-Jensen et al. PLOS BIOLOGY
- Stem-cell based organ-on-a-chip models for diabetes research
- (2018) Julia Rogal et al. ADVANCED DRUG DELIVERY REVIEWS
- Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
- (2018) Huili Hu et al. CELL
- Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture
- (2018) Weng Chuan Peng et al. CELL
- Generation of functional human pancreatic organoids by transplants of embryonic stem cell derivatives in a 3D-printed tissue trapper
- (2018) Anahita Soltanian et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Pancreatic Progenitors: There and Back Again
- (2018) Juan Domínguez-Bendala et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Insulin mutations impair beta-cell development in a patient-derived iPSC model of neonatal diabetes
- (2018) Diego Balboa et al. eLife
- β Cell Replacement after Gene Editing of a Neonatal Diabetes-Causing Mutation at the Insulin Locus
- (2018) Shuangyu Ma et al. Stem Cell Reports
- Multilineage communication regulates human liver bud development from pluripotency
- (2017) J. Gray Camp et al. NATURE
- Modelling diabetic nephropathy in mice
- (2017) Kengo Azushima et al. Nature Reviews Nephrology
- The molecular and morphogenetic basis of pancreas organogenesis
- (2017) Hjalte List Larsen et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Development of Islet Organoids from H9 Human Embryonic Stem Cells in Biomimetic 3D Scaffolds
- (2017) Weiwei Wang et al. STEM CELLS AND DEVELOPMENT
- Microphysiological Analysis Platform of Pancreatic Islet β-Cell Spheroids
- (2017) Sang Hun Lee et al. Advanced Healthcare Materials
- An Activating STAT3 Mutation Causes Neonatal Diabetes through Premature Induction of Pancreatic Differentiation
- (2017) Jonna Saarimäki-Vire et al. Cell Reports
- Long-Term Adult Feline Liver Organoid Cultures for Disease Modeling of Hepatic Steatosis
- (2017) Hedwig S. Kruitwagen et al. Stem Cell Reports
- Probing the missing mature β-cell proteomic landscape in differentiating patient iPSC-derived cells
- (2017) Heidrun Vethe et al. Scientific Reports
- Organotypic pancreatoids with native mesenchyme develop Insulin producing endocrine cells
- (2017) Marissa A. Scavuzzo et al. Scientific Reports
- Functional coupling of human pancreatic islets and liver spheroids on-a-chip: Towards a novel human ex vivo type 2 diabetes model
- (2017) Sophie Bauer et al. Scientific Reports
- Maternal high-fat diet promotes onset of diabetes in rat offspring
- (2016) Takeshi Ohta et al. ANIMAL SCIENCE JOURNAL
- Design and demonstration of a pumpless 14 compartment microphysiological system
- (2016) Paula G. Miller et al. BIOTECHNOLOGY AND BIOENGINEERING
- Genome Editing of Lineage Determinants in Human Pluripotent Stem Cells Reveals Mechanisms of Pancreatic Development and Diabetes
- (2016) Zengrong Zhu et al. Cell Stem Cell
- Maternal Exposure to Bisphenol-A During Pregnancy Increases Pancreatic β-Cell Growth During Early Life in Male Mice Offspring
- (2016) Marta García-Arévalo et al. ENDOCRINOLOGY
- Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling
- (2016) Meike Hohwieler et al. GUT
- High-fat diet enhances stemness and tumorigenicity of intestinal progenitors
- (2016) Semir Beyaz et al. NATURE
- Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation
- (2016) Laura Broutier et al. Nature Protocols
- Maternal protein restriction during gestation impairs female offspring pancreas development in the rat
- (2016) Lizbeth Calzada et al. NUTRITION RESEARCH
- Myotubes derived from human-induced pluripotent stem cells mirror in vivo insulin resistance
- (2016) Salvatore Iovino et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human pancreatic beta-like cells converted from fibroblasts
- (2016) Saiyong Zhu et al. Nature Communications
- Generation of stem cell-derived β-cells from patients with type 1 diabetes
- (2016) Jeffrey R. Millman et al. Nature Communications
- A simple, reliable method for high-throughput screening for diabetes drugs using 3D β-cell spheroids
- (2016) Jesal Amin et al. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
- Early Developmental Perturbations in a Human Stem Cell Model of MODY5/HNF1B Pancreatic Hypoplasia
- (2016) Adrian Kee Keong Teo et al. Stem Cell Reports
- Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver
- (2015) Meritxell Huch et al. CELL
- Vascularized and Complex Organ Buds from Diverse Tissues via Mesenchymal Cell-Driven Condensation
- (2015) Takanori Takebe et al. Cell Stem Cell
- Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro
- (2015) H. A. Russ et al. EMBO JOURNAL
- Bisphenol-A Treatment During Pregnancy in Mice: A New Window of Susceptibility for the Development of Diabetes in Mothers Later in Life
- (2015) Paloma Alonso-Magdalena et al. ENDOCRINOLOGY
- Maternal exposure to air pollution and type 1 diabetes – Accounting for genetic factors
- (2015) Ebba Malmqvist et al. ENVIRONMENTAL RESEARCH
- Controlled aggregation of primary human pancreatic islet cells leads to glucose-responsive pseudoislets comparable to native islets
- (2015) Janneke Hilderink et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis
- (2015) Minoru Takasato et al. NATURE
- Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell– and patient-derived tumor organoids
- (2015) Ling Huang et al. NATURE MEDICINE
- Cell aggregation optimizes the differentiation of human ESCs and iPSCs into pancreatic bud-like progenitor cells
- (2015) Taro Toyoda et al. Stem Cell Research
- Ex Vivo Expansion and Differentiation of Human and Mouse Fetal Pancreatic Progenitors Are Modulated by Epidermal Growth Factor
- (2015) Paola Bonfanti et al. STEM CELLS AND DEVELOPMENT
- Intestinal organoids for assessing nutrient transport, sensing and incretin secretion
- (2015) Tamara Zietek et al. Scientific Reports
- Generation of Functional Human Pancreatic β Cells In Vitro
- (2014) Felicia W. Pagliuca et al. CELL
- Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells
- (2014) Alireza Rezania et al. NATURE BIOTECHNOLOGY
- Generation of three-dimensional retinal tissue with functional photoreceptors from human iPSCs
- (2014) Xiufeng Zhong et al. Nature Communications
- Disease Modeling and Phenotypic Drug Screening for Diabetic Cardiomyopathy using Human Induced Pluripotent Stem Cells
- (2014) Faye M. Drawnel et al. Cell Reports
- Artificial three-dimensional niches deconstruct pancreas development in vitro
- (2013) C. Greggio et al. DEVELOPMENT
- -Cell Dysfunction Due to Increased ER Stress in a Stem Cell Model of Wolfram Syndrome
- (2013) L. Shang et al. DIABETES
- Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis
- (2013) Meritxell Huch et al. EMBO JOURNAL
- Vascularized and functional human liver from an iPSC-derived organ bud transplant
- (2013) Takanori Takebe et al. NATURE
- Maternal Obesity during the Preconception and Early Life Periods Alters Pancreatic Development in Early and Adult Life in Male Mouse Offspring
- (2013) Isabele Bringhenti et al. PLoS One
- Reconstituting pancreas development from purified progenitor cells reveals genes essential for islet differentiation
- (2013) T. Sugiyama et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transmaternal Bisphenol A Exposure Accelerates Diabetes Type 1 Development in NOD Mice
- (2013) Johanna Bodin et al. TOXICOLOGICAL SCIENCES
- Self-Formation of Optic Cups and Storable Stratified Neural Retina from Human ESCs
- (2012) Tokushige Nakano et al. Cell Stem Cell
- Intrapatient Variations in Type 1 Diabetes-specific iPS Cell Differentiation Into Insulin-producing Cells
- (2012) Tayaramma Thatava et al. MOLECULAR THERAPY
- Maternal malnutrition programs the endocrine pancreas in progeny
- (2011) Brigitte Reusens et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Stage-specific signaling through TGF family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells
- (2011) M. C. Nostro et al. DEVELOPMENT
- The functional and molecular characterisation of human embryonic stem cell-derived insulin-positive cells compared with adult pancreatic beta cells
- (2011) C. L. Basford et al. DIABETOLOGIA
- Generation of Glucose-Responsive Functional Islets with a Three-Dimensional Structure from Mouse Fetal Pancreatic Cells and iPS Cells In Vitro
- (2011) Hiroki Saito et al. PLoS One
- Maternal diet and aging alter the epigenetic control of a promoter-enhancer interaction at the Hnf4a gene in rat pancreatic islets
- (2011) I. Sandovici et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Kidney Spheroids Recapitulate Tubular Organoids Leading to Enhanced Tubulogenic Potency of Human Kidney-Derived Cells
- (2011) Ella Buzhor et al. TISSUE ENGINEERING PART A
- Incorporation of endothelial progenitor cells into mosaic pseudoislets
- (2011) Daniella Penko et al. Islets
- Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro
- (2010) Jason R. Spence et al. NATURE
- Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
- (2009) Toshiro Sato et al. NATURE
- Genetics of Type 1A Diabetes
- (2009) Patrick Concannon et al. NEW ENGLAND JOURNAL OF MEDICINE
- Generation of pluripotent stem cells from patients with type 1 diabetes
- (2009) R. Maehr et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Three-Dimensional Differentiation of Embryonic Stem Cells into Islet-like Insulin-Producing Clusters
- (2009) Xiuli Wang et al. TISSUE ENGINEERING PART A
- Microfluidic device for multimodal characterization of pancreatic islets
- (2008) Javeed Shaikh Mohammed et al. LAB ON A CHIP
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