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Title
Discovery of a drug candidate for GLIS3-associated diabetes
Authors
Keywords
-
Journal
Nature Communications
Volume 9, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-07-05
DOI
10.1038/s41467-018-04918-x
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- The Spatiotemporal Pattern of Glis3 Expression Indicates a Regulatory Function in Bipotent and Endocrine Progenitors during Early Pancreatic Development and in Beta, PP and Ductal Cells
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- (2015) H. A. Russ et al. EMBO JOURNAL
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- (2014) Felicia W. Pagliuca et al. CELL
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- (2014) Christiane Winkler et al. DIABETOLOGIA
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- The Krüppel-Like Protein Gli-Similar 3 (Glis3) Functions as a Key Regulator of Insulin Transcription
- (2013) Gary T. ZeRuth et al. MOLECULAR ENDOCRINOLOGY
- Improving prediction of type 1 diabetes by testing non-HLA genetic variants in addition to HLA markers
- (2013) Andrea K Steck et al. PEDIATRIC DIABETES
- GLIS3, a Susceptibility Gene for Type 1 and Type 2 Diabetes, Modulates Pancreatic Beta Cell Apoptosis via Regulation of a Splice Variant of the BH3-Only Protein Bim
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- Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians
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- Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
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- (2007) Lorea Bueno et al. EUROPEAN JOURNAL OF CANCER
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