The functional and molecular characterisation of human embryonic stem cell-derived insulin-positive cells compared with adult pancreatic beta cells

The Adult Mouse and Human Pancreas Contain Rare Multipotent Stem Cells that Express Insulin

(2011) Simon R. Smukler et al.   Cell Stem Cell

Stage-specific signaling through TGF  family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells

(2011) M. C. Nostro et al.   DEVELOPMENT

Cell-surface markers for the isolation of pancreatic cell types derived from human embryonic stem cells

(2011) Olivia G Kelly et al.   NATURE BIOTECHNOLOGY

Inconsistent formation and nonfunction of insulin-positive cells from pancreatic endoderm derived from human embryonic stem cells in athymic nude rats

(2010) Aleksey V. Matveyenko et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

NKX6.1 Promotes PDX-1-Induced Liver to Pancreatic β-Cells Reprogramming

(2010) Shiraz Gefen-Halevi et al.   Cellular Reprogramming

Production of Functional Glucagon-Secreting  -Cells From Human Embryonic Stem Cells

(2010) A. Rezania et al.   DIABETES

Voltage-dependent K+ channels are positive regulators of alpha cell action potential generation and glucagon secretion in mice and humans

(2010) A. F. Spigelman et al.   DIABETOLOGIA

Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells

(2010) C. Aguayo-Mazzucato et al.   DIABETOLOGIA

Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion

(2010) N. Wijesekara et al.   DIABETOLOGIA

Noggin, Retinoids, and Fibroblast Growth Factor Regulate Hepatic or Pancreatic Fate of Human Embryonic Stem Cells

(2010) Josué Kunjom Mfopou et al.   GASTROENTEROLOGY

Identification of Markers for Newly Formed β-Cells in the Perinatal Period: A Time of Recognized β-Cell Immaturity

(2010) Tandy Aye et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss

(2010) Fabrizio Thorel et al.   NATURE

The insulin secretory granule as a signaling hub

(2010) Jakob Suckale et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Exocytosis of Insulin

(2009) Aldo Rozzo et al.   Annals of the New York Academy of Sciences

Islet-1 is Required for the Maturation, Proliferation, and Survival of the Endocrine Pancreas

(2009) A. Du et al.   DIABETES

Molecular and Metabolic Evidence for Mitochondrial Defects Associated With  -Cell Dysfunction in a Mouse Model of Type 2 Diabetes

(2009) H. Lu et al.   DIABETES

Insulin Storage and Glucose Homeostasis in Mice Null for the Granule Zinc Transporter ZnT8 and Studies of the Type 2 Diabetes-Associated Variants

(2009) T. J. Nicolson et al.   DIABETES

Characterization of Erg K+Channels in α- and β-Cells of Mouse and Human Islets

(2009) Alexandre B. Hardy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of biphasic insulin-granule exocytosis - roles of the cytoskeleton, small GTPases and SNARE proteins

(2009) Z. Wang et al.   JOURNAL OF CELL SCIENCE

A small molecule that directs differentiation of human ESCs into the pancreatic lineage

(2009) Shuibing Chen et al.   Nature Chemical Biology

Derivation of insulin-producing cells from human embryonic stem cells

(2009) Dennis Van Hoof et al.   Stem Cell Research

Pancreatic islet transplantation

(2009) Maria Corrêa-Giannella et al.   Diabetology & Metabolic Syndrome

Generation of pancreatic islet cells from human embryonic stem cells

(2009) DongHui Zhang et al.   Science in China. Series C, Life sciences / Chinese Academy of Sciences

Biphasic Ngn3 expression in the developing pancreas

(2008) Alethia Villasenor et al.   DEVELOPMENTAL DYNAMICS

Transcription factor expression in the developing human fetal endocrine pancreas

(2008) B. M. Lyttle et al.   DIABETOLOGIA

Genes controlling pancreas ontogeny

(2008) Claire Bonal et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Differential intracellular transport and binding of verotoxin 1 and verotoxin 2 to globotriaosylceramide‐containing lipid assemblies

(2008) Patty Tam et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo

(2008) Evert Kroon et al.   NATURE BIOTECHNOLOGY

UCP2 is highly expressed in pancreatic  -cells and influences secretion and survival

(2008) J. Diao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA