Role of the cGAS–STING pathway in systemic and organ-specific diseases
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Role of the cGAS–STING pathway in systemic and organ-specific diseases
Authors
Keywords
-
Journal
Nature Reviews Nephrology
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-06-22
DOI
10.1038/s41581-022-00589-6
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Chemical and Biomolecular Strategies for STING Pathway Activation in Cancer Immunotherapy
- (2022) Kyle M. Garland et al. CHEMICAL REVIEWS
- The cGAS–STING pathway drives type I IFN immunopathology in COVID-19
- (2022) Jeremy Di Domizio et al. NATURE
- The volume-regulated anion channel LRRC8C suppresses T cell function by regulating cyclic dinucleotide transport and STING–p53 signaling
- (2022) Axel R. Concepcion et al. NATURE IMMUNOLOGY
- Association of metabolic dysfunction-associated fatty liver disease with kidney disease
- (2022) Ting-Yao Wang et al. Nature Reviews Nephrology
- Type I interferon–related kidney disorders
- (2022) Lorenzo Lodi et al. KIDNEY INTERNATIONAL
- A non-canonical cGAS–STING–PERK pathway facilitates the translational program critical for senescence and organ fibrosis
- (2022) Dan Zhang et al. NATURE CELL BIOLOGY
- Suppression of local type I interferon by gut microbiota–derived butyrate impairs antitumor effects of ionizing radiation
- (2021) Kaiting Yang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A Nuclear Export Signal Is Required for cGAS to Sense Cytosolic DNA
- (2021) Hong Sun et al. Cell Reports
- Lactobacillus rhamnosus GG induces cGAS/STING- dependent type I interferon and improves response to immune checkpoint blockade
- (2021) Wei Si et al. GUT
- STING-Mediated Lung Inflammation and Beyond
- (2021) Marie-Louise Frémond et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Phosphorylation and chromatin tethering prevent cGAS activation during mitosis
- (2021) Tuo Li et al. SCIENCE
- Highly Multiplexed Mass Cytometry Identifies the Immunophenotype in the Skin of Dermatomyositis
- (2021) Jay Patel et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- DNA sensor in standby mode during mitosis
- (2021) Andrea Ablasser SCIENCE
- Transferrable protection by gut microbes against STING-associated lung disease
- (2021) Derek J. Platt et al. Cell Reports
- cGAS-STING Pathway Does Not Promote Autoimmunity in Murine Models of SLE
- (2021) Mona Motwani et al. Frontiers in Immunology
- A STING antagonist modulating the interaction with STIM1 blocks ER-to-Golgi trafficking and inhibits lupus pathology
- (2021) Thaneas Prabakaran et al. EBioMedicine
- Pharmacological activation of STING blocks SARS-CoV-2 infection
- (2021) Minghua Li et al. Science Immunology
- Erythroid mitochondrial retention triggers myeloid-dependent type I interferon in human SLE
- (2021) Simone Caielli et al. CELL
- Endogenous retroviruses promote homeostatic and inflammatory responses to the microbiota
- (2021) Djalma S. Lima-Junior et al. CELL
- Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells
- (2021) Liraz Shmuel-Galia et al. IMMUNITY
- Translation stress and collided ribosomes are co-activators of cGAS
- (2021) Li Wan et al. MOLECULAR CELL
- cGAS-like receptors sense RNA and control 3′2′-cGAMP signalling in Drosophila
- (2021) Kailey M. Slavik et al. NATURE
- Two cGAS-like receptors induce antiviral immunity in Drosophila
- (2021) Andreas Holleufer et al. NATURE
- NAD+ supplementation reduces neuroinflammation and cell senescence in a transgenic mouse model of Alzheimer’s disease via cGAS–STING
- (2021) Yujun Hou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- STING inhibitors target the cyclic dinucleotide binding pocket
- (2021) Ze Hong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human SLC46A2 Is the Dominant cGAMP Importer in Extracellular cGAMP-Sensing Macrophages and Monocytes
- (2021) Anthony F. Cordova et al. ACS Central Science
- Microbiota triggers STING-type I IFN-dependent monocyte reprogramming of the tumor microenvironment
- (2021) Khiem C. Lam et al. CELL
- TBK1 recruitment to STING mediates autoinflammatory arthritis caused by defective DNA clearance
- (2021) Tong Li et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Chromatin bridges, not micronuclei, activate cGAS after drug-induced mitotic errors in human cells
- (2021) Patrick J. Flynn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Involvement of RIG-I Pathway in Neurotropic Virus-Induced Acute Flaccid Paralysis and Subsequent Spinal Motor Neuron Death
- (2021) Meenakshi Bhaskar et al. mBio
- Tau activates microglia via the PQBP1-cGAS-STING pathway to promote brain inflammation
- (2021) Meihua Jin et al. Nature Communications
- TNF leads to mtDNA release and cGAS/STING-dependent interferon responses that support inflammatory arthritis
- (2021) Joschka Willemsen et al. Cell Reports
- Connexin-Dependent Transfer of cGAMP to Phagocytes Modulates Antiviral Responses
- (2020) Geneviève Pépin et al. mBio
- Toll-like Receptors and the Control of Immunity
- (2020) Katherine A. Fitzgerald et al. CELL
- Microbiota-Induced Type I Interferons Instruct a Poised Basal State of Dendritic Cells
- (2020) Laura Schaupp et al. CELL
- Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity
- (2020) Chun Zhou et al. IMMUNITY
- Type I interferon response drives neuroinflammation and synapse loss in Alzheimer disease
- (2020) Ethan R. Roy et al. JOURNAL OF CLINICAL INVESTIGATION
- Molecular mechanisms and cellular functions of cGAS–STING signalling
- (2020) Karl-Peter Hopfner et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Hepatic gap junctions amplify alcohol liver injury by propagating cGAS-mediated IRF3 activation
- (2020) Jay Luther et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The early local and systemic Type I interferon responses to ultraviolet B light exposure are cGAS dependent
- (2020) Sladjana Skopelja-Gardner et al. Scientific Reports
- Small molecules targeting the innate immune cGAS‒STING‒TBK1 signaling pathway
- (2020) Chunyong Ding et al. Acta Pharmaceutica Sinica B
- Phosphorylation of cGAS by CDK1 impairs self-DNA sensing in mitosis
- (2020) Li Zhong et al. Cell Discovery
- Type I interferon-independent T cell impairment in a Tmem173 N153S/WT mouse model of STING associated vasculopathy with onset in infancy (SAVI)
- (2020) Hannah Siedel et al. CLINICAL IMMUNOLOGY
- Interferon-Independent Activities of Mammalian STING Mediate Antiviral Response and Tumor Immune Evasion
- (2020) Jianjun Wu et al. IMMUNITY
- Mutations in COPA lead to abnormal trafficking of STING to the Golgi and interferon signaling
- (2020) Alice Lepelley et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The commensal skin microbiota triggers type I IFN–dependent innate repair responses in injured skin
- (2020) Jeremy Di Domizio et al. NATURE IMMUNOLOGY
- Mitochondrial DNA drives abscopal responses to radiation that are inhibited by autophagy
- (2020) Takahiro Yamazaki et al. NATURE IMMUNOLOGY
- Bacterial-induced cell fusion is a danger signal triggering cGAS–STING pathway via micronuclei formation
- (2020) Joanne Wei Kay Ku et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Interferon-independent STING signaling promotes resistance to HSV-1 in vivo
- (2020) Lívia H. Yamashiro et al. Nature Communications
- Mitochondrial stress-activated cGAS-STING pathway inhibits thermogenic program and contributes to overnutrition-induced obesity in mice
- (2020) Juli Bai et al. Communications Biology
- TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS
- (2020) Chien-Hsiung Yu et al. CELL
- Role of Post-Translational Modifications of cGAS in Innate Immunity
- (2020) Yakun Wu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- STING cyclic dinucleotide sensing originated in bacteria
- (2020) Benjamin R. Morehouse et al. NATURE
- The Molecular Basis of Tight Nuclear Tethering and Inactivation of cGAS
- (2020) Baoyu Zhao et al. NATURE
- Structural basis for sequestration and autoinhibition of cGAS by chromatin
- (2020) Sebastian Michalski et al. NATURE
- Structural mechanism of cGAS inhibition by the nucleosome
- (2020) Ganesh R. Pathare et al. NATURE
- BAF restricts cGAS on nuclear DNA to prevent innate immune activation
- (2020) Baptiste Guey et al. SCIENCE
- Structural basis for the inhibition of cGAS by nucleosomes
- (2020) Tomoya Kujirai et al. SCIENCE
- Structural basis of nucleosome-dependent cGAS inhibition
- (2020) Joshua A. Boyer et al. SCIENCE
- Harnessing SLE Autoantibodies for Intracellular Delivery of Biologic Therapeutics
- (2020) Renata E. Gordon et al. TRENDS IN BIOTECHNOLOGY
- Cutibacterium acnes Infection Induces Type I Interferon Synthesis Through the cGAS-STING Pathway
- (2020) Katrin Fischer et al. Frontiers in Immunology
- STING Mediates Lupus via the Activation of Conventional Dendritic Cell Maturation and Plasmacytoid Dendritic Cell Differentiation
- (2020) Arthid Thim-uam et al. iScience
- Metastasis and immune evasion from extracellular cGAMP hydrolysis
- (2020) Jun Li et al. Cancer Discovery
- Overview of STING-Associated Vasculopathy with Onset in Infancy (SAVI) Among 21 Patients
- (2020) Marie-Louise Frémond et al. Journal of Allergy and Clinical Immunology-In Practice
- STING-mediated intestinal barrier dysfunction contributes to lethal sepsis
- (2019) Qiongyuan Hu et al. EBioMedicine
- cGAS in action: Expanding roles in immunity and inflammation
- (2019) Andrea Ablasser et al. SCIENCE
- Aspirin meets cGAS
- (2019) Keith B. Elkon Nature Reviews Rheumatology
- Acetylation Blocks cGAS Activity and Inhibits Self-DNA-Induced Autoimmunity
- (2019) Jiang Dai et al. CELL
- SLC19A1 Is an Importer of the Immunotransmitter cGAMP
- (2019) Christopher Ritchie et al. MOLECULAR CELL
- DsbA-L ameliorates high glucose induced tubular damage through maintaining MAM integrity
- (2019) Ming Yang et al. EBioMedicine
- Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression
- (2019) Lodoe Lama et al. Nature Communications
- Cyclic GMP–AMP signalling protects bacteria against viral infection
- (2019) Daniel Cohen et al. NATURE
- SLC19A1 transports immunoreactive cyclic dinucleotides
- (2019) Rutger D. Luteijn et al. NATURE
- Mitochondrial Damage and Activation of the STING Pathway Lead to Renal Inflammation and Fibrosis
- (2019) Ki Wung Chung et al. Cell Metabolism
- STING expression in monocyte-derived macrophages is associated with the progression of liver inflammation and fibrosis in patients with nonalcoholic fatty liver disease
- (2019) Xiaoxiao Wang et al. LABORATORY INVESTIGATION
- Interferon target-gene expression and epigenomic signatures in health and disease
- (2019) Franck J. Barrat et al. NATURE IMMUNOLOGY
- Stimulator of interferon genes (STING) activation exacerbates experimental colitis in mice
- (2019) Gary R. Martin et al. Scientific Reports
- Mitochondrial Damage Causes Inflammation via cGAS-STING Signaling in Acute Kidney Injury
- (2019) Hiroshi Maekawa et al. Cell Reports
- Cancer-Cell-Intrinsic cGAS Expression Mediates Tumor Immunogenicity
- (2019) Linda Schadt et al. Cell Reports
- T Cells Produce IFN-α in the TREX1 D18N Model of Lupus-like Autoimmunity
- (2019) Sean R. Simpson et al. JOURNAL OF IMMUNOLOGY
- Trial of Anifrolumab in Active Systemic Lupus Erythematosus
- (2019) Eric F. Morand et al. NEW ENGLAND JOURNAL OF MEDICINE
- Tight nuclear tethering of cGAS is essential for preventing autoreactivity
- (2019) Hannah E Volkman et al. eLife
- Apoptosis-derived membrane vesicles drive the cGAS–STING pathway and enhance type I IFN production in systemic lupus erythematosus
- (2018) Yasuhiro Kato et al. ANNALS OF THE RHEUMATIC DISEASES
- Cytosolic DNA Sensing Promotes Macrophage Transformation and Governs Myocardial Ischemic Injury
- (2018) Dian J. Cao et al. CIRCULATION
- Regulation of MAVS activation through post-translational modifications
- (2018) Bingyu Liu et al. CURRENT OPINION IN IMMUNOLOGY
- Hepatitis B virus evasion from cyclic guanosine monophosphate-adenosine monophosphate synthase sensing in human hepatocytes
- (2018) Eloi R. Verrier et al. HEPATOLOGY
- Severe combined immunodeficiency in stimulator of interferon genes (STING) V154M/wild-type mice
- (2018) Delphine Bouis et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Activation of the STING-IRF3 pathway promotes hepatocyte inflammation, apoptosis and induces metabolic disorders in nonalcoholic fatty liver disease
- (2018) J.T. Qiao et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- PUMA amplifies necroptosis signaling by activating cytosolic DNA sensors
- (2018) Dongshi Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- DNA-induced liquid phase condensation of cGAS activates innate immune signaling
- (2018) Mingjian Du et al. SCIENCE
- STING-Activating Adjuvants Elicit a Th17 Immune Response and Protect against Mycobacterium tuberculosis Infection
- (2018) Erik Van Dis et al. Cell Reports
- Review: Cell Death, Nucleic Acids, and Immunity
- (2018) Keith B. Elkon Arthritis & Rheumatology
- A novel anti-malarial drug derivative inhibits cyclic GMP-AMP synthase in Trex1 deficient mice
- (2018) Jie An et al. Arthritis & Rheumatology
- Therapeutic effects of a TBK1 kinase inhibitor in germinal center-driven, autoantibody-mediated inflammatory arthritis
- (2018) Cynthia Louis et al. Arthritis & Rheumatology
- NONO Detects the Nuclear HIV Capsid to Promote cGAS-Mediated Innate Immune Activation
- (2018) Xavier Lahaye et al. CELL
- Pink1/Parkin link inflammation, mitochondrial stress, and neurodegeneration
- (2018) Laura E. Newman et al. JOURNAL OF CELL BIOLOGY
- Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage
- (2018) Gillian Dunphy et al. MOLECULAR CELL
- Parkin and PINK1 mitigate STING-induced inflammation
- (2018) Danielle A. Sliter et al. NATURE
- Targeting STING with covalent small-molecule inhibitors
- (2018) Simone M. Haag et al. NATURE
- STING directly activates autophagy to tune the innate immune response
- (2018) Dong Liu et al. CELL DEATH AND DIFFERENTIATION
- Expression of STING Is Increased in Liver Tissues From Patients With NAFLD and Promotes Macrophage-Mediated Hepatic Inflammation and Fibrosis in Mice
- (2018) Xianjun Luo et al. GASTROENTEROLOGY
- Tumor-Derived cGAMP Triggers a STING-Mediated Interferon Response in Non-tumor Cells to Activate the NK Cell Response
- (2018) Assaf Marcus et al. IMMUNITY
- STING-mediated inflammation in Kupffer cells contributes to progression of nonalcoholic steatohepatitis
- (2018) Yongsheng Yu et al. JOURNAL OF CLINICAL INVESTIGATION
- STING-associated vasculopathy develops independently of IRF3 in mice
- (2017) James D. Warner et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The cytosolic sensor STING is required for intestinal homeostasis and control of inflammation
- (2017) M C C Canesso et al. Mucosal Immunology
- cGAS surveillance of micronuclei links genome instability to innate immunity
- (2017) Karen J. Mackenzie et al. NATURE
- Cytoplasmic chromatin triggers inflammation in senescence and cancer
- (2017) Zhixun Dou et al. NATURE
- Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence
- (2017) Selene Glück et al. NATURE CELL BIOLOGY
- IRF3 and type I interferons fuel a fatal response to myocardial infarction
- (2017) Kevin R King et al. NATURE MEDICINE
- cGAS drives noncanonical-inflammasome activation in age-related macular degeneration
- (2017) Nagaraj Kerur et al. NATURE MEDICINE
- DsbA-L prevents obesity-induced inflammation and insulin resistance by suppressing the mtDNA release-activated cGAS-cGAMP-STING pathway
- (2017) Juli Bai et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ALK is a therapeutic target for lethal sepsis
- (2017) Ling Zeng et al. Science Translational Medicine
- Evolutionary Origins of cGAS-STING Signaling
- (2017) Shally R. Margolis et al. TRENDS IN IMMUNOLOGY
- Signalling strength determines proapoptotic functions of STING
- (2017) Muhammet F. Gulen et al. Nature Communications
- Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice
- (2017) Jessica Vincent et al. Nature Communications
- STING-Dependent Signaling Underlies IL-10 Controlled Inflammatory Colitis
- (2017) Jeonghyun Ahn et al. Cell Reports
- Ultraviolet B Irradiation Causes Stimulator of Interferon Genes-Dependent Production of Protective Type I Interferon in Mouse Skin by Recruited Inflammatory Monocytes
- (2017) Clayton Sontheimer et al. Arthritis & Rheumatology
- Expression of Cyclic GMP-AMP Synthase in Patients With Systemic Lupus Erythematosus
- (2017) Jie An et al. Arthritis & Rheumatology
- The STING agonist DMXAA triggers a cooperation between T lymphocytes and myeloid cells that leads to tumor regression
- (2017) Julia M. Weiss et al. OncoImmunology
- Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay
- (2017) Justin Hall et al. PLoS One
- Dengue virus activates cGAS through the release of mitochondrial DNA
- (2017) Bo Sun et al. Scientific Reports
- Digestion of Chromatin in Apoptotic Cell Microparticles Prevents Autoimmunity
- (2016) Vanja Sisirak et al. CELL
- The cGAS-STING Defense Pathway and Its Counteraction by Viruses
- (2016) Zhe Ma et al. Cell Host & Microbe
- Endoplasmic Reticulum Stress-induced Hepatocellular Death Pathways Mediate Liver Injury and Fibrosis via Stimulator of Interferon Genes
- (2016) Arvin Iracheta-Vellve et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Oxidized mitochondrial nucleoids released by neutrophils drive type I interferon production in human lupus
- (2016) Simone Caielli et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Carcinoma–astrocyte gap junctions promote brain metastasis by cGAMP transfer
- (2016) Qing Chen et al. NATURE
- Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
- (2016) Darren J. Baker et al. NATURE
- Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease
- (2016) Christian Lood et al. NATURE MEDICINE
- Therapeutic potential of targeting TBK1 in autoimmune diseases and interferonopathies
- (2016) Maroof Hasan et al. PHARMACOLOGICAL RESEARCH
- Defects in lysosomal maturation facilitate the activation of innate sensors in systemic lupus erythematosus
- (2016) Andrew J. Monteith et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Activation of STING requires palmitoylation at the Golgi
- (2016) Kojiro Mukai et al. Nature Communications
- PQBP1 Is a Proximal Sensor of the cGAS-Dependent Innate Response to HIV-1
- (2015) Sunnie M. Yoh et al. CELL
- STING Activation by Translocation from the ER Is Associated with Infection and Autoinflammatory Disease
- (2015) Nicole Dobbs et al. Cell Host & Microbe
- Type I interferonopathies: Mendelian type I interferon up-regulation
- (2015) Yanick J Crow CURRENT OPINION IN IMMUNOLOGY
- Twenty-five years of type I interferon-based treatment: A critical analysis of its therapeutic use
- (2015) Guido Antonelli et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Cutting Edge: Inhibiting TBK1 by Compound II Ameliorates Autoimmune Disease in Mice
- (2015) Maroof Hasan et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: cGAS Is Required for Lethal Autoimmune Disease in the Trex1-Deficient Mouse Model of Aicardi–Goutières Syndrome
- (2015) Elizabeth E. Gray et al. JOURNAL OF IMMUNOLOGY
- Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA
- (2015) Anna-Maria Herzner et al. NATURE IMMUNOLOGY
- Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease
- (2015) Jessica L. Grieves et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Loss of microRNA-27b contributes to breast cancer stem cell generation by activating ENPP1
- (2015) Ryou-u Takahashi et al. Nature Communications
- Aicardi–Goutières syndrome harbours abundant systemic and brain-reactive autoantibodies
- (2014) Eloy Cuadrado et al. ANNALS OF THE RHEUMATIC DISEASES
- Crosstalk between the cGAS DNA Sensor and Beclin-1 Autophagy Protein Shapes Innate Antimicrobial Immune Responses
- (2014) Qiming Liang et al. Cell Host & Microbe
- Cutting Edge: AIM2 and Endosomal TLRs Differentially Regulate Arthritis and Autoantibody Production in DNase II–Deficient Mice
- (2014) Rebecca Baum et al. JOURNAL OF IMMUNOLOGY
- Hydrolysis of 2′3′-cGAMP by ENPP1 and design of nonhydrolyzable analogs
- (2014) Lingyin Li et al. Nature Chemical Biology
- Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling
- (2014) Gillian I Rice et al. NATURE GENETICS
- The enemy within: endogenous retroelements and autoimmune disease
- (2014) Hannah E Volkman et al. NATURE IMMUNOLOGY
- Activated STING in a Vascular and Pulmonary Syndrome
- (2014) Yin Liu et al. NEW ENGLAND JOURNAL OF MEDICINE
- DMXAA Causes Tumor Site-Specific Vascular Disruption in Murine Non-Small Cell Lung Cancer, and like the Endogenous Non-Canonical Cyclic Dinucleotide STING Agonist, 2′3′-cGAMP, Induces M2 Macrophage Repolarization
- (2014) Charlene M. Downey et al. PLoS One
- Cyclic Dinucleotides and the Innate Immune Response
- (2013) Olga Danilchanka et al. CELL
- Aicardi-Goutières syndrome: a model disease for systemic autoimmunity
- (2013) M. A. Lee-Kirsch et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Oxidative Damage of DNA Confers Resistance to Cytosolic Nuclease TREX1 Degradation and Potentiates STING-Dependent Immune Sensing
- (2013) Nadine Gehrke et al. IMMUNITY
- TDP-43 frontotemporal lobar degeneration and autoimmune disease
- (2013) Z. A. Miller et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING
- (2013) Xu Zhang et al. MOLECULAR CELL
- Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP
- (2013) Andrea Ablasser et al. NATURE
- Autoimmune disease preceding amyotrophic lateral sclerosis: An epidemiologic study
- (2013) M. R. Turner et al. NEUROLOGY
- STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease
- (2013) J. Petrasek et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pivotal Roles of cGAS-cGAMP Signaling in Antiviral Defense and Immune Adjuvant Effects
- (2013) X.-D. Li et al. SCIENCE
- Extracellular M. tuberculosis DNA Targets Bacteria for Autophagy by Activating the Host DNA-Sensing Pathway
- (2012) Robert O. Watson et al. CELL
- Mycobacterium Tuberculosis Activates the DNA-Dependent Cytosolic Surveillance Pathway within Macrophages
- (2012) Paolo S. Manzanillo et al. Cell Host & Microbe
- New insights into mechanisms of therapeutic effects of antimalarial agents in SLE
- (2012) Daniel J. Wallace et al. Nature Reviews Rheumatology
- Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
- (2012) L. Sun et al. SCIENCE
- Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort
- (2011) B Namjou et al. GENES AND IMMUNITY
- IFN- Production by Plasmacytoid Dendritic Cells Stimulated with RNA-Containing Immune Complexes Is Promoted by NK Cells via MIP-1 and LFA-1
- (2011) N. Hagberg et al. JOURNAL OF IMMUNOLOGY
- A diverse range of gene products are effectors of the type I interferon antiviral response
- (2011) John W. Schoggins et al. NATURE
- An autoimmune disease prevented by anti-retroviral drugs
- (2011) Gabriele B Beck-Engeser et al. Retrovirology
- Synoviocyte innate immune responses: TANK-binding kinase-1 as a potential therapeutic target in rheumatoid arthritis
- (2011) D. Hammaker et al. RHEUMATOLOGY
- Cytokines as therapeutic targets in SLE
- (2010) Lars Rönnblom et al. Nature Reviews Rheumatology
- STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
- (2009) Hiroki Ishikawa et al. NATURE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now