Overview of STING-Associated Vasculopathy with Onset in Infancy (SAVI) Among 21 Patients

Type 1 interferonopathy presenting as juvenile idiopathic arthritis with interstitial lung disease: report of a new phenotype

(2020) S. L. N. Clarke et al.   Pediatric Rheumatology

Interferon-Independent Activities of Mammalian STING Mediate Antiviral Response and Tumor Immune Evasion

(2020) Jianjun Wu et al.   IMMUNITY

A novel STING1 variant causes a recessive form of STING-associated vasculopathy with onset in infancy (SAVI)

(2020) Bin Lin et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A defect in COPI-mediated transport of STING causes immune dysregulation in COPA syndrome

(2020) Zimu Deng et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Type I Interferonopathies: from a Novel Concept to Targeted Therapeutics

(2020) Isabelle Melki et al.   Current Rheumatology Reports

Case Report: Acute Thrombotic Microangiopathy in a Patient with STING-Associated Vasculopathy with Onset in Infancy (SAVI)

(2020) Mia Ma et al.   JOURNAL OF CLINICAL IMMUNOLOGY

First Egyptian patient with STING-associated vasculopathy with onset in infancy

(2019) W Shoman et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

STING-mediated disruption of calcium homeostasis chronically activates ER stress and primes T cell death

(2019) Jianjun Wu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

STING-associated lung disease in mice relies on T cells but not type I interferon

(2019) Hella Luksch et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Efficacy and Adverse Events During Janus Kinase Inhibitor Treatment of SAVI Syndrome

(2019) Stefano Volpi et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Hierarchy of clinical manifestations in SAVI N153S and V154M mouse models

(2019) Mona Motwani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Baricitinib experience on STING-associated vasculopathy with onset in infancy: A representative case from Turkey

(2019) Sibel Balci et al.   CLINICAL IMMUNOLOGY

STING-Associated Vasculopathy with Onset in Infancy in Three Children with New Clinical Aspect and Unsatisfactory Therapeutic Responses to Tofacitinib

(2019) Xiaolei Tang et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Novel TMEM173 Mutation and the Role of Disease Modifying Alleles

(2019) Salla Keskitalo et al.   Frontiers in Immunology

Severe combined immunodeficiency in stimulator of interferon genes (STING) V154M/wild-type mice

(2018) Delphine Bouis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies

(2018) Gina A. Montealegre Sanchez et al.   JOURNAL OF CLINICAL INVESTIGATION

Pro-inflammation Associated with a Gain-of-Function Mutation (R284S) in the Innate Immune Sensor STING

(2018) Hiroyasu Konno et al.   Cell Reports

Brief Report: The Genetic Profile of Rheumatoid Factor-Positive Polyarticular Juvenile Idiopathic Arthritis Resembles That of Adult Rheumatoid Arthritis

(2018) Anne Hinks et al.   Arthritis & Rheumatology

A Mutation Outside the Dimerization Domain Causing Atypical STING-Associated Vasculopathy With Onset in Infancy

(2018) Rohit G. Saldanha et al.   Frontiers in Immunology

Targeting STING with covalent small-molecule inhibitors

(2018) Simone M. Haag et al.   NATURE

Disease-associated mutations identify a novel region in human STING necessary for the control of type I interferon signaling

(2017) Isabelle Melki et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes

(2017) Silvia Cerboni et al.   JOURNAL OF EXPERIMENTAL MEDICINE

STING-associated vasculopathy develops independently of IRF3 in mice

(2017) James D. Warner et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Detection of interferon alpha protein reveals differential levels and cellular sources in disease

(2017) Mathieu P. Rodero et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Type I interferonopathy in a young adult

(2017) Menelaos N. Manoussakis et al.   RHEUMATOLOGY

Type I interferon-mediated autoinflammation due to DNase II deficiency

(2017) Mathieu P. Rodero et al.   Nature Communications

Interstitial Lung Disease Caused by STING-associated Vasculopathy with Onset in Infancy

(2016) Sarah L. N. Clarke et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Familial chilblain lupus due to a gain-of-function mutation in STING

(2016) Nadja König et al.   ANNALS OF THE RHEUMATIC DISEASES

Severe Pulmonary Fibrosis as the First Manifestation of Interferonopathy (TMEM173 Mutation)

(2016) Cécile Picard et al.   CHEST

Efficacy of the Janus kinase 1/2 inhibitor ruxolitinib in the treatment of vasculopathy associated with TMEM173 -activating mutations in 3 children

(2016) Marie-Louise Frémond et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Type I interferon–mediated monogenic autoinflammation: The type I interferonopathies, a conceptual overview

(2016) Mathieu P. Rodero et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Failure to thrive, interstitial lung disease, and progressive digital necrosis with onset in infancy

(2016) Justin Chia et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Characterization of human disease phenotypes associated with mutations inTREX1,RNASEH2A,RNASEH2B,RNASEH2C,SAMHD1,ADAR, andIFIH1

(2015) Yanick J. Crow et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

An official European Respiratory Society/American Thoracic Society research statement: interstitial pneumonia with autoimmune features

(2015) Aryeh Fischer et al.   EUROPEAN RESPIRATORY JOURNAL

COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis

(2015) Levi B Watkin et al.   NATURE GENETICS

Neuroradiologic patterns and novel imaging findings in Aicardi-Goutières syndrome

(2015) Roberta La Piana et al.   NEUROLOGY

Severe Jaccoud’s arthropathy in systemic lupus erythematosus

(2015) Mittermayer B. Santiago et al.   RHEUMATOLOGY INTERNATIONAL

Stimulator of Interferon Genes–Associated Vasculopathy With Onset in Infancy

(2015) Justine Munoz et al.   JAMA Dermatology

Stimulator of Interferon Genes-Associated Vasculitis of Infancy

(2015) Ebun Omoyinmi et al.   Arthritis & Rheumatology

Inherited STING-activating mutation underlies a familial inflammatory syndrome with lupus-like manifestations

(2014) Nadia Jeremiah et al.   JOURNAL OF CLINICAL INVESTIGATION

Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation

(2014) Xianqin Zhang et al.   NATURE

Activated STING in a Vascular and Pulmonary Syndrome

(2014) Yin Liu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Assessment of interferon-related biomarkers in Aicardi-Goutières syndrome associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, and ADAR: a case-control study

(2013) Gillian I Rice et al.   LANCET NEUROLOGY

Association of Interferon- and Transforming Growth Factor β-Regulated Genes and Macrophage Activation With Systemic Sclerosis-Related Progressive Lung Fibrosis

(2013) Romy B. Christmann et al.   Arthritis & Rheumatology

Type I interferonopathies: a novel set of inborn errors of immunity

(2011) Yanick J. Crow   Annals of the New York Academy of Sciences

Type I interferon system activation and association with disease manifestations in systemic sclerosis

(2010) M.-L. Eloranta et al.   ANNALS OF THE RHEUMATIC DISEASES

Jaccoud’s arthropathy and psoriatic arthritis, a rare association

(2009) Yumei Wu et al.   RHEUMATOLOGY INTERNATIONAL

Fleischner Society: Glossary of Terms for Thoracic Imaging

(2008) David M. Hansell et al.   RADIOLOGY