The commensal skin microbiota triggers type I IFN–dependent innate repair responses in injured skin

Microbial guardians of skin health

(2019) Apollo Stacy et al.   SCIENCE

Dysbiosis of Skin Microbiota in Psoriatic Patients: Co-occurrence of Fungal and Bacterial Communities

(2019) Zuzana Stehlikova et al.   Frontiers in Microbiology

L1 drives IFN in senescent cells and promotes age-associated inflammation

(2019) Marco De Cecco et al.   NATURE

Microbiota-Driven Tonic Interferon Signals in Lung Stromal Cells Protect from Influenza Virus Infection

(2019) Konrad C. Bradley et al.   Cell Reports

Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair

(2018) Jonathan L. Linehan et al.   CELL

Nrf2-Mediated Fibroblast Reprogramming Drives Cellular Senescence by Targeting the Matrisome

(2018) Paul Hiebert et al.   DEVELOPMENTAL CELL

Autophagy proteins suppress protective type I interferon signalling in response to the murine gut microbiota

(2018) Patricia K. Martin et al.   Nature Microbiology

Commensal-specific T cell plasticity promotes rapid tissue adaptation to injury

(2018) Oliver J. Harrison et al.   SCIENCE

Temporal Stability in Chronic Wound Microbiota Is Associated With Poor Healing

(2017) Michael Loesche et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

RIG-I/MAVS and STING signaling promote gut integrity during irradiation- and immune-mediated tissue injury

(2017) Julius C. Fischer et al.   Science Translational Medicine

CXCL10 Acts as a Bifunctional Antimicrobial Molecule against Bacillus anthracis

(2016) Katie R. Margulieux et al.   mBio

Type I Interferons Link Viral Infection to Enhanced Epithelial Turnover and Repair

(2015) Lulu Sun et al.   Cell Host & Microbe

Commensal–dendritic-cell interaction specifies a unique protective skin immune signature

(2015) Shruti Naik et al.   NATURE

Liquid-crystalline ordering of antimicrobial peptide–DNA complexes controls TLR9 activation

(2015) Nathan W. Schmidt et al.   NATURE MATERIALS

An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA

(2014) Marco Demaria et al.   DEVELOPMENTAL CELL

Cationic antimicrobial peptides in psoriatic skin cooperate to break innate tolerance to self-DNA

(2014) Roberto Lande et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Wound repair and regeneration: Mechanisms, signaling, and translation

(2014) S. A. Eming et al.   Science Translational Medicine

Investigation of the cutaneous response to recall antigen in humansin vivo

(2013) A. N. Akbar et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

A hypomorphic mutation in the Gfi1 transcriptional repressor results in a novel form of neutropenia

(2012) Diana Ordoñez-Rueda et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IFN-α Enhances IL-22 Receptor Expression in Keratinocytes: A Possible Role in the Development of Psoriasis

(2012) Mikiko Tohyama et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Antimicrobial Activities of Chemokines: Not Just a Side-Effect?

(2012) Marlene Wolf et al.   Frontiers in Immunology

Plasmacytoid dendritic cells sense skin injury and promote wound healing through type I interferons

(2010) Josh Gregorio et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human skin wounds: A major and snowballing threat to public health and the economy

(2009) Chandan K. Sen et al.   WOUND REPAIR AND REGENERATION

Wound repair and regeneration

(2008) Geoffrey C. Gurtner et al.   NATURE