The cGAS–STING pathway drives type I IFN immunopathology in COVID-19
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Title
The cGAS–STING pathway drives type I IFN immunopathology in COVID-19
Authors
Keywords
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Journal
NATURE
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-01-20
DOI
10.1038/s41586-022-04421-w
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Note: Only part of the references are listed.- SARS-CoV-2 infection induces a pro-inflammatory cytokine response through cGAS-STING and NF-κB
- (2022) Christopher J. Neufeldt et al. Communications Biology
- Rapid endotheliitis and vascular damage characterize SARS‐CoV‐2 infection in a human lung‐chip model
- (2021) Vivek V Thacker et al. EMBO REPORTS
- Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV
- (2021) Alexey Stukalov et al. NATURE
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- (2021) Donna L. Farber NATURE
- Postmortem Cardiopulmonary Pathology in Patients with COVID-19 Infection: Single-Center Report of 12 Autopsies from Lausanne, Switzerland
- (2021) Sabina Berezowska et al. Diagnostics
- Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
- (2020) Chaolin Huang et al. LANCET
- VDAC oligomers form mitochondrial pores to release mtDNA fragments and promote lupus-like disease
- (2020) Jeonghan Kim et al. SCIENCE
- Heightened Innate Immune Responses in the Respiratory Tract of COVID-19 Patients
- (2020) Zhuo Zhou et al. Cell Host & Microbe
- Type I and Type III Interferons – Induction, Signaling, Evasion, and Application to Combat COVID-19
- (2020) Annsea Park et al. Cell Host & Microbe
- Endothelial cell infection and endotheliitis in COVID-19
- (2020) Zsuzsanna Varga et al. LANCET
- Virological assessment of hospitalized patients with COVID-2019
- (2020) Roman Wölfel et al. NATURE
- The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice
- (2020) Linlin Bao et al. NATURE
- Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19
- (2020) Mingfeng Liao et al. NATURE MEDICINE
- Severe COVID-19 is marked by a dysregulated myeloid cell compartment
- (2020) Jonas Schulte-Schrepping et al. CELL
- Retrospective Multicenter Cohort Study Shows Early Interferon Therapy Is Associated with Favorable Clinical Responses in COVID-19 Patients
- (2020) Nan Wang et al. Cell Host & Microbe
- Presence of Genetic Variants Among Young Men With Severe COVID-19
- (2020) Caspar I. van der Made et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling
- (2020) Benjamin Israelow et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The spectrum of COVID-19-associated dermatologic manifestations: an international registry of 716 patients from 31 countries
- (2020) Esther E. Freeman et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- Longitudinal analyses reveal immunological misfiring in severe COVID-19
- (2020) Carolina Lucas et al. NATURE
- COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis
- (2020) Robert Lorenz Chua et al. NATURE BIOTECHNOLOGY
- A single-cell atlas of the peripheral immune response in patients with severe COVID-19
- (2020) Aaron J. Wilk et al. NATURE MEDICINE
- Extrapulmonary manifestations of COVID-19
- (2020) Aakriti Gupta et al. NATURE MEDICINE
- Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients
- (2020) Jérôme Hadjadj et al. SCIENCE
- Endotheliopathy in COVID-19-associated coagulopathy: evidence from a single-centre, cross-sectional study
- (2020) George Goshua et al. Lancet Haematology
- Immunophenotyping of COVID-19 and influenza highlights the role of type I interferons in development of severe COVID-19
- (2020) Jeong Seok Lee et al. Science Immunology
- Altered bioenergetics and mitochondrial dysfunction of monocytes in patients with COVID‐19 pneumonia
- (2020) Lara Gibellini et al. EMBO Molecular Medicine
- Animal models for COVID-19
- (2020) César Muñoz-Fontela et al. NATURE
- SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function
- (2020) Emma S. Winkler et al. NATURE IMMUNOLOGY
- Inborn errors of type I IFN immunity in patients with life-threatening COVID-19
- (2020) Qian Zhang et al. SCIENCE
- Two distinct immunopathological profiles in autopsy lungs of COVID-19
- (2020) Ronny Nienhold et al. Nature Communications
- Human angiotensin-converting enzyme 2 transgenic mice infected with SARS-CoV-2 develop severe and fatal respiratory disease
- (2020) Joseph W. Golden et al. JCI Insight
- Untuned antiviral immunity in COVID-19 revealed by temporal type I/III interferon patterns and flu comparison
- (2020) Ioanna-Evdokia Galani et al. NATURE IMMUNOLOGY
- Recombinant ACE2 Expression Is Required for SARS-CoV-2 To Infect Primary Human Endothelial Cells and Induce Inflammatory and Procoagulative Responses
- (2020) Jonas Nascimento Conde et al. mBio
- cGAS in action: Expanding roles in immunity and inflammation
- (2019) Andrea Ablasser et al. SCIENCE
- Dampened STING-Dependent Interferon Activation in Bats
- (2018) Jiazheng Xie et al. Cell Host & Microbe
- Targeting STING with covalent small-molecule inhibitors
- (2018) Simone M. Haag et al. NATURE
- Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue
- (2017) Deanna L. Plubell et al. MOLECULAR & CELLULAR PROTEOMICS
- MSFragger: ultrafast and comprehensive peptide identification in mass spectrometry–based proteomics
- (2017) Andy T Kong et al. NATURE METHODS
- Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice
- (2016) Rudragouda Channappanavar et al. Cell Host & Microbe
- limma powers differential expression analyses for RNA-sequencing and microarray studies
- (2015) Matthew E. Ritchie et al. NUCLEIC ACIDS RESEARCH
- Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation
- (2015) S. Liu et al. SCIENCE
- MS Amanda, a Universal Identification Algorithm Optimized for High Accuracy Tandem Mass Spectra
- (2014) Viktoria Dorfer et al. JOURNAL OF PROTEOME RESEARCH
- Activated STING in a Vascular and Pulmonary Syndrome
- (2014) Yin Liu et al. NEW ENGLAND JOURNAL OF MEDICINE
- ReadqPCR and NormqPCR: R packages for the reading, quality checking and normalisation of RT-qPCR quantification cycle (Cq) data
- (2012) James R Perkins et al. BMC GENOMICS
- 5,6-Dimethylxanthenone-4-acetic Acid (DMXAA) Activates Stimulator of Interferon Gene (STING)-dependent Innate Immune Pathways and Is Regulated by Mitochondrial Membrane Potential
- (2012) Daniel Prantner et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Protective Role of Toll-like Receptor 3-Induced Type I Interferon in Murine Coronavirus Infection of Macrophages
- (2012) Liudmila Mazaleuskaya et al. Viruses-Basel
- edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
- (2009) M. D. Robinson et al. BIOINFORMATICS
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