Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
Authors
Keywords
-
Journal
NATURE
Volume 530, Issue 7589, Pages 184-189
Publisher
Springer Nature
Online
2016-02-04
DOI
10.1038/nature16932
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Rapamycin-mediated mTORC2 inhibition is determined by the relative expression of FK506-binding proteins
- (2015) Katherine H. Schreiber et al. AGING CELL
- Cellular senescence in aging and age-related disease: from mechanisms to therapy
- (2015) Bennett G Childs et al. NATURE MEDICINE
- An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA
- (2014) Marco Demaria et al. DEVELOPMENTAL CELL
- The role of senescent cells in ageing
- (2014) Jan M. van Deursen NATURE
- Spartan deficiency causes genomic instability and progeroid phenotypes
- (2014) Reeja S. Maskey et al. Nature Communications
- Monitoring Tumorigenesis and Senescence In Vivo with a p16INK4a-Luciferase Model
- (2013) Christin E. Burd et al. CELL
- Programmed Cell Senescence during Mammalian Embryonic Development
- (2013) Daniel Muñoz-Espín et al. CELL
- Senescence Is a Developmental Mechanism that Contributes to Embryonic Growth and Patterning
- (2013) Mekayla Storer et al. CELL
- Chronic rapamycin treatment or lack ofS6K1does not reduce ribosome activity in vivo
- (2013) Michael G Garelick et al. CELL CYCLE
- p21 Both Attenuates and Drives Senescence and Aging in BubR1 Progeroid Mice
- (2013) Darren J. Baker et al. Cell Reports
- Aging, Cellular Senescence, and Cancer
- (2012) Judith Campisi Annual Review of Physiology
- Bub1 kinase activity drives error correction and mitotic checkpoint control but not tumor suppression
- (2012) Robin M. Ricke et al. JOURNAL OF CELL BIOLOGY
- Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan
- (2012) Darren J. Baker et al. NATURE CELL BIOLOGY
- Genetic coregulation of age of female sexual maturation and lifespan through circulating IGF1 among inbred mouse strains
- (2012) R. Yuan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Expression of ROR t Marks a Pathogenic Regulatory T Cell Subset in Human Colon Cancer
- (2012) N. R. Blatner et al. Science Translational Medicine
- Reduced Life- and Healthspan in Mice Carrying a Mono-Allelic BubR1 MVA Mutation
- (2012) Tobias Wijshake et al. PLoS Genetics
- The starvation hormone, fibroblast growth factor-21, extends lifespan in mice
- (2012) Yuan Zhang et al. eLife
- Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
- (2011) Darren J. Baker et al. NATURE
- Fat tissue, aging, and cellular senescence
- (2010) Tamara Tchkonia et al. AGING CELL
- Ageing-induced decline in physical endurance in mice is associated with decrease in cardiac SUR2A and increase in cardiac susceptibility to metabolic stress: therapeutic prospects for up-regulation of SUR2A
- (2010) Rajni Sudhir et al. BIOGERONTOLOGY
- The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing
- (2010) Joon-Il Jun et al. NATURE CELL BIOLOGY
- Expression ofp16INK4ain peripheral blood T-cells is a biomarker of human aging
- (2009) Yan Liu et al. AGING CELL
- Apoptosis of Hippocampal Pyramidal Neurons Is Virus Independent in a Mouse Model of Acute Neurovirulent Picornavirus Infection
- (2009) Eric J. Buenz et al. AMERICAN JOURNAL OF PATHOLOGY
- Senescence of Activated Stellate Cells Limits Liver Fibrosis
- (2008) Valery Krizhanovsky et al. CELL
- The Aging Cardiomyocyte: A Mini-Review
- (2008) D. Bernhard et al. GERONTOLOGY
- Opposing roles for p16Ink4a and p19Arf in senescence and ageing caused by BubR1 insufficiency
- (2008) Darren J. Baker et al. NATURE CELL BIOLOGY
- Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice
- (2007) Colin Selman et al. FASEB JOURNAL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started