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Title
Engineering the next generation of cell-based therapeutics
Authors
Keywords
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Journal
NATURE REVIEWS DRUG DISCOVERY
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-05-30
DOI
10.1038/s41573-022-00476-6
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- (2022) Elie Dolgin NATURE BIOTECHNOLOGY
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- (2021) Tian Zhou et al. Journal of Hematology & Oncology
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- (2021) Rogelio A. Hernandez-Lopez et al. SCIENCE
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- (2021) Jing Li et al. Nature Communications
- Current status and perspective of CAR-T and CAR-NK cell therapy trials in Germany
- (2021) Nawid Albinger et al. GENE THERAPY
- CRISPR/Cas-Based Epigenome Editing: Advances, Applications, and Clinical Utility
- (2021) Jacob H. Goell et al. TRENDS IN BIOTECHNOLOGY
- An inverse-breathing encapsulation system for cell delivery
- (2021) Long-Hai Wang et al. Science Advances
- Cryomicroneedles for transdermal cell delivery
- (2021) Hao Chang et al. Nature Biomedical Engineering
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- (2021) Morgane Boulch et al. Science Immunology
- Adipose-Derived Stem Cells in the Treatment of Perianal Fistulas in Crohn’s Disease: Rationale, Clinical Results and Perspectives
- (2021) Etienne Buscail et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- How stem cells could fix type 1 diabetes
- (2021) Liam Drew NATURE
- Transgenic mice for in vivo epigenome editing with CRISPR-based systems
- (2021) Matthew P. Gemberling et al. NATURE METHODS
- Generation of insulin-producing pancreatic β cells from multiple human stem cell lines
- (2021) Nathaniel J. Hogrebe et al. Nature Protocols
- Hypoimmune induced pluripotent stem cell–derived cell therapeutics treat cardiovascular and pulmonary diseases in immunocompetent allogeneic mice
- (2021) Tobias Deuse et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A therapeutic convection–enhanced macroencapsulation device for enhancing β cell viability and insulin secretion
- (2021) Kisuk Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Strategies for durable β cell replacement in type 1 diabetes
- (2021) Todd M. Brusko et al. SCIENCE
- Design Considerations for Macroencapsulation Devices for Stem Cell Derived Islets for the Treatment of Type 1 Diabetes
- (2021) Debkalpa Goswami et al. Advanced Science
- The surface topography of silicone breast implants mediates the foreign body response in mice, rabbits and humans
- (2021) Joshua C. Doloff et al. Nature Biomedical Engineering
- Implanted pluripotent stem-cell-derived pancreatic endoderm cells secrete glucose-responsive C-peptide in patients with type 1 diabetes
- (2021) Adam Ramzy et al. Cell Stem Cell
- Cellular Therapy Updates in B-Cell Lymphoma: The State of the CAR-T
- (2021) Zachary D. Crees et al. Cancers
- The promise and challenge of therapeutic genome editing
- (2020) Jennifer A. Doudna NATURE
- Use of CAR-Transduced Natural Killer Cells in CD19-Positive Lymphoid Tumors
- (2020) Enli Liu et al. NEW ENGLAND JOURNAL OF MEDICINE
- CRISPR-engineered T cells in patients with refractory cancer
- (2020) Edward A. Stadtmauer et al. SCIENCE
- The COMET toolkit for composing customizable genetic programs in mammalian cells
- (2020) Patrick S. Donahue et al. Nature Communications
- Therapeutic potential of stem cells for treatment of neurodegenerative diseases
- (2020) Hamid Ahmadian-Moghadam et al. BIOTECHNOLOGY LETTERS
- Pooled Knockin Targeting for Genome Engineering of Cellular Immunotherapies
- (2020) Theodore L. Roth et al. CELL
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- (2020) Michael Klichinsky et al. NATURE BIOTECHNOLOGY
- Cas9 activates the p53 pathway and selects for p53-inactivating mutations
- (2020) Oana M. Enache et al. NATURE GENETICS
- Next-generation stem cells — ushering in a new era of cell-based therapies
- (2020) Erin A. Kimbrel et al. NATURE REVIEWS DRUG DISCOVERY
- Unconstrained genome targeting with near-PAMless engineered CRISPR-Cas9 variants
- (2020) Russell T. Walton et al. SCIENCE
- Electrogenetic cellular insulin release for real-time glycemic control in type 1 diabetic mice
- (2020) Krzysztof Krawczyk et al. SCIENCE
- Advantages and Recent Developments of Autologous Cell Therapy for Parkinson’s Disease Patients
- (2020) Teresia M. Osborn et al. Frontiers in Cellular Neuroscience
- In Vivo Targeting of Clostridioides difficile Using Phage-Delivered CRISPR-Cas3 Antimicrobials
- (2020) Kurt Selle et al. mBio
- Immune Modulation by Design: Using Topography to Control Human Monocyte Attachment and Macrophage Differentiation
- (2020) Matthew J. Vassey et al. Advanced Science
- A retrievable implant for the long-term encapsulation and survival of therapeutic xenogeneic cells
- (2020) Suman Bose et al. Nature Biomedical Engineering
- Angiogenesis in Tissue Engineering: As Nature Intended?
- (2020) Valeria Mastrullo et al. Frontiers in Bioengineering and Biotechnology
- Engineering the drug carrier biointerface to overcome biological barriers to drug delivery
- (2020) Joel A. Finbloom et al. ADVANCED DRUG DELIVERY REVIEWS
- Genome editing of mutant KRAS through supramolecular polymer-mediated delivery of Cas9 ribonucleoprotein for colorectal cancer therapy
- (2020) Tao Wan et al. JOURNAL OF CONTROLLED RELEASE
- Engineered off-the-shelf therapeutic T cells resist host immune rejection
- (2020) Feiyan Mo et al. NATURE BIOTECHNOLOGY
- The delivery challenge: fulfilling the promise of therapeutic genome editing
- (2020) Joost van Haasteren et al. NATURE BIOTECHNOLOGY
- Thermal Control of Engineered T-cells
- (2020) Mohamad H. Abedi et al. ACS Synthetic Biology
- Perspectives on Synthetic Materials to Guide Tissue Regeneration for Osteochondral Defect Repair
- (2020) Michael T. Frassica et al. ACS Biomaterials-Science & Engineering
- Materials design for bone-tissue engineering
- (2020) Gerry L. Koons et al. Nature Reviews Materials
- Single C-to-T substitution using engineered APOBEC3G-nCas9 base editors with minimum genome- and transcriptome-wide off-target effects
- (2020) Sangsin Lee et al. Science Advances
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- (2020) Ian S. Kinstlinger et al. Nature Biomedical Engineering
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- (2020) Shebli Atrash et al. Clinical Lymphoma Myeloma & Leukemia
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- (2020) Yulia Panina et al. EXPERIMENTAL AND MOLECULAR MEDICINE
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- (2020) Marc J. Lajoie et al. SCIENCE
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- (2019) Tobias Deuse et al. NATURE BIOTECHNOLOGY
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- (2019) Erminia Mariani et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2019) Huaigeng Xu et al. Cell Stem Cell
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- (2019) Hector Mayani et al. BONE MARROW TRANSPLANTATION
- Delivering cellular and gene therapies to patients: solutions for realizing the potential of the next generation of medicine
- (2019) Kris Elverum et al. GENE THERAPY
- Targeting a Pre-existing Anti-transgene T Cell Response for Effective Gene Therapy of MPS-I in the Mouse Model of the Disease
- (2019) Giorgia Squeri et al. MOLECULAR THERAPY
- The next generation of CRISPR–Cas technologies and applications
- (2019) Adrian Pickar-Oliver et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Generation of hypoimmunogenic human pluripotent stem cells
- (2019) Xiao Han et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Complex signal processing in synthetic gene circuits using cooperative regulatory assemblies
- (2019) Caleb J. Bashor et al. SCIENCE
- Multivascular networks and functional intravascular topologies within biocompatible hydrogels
- (2019) Bagrat Grigoryan et al. SCIENCE
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- (2019) Anna Domaszewska-Szostek et al. ANNALS OF PLASTIC SURGERY
- Transposon-encoded CRISPR–Cas systems direct RNA-guided DNA integration
- (2019) Sanne E. Klompe et al. NATURE
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- (2019) Shady Farah et al. NATURE MATERIALS
- RNA-guided DNA insertion with CRISPR-associated transposases
- (2019) Jonathan Strecker et al. SCIENCE
- 3D bioprinting of collagen to rebuild components of the human heart
- (2019) A. Lee et al. SCIENCE
- Targeted transcriptional modulation with type I CRISPR–Cas systems in human cells
- (2019) Adrian Pickar-Oliver et al. NATURE BIOTECHNOLOGY
- Epicardial cells derived from human embryonic stem cells augment cardiomyocyte-driven heart regeneration
- (2019) Johannes Bargehr et al. NATURE BIOTECHNOLOGY
- Next-generation regulatory T cell therapy
- (2019) Leonardo M. R. Ferreira et al. NATURE REVIEWS DRUG DISCOVERY
- Transplantation of gene-modified haematopoietic stem cells: Application and clinical considerations
- (2019) M Alessandrini et al. SAMJ SOUTH AFRICAN MEDICAL JOURNAL
- Biomanufacturing of organ-specific tissues with high cellular density and embedded vascular channels
- (2019) Mark A. Skylar-Scott et al. Science Advances
- Voxelated soft matter via multimaterial multinozzle 3D printing
- (2019) Mark A. Skylar-Scott et al. NATURE
- Search-and-replace genome editing without double-strand breaks or donor DNA
- (2019) Andrew V. Anzalone et al. NATURE
- Harnessing type I CRISPR–Cas systems for genome engineering in human cells
- (2019) Peter Cameron et al. NATURE BIOTECHNOLOGY
- Zwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation
- (2019) Qingsheng Liu et al. Nature Communications
- Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors
- (2019) Beau R. Webber et al. Nature Communications
- Adaptive features of innate immune cells and their relevance to graft rejection
- (2019) Guangchuan Wang et al. Current Opinion in Organ Transplantation
- Alginate microencapsulated human hepatocytes for the treatment of acute liver failure in children
- (2019) Anil Dhawan et al. JOURNAL OF HEPATOLOGY
- Artificial signaling in mammalian cells enabled by prokaryotic two-component system
- (2019) Alain Mazé et al. Nature Chemical Biology
- Neurons differentiate magnitude and location of mechanical stimuli
- (2019) Benjamin M. Gaub et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nitinol thin films functionalized with CAR-T cells for the treatment of solid tumours
- (2019) Michael E. Coon et al. Nature Biomedical Engineering
- Cell Encapsulation Within Alginate Microcapsules: Immunological Challenges and Outlook
- (2019) Assem Ashimova et al. Frontiers in Bioengineering and Biotechnology
- Cell encapsulation: Overcoming barriers in cell transplantation in diabetes and beyond
- (2018) Marco Farina et al. ADVANCED DRUG DELIVERY REVIEWS
- Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors
- (2018) Silvana Konermann et al. CELL
- Universal Chimeric Antigen Receptors for Multiplexed and Logical Control of T Cell Responses
- (2018) Jang Hwan Cho et al. CELL
- CRISPR-Based Chromatin Remodeling of the Endogenous Oct4 or Sox2 Locus Enables Reprogramming to Pluripotency
- (2018) Peng Liu et al. Cell Stem Cell
- Clinical Studies of Cell Therapy in Cardiovascular Medicine
- (2018) Monisha N. Banerjee et al. CIRCULATION RESEARCH
- Initial Clinical Evaluation of VC-01TM Combination Product—A Stem Cell–Derived Islet Replacement for Type 1 Diabetes (T1D)
- (2018) ROBERT R. HENRY et al. DIABETES
- Stem Cell Therapies in Cardiovascular Disease
- (2018) Maia Terashvili et al. JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA
- An “off-the-shelf” fratricide-resistant CAR-T for the treatment of T cell hematologic malignancies
- (2018) Matthew L Cooper et al. LEUKEMIA
- Dose-Dependent Prevention of Metabolic and Neurologic Disease in Murine MPS II by ZFN-Mediated In Vivo Genome Editing
- (2018) Kanut Laoharawee et al. MOLECULAR THERAPY
- CAR-T Cells: A Systematic Review and Mixed Methods Analysis of the Clinical Trial Landscape
- (2018) David Pettitt et al. MOLECULAR THERAPY
- Phase 1 clinical study of an embryonic stem cell–derived retinal pigment epithelium patch in age-related macular degeneration
- (2018) Lyndon da Cruz et al. NATURE BIOTECHNOLOGY
- Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements
- (2018) Michael Kosicki et al. NATURE BIOTECHNOLOGY
- Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction
- (2018) Luke W Koblan et al. NATURE BIOTECHNOLOGY
- Rewiring T-cell responses to soluble factors with chimeric antigen receptors
- (2018) ZeNan L Chang et al. Nature Chemical Biology
- Generalized extracellular molecule sensor platform for programming cellular behavior
- (2018) Leo Scheller et al. Nature Chemical Biology
- CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response
- (2018) Emma Haapaniemi et al. NATURE MEDICINE
- An enhanced CRISPR repressor for targeted mammalian gene regulation
- (2018) Nan Cher Yeo et al. NATURE METHODS
- In vivo simultaneous transcriptional activation of multiple genes in the brain using CRISPR–dCas9-activator transgenic mice
- (2018) Haibo Zhou et al. NATURE NEUROSCIENCE
- Gene Therapy in Patients with Transfusion-Dependent β-Thalassemia
- (2018) Alexis A. Thompson et al. NEW ENGLAND JOURNAL OF MEDICINE
- Programming gene and engineered-cell therapies with synthetic biology
- (2018) Tasuku Kitada et al. SCIENCE
- CAR T cell immunotherapy for human cancer
- (2018) Carl H. June et al. SCIENCE
- Human pluripotent reprogramming with CRISPR activators
- (2018) Jere Weltner et al. Nature Communications
- RNA-guided transcriptional silencing in vivo with S. aureus CRISPR-Cas9 repressors
- (2018) Pratiksha I. Thakore et al. Nature Communications
- The Foreign Body Response Demystified
- (2018) Yashoda Chandorkar et al. ACS Biomaterials-Science & Engineering
- The Foreign Body Response Demystified
- (2018) Yashoda Chandorkar et al. ACS Biomaterials Science & Engineering
- Reprogramming human T cell function and specificity with non-viral genome targeting
- (2018) Theodore L. Roth et al. NATURE
- Evolved Cas9 variants with broad PAM compatibility and high DNA specificity
- (2018) Johnny H. Hu et al. NATURE
- Adoptive Cell Therapy in Treating Pediatric Solid Tumors
- (2018) Mekdem Tesfaye et al. Current Oncology Reports
- Alginate encapsulation as long-term immune protection of allogeneic pancreatic islet cells transplanted into the omental bursa of macaques
- (2018) Matthew A. Bochenek et al. Nature Biomedical Engineering
- Reduction of measurement noise in a continuous glucose monitor by coating the sensor with a zwitterionic polymer
- (2018) Xi Xie et al. Nature Biomedical Engineering
- Programmable design of orthogonal protein heterodimers
- (2018) Zibo Chen et al. NATURE
- High prevalence of Streptococcus pyogenes Cas9-reactive T cells within the adult human population
- (2018) Dimitrios L. Wagner et al. NATURE MEDICINE
- Calibration of CAR activation potential directs alternative T cell fates and therapeutic potency
- (2018) Judith Feucht et al. NATURE MEDICINE
- Base editing: precision chemistry on the genome and transcriptome of living cells
- (2018) Holly A. Rees et al. NATURE REVIEWS GENETICS
- Effect of Ciliary Neurotrophic Factor on Retinal Neurodegeneration in Patients with Macular Telangiectasia Type 2
- (2018) Emily Y. Chew et al. OPHTHALMOLOGY
- A phase IIb, randomised, double-blind, placebo-controlled, dose-ranging investigation of the safety and efficacy of NTCELL® [immunoprotected (alginate-encapsulated) porcine choroid plexus cells for xenotransplantation] in patients with Parkinson's disease
- (2018) Barry Snow et al. PARKINSONISM & RELATED DISORDERS
- Biomaterials for cell transplantation
- (2018) Nikolaos Mitrousis et al. Nature Reviews Materials
- Developing gene and cell therapies for rare diseases: an opportunity for synergy between academia and industry
- (2017) F Mavilio GENE THERAPY
- Generation of glucose-sensitive insulin-secreting beta-like cells from human embryonic stem cells by incorporating a synthetic lineage-control network
- (2017) Pratik Saxena et al. JOURNAL OF BIOTECHNOLOGY
- Rational Design of Evolutionarily Stable Microbial Kill Switches
- (2017) Finn Stirling et al. MOLECULAR CELL
- Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection
- (2017) Justin Eyquem et al. NATURE
- Enhanced proofreading governs CRISPR–Cas9 targeting accuracy
- (2017) Janice S. Chen et al. NATURE
- RNA targeting with CRISPR–Cas13
- (2017) Omar O. Abudayyeh et al. NATURE
- Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
- (2017) Nicole M. Gaudelli et al. NATURE
- Colony stimulating factor-1 receptor is a central component of the foreign body response to biomaterial implants in rodents and non-human primates
- (2017) Joshua C. Doloff et al. NATURE MATERIALS
- Advances in islet encapsulation technologies
- (2017) Tejal Desai et al. NATURE REVIEWS DRUG DISCOVERY
- Genome engineering: a new approach to gene therapy for neuromuscular disorders
- (2017) Christopher E. Nelson et al. Nature Reviews Neurology
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- (2017) Eric Tran et al. NEW ENGLAND JOURNAL OF MEDICINE
- dCas9-based epigenome editing suggests acquisition of histone methylation is not sufficient for target gene repression
- (2017) Henriette O’Geen et al. NUCLEIC ACIDS RESEARCH
- Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation
- (2017) Antonio Galleu et al. Science Translational Medicine
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- (2017) Vincent Ronfard et al. TISSUE ENGINEERING PART B-REVIEWS
- In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni
- (2017) Eunji Kim et al. Nature Communications
- Navigating Market Authorization: The Path Holoclar Took to Become the First Stem Cell Product Approved in the European Union
- (2017) Graziella Pellegrini et al. Stem Cells Translational Medicine
- Current and Future Perspectives on Alginate Encapsulated Pancreatic Islet
- (2017) Berit L. Strand et al. Stem Cells Translational Medicine
- Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6
- (2017) Rasmus O Bak et al. eLife
- 3D-printed vascular networks direct therapeutic angiogenesis in ischaemia
- (2017) T. Mirabella et al. Nature Biomedical Engineering
- Precision Tumor Recognition by T Cells With Combinatorial Antigen-Sensing Circuits
- (2016) Kole T. Roybal et al. CELL
- Editing DNA Methylation in the Mammalian Genome
- (2016) X. Shawn Liu et al. CELL
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- (2016) Joshua B. Black et al. Cell Stem Cell
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- (2016) Jiangtao Ren et al. CLINICAL CANCER RESEARCH
- Direct and indirect allograft recognition
- (2016) Christine M. Lin et al. Current Opinion in Organ Transplantation
- Heartbreak hotel: a convergence in cardiac regeneration
- (2016) Michael D. Schneider DEVELOPMENT
- The effect of chemically modified alginates on macrophage phenotype and biomolecule transport
- (2016) Hannah C. Bygd et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- 3D-printed fluidic networks as vasculature for engineered tissue
- (2016) Ian S. Kinstlinger et al. LAB ON A CHIP
- The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA
- (2016) Ines Fonfara et al. NATURE
- Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
- (2016) Alexis C. Komor et al. NATURE
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- (2016) Kelly A Schwarz et al. Nature Chemical Biology
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- (2016) Arturo J Vegas et al. NATURE MEDICINE
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- Efficient targeted DNA methylation with chimeric dCas9–Dnmt3a–Dnmt3L methyltransferase
- (2016) Peter Stepper et al. NUCLEIC ACIDS RESEARCH
- Engineering dynamical control of cell fate switching using synthetic phospho-regulons
- (2016) Russell M. Gordley et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- -cell-mimetic designer cells provide closed-loop glycemic control
- (2016) M. Xie et al. SCIENCE
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- (2016) Simon Ausländer et al. Cold Spring Harbor Perspectives in Biology
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- (2016) Patrick Guye et al. Nature Communications
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- (2016) Volkan Yesilyurt et al. Advanced Healthcare Materials
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- (2016) Panayiota Petrou et al. JAMA Neurology
- Clinical Benefit of Islet Xenotransplantation for the Treatment of Type 1 Diabetes
- (2016) Shinichi Matsumoto et al. EBioMedicine
- A CRISPR-based approach for targeted DNA demethylation
- (2016) Xingxing Xu et al. Cell Discovery
- Examination of the foreign body response to biomaterials by nonlinear intravital microscopy
- (2016) Eleonora Dondossola et al. Nature Biomedical Engineering
- Sipuleucel-T (Provenge®)—Autopsy of an Innovative Paradigm Change in Cancer Treatment: Why a Single-Product Biotech Company Failed to Capitalize on its Breakthrough Invention
- (2015) Szymon Jarosławski et al. BIODRUGS
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- (2015) Isaac B. Hilton et al. GENOME RESEARCH
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- (2015) Benjamin P. Kleinstiver et al. NATURE
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- (2015) Matthew C. Canver et al. NATURE
- Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
- (2015) Silvana Konermann et al. NATURE
- In vivo genome editing using Staphylococcus aureus Cas9
- (2015) F. Ann Ran et al. NATURE
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- (2015) Isaac B Hilton et al. NATURE BIOTECHNOLOGY
- Size- and shape-dependent foreign body immune response to materials implanted in rodents and non-human primates
- (2015) Omid Veiseh et al. NATURE MATERIALS
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- (2015) Alejandro Chavez et al. NATURE METHODS
- Remote control of therapeutic T cells through a small molecule-gated chimeric receptor
- (2015) C.-Y. Wu et al. SCIENCE
- Rationally engineered Cas9 nucleases with improved specificity
- (2015) I. M. Slaymaker et al. SCIENCE
- Wireless magnetothermal deep brain stimulation
- (2015) R. Chen et al. SCIENCE
- Implantable synthetic cytokine converter cells with AND-gate logic treat experimental psoriasis
- (2015) Lina Schukur et al. Science Translational Medicine
- Adoptive Cell Therapy—Tumor-Infiltrating Lymphocytes, T-Cell Receptors, and Chimeric Antigen Receptors
- (2015) Steven A. Feldman et al. SEMINARS IN ONCOLOGY
- Macrophages, Foreign Body Giant Cells and Their Response to Implantable Biomaterials
- (2015) Zeeshan Sheikh et al. Materials
- Switchable Release of Entrapped Nanoparticles from Alginate Hydrogels
- (2015) Cathal J. Kearney et al. Advanced Healthcare Materials
- Cell responses to metallic nanostructure arrays with complex geometries
- (2014) Zeinab Jahed et al. BIOMATERIALS
- A Protein-Tagging System for Signal Amplification in Gene Expression and Fluorescence Imaging
- (2014) Marvin E. Tanenbaum et al. CELL
- Biopolymer implants enhance the efficacy of adoptive T-cell therapy
- (2014) Sirkka B Stephan et al. NATURE BIOTECHNOLOGY
- Mesenchymal stem cells: immune evasive, not immune privileged
- (2014) James A Ankrum et al. NATURE BIOTECHNOLOGY
- A brief history of synthetic biology
- (2014) D. Ewen Cameron et al. NATURE REVIEWS MICROBIOLOGY
- Synthetic biology in mammalian cells: next generation research tools and therapeutics
- (2014) Florian Lienert et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia
- (2014) Shannon L. Maude et al. NEW ENGLAND JOURNAL OF MEDICINE
- Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector
- (2014) Ami M. Kabadi et al. NUCLEIC ACIDS RESEARCH
- RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection
- (2014) W. Hu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Programmable Removal of Bacterial Strains by Use of Genome-Targeting CRISPR-Cas Systems
- (2014) A. A. Gomaa et al. mBio
- A CRISPR/Cas9-Based System for Reprogramming Cell Lineage Specification
- (2014) Syandan Chakraborty et al. Stem Cell Reports
- Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
- (2013) Lei S. Qi et al. CELL
- CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
- (2013) Luke A. Gilbert et al. CELL
- Transplantation of human islets without immunosuppression
- (2013) B. Ludwig et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RNA-Guided Human Genome Engineering via Cas9
- (2013) P. Mali et al. SCIENCE
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering
- (2013) Thomas Gaj et al. TRENDS IN BIOTECHNOLOGY
- Gene gymnastics
- (2013) Lakshmi S Vijayachandran et al. Bioengineered
- A Synthetic Biology Framework for Programming Eukaryotic Transcription Functions
- (2012) Ahmad S. Khalil et al. CELL
- Encapsulated Cell Biodelivery of Nerve Growth Factor to the Basal Forebrain in Patients with Alzheimer’s Disease
- (2012) Maria Eriksdotter-Jönhagen et al. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
- A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
- (2012) M. Jinek et al. SCIENCE
- Application of MultiStem® Allogeneic Cells for Immunomodulatory Therapy: Clinical Progress and Pre-Clinical Challenges in Prophylaxis for Graft Versus Host Disease
- (2012) Bart Vaes et al. Frontiers in Immunology
- Long-Term Metabolic and Immunological Follow-Up of Nonimmunosuppressed Patients With Type 1 Diabetes Treated With Microencapsulated Islet Allografts: Four cases
- (2011) G. Basta et al. DIABETES CARE
- Use of allogeneic NK cells for cancer immunotherapy
- (2011) Melissa A Geller et al. Immunotherapy
- Immune complement activation is attenuated by surface nanotopography
- (2011) Mats Hulander et al. International Journal of Nanomedicine
- Human Artificial Chromosomes for Gene Delivery and the Development of Animal Models
- (2011) Yasuhiro Kazuki et al. MOLECULAR THERAPY
- In vivo genome editing restores haemostasis in a mouse model of haemophilia
- (2011) Hojun Li et al. NATURE
- Inducible Apoptosis as a Safety Switch for Adoptive Cell Therapy
- (2011) Antonio Di Stasi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Characterization of topographical effects on macrophage behavior in a foreign body response model
- (2010) Sulin Chen et al. BIOMATERIALS
- Ultralow-Fouling, Functionalizable, and Hydrolyzable Zwitterionic Materials and Their Derivatives for Biological Applications
- (2009) Shaoyi Jiang et al. ADVANCED MATERIALS
- Functional PEG–peptide hydrogels to modulate local inflammation inducedby the pro-inflammatory cytokine TNFα
- (2009) Chien-Chi Lin et al. BIOMATERIALS
- Safety and Viability of Microencapsulated Human Islets Transplanted Into Diabetic Humans
- (2009) B. E. Tuch et al. DIABETES CARE
- Targeted Migration of Mesenchymal Stem Cells Modified With CXCR4 Gene to Infarcted Myocardium Improves Cardiac Performance
- (2008) Zhaokang Cheng et al. MOLECULAR THERAPY
- Foreign body reaction to biomaterials
- (2008) James M. Anderson et al. SEMINARS IN IMMUNOLOGY
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