Immune-evasive human islet-like organoids ameliorate diabetes

Recapitulating endocrine cell clustering in culture promotes maturation of human stem-cell-derived β cells

(2019) Gopika G. Nair et al.   NATURE CELL BIOLOGY

Recovering Gene Interactions from Single-Cell Data Using Data Diffusion

(2018) David van Dijk et al.   CELL

Stem Cell Therapies for Treating Diabetes: Progress and Remaining Challenges

(2018) Julie B. Sneddon et al.   Cell Stem Cell

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Pancreas regeneration

(2018) Qiao Zhou et al.   NATURE

PDL1 is expressed in the islets of people with type 1 diabetes and is up-regulated by interferons-α and-γ via IRF1 induction

(2018) Maikel L. Colli et al.   EBioMedicine

All mixed up: defining roles for β-cell subtypes in mature islets

(2017) Jennifer S.E. Liu et al.   GENES & DEVELOPMENT

MHC matching improves engraftment of iPSC-derived neurons in non-human primates

(2017) Asuka Morizane et al.   Nature Communications

ERRγ Is Required for the Metabolic Maturation of Therapeutically Functional Glucose-Responsive β Cells

(2016) Eiji Yoshihara et al.   Cell Metabolism

Closing in on Mass Production of Mature Human Beta Cells

(2016) Timothy J. Kieffer   Cell Stem Cell

Identification of proliferative and mature β-cells in the islets of Langerhans

(2016) Erik Bader et al.   NATURE

PD-L1 Deficiency within Islets Reduces Allograft Survival in Mice

(2016) Dongxia Ma et al.   PLoS One

TGFβ-dependent expression of PD-1 and PD-L1 controls CD8+ T cell anergy in transplant tolerance

(2016) Marije Baas et al.   eLife

GOplot: an R package for visually combining expression data with functional analysis: Fig. 1.

(2015) Wencke Walter et al.   BIOINFORMATICS

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

(2015) Evan Z. Macosko et al.   CELL

Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro

(2015) H. A. Russ et al.   EMBO JOURNAL

Urocortin3 mediates somatostatin-dependent negative feedback control of insulin secretion

(2015) Talitha van der Meulen et al.   NATURE MEDICINE

Generation of Functional Human Pancreatic β Cells In Vitro

(2014) Felicia W. Pagliuca et al.   CELL

Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells

(2014) Alireza Rezania et al.   NATURE BIOTECHNOLOGY

Differentiated human stem cells resemble fetal, not adult, β cells

(2014) Sinisa Hrvatin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic Signaling in Fuel-Induced Insulin Secretion

(2013) Marc Prentki et al.   Cell Metabolism

Toward the Development of a Global Induced Pluripotent Stem Cell Library

(2013) Marc Turner et al.   Cell Stem Cell

Vascularized and functional human liver from an iPSC-derived organ bud transplant

(2013) Takanori Takebe et al.   NATURE

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Differential analysis of gene regulation at transcript resolution with RNA-seq

(2012) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Functional beta-cell maturation is marked by an increased glucose threshold and by expression of urocortin 3

(2012) Barak Blum et al.   NATURE BIOTECHNOLOGY

Urocortin 3 Marks Mature Human Primary and Embryonic Stem Cell-Derived Pancreatic Alpha and Beta Cells

(2012) Talitha van der Meulen et al.   PLoS One

Identification of novel transcripts in annotated genomes using RNA-Seq

(2011) A. Roberts et al.   BIOINFORMATICS

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Disruption of TBP-2 ameliorates insulin sensitivity and secretion without affecting obesity

(2010) Eiji Yoshihara et al.   Nature Communications

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

(2009) Shih-Min A. Huang et al.   NATURE

Protective Role of Programmed Death 1 Ligand 1 (PD-L1)in Nonobese Diabetic Mice: The Paradox in Transgenic Models

(2008) C.-J. Wang et al.   DIABETES