Designed protein logic to target cells with precise combinations of surface antigens
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Designed protein logic to target cells with precise combinations of surface antigens
Authors
Keywords
-
Journal
SCIENCE
Volume -, Issue -, Pages eaba6527
Publisher
American Association for the Advancement of Science (AAAS)
Online
2020-08-21
DOI
10.1126/science.aba6527
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- THEMIS-SHP1 Recruitment by 4-1BB Tunes LCK-Mediated Priming of Chimeric Antigen Receptor-Redirected T Cells
- (2020) Chuang Sun et al. CANCER CELL
- Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting
- (2019) Shivani Srivastava et al. CANCER CELL
- De novo design of bioactive protein switches
- (2019) Robert A. Langan et al. NATURE
- Universal Chimeric Antigen Receptors for Multiplexed and Logical Control of T Cell Responses
- (2018) Jang Hwan Cho et al. CELL
- A novel chimeric antigen receptor containing a JAK–STAT signaling domain mediates superior antitumor effects
- (2018) Yuki Kagoya et al. NATURE MEDICINE
- Enhanced tumor-targeting selectivity by modulating bispecific antibody binding affinity and format valence
- (2017) Yariv Mazor et al. Scientific Reports
- Precision Tumor Recognition by T Cells With Combinatorial Antigen-Sensing Circuits
- (2016) Kole T. Roybal et al. CELL
- Engineering Customized Cell Sensing and Response Behaviors Using Synthetic Notch Receptors
- (2016) Leonardo Morsut et al. CELL
- Balancing Selectivity and Efficacy of Bispecific Epidermal Growth Factor Receptor (EGFR) × c-MET Antibodies and Antibody-Drug Conjugates
- (2016) Carolin Sellmann et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability
- (2016) Adi Goldenzweig et al. MOLECULAR CELL
- De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity
- (2016) S. E. Boyken et al. SCIENCE
- T Cells Expressing CD19/CD20 Bispecific Chimeric Antigen Receptors Prevent Antigen Escape by Malignant B Cells
- (2016) E. Zah et al. Cancer Immunology Research
- α/β-Peptide Foldamers Targeting Intracellular Protein–Protein Interactions with Activity in Living Cells
- (2015) James W. Checco et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The Nonsignaling Extracellular Spacer Domain of Chimeric Antigen Receptors Is Decisive for In Vivo Antitumor Activity
- (2014) M. Hudecek et al. Cancer Immunology Research
- PD-1- and CTLA-4-Based Inhibitory Chimeric Antigen Receptors (iCARs) Divert Off-Target Immunotherapy Responses
- (2013) V. D. Fedorov et al. Science Translational Medicine
- Molecular Determinants of Bim(BH3) Peptide Binding to Pro-Survival Proteins
- (2012) Laura Delgado-Soler et al. Journal of Chemical Information and Modeling
- Combinatorial antigen recognition with balanced signaling promotes selective tumor eradication by engineered T cells
- (2012) Christopher C Kloss et al. NATURE BIOTECHNOLOGY
- A transgene-encoded cell surface polypeptide for selection, in vivo tracking, and ablation of engineered cells
- (2011) X. Wang et al. BLOOD
- DARPins Recognizing the Tumor-Associated Antigen EpCAM Selected by Phage and Ribosome Display and Engineered for Multivalency
- (2011) Nikolas Stefan et al. JOURNAL OF MOLECULAR BIOLOGY
- Daedalus: a robust, turnkey platform for rapid production of decigram quantities of active recombinant proteins in human cell lines using novel lentiviral vectors
- (2011) Ashok D. Bandaranayake et al. NUCLEIC ACIDS RESEARCH
- RosettaScripts: A Scripting Language Interface to the Rosetta Macromolecular Modeling Suite
- (2011) Sarel J. Fleishman et al. PLoS One
- XDS
- (2010) Wolfgang Kabsch ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Chemical synthesis of the mouse mitochondrial genome
- (2010) Daniel G Gibson et al. NATURE METHODS
- 4-1BB and CD28 Signaling Plays a Synergistic Role in Redirecting Umbilical Cord Blood T Cells Against B-Cell Malignancies
- (2009) Syam Tammana et al. HUMAN GENE THERAPY
- Efficient Selection of DARPins with Sub-nanomolar Affinities using SRP Phage Display
- (2008) Daniel Steiner et al. JOURNAL OF MOLECULAR BIOLOGY
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started