Targeting a Pre-existing Anti-transgene T Cell Response for Effective Gene Therapy of MPS-I in the Mouse Model of the Disease

Title
Targeting a Pre-existing Anti-transgene T Cell Response for Effective Gene Therapy of MPS-I in the Mouse Model of the Disease
Authors
Keywords
gene therapy, MPS-I, ERT, immune response, pre-existing immunity, lentiviral vector, HSC, depleting agents, fludarabine
Journal
MOLECULAR THERAPY
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2019-04-20
DOI
10.1016/j.ymthe.2019.04.014

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