Transposon-encoded CRISPR–Cas systems direct RNA-guided DNA integration

Evolution of Immune Systems From Viruses and Transposable Elements

(2019) Felix Broecker et al.   Frontiers in Microbiology

CRISPR-Cas systems are present predominantly on mobile genetic elements in Vibrio species

(2019) Nathan D. McDonald et al.   BMC GENOMICS

The Biology of CRISPR-Cas: Backward and Forward

(2018) Frank Hille et al.   CELL

Field-deployable viral diagnostics using CRISPR-Cas13

(2018) Cameron Myhrvold et al.   SCIENCE

Gene therapy comes of age

(2018) Cynthia E. Dunbar et al.   SCIENCE

Systematic discovery of antiphage defense systems in the microbial pangenome

(2018) Shany Doron et al.   SCIENCE

Determining the Specificity of Cascade Binding, Interference, and Primed Adaptation In Vivo in the Escherichia coli Type I-E CRISPR-Cas System

(2018) Lauren A. Cooper et al.   mBio

Transcriptional recording by CRISPR spacer acquisition from RNA

(2018) Florian Schmidt et al.   NATURE

Functionally diverse type V CRISPR-Cas systems

(2018) Winston X. Yan et al.   SCIENCE

Programmed DNA destruction by miniature CRISPR-Cas14 enzymes

(2018) Lucas B. Harrington et al.   SCIENCE

Mobile Genetic Elements and Evolution of CRISPR-Cas Systems: All the Way There and Back

(2017) Eugene V. Koonin et al.   Genome Biology and Evolution

Diversity and evolution of class 2 CRISPR–Cas systems

(2017) Sergey Shmakov et al.   NATURE REVIEWS MICROBIOLOGY

Recruitment of CRISPR-Cas systems by Tn7-like transposons

(2017) Joseph E. Peters et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inactivation of Pol θ and C-NHEJ eliminates off-target integration of exogenous DNA

(2017) Alex N. Zelensky et al.   Nature Communications

ISC, a Novel Group of Bacterial and Archaeal DNA Transposons That Encode Cas9 Homologs

(2015) Vladimir V. Kapitonov et al.   JOURNAL OF BACTERIOLOGY

The Turbulent Network Dynamics of Microbial Evolution and the Statistical Tree of Life

(2015) Eugene V. Koonin   JOURNAL OF MOLECULAR EVOLUTION

Two Distinct DNA Binding Modes Guide Dual Roles of a CRISPR-Cas Protein Complex

(2015) Timothy R. Blosser et al.   MOLECULAR CELL

Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems

(2015) Sergey Shmakov et al.   MOLECULAR CELL

Therapeutic genome editing: prospects and challenges

(2015) David Benjamin Turitz Cox et al.   NATURE MEDICINE

Horizontal gene transfer: building the web of life

(2015) Shannon M. Soucy et al.   NATURE REVIEWS GENETICS

Mechanism of foreign DNA recognition by a CRISPR RNA-guided surveillance complex from Pseudomonas aeruginosa

(2015) MaryClare F. Rollins et al.   NUCLEIC ACIDS RESEARCH

Directional R-Loop Formation by the CRISPR-Cas Surveillance Complex Cascade Provides Efficient Off-Target Site Rejection

(2015) Marius Rutkauskas et al.   Cell Reports

Molecular mechanisms of retroviral integration site selection

(2014) Mamuka Kvaratskhelia et al.   NUCLEIC ACIDS RESEARCH

Deciphering key features in protein structures with the new ENDscript server

(2014) Xavier Robert et al.   NUCLEIC ACIDS RESEARCH

The Tn7 transposition regulator TnsC interacts with the transposase subunit TnsB and target selector TnsD

(2014) K. Y. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Remarkable Mechanisms in Microbes to Resist Phage Infections

(2014) Ron L. Dy et al.   Annual Review of Virology

CRISPRTarget

(2013) Ambarish Biswas et al.   RNA Biology

Combining Quantitative Genetic Footprinting and Trait Enrichment Analysis to Identify Fitness Determinants of a Bacterial Pathogen

(2013) Travis J. Wiles et al.   PLoS Genetics

Recent developments in transposon-mediated gene therapy

(2012) Mario Di Matteo et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

Structures of the RNA-guided surveillance complex from a bacterial immune system

(2011) Blake Wiedenheft et al.   NATURE

RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions

(2011) B. Wiedenheft et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequence- and Structure-Specific RNA Processing by a CRISPR Endonuclease

(2010) Rachel E. Haurwitz et al.   SCIENCE

Transposition into Replicating DNA Occurs through Interaction with the Processivity Factor

(2009) Adam R. Parks et al.   CELL

Identifying Genetic Determinants Needed to Establish a Human Gut Symbiont in Its Habitat

(2009) Andrew L. Goodman et al.   Cell Host & Microbe

Tn-seq: high-throughput parallel sequencing for fitness and genetic interaction studies in microorganisms

(2009) Tim van Opijnen et al.   NATURE METHODS

Genomic islands are dynamic, ancient integrative elements in bacterial evolution

(2009) E. Fidelma Boyd et al.   TRENDS IN MICROBIOLOGY