Structural Plasticity of the Hippocampus in Neurodegenerative Diseases

Genetic Knockout of the Serotonin Reuptake Transporter Results in the Reduction of Dendritic Spines in In vitro Rat Cortical Neuronal Culture

(2021) Daniel Chaji et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Neuronal hibernation following hippocampal demyelination

(2021) Selva Baltan et al.   Acta Neuropathologica Communications

Regulation of hippocampal synaptic function by the metabolic hormone leptin: Implications for health and disease

(2021) Andrew Irving et al.   PROGRESS IN LIPID RESEARCH

Effects of imperatorin on apoptosis and synaptic plasticity in vascular dementia rats

(2021) Ying Huang et al.   Scientific Reports

Treatment with edaravone improves the structure and functional changes in the hippocampus after chronic cerebral hypoperfusion in rat

(2021) Gholam Hossein Meftahi et al.   BRAIN RESEARCH BULLETIN

SREBP-1c Deficiency Affects Hippocampal Micromorphometry and Hippocampus-Dependent Memory Ability in Mice

(2021) Mary Jasmin Ang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Alpha-Synuclein Pathology Coincides With Increased Number of Early Stage Neural Progenitors in the Adult Hippocampus

(2021) Hannah Bender et al.   Frontiers in Cell and Developmental Biology

Acute MPTP Treatment Impairs Dendritic Spine Density in the Mouse Hippocampus

(2021) Poornima D. E. Weerasinghe-Mudiyanselage et al.   Brain Sciences

Puerarin Alleviates Vascular Cognitive Impairment in Vascular Dementia Rats

(2021) Tiantian Zhu et al.   Frontiers in Behavioral Neuroscience

Donepezil attenuates vascular dementia in rats through increasing BDNF induced by reducing HDAC6 nuclear translocation

(2020) Wen-xuan Jian et al.   ACTA PHARMACOLOGICA SINICA

Synaptic Plasticity Forms and Functions

(2020) Jeffrey C. Magee et al.   Annual Review of Neuroscience

Rostral intralaminar thalamic deep brain stimulation ameliorates memory deficits and dendritic regression in β-amyloid-infused rats

(2020) Sheng-Tzung Tsai et al.   Brain Structure & Function

Memory-related process in physiological status and alzheimer’s disease

(2020) Seyedeh Nahid Fotuhi et al.   MOLECULAR BIOLOGY REPORTS

Safflower Yellow Improves the Synaptic Structural Plasticity by Ameliorating the Disorder of Glutamate Circulation in Aβ1-42-induced AD Model Rats

(2020) Jiawei Hou et al.   NEUROCHEMICAL RESEARCH

Synaptic plasticity in Alzheimer’s disease and healthy aging

(2020) Diana Marcela Cuestas Torres et al.   REVIEWS IN THE NEUROSCIENCES

The physiological roles of tau and Aβ: implications for Alzheimer’s disease pathology and therapeutics

(2020) Sarah A. Kent et al.   ACTA NEUROPATHOLOGICA

Muscone Ameliorates Synaptic Dysfunction and Cognitive Deficits in APP/PS1 Mice

(2020) Yi Liu et al.   JOURNAL OF ALZHEIMERS DISEASE

Hippocampal synaptic dysfunction in the SOD1G93A mouse model of Amyotrophic Lateral Sclerosis: Reversal by adenosine A2AR blockade

(2020) N. Rei et al.   NEUROPHARMACOLOGY

Age-related memory decline, dysfunction of the hippocampus and therapeutic opportunities

(2020) Lionel Dahan et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Hippocampal Synaptic Dysfunction in a Mouse Model of Huntington Disease Is Not Alleviated by Ceftriaxone Treatment

(2020) Crystal M. Wilkie et al.   eNeuro

Hippocampal connectivity in Amyotrophic Lateral Sclerosis (ALS): more than Papez circuit impairment

(2020) Francesca Trojsi et al.   Brain Imaging and Behavior

Deregulated expression of a longevity gene, Klotho, in the C9orf72 deletion mice with impaired synaptic plasticity and adult hippocampal neurogenesis

(2020) Wan Yun Ho et al.   Acta Neuropathologica Communications

Pharmacological Strategies to Improve Dendritic Spines in Alzheimer’s Disease

(2020) Miren Ettcheto et al.   JOURNAL OF ALZHEIMERS DISEASE

Apelin-13 prevents hippocampal synaptic plasticity impairment in Parkinsonism rats

(2020) Saeed Esmaeili-Mahani et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Heterogeneity within classical cell types is the rule: lessons from hippocampal pyramidal neurons

(2019) Mark S. Cembrowski et al.   NATURE REVIEWS NEUROSCIENCE

Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer’s disease

(2019) Elena P. Moreno-Jiménez et al.   NATURE MEDICINE

Alterations in Synaptic Function and Plasticity in Huntington Disease

(2019) Amy I. Smith‐Dijak et al.   JOURNAL OF NEUROCHEMISTRY

Alpha-synuclein (αSyn) preformed fibrils induce endogenous αSyn aggregation, compromise synaptic activity and enhance synapse loss in cultured excitatory hippocampal neurons

(2019) Qihui Wu et al.   JOURNAL OF NEUROSCIENCE

Honokiol Attenuates the Memory Impairments, Oxidative Stress, Neuroinflammation, and GSK-3β Activation in Vascular Dementia Rats

(2019) Si Guo et al.   JOURNAL OF ALZHEIMERS DISEASE

Transcranial Magneto-Acoustic Stimulation Improves Neuroplasticity in Hippocampus of Parkinson’s Disease Model Mice

(2019) Yuexiang Wang et al.   Neurotherapeutics

Dendritic spines: Revisiting the physiological role

(2019) Saravana Babu Chidambaram et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

The Onset and Progression of Hippocampal Synaptic Plasticity Deficits in the Q175FDN Mouse Model of Huntington Disease

(2019) Jade G. Quirion et al.   Frontiers in Cellular Neuroscience

Ageing as a risk factor for neurodegenerative disease

(2019) Yujun Hou et al.   Nature Reviews Neurology

Hippocampal pathology in Amyotrophic Lateral Sclerosis: selective vulnerability of subfields and their associated projections

(2019) Foteini Christidi et al.   NEUROBIOLOGY OF AGING

Effects of autophagy on synaptic-plasticity-related protein expression in the hippocampus CA1 of a rat model of vascular dementia

(2019) Bin Liu et al.   NEUROSCIENCE LETTERS

Pleiotropic Mitochondria: The Influence of Mitochondria on Neuronal Development and Disease

(2019) Vidhya Rangaraju et al.   JOURNAL OF NEUROSCIENCE

Emotion dysregulation in multiple sclerosis: Impact on symptoms of depression and anxiety

(2019) R.S. Prakash et al.   Multiple Sclerosis and Related Disorders

Scene construction impairments in frontotemporal dementia: Evidence for a primary hippocampal contribution

(2019) Nikki-Anne Wilson et al.   NEUROPSYCHOLOGIA

Evidence for altered dendritic spine compartmentalization in Alzheimer’s disease and functional effects in a mouse model

(2018) Alexandre Androuin et al.   ACTA NEUROPATHOLOGICA

Altered function of neuronal L-type calcium channels in ageing and neuroinflammation: Implications in age-related synaptic dysfunction and cognitive decline

(2018) Sheeja Navakkode et al.   AGEING RESEARCH REVIEWS

Altering cortical input unmasks synaptic phenotypes in the YAC128 cortico-striatal co-culture model of Huntington disease

(2018) Mandi E. Schmidt et al.   BMC BIOLOGY

Structural and functional papez circuit integrity in amyotrophic lateral sclerosis

(2018) Ana Paula Arantes Bueno et al.   Brain Imaging and Behavior

Physical exercise reserved amyloid-beta induced brain dysfunctions by regulating hippocampal neurogenesis and inflammatory response via MAPK signaling

(2018) Li-na Sun et al.   BRAIN RESEARCH

Excessive Glutamate Stimulation Impairs ACE2 Activity Through ADAM17-Mediated Shedding in Cultured Cortical Neurons

(2018) Jiaxi Xu et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Huntington’s disease: novel therapeutic perspectives hanging in the balance

(2018) Ana Saavedra et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Dendritic spine pathology and thrombospondin-1 deficits in Down syndrome

(2018) Maria D. Torres et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hippocampal Subfield Volumetry: Differential Pattern of Atrophy in Different Forms of Genetic Frontotemporal Dementia

(2018) Martina Bocchetta et al.   JOURNAL OF ALZHEIMERS DISEASE

Ling-Yang-Gou-Teng-decoction prevents vascular dementia through inhibiting oxidative stress induced neurovascular coupling dysfunction

(2018) Xin Zhao et al.   JOURNAL OF ETHNOPHARMACOLOGY

Deciphering the microstructure of hippocampal subfields with in vivo DTI and NODDI: Applications to experimental multiple sclerosis

(2018) Amandine Crombe et al.   NEUROIMAGE

Clearance of Amyloid Beta and Tau in Alzheimer’s Disease: from Mechanisms to Therapy

(2018) Shu-Hui Xin et al.   NEUROTOXICITY RESEARCH

The Clinical and Radiological Spectrum of Hippocampal Pathology in Amyotrophic Lateral Sclerosis

(2018) Foteini Christidi et al.   Frontiers in Neurology

α-Synuclein fibril-induced paradoxical structural and functional defects in hippocampal neurons

(2018) Jessica M. Froula et al.   Acta Neuropathologica Communications

Adenosine A2A Receptors Facilitate Synaptic NMDA Currents in CA1 Pyramidal Neurons

(2018) Francisco Mouro et al.   BRITISH JOURNAL OF PHARMACOLOGY

miRNA-34c Overexpression Causes Dendritic Loss and Memory Decline

(2018) Yu-Chia Kao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The hippocampus in multiple sclerosis

(2018) Maria A Rocca et al.   LANCET NEUROLOGY

Dendritic spine remodeling accompanies Alzheimer’s disease pathology and genetic susceptibility in cognitively normal aging

(2018) Benjamin D. Boros et al.   NEUROBIOLOGY OF AGING

Global, regional, and national burden of Alzheimer's disease and other dementias, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

(2018) Emma Nichols et al.   LANCET NEUROLOGY

Global, regional, and national burden of Parkinson's disease, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

(2018) E. Ray Dorsey et al.   LANCET NEUROLOGY

Synaptic, Mitochondrial, and Lysosomal Dysfunction in Parkinson’s Disease

(2018) Maria Nguyen et al.   TRENDS IN NEUROSCIENCES

Regulation of Hippocampal Synaptic Function by the Metabolic Hormone, Leptin: Implications for Health and Neurodegenerative Disease

(2018) Gemma McGregor et al.   Frontiers in Cellular Neuroscience

Modulation of AMPA receptor surface diffusion restores hippocampal plasticity and memory in Huntington’s disease models

(2018) Hongyu Zhang et al.   Nature Communications

NSCs promote hippocampal neurogenesis, metabolic changes and synaptogenesis in APP/PS1 transgenic mice

(2017) Wei Zhang et al.   HIPPOCAMPUS

Mitochondrial dynamics in neuronal injury, development and plasticity

(2017) Kyle H. Flippo et al.   JOURNAL OF CELL SCIENCE

Endocannabinoid-Specific Impairment in Synaptic Plasticity in Striatum of Huntington's Disease Mouse Model

(2017) Marja D. Sepers et al.   JOURNAL OF NEUROSCIENCE

Cortactin Is a Regulator of Activity-Dependent Synaptic Plasticity Controlled by Wingless

(2017) Daniel Alicea et al.   JOURNAL OF NEUROSCIENCE

Tau-dependent suppression of adult neurogenesis in the stressed hippocampus

(2017) C Dioli et al.   MOLECULAR PSYCHIATRY

Dopamine D1 receptor subtype mediates acute stress-induced dendritic growth in excitatory neurons of the medial prefrontal cortex and contributes to suppression of stress susceptibility in mice

(2017) R Shinohara et al.   MOLECULAR PSYCHIATRY

Role of G Protein-Coupled Receptors in the Regulation of Structural Plasticity and Cognitive Function

(2017) Crystal Leung et al.   MOLECULES

New insights into the burden and costs of multiple sclerosis in Europe

(2017) Gisela Kobelt et al.   Multiple Sclerosis Journal

Amyloid-β and tau complexity — towards improved biomarkers and targeted therapies

(2017) Juan Carlos Polanco et al.   Nature Reviews Neurology

Memory-related white matter tract integrity in amyotrophic lateral sclerosis: an advanced neuroimaging and neuropsychological study

(2017) Foteini Christidi et al.   NEUROBIOLOGY OF AGING

Exercise improves recognition memory and synaptic plasticity in the prefrontal cortex for rats modelling vascular dementia

(2017) Juntao Dong et al.   NEUROLOGICAL RESEARCH

The effects of aging in the hippocampus and cognitive decline

(2017) Luis E.B. Bettio et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Changes in epigenetic markers, DNMT1 and HDAC1/2, in the adult mouse hippocampus after cranial irradiation

(2017) Sohi Kang et al.   NEUROSCIENCE LETTERS

Stellate cells drive maturation of the entorhinal-hippocampal circuit

(2017) Flavio Donato et al.   SCIENCE

The aminoestrogen prolame increases recognition memory and hippocampal neuronal spine density in aged mice

(2017) Alfonso Diaz et al.   SYNAPSE

MicroRNA-195 prevents dendritic degeneration and neuron death in rats following chronic brain hypoperfusion

(2017) Xin Chen et al.   Cell Death & Disease

Pyk2 modulates hippocampal excitatory synapses and contributes to cognitive deficits in a Huntington’s disease model

(2017) Albert Giralt et al.   Nature Communications

TDP-43 misexpression causes defects in dendritic growth

(2017) Josiah J. Herzog et al.   Scientific Reports

New insights into the burden and costs of multiple sclerosis in Europe

(2017) Gisela Kobelt et al.   Multiple Sclerosis Journal

Noradrenergic Modulation of Cognition in Health and Disease

(2017) Olga Borodovitsyna et al.   NEURAL PLASTICITY

Motor Areas Show Altered Dendritic Structure in an Amyotrophic Lateral Sclerosis Mouse Model

(2017) Matthew J. Fogarty et al.   Frontiers in Neuroscience

Amyotrophic lateral sclerosis

(2017) Orla Hardiman et al.   Nature Reviews Disease Primers

Neurite dispersion: a new marker of multiple sclerosis spinal cord pathology?

(2017) Francesco Grussu et al.   Annals of Clinical and Translational Neurology

Protective Effect of 17β-Estradiol Upon Hippocampal Spine Density and Cognitive Function in an Animal Model of Vascular Dementia

(2017) Ying Zhu et al.   Scientific Reports

Edaravone injection reverses learning and memory deficits in a rat model of vascular dementia

(2016) Xu Li et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Neuroinflammation impairs adaptive structural plasticity of dendritic spines in a preclinical model of Alzheimer’s disease

(2016) Chengyu Zou et al.   ACTA NEUROPATHOLOGICA

Dendritic Spine Pathology in Neurodegenerative Diseases

(2016) Jochen Herms et al.   Annual Review of Pathology-Mechanisms of Disease

Prostaglandin E2 EP2 activation reduces memory decline in R6/1 mouse model of Huntington's disease by the induction of BDNF-dependent synaptic plasticity

(2016) Marta Anglada-Huguet et al.   NEUROBIOLOGY OF DISEASE

Severely impaired hippocampal neurogenesis associates with an early serotonergic deficit in a BAC α-synuclein transgenic rat model of Parkinson's disease

(2016) Zacharias Kohl et al.   NEUROBIOLOGY OF DISEASE

Possible involvement of hippocampal immediate–early genes in contextual fear memory deficit induced by cranial irradiation

(2016) Yeonghoon Son et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Structural and functional neuroplasticity in human learning of spatial routes

(2016) Timothy A. Keller et al.   NEUROIMAGE

Purine nucleosides in neuroregeneration and neuroprotection

(2016) Filipa F. Ribeiro et al.   NEUROPHARMACOLOGY

Scanning Ultrasound (SUS) Causes No Changes to Neuronal Excitability and Prevents Age-Related Reductions in Hippocampal CA1 Dendritic Structure in Wild-Type Mice

(2016) Robert John Hatch et al.   PLoS One

Neuronal changes after chronic high blood pressure in animal models and its implication for vascular dementia

(2016) Gonzalo Flores et al.   SYNAPSE

Early Impairment of Synaptic and Intrinsic Excitability in Mice Expressing ALS/Dementia-Linked Mutant UBQLN2

(2016) Daniel Radzicki et al.   Frontiers in Cellular Neuroscience

Neuronal Circuitry Mechanisms Regulating Adult Mammalian Neurogenesis

(2016) Juan Song et al.   Cold Spring Harbor Perspectives in Biology

Non-motor symptoms and quality of life in patients with Parkinson’s disease in Northeastern Mexico

(2015) Ingrid Estrada-Bellmann et al.   ACTA NEUROLOGICA BELGICA

Viral gene transfer of APPsα rescues synaptic failure in an Alzheimer’s disease mouse model

(2015) Romain Fol et al.   ACTA NEUROPATHOLOGICA

Complement C1q-C3-associated synaptic changes in multiple sclerosis hippocampus

(2015) Iliana Michailidou et al.   ANNALS OF NEUROLOGY

Effects of repetitive transcranial magnetic stimulation on synaptic plasticity and apoptosis in vascular dementia rats

(2015) Hui-Yun Yang et al.   BEHAVIOURAL BRAIN RESEARCH

Synaptic plasticity and experimental autoimmune encephalomyelitis: implications for multiple sclerosis

(2015) Massimiliano Di Filippo et al.   BRAIN RESEARCH

Sialylation regulates brain structure and function

(2015) Seung-Wan Yoo et al.   FASEB JOURNAL

AMPK activation protects from neuronal dysfunction and vulnerability across nematode, cellular and mouse models of Huntington's disease

(2015) Rafael P. Vázquez-Manrique et al.   HUMAN MOLECULAR GENETICS

Fingolimod (FTY720) enhances hippocampal synaptic plasticity and memory in Huntington's disease by preventing p75NTRup-regulation and astrocyte-mediated inflammation

(2015) Andrés Miguez et al.   HUMAN MOLECULAR GENETICS

Sitagliptin attenuated brain damage and cognitive impairment in mice with chronic cerebral hypo-perfusion through suppressing oxidative stress and inflammatory reaction

(2015) Tzu-Hsien Tsai et al.   JOURNAL OF HYPERTENSION

Activation of Cdk5/p25 and tau phosphorylation following chronic brain hypoperfusion in rats involves microRNA-195 down-regulation

(2015) Li-Hua Sun et al.   JOURNAL OF NEUROCHEMISTRY

Serotonergic dysfunction in the A53T alpha-synuclein mouse model of Parkinson's disease

(2015) Janina Deusser et al.   JOURNAL OF NEUROCHEMISTRY

The cognitive profile of ALS: a systematic review and meta-analysis update

(2015) Emma Beeldman et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Neuronal Store-Operated Calcium Entry and Mushroom Spine Loss in Amyloid Precursor Protein Knock-In Mouse Model of Alzheimer's Disease

(2015) H. Zhang et al.   JOURNAL OF NEUROSCIENCE

RBM3 mediates structural plasticity and protective effects of cooling in neurodegeneration

(2015) Diego Peretti et al.   NATURE

A Cellular Perspective on Brain Energy Metabolism and Functional Imaging

(2015) Pierre J. Magistretti et al.   NEURON

Hippocampal function is compromised in an animal model of multiple sclerosis

(2015) T. Novkovic et al.   NEUROSCIENCE

Hippocampal plasticity during the progression of Alzheimer’s disease

(2015) E.J. Mufson et al.   NEUROSCIENCE

Structural imaging of hippocampal subfields in healthy aging and Alzheimer’s disease

(2015) Robin de Flores et al.   NEUROSCIENCE

Levodopa-induced plasticity: a double-edged sword in Parkinson's disease?

(2015) Paolo Calabresi et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Structural Plasticity of Dendritic Spines Requires GSK3α and GSK3β

(2015) Iwona A. Cymerman et al.   PLoS One

Cuprizone decreases intermediate and late-stage progenitor cells in hippocampal neurogenesis of rats in a framework of 28-day oral dose toxicity study

(2015) Hajime Abe et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Alpha-Synuclein affects neurite morphology, autophagy, vesicle transport and axonal degeneration in CNS neurons

(2015) J C Koch et al.   Cell Death & Disease

Modulation of Hippocampal Neural Plasticity by Glucose-Related Signaling

(2015) Marco Mainardi et al.   NEURAL PLASTICITY

TDP-43 regulatesβ-adducin(Add2) transcript stability

(2015) Luisa Costessi et al.   RNA Biology

Tau aggregation and its interplay with amyloid-β

(2014) Rebecca M. Nisbet et al.   ACTA NEUROPATHOLOGICA

Alzheimer disease: Epidemiology, diagnostic criteria, risk factors and biomarkers

(2014) Christiane Reitz et al.   BIOCHEMICAL PHARMACOLOGY

Regional differences in acute corticosterone-induced dendritic remodeling in the rat brain and their behavioral consequences

(2014) Hyejin Kim et al.   BMC NEUROSCIENCE

The structure and function of actin cytoskeleton in mature glutamatergic dendritic spines

(2014) Alba Bellot et al.   BRAIN RESEARCH

Piracetam Ameliorated Oxygen and Glucose Deprivation-Induced Injury in Rat Cortical Neurons Via Inhibition of Oxidative Stress, Excitatory Amino Acids Release and P53/Bax

(2014) Zhi He et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

l-DOPA reverses the impairment of Dentate Gyrus LTD in experimental parkinsonism via β-adrenergic receptors

(2014) Valentina Pendolino et al.   EXPERIMENTAL NEUROLOGY

Short- and long-term functional plasticity of white matter induced by oligodendrocyte depolarization in the hippocampus

(2014) Yoshihiko Yamazaki et al.   GLIA

The diagnosis of multiple sclerosis and the various related demyelinating syndromes: A critical review

(2014) Dimitrios Karussis   JOURNAL OF AUTOIMMUNITY

Neurotrophin receptor p75NTR mediates Huntington’s disease–associated synaptic and memory dysfunction

(2014) Verónica Brito et al.   JOURNAL OF CLINICAL INVESTIGATION

Early fear memory defects are associated with altered synaptic plasticity and molecular architecture in the TgCRND8 Alzheimer's disease mouse model

(2014) John W. Steele et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Hippocampal Plasticity during the Peripartum Period: Influence of Sex Steroids, Stress and Ageing

(2014) L. A. M. Galea et al.   JOURNAL OF NEUROENDOCRINOLOGY

Mitochondria Modify Exercise-Induced Development of Stem Cell-Derived Neurons in the Adult Brain

(2014) K. Steib et al.   JOURNAL OF NEUROSCIENCE

The link between multiple sclerosis and depression

(2014) Anthony Feinstein et al.   Nature Reviews Neurology

Autophagy activation aggravates neuronal injury in the hippocampus of vascular dementia rats

(2014) Bin Liu et al.   Neural Regeneration Research

Axonal Transport of TDP-43 mRNA Granules Is Impaired by ALS-Causing Mutations

(2014) Nael H. Alami et al.   NEURON

Role of ERK signaling in activity-dependent modifications of histone proteins

(2014) Alessandro Ciccarelli et al.   NEUROPHARMACOLOGY

Low-grade inflammation disrupts structural plasticity in the human brain

(2014) C. Szabó et al.   NEUROSCIENCE

Dendritic Spines: The Locus of Structural and Functional Plasticity

(2014) Carlo Sala et al.   PHYSIOLOGICAL REVIEWS

Striatal Synaptic Dysfunction and Hippocampal Plasticity Deficits in the Hu97/18 Mouse Model of Huntington Disease

(2014) Karolina Kolodziejczyk et al.   PLoS One

Dendritic spinopathy in transgenic mice expressing ALS/dementia-linked mutantUBQLN2

(2014) George H. Gorrie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wnt signaling in the nervous system and in Alzheimer's disease

(2014) N. C. Inestrosa et al.   Journal of Molecular Cell Biology

Pathological α-synuclein impairs adult-born granule cell development and functional integration in the olfactory bulb

(2014) Johanna Neuner et al.   Nature Communications

Adult Hippocampal Neurogenesis in Parkinson’s Disease: Impact on Neuronal Survival and Plasticity

(2014) Martin Regensburger et al.   NEURAL PLASTICITY

Stages of pTDP-43 pathology in amyotrophic lateral sclerosis

(2013) Johannes Brettschneider et al.   ANNALS OF NEUROLOGY

Brain-Derived Neurotrophic Factor in Neuroimmunology: Lessons Learned from Multiple Sclerosis Patients and Experimental Autoimmune Encephalomyelitis Models

(2013) Fred Lühder et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Structural plasticity of dendritic spines: The underlying mechanisms and its dysregulation in brain disorders

(2013) Kwok-On Lai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Neuronal cytoskeleton in synaptic plasticity and regeneration

(2013) Phillip R. Gordon-Weeks et al.   JOURNAL OF NEUROCHEMISTRY

An electrophysiologic approach to quantify impaired synaptic transmission and plasticity in experimental autoimmune encephalomyelitis

(2013) Nora Prochnow et al.   JOURNAL OF NEUROIMMUNOLOGY

MicroRNA-195 Protects Against Dementia Induced by Chronic Brain Hypoperfusion via Its Anti-Amyloidogenic Effect in Rats

(2013) J. Ai et al.   JOURNAL OF NEUROSCIENCE

Pathology and disease mechanisms in different stages of multiple sclerosis

(2013) Hans Lassmann   JOURNAL OF THE NEUROLOGICAL SCIENCES

New experimental and clinical links between the hippocampus and the dopaminergic system in Parkinson's disease

(2013) Paolo Calabresi et al.   LANCET NEUROLOGY

Prostaglandin E2 EP1 Receptor Antagonist Improves Motor Deficits and Rescues Memory Decline in R6/1 Mouse Model of Huntington's Disease

(2013) Marta Anglada-Huguet et al.   MOLECULAR NEUROBIOLOGY

Impact of N-tau on adult hippocampal neurogenesis, anxiety, and memory

(2013) Andrea Pristerà et al.   NEUROBIOLOGY OF AGING

Effect of mild cognitive impairment on the patterns of neural activity in early Parkinson's disease

(2013) Atsuko Nagano-Saito et al.   NEUROBIOLOGY OF AGING

Effects of central and peripheral inflammation on hippocampal synaptic plasticity

(2013) Massimiliano Di Filippo et al.   NEUROBIOLOGY OF DISEASE

Embryonic alteration of motoneuronal morphology induces hyperexcitability in the mouse model of amyotrophic lateral sclerosis

(2013) Elodie Martin et al.   NEUROBIOLOGY OF DISEASE

Interleukin-1β Promotes Long-Term Potentiation in Patients with Multiple Sclerosis

(2013) Francesco Mori et al.   NEUROMOLECULAR MEDICINE

Synaptic gene dysregulation within hippocampal CA1 pyramidal neurons in mild cognitive impairment

(2013) Scott E. Counts et al.   NEUROPHARMACOLOGY

Treatment of Cognitive, Psychiatric, and Affective Disorders Associated with Parkinson’s Disease

(2013) Barbara Connolly et al.   Neurotherapeutics

Synaptic plasticity in multiple sclerosis and in experimental autoimmune encephalomyelitis

(2013) R. Nistico et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Inflammation Subverts Hippocampal Synaptic Plasticity in Experimental Multiple Sclerosis

(2013) Robert Nisticò et al.   PLoS One

Short- and Long-Term Effects of LRRK2 on Axon and Dendrite Growth

(2013) Bryan Sepulveda et al.   PLoS One

Neuroinflammation and Neuronal Loss Precede Aβ Plaque Deposition in the hAPP-J20 Mouse Model of Alzheimer’s Disease

(2013) Amanda L. Wright et al.   PLoS One

Acute Physiological Stress Promotes Clustering of Synaptic Markers and Alters Spine Morphology in the Hippocampus

(2013) Veronica Sebastian et al.   PLoS One

Memory and synaptic deficits in Hip14/DHHC17 knockout mice

(2013) A. J. Milnerwood et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A  induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss

(2013) M. Talantova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Huntington's disease: underlying molecular mechanisms and emerging concepts

(2013) John Labbadia et al.   TRENDS IN BIOCHEMICAL SCIENCES

Developmental neuroplasticity and the origin of neurodegenerative diseases

(2013) Andrea T. U. Schaefers et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

Activity-dependent regulation of dendritic growth and maintenance by glycogen synthase kinase 3β

(2013) Yanfang Rui et al.   Nature Communications

A cholinergic trigger drives learning-induced plasticity at hippocampal synapses

(2013) Dai Mitsushima et al.   Nature Communications

 -Synuclein in Parkinson's Disease

(2013) L. Stefanis   Cold Spring Harbor Perspectives in Medicine

Sustained remission from depressive-like behavior depends on hippocampal neurogenesis

(2013) A Mateus-Pinheiro et al.   Translational Psychiatry

Mechanisms underlying the impairment of hippocampal long-term potentiation and memory in experimental Parkinson’s disease

(2012) Cinzia Costa et al.   BRAIN

Dopamine D1/D5 Receptors Mediate Informational Saliency that Promotes Persistent Hippocampal Long-Term Plasticity

(2012) N. Hansen et al.   CEREBRAL CORTEX

Cognitive dysfunction and depression in Parkinson’s disease: what can be learned from rodent models?

(2012) Hanna S. Lindgren et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Characterization of dopamine D1 and D2 receptor-expressing neurons in the mouse hippocampus

(2012) Giuseppe Gangarossa et al.   HIPPOCAMPUS

Cognitive Impairment in Parkinson Disease

(2012) Iracema Leroi et al.   JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY

The dendritic tree and brain disorders

(2012) Vaishali A. Kulkarni et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Roles of AMP-activated Protein Kinase in Alzheimer’s Disease

(2012) Zhiyou Cai et al.   NEUROMOLECULAR MEDICINE

Dendritic spine changes associated with normal aging

(2012) D.L. Dickstein et al.   NEUROSCIENCE

Inflammation-Mediated Memory Dysfunction and Effects of a Ketogenic Diet in a Murine Model of Multiple Sclerosis

(2012) Do Young Kim et al.   PLoS One

Quetiapine enhances oligodendrocyte regeneration and myelin repair after cuprizone-induced demyelination

(2012) Yanbo Zhang et al.   SCHIZOPHRENIA RESEARCH

Monoacylglycerol Lipase Is a Therapeutic Target for Alzheimer's Disease

(2012) Rongqing Chen et al.   Cell Reports

Hippocampal Neurogenesis, Cognitive Deficits and Affective Disorder in Huntington's Disease

(2012) Mark I. Ransome et al.   NEURAL PLASTICITY

Immune System in the Brain: A Modulatory Role on Dendritic Spine Morphophysiology?

(2012) Oscar Kurt Bitzer-Quintero et al.   NEURAL PLASTICITY

Cognitive Impairment in Huntington Disease: Diagnosis and Treatment

(2011) Jane S. Paulsen   Current Neurology and Neuroscience Reports

Phenotypic signatures of genetic frontotemporal dementia

(2011) Jonathan D. Rohrer et al.   CURRENT OPINION IN NEUROLOGY

Synapse formation on adult-born hippocampal neurons

(2011) Nicolas Toni et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease

(2011) U. P. Shirendeb et al.   HUMAN MOLECULAR GENETICS

Dopamine in the hippocampus is cleared by the norepinephrine transporter

(2011) Anders Borgkvist et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

BDNF-Induced Increase of PSD-95 in Dendritic Spines Requires Dynamic Microtubule Invasions

(2011) X. Hu et al.   JOURNAL OF NEUROSCIENCE

Role of serotonergic 1A receptor dysfunction in depression associated with Parkinson's disease

(2011) Benedicte Ballanger et al.   MOVEMENT DISORDERS

Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43

(2011) Magdalini Polymenidou et al.   NATURE NEUROSCIENCE

Dendritic spine pathology in neuropsychiatric disorders

(2011) Peter Penzes et al.   NATURE NEUROSCIENCE

Hippocampal dysregulation of synaptic plasticity-associated proteins with age-related cognitive decline

(2011) Heather D. VanGuilder et al.   NEUROBIOLOGY OF DISEASE

Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death

(2011) Laura A. Volpicelli-Daley et al.   NEURON

Pathophysiology of Huntington's disease: time-dependent alterations in synaptic and receptor function

(2011) L.A. Raymond et al.   NEUROSCIENCE

Vascular Cognitive Impairment: Disease Mechanisms and Therapeutic Implications

(2011) Deborah A. Levine et al.   Neurotherapeutics

Plasticity of local GABAergic interneurons drives olfactory habituation

(2011) S. Das et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Light-Induced Structural and Functional Plasticity in Drosophila Larval Visual System

(2011) Q. Yuan et al.   SCIENCE

The Cell Biology of Synaptic Plasticity

(2011) V. M. Ho et al.   SCIENCE

Spines, Plasticity, and Cognition in Alzheimer's Model Mice

(2011) Tara Spires-Jones et al.   NEURAL PLASTICITY

Demyelination causes synaptic alterations in hippocampi from multiple sclerosis patients

(2010) Ranjan Dutta et al.   ANNALS OF NEUROLOGY

Fatigue in Parkinson's disease is linked to striatal and limbic serotonergic dysfunction

(2010) N. Pavese et al.   BRAIN

Dendritic vulnerability in neurodegenerative disease: insights from analyses of cortical pyramidal neurons in transgenic mouse models

(2010) Jennifer I. Luebke et al.   Brain Structure & Function

Postsynaptic Alteration of NR2A Subunit and Defective Autophosphorylation of alphaCaMKII at Threonine-286 Contribute to Abnormal Plasticity and Morphology of Upper Motor Neurons in Presymptomatic SOD1G93A Mice, a Murine Model for Amyotrophic Lateral Sclerosis

(2010) A. Spalloni et al.   CEREBRAL CORTEX

Transient elevation of adult hippocampal neurogenesis after dopamine depletion

(2010) June-Hee Park et al.   EXPERIMENTAL NEUROLOGY

Role of the SNK-SPAR pathway in the development of Alzheimer's disease

(2010) Xiaoyang Gong et al.   IUBMB LIFE

Actin in dendritic spines: connecting dynamics to function

(2010) Pirta Hotulainen et al.   JOURNAL OF CELL BIOLOGY

Synaptic Activity Controls Dendritic Spine Morphology by Modulating eEF2-Dependent BDNF Synthesis

(2010) C. Verpelli et al.   JOURNAL OF NEUROSCIENCE

Cerebrospinal fluid and plasma biomarkers in Alzheimer disease

(2010) Kaj Blennow et al.   Nature Reviews Neurology

Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice

(2010) B. Winner et al.   NEUROBIOLOGY OF DISEASE

Mild cognitive impairment in prediagnosed Huntington disease

(2010) K. Duff et al.   NEUROLOGY

Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration

(2010) Brian R. Hoover et al.   NEURON

A comparative study of Lrrk2 function in primary neuronal cultures

(2010) Justus C. Dächsel et al.   PARKINSONISM & RELATED DISORDERS

Molecular Mechanisms and Potential Therapeutical Targets in Huntington's Disease

(2010) Chiara Zuccato et al.   PHYSIOLOGICAL REVIEWS

Short-Term Environmental Enrichment Enhances Adult Neurogenesis, Vascular Network and Dendritic Complexity in the Hippocampus of Type 1 Diabetic Mice

(2010) Juan Beauquis et al.   PLoS One

Early synaptic pathophysiology in neurodegeneration: insights from Huntington's disease

(2010) Austen J. Milnerwood et al.   TRENDS IN NEUROSCIENCES

Cholinergic deficiency involved in vascular dementia: possible mechanism and strategy of treatment

(2009) Juan Wang et al.   ACTA PHARMACOLOGICA SINICA

Structure and function of dendritic spines within the hippocampus

(2009) Oliver von Bohlen und Halbach   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

Glutamate and Neurotrophic Factors in Neuronal Plasticity and Disease

(2009) Mark P. Mattson   Annals of the New York Academy of Sciences

Structural Plasticity and Hippocampal Function

(2009) Benedetta Leuner et al.   Annual Review of Psychology

Impaired mitochondrial trafficking in Huntington's disease

(2009) Xiao-Jiang Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Hippocampal tau pathology is related to neuroanatomical connections: an ageing population-based study

(2009) G. Lace et al.   BRAIN

Imbalance between GABAergic and Glutamatergic Transmission Impairs Adult Neurogenesis in an Animal Model of Alzheimer's Disease

(2009) Binggui Sun et al.   Cell Stem Cell

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

(2009) Clifford R Jack et al.   LANCET NEUROLOGY

The PRIAMO study: A multicenter assessment of nonmotor symptoms and their impact on quality of life in Parkinson's disease

(2009) Paolo Barone et al.   MOVEMENT DISORDERS

The effects of chronic glucocorticoid exposure on dendritic length, synapse numbers and glial volume in animal models: Implications for hippocampal volume reductions in depression

(2009) Despina A. Tata et al.   PHYSIOLOGY & BEHAVIOR

Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice

(2009) D. A. Simmons et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Balancing Structure and Function at Hippocampal Dendritic Spines

(2008) Jennifer N Bourne et al.   Annual Review of Neuroscience

Cognitive changes in multiple sclerosis

(2008) Maria Pia Amato et al.   Expert Review of Neurotherapeutics

Abnormal medial prefrontal cortex connectivity and defective fear extinction in the presymptomatic G93A SOD1 mouse model of ALS

(2008) C. Sgobio et al.   GENES BRAIN AND BEHAVIOR

Neonatal Neuronal Circuitry Shows Hyperexcitable Disturbance in a Mouse Model of the Adult-Onset Neurodegenerative Disease Amyotrophic Lateral Sclerosis

(2008) B. van Zundert et al.   JOURNAL OF NEUROSCIENCE

Cognitive impairment in multiple sclerosis

(2008) Nancy D Chiaravalloti et al.   LANCET NEUROLOGY

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE

Pyramidal neurons: dendritic structure and synaptic integration

(2008) Nelson Spruston   NATURE REVIEWS NEUROSCIENCE

A Role for Local Calcium Signaling in Rapid Synaptic Partner Selection by Dendritic Filopodia

(2008) Christian Lohmann et al.   NEURON

TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis

(2008) J. Sreedharan et al.   SCIENCE

Detection of Huntington's disease decades before diagnosis: the Predict-HD study

(2007) J S Paulsen et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Be smart, exercise your heart: exercise effects on brain and cognition

(2007) Charles H. Hillman et al.   NATURE REVIEWS NEUROSCIENCE

Gene–environment interactions modulating cognitive function and molecular correlates of synaptic plasticity in Huntington’s disease transgenic mice

(2007) Jess Nithianantharajah et al.   NEUROBIOLOGY OF DISEASE