Altering cortical input unmasks synaptic phenotypes in the YAC128 cortico-striatal co-culture model of Huntington disease

The sigma-1 receptor mediates the beneficial effects of pridopidine in a mouse model of Huntington disease

(2017) Daniel Ryskamp et al.   NEUROBIOLOGY OF DISEASE

Synaptopathic mechanisms of neurodegeneration and dementia: Insights from Huntington’s disease

(2017) Shiraz Tyebji et al.   PROGRESS IN NEUROBIOLOGY

Influence of cortical synaptic input on striatal neuronal dendritic arborization and sensitivity to excitotoxicity in corticostriatal coculture

(2016) Caodu Buren et al.   JOURNAL OF NEUROPHYSIOLOGY

Enhanced Store-Operated Calcium Entry Leads to Striatal Synaptic Loss in a Huntington's Disease Mouse Model

(2016) J. Wu et al.   JOURNAL OF NEUROSCIENCE

Optimising Golgi–Cox staining for use with perfusion-fixed brain tissue validated in the zQ175 mouse model of Huntington's disease

(2016) Zubeyde Bayram-Weston et al.   JOURNAL OF NEUROSCIENCE METHODS

Impaired development of cortico-striatal synaptic connectivity in a cell culture model of Huntington's disease

(2016) Caodu Buren et al.   NEUROBIOLOGY OF DISEASE

Synaptic scaling up in medium spiny neurons of aged BACHD mice: A slow-progression model of Huntington's disease

(2016) Anne B. Rocher et al.   NEUROBIOLOGY OF DISEASE

Differential changes in thalamic and cortical excitatory synapses onto striatal spiny projection neurons in a Huntington disease mouse model

(2016) Karolina Kolodziejczyk et al.   NEUROBIOLOGY OF DISEASE

Cortical Efferents Lacking Mutant huntingtin Improve Striatal Neuronal Activity and Behavior in a Conditional Mouse Model of Huntington's Disease

(2015) A. M. Estrada-Sanchez et al.   JOURNAL OF NEUROSCIENCE

Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's disease

(2014) Nan Wang et al.   NATURE MEDICINE

Fluorescent labeling of dendritic spines in cell cultures with the carbocyanine dye “DiI”

(2014) Connie Cheng et al.   Frontiers in Neuroanatomy

Dendritic Spine Instability Leads to Progressive Neocortical Spine Loss in a Mouse Model of Huntington's Disease

(2013) R. P. Murmu et al.   JOURNAL OF NEUROSCIENCE

Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models

(2013) Sonia Marco et al.   NATURE MEDICINE

Role of cerebral cortex in the neuropathology of Huntington's disease

(2013) Ana M. Estrada-Sánchez et al.   Frontiers in Neural Circuits

Striatal atrophy and dendritic alterations in a knock-in mouse model of Huntington's disease

(2012) Renata P. Lerner et al.   BRAIN RESEARCH BULLETIN

Marked differences in neurochemistry and aggregates despite similar behavioural and neuropathological features of Huntington disease in the full-length BACHD and YAC128 mice

(2012) M. A. Pouladi et al.   HUMAN MOLECULAR GENETICS

Opposing Roles of Synaptic and Extrasynaptic NMDA Receptor Signaling in Cocultured Striatal and Cortical Neurons

(2012) A. M. Kaufman et al.   JOURNAL OF NEUROSCIENCE

Mitigation of augmented extrasynaptic NMDAR signaling and apoptosis in cortico-striatal co-cultures from Huntington's disease mice

(2012) Austen J. Milnerwood et al.   NEUROBIOLOGY OF DISEASE

Differential Electrophysiological Changes in Striatal Output Neurons in Huntington's Disease

(2011) V. M. Andre et al.   JOURNAL OF NEUROSCIENCE

Pathophysiology of Huntington's disease: time-dependent alterations in synaptic and receptor function

(2011) L.A. Raymond et al.   NEUROSCIENCE

Alterations in Striatal Synaptic Transmission are Consistent across Genetic Mouse Models of Huntington's Disease

(2010) Damian M Cummings et al.   ASN Neuro

Early Increase in Extrasynaptic NMDA Receptor Signaling and Expression Contributes to Phenotype Onset in Huntington's Disease Mice

(2010) Austen J. Milnerwood et al.   NEURON

Modeling Brain Reserve: Experience-Dependent Neuronal Plasticity in Healthy and Huntington's Disease Transgenic Mice

(2009) Jess Nithianantharajah et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Mouse models of Huntington's disease and methodological considerations for therapeutic trials

(2009) Robert J. Ferrante   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Age-Dependent Alterations of Corticostriatal Activity in the YAC128 Mouse Model of Huntington Disease

(2009) P. R. Joshi et al.   JOURNAL OF NEUROSCIENCE