Regulation of hippocampal synaptic function by the metabolic hormone leptin: Implications for health and disease

Regulation of NMDA glutamate receptor functions by the GluN2 subunits

(2020) Marta Vieira et al.   JOURNAL OF NEUROCHEMISTRY

Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

(2020) Stephen C. Cunnane et al.   NATURE REVIEWS DRUG DISCOVERY

Leptin regulates exon-specific transcription of the Bdnf gene via epigenetic modifications mediated by an AKT/p300 HAT cascade

(2020) Chen Li et al.   MOLECULAR PSYCHIATRY

Leptin enhances adult neurogenesis and reduces pathological features in a transgenic mouse model of Alzheimer’s disease

(2020) Michele Longoni Calió et al.   NEUROBIOLOGY OF DISEASE

Activation of estrogen receptor α induces a novel form of long‐term potentiation at hippocampal temporoammonic‐CA1 synapses

(2019) Leigh Clements et al.   BRITISH JOURNAL OF PHARMACOLOGY

Leptin Controls Glutamatergic Synaptogenesis and NMDA-Receptor Trafficking via Fyn Kinase Regulation of NR2B

(2019) Tyler Bland et al.   ENDOCRINOLOGY

Age-dependent regulation of excitatory synaptic transmission at hippocampal temporoammonic-CA1 synapses by leptin

(2018) Gemma McGregor et al.   NEUROBIOLOGY OF AGING

The adipocyte hormone leptin sets the emergence of hippocampal inhibition in mice

(2018) Camille Dumon et al.   eLife

Canonical JAK-STAT signaling is pivotal for long-term depression at adult hippocampal temporoammonic-CA1 synapses

(2017) Gemma McGregor et al.   FASEB JOURNAL

Leptin Regulation of Synaptic Function at Hippocampal TA-CA1 and SC-CA1 Synapses: Implications for Health and Disease

(2017) Gemma McGregor et al.   NEUROCHEMICAL RESEARCH

Amyloid-β Decreases Cell-Surface AMPA Receptors by Increasing Intracellular Calcium and Phosphorylation of GluR2

(2017) Shi-Jie Liu et al.   JOURNAL OF ALZHEIMERS DISEASE

A Leptin Fragment Mirrors the Cognitive Enhancing and Neuroprotective Actions of Leptin

(2016) Yasaman Malekizadeh et al.   CEREBRAL CORTEX

Altered Intrinsic Pyramidal Neuron Properties and Pathway-Specific Synaptic Dysfunction Underlie Aberrant Hippocampal Network Function in a Mouse Model of Tauopathy

(2016) C. A. Booth et al.   JOURNAL OF NEUROSCIENCE

17β estradiol recruits GluN2B-containing NMDARs and ERK during induction of long-term potentiation at temporoammonic-CA1 synapses

(2015) Caroline C. Smith et al.   HIPPOCAMPUS

Leptin attenuates the detrimental effects of β-amyloid on spatial memory and hippocampal later-phase long term potentiation in rats

(2015) Jia-qing Tong et al.   HORMONES AND BEHAVIOR

Complementary Roles of Human Hippocampal Subfields in Differentiation and Integration of Spatial Context

(2015) Jared Stokes et al.   JOURNAL OF COGNITIVE NEUROSCIENCE

Early Structural and Functional Defects in Synapses and Myelinated Axons in Stratum Lacunosum Moleculare in Two Preclinical Models for Tauopathy

(2014) Hervé Maurin et al.   PLoS One

Leptin potentiates GABAergic synaptic transmission in the developing rodent hippocampus

(2014) Damien Guimond et al.   Frontiers in Cellular Neuroscience

Leptin and ghrelin prevent hippocampal dysfunction induced by Aβ oligomers

(2013) I. Martins et al.   NEUROSCIENCE

Leptin prevents hippocampal synaptic disruption and neuronal cell death induced by amyloid β

(2012) Gayle H. Doherty et al.   NEUROBIOLOGY OF AGING

The JAK/STAT Pathway Is Involved in Synaptic Plasticity

(2012) Céline S. Nicolas et al.   NEURON

Bidirectional metabolic regulation of neurocognitive function

(2011) Alexis M. Stranahan et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

NMDA receptor subunit composition determines the polarity of leptin-induced synaptic plasticity

(2011) Peter R. Moult et al.   NEUROPHARMACOLOGY

Leptin Regulates AMPA Receptor Trafficking via PTEN Inhibition

(2010) P. R. Moult et al.   JOURNAL OF NEUROSCIENCE

Ultrahigh-resolution microstructural diffusion tensor imaging reveals perforant path degradation in aged humans in vivo

(2010) Michael A. Yassa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Leptin-dependent Phosphorylation of PTEN Mediates Actin Restructuring and Activation of ATP-sensitive K+Channels

(2009) Ke Ning et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Soluble Oligomers of Amyloid β Protein Facilitate Hippocampal Long-Term Depression by Disrupting Neuronal Glutamate Uptake

(2009) Shaomin Li et al.   NEURON

Bi-directional modulation of fast inhibitory synaptic transmission by leptin

(2008) Natasha Solovyova et al.   JOURNAL OF NEUROCHEMISTRY

Leptin reverses long-term potentiation at hippocampal CA1 synapses

(2008) Peter R. Moult et al.   JOURNAL OF NEUROCHEMISTRY

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE

Impaired Spatial Representation in CA1 after Lesion of Direct Input from Entorhinal Cortex

(2008) Vegard Heimly Brun et al.   NEURON

Leptin inhibits 4-aminopyridine– and pentylenetetrazole-induced seizures and AMPAR-mediated synaptic transmission in rodents

(2007) Lin Xu et al.   JOURNAL OF CLINICAL INVESTIGATION