Safflower Yellow Improves the Synaptic Structural Plasticity by Ameliorating the Disorder of Glutamate Circulation in Aβ1-42-induced AD Model Rats

Neuroprotection of hydroxysafflor yellow A in experimental cerebral ischemia/reperfusion injury via metabolic inhibition of phenylalanine and mitochondrial biogenesis

(2019) Suning Chen et al.   Molecular Medicine Reports

Safflower yellow attenuates learning and memory deficits in amyloid β-induced Alzheimer’s disease rats by inhibiting neuroglia cell activation and inflammatory signaling pathways

(2019) Lu Zhang et al.   METABOLIC BRAIN DISEASE

Effects of safflower yellow on beta-amyloid deposition and activation of astrocytes in the brain of APP/PS1 transgenic mice

(2018) Xiao-meng Shi et al.   BIOMEDICINE & PHARMACOTHERAPY

Protective cerebrovascular effects of hydroxysafflor yellow A (HSYA) on ischemic stroke

(2018) Yang Sun et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The effect of phloretin on synaptic proteins and adult hippocampal neurogenesis in Aβ (1-42)-injected male Wistar rats

(2018) Priya Ghumatkar et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Estradiol rapidly increases GluA2-mushroom spines and decreases GluA2-filopodia spines in hippocampus CA1

(2017) Jorge A. Avila et al.   HIPPOCAMPUS

Learning and memory improvement and neuroprotection of Gardenia jasminoides (Fructus gardenia) extract on ischemic brain injury rats

(2017) Haiyan Zhang et al.   JOURNAL OF ETHNOPHARMACOLOGY

The malleable brain: plasticity of neural circuits and behavior - a review from students to students

(2017) Natascha Schaefer et al.   JOURNAL OF NEUROCHEMISTRY

The Structure of the ZMYND8/Drebrin Complex Suggests a Cytoplasmic Sequestering Mechanism of ZMYND8 by Drebrin

(2017) Ningning Yao et al.   STRUCTURE

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

Decreased synaptic proteins in neuronal exosomes of frontotemporal dementia and Alzheimer’s disease

(2016) Edward J. Goetzl et al.   FASEB JOURNAL

Safflower yellow ameliorates cognition deficits and reduces tau phosphorylation in APP/PS1 transgenic mice

(2016) Ying-ying Ruan et al.   METABOLIC BRAIN DISEASE

Therapeutic strategies for Alzheimer's disease in clinical trials

(2016) Justyna Godyń et al.   Pharmacological Reports

Safflower yellow reduces lipid peroxidation, neuropathology, tau phosphorylation and ameliorates amyloid β-induced impairment of learning and memory in rats

(2015) Qin Ma et al.   BIOMEDICINE & PHARMACOTHERAPY

The motor learning induces plastic changes in dendritic spines of Purkinje cells from the neocerebellar cortex of the rat

(2015) David González-Tapia et al.   RESTORATIVE NEUROLOGY AND NEUROSCIENCE

Protection of TGF-β1 against Neuroinflammation and Neurodegeneration in Aβ1–42-Induced Alzheimer’s Disease Model Rats

(2015) Jia-Hui Chen et al.   PLoS One

Alzheimer disease: Epidemiology, diagnostic criteria, risk factors and biomarkers

(2014) Christiane Reitz et al.   BIOCHEMICAL PHARMACOLOGY

Hydroxy-safflor yellow A attenuates Aβ1-42-induced inflammation by modulating the JAK2/STAT3/NF-κB pathway

(2014) Zuo-hui Zhang et al.   BRAIN RESEARCH

Activity-Dependent p25 Generation Regulates Synaptic Plasticity and Aβ-Induced Cognitive Impairment

(2014) Jinsoo Seo et al.   CELL

TGF-β1 Protection against Aβ1–42-Induced Neuroinflammation and Neurodegeneration in Rats

(2014) Wei-Xing Shen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hydroxysafflor Yellow A Protects Against Cerebral Ischemia–Reperfusion Injury by Anti-apoptotic Effect Through PI3K/Akt/GSK3β Pathway in Rat

(2013) Lin Chen et al.   NEUROCHEMICAL RESEARCH

A  induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss

(2013) M. Talantova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydroxysafflor Yellow A Ameliorates Homocysteine-Induced Alzheimer-Like Pathologic Dysfunction and Memory/Synaptic Disorder

(2013) Ya-Qin Lu et al.   REJUVENATION RESEARCH

Amyloid Precursor Protein Processing and Alzheimer's Disease

(2011) Richard J. O'Brien et al.   Annual Review of Neuroscience

Is Alzheimer's Disease a Result of Presynaptic Failure? - Synaptic Dysfunctions Induced by Oligomeric β-Amyloid

(2011) Volker Nimmrich et al.   REVIEWS IN THE NEUROSCIENCES

Neuroprotective Effects of Hydroxysafflor Yellow A Against Excitotoxic Neuronal Death Partially Through Down-Regulation of NR2B-Containing NMDA Receptors

(2010) Q. Yang et al.   NEUROCHEMICAL RESEARCH

Enhanced cognitive performance of dopamine D3 receptor “knock-out” mice in the step-through passive-avoidance test: Assessing the role of the endocannabinoid/endovanilloid systems

(2010) Vincenzo Micale et al.   PHARMACOLOGICAL RESEARCH

Experience-dependent structural synaptic plasticity in the mammalian brain

(2009) Anthony Holtmaat et al.   NATURE REVIEWS NEUROSCIENCE

Soluble Oligomers of Amyloid β Protein Facilitate Hippocampal Long-Term Depression by Disrupting Neuronal Glutamate Uptake

(2009) Shaomin Li et al.   NEURON