Adult Hippocampal Neurogenesis in Parkinson’s Disease: Impact on Neuronal Survival and Plasticity

Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo

(2014) Edward Rockenstein et al.   BRAIN

Temporally selective contextual encoding in the dentate gyrus of the hippocampus

(2014) L.M. Rangel et al.   Nature Communications

Surveillance, Phagocytosis, and Inflammation: How Never-Resting Microglia Influence Adult Hippocampal Neurogenesis

(2014) Amanda Sierra et al.   NEURAL PLASTICITY

The effects of exercise on cognition in Parkinson’s disease: a systematic review

(2014) Danielle K Murray et al.   Translational Neurodegeneration

α-Synucleinopathy associated with G51D SNCA mutation: a link between Parkinson’s disease and multiple system atrophy?

(2013) Aoife P. Kiely et al.   ACTA NEUROPATHOLOGICA

Neuropathology of stress

(2013) Paul J. Lucassen et al.   ACTA NEUROPATHOLOGICA

Axonopathy in an α-Synuclein Transgenic Model of Lewy Body Disease Is Associated with Extensive Accumulation of C-Terminal–Truncated α-Synuclein

(2013) Dora Games et al.   AMERICAN JOURNAL OF PATHOLOGY

Structural Changes in Hippocampal Subfields in Major Depressive Disorder: A High-Field Magnetic Resonance Imaging Study

(2013) Yushan Huang et al.   BIOLOGICAL PSYCHIATRY

A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats

(2013) Silke Nuber et al.   BRAIN

Increased Amoeboid Microglial Density in the Olfactory Bulb of Parkinson's and Alzheimer's Patients

(2013) Karlijn J. Doorn et al.   BRAIN PATHOLOGY

Dynamics of Hippocampal Neurogenesis in Adult Humans

(2013) Kirsty L. Spalding et al.   CELL

α-Synuclein Oligomers Impair Neuronal Microtubule-Kinesin Interplay

(2013) Iryna Prots et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Serotonin Is Required for Exercise-Induced Adult Hippocampal Neurogenesis

(2013) F. Klempin et al.   JOURNAL OF NEUROSCIENCE

New experimental and clinical links between the hippocampus and the dopaminergic system in Parkinson's disease

(2013) Paolo Calabresi et al.   LANCET NEUROLOGY

In vivo imaging of adult human hippocampal neurogenesis: progress, pitfalls and promise

(2013) N F Ho et al.   MOLECULAR PSYCHIATRY

Parkinson's disease dementia: convergence of α-synuclein, tau and amyloid-β pathologies

(2013) David J. Irwin et al.   NATURE REVIEWS NEUROSCIENCE

Glial A30P alpha-synuclein pathology segregates neurogenesis from anxiety-related behavior in conditional transgenic mice

(2013) Franz Marxreiter et al.   NEUROBIOLOGY OF DISEASE

A novel  -synuclein missense mutation in Parkinson disease

(2013) C. Proukakis et al.   NEUROLOGY

Review: The future of cell therapies and brain repair: Parkinson's disease leads the way

(2013) G. H. Petit et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Hippocampal Granule Neuron Number and Dentate Gyrus Volume in Antidepressant-Treated and Untreated Major Depression

(2013) Maura Boldrini et al.   NEUROPSYCHOPHARMACOLOGY

Mutant LRRK2 Elicits Calcium Imbalance and Depletion of Dendritic Mitochondria in Neurons

(2012) Salvatore J. Cherra et al.   AMERICAN JOURNAL OF PATHOLOGY

Quantitative evaluation of the human subventricular zone

(2012) G. U. Hoglinger et al.   BRAIN

Reply: Quantitative evaluation of the human subventricular zone

(2012) S. A. van den Berge et al.   BRAIN

Neurogenesis, inflammation and behavior

(2012) Rachel A. Kohman et al.   BRAIN BEHAVIOR AND IMMUNITY

Neurogenic potential of progenitor cells isolated from postmortem human Parkinsonian brains

(2012) Shanshan Wang et al.   BRAIN RESEARCH

Enhanced dendritogenesis and axogenesis in hippocampal neuroblasts of LRRK2 knockout mice

(2012) Marie Paus et al.   BRAIN RESEARCH

Fluoxetine rescues impaired hippocampal neurogenesis in a transgenic A53T synuclein mouse model

(2012) Zacharias Kohl et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Fluoxetine ameliorates behavioral and neuropathological deficits in a transgenic model mouse of α-synucleinopathy

(2012) Kiren Ubhi et al.   EXPERIMENTAL NEUROLOGY

α-Synuclein Induces Alterations in Adult Neurogenesis in Parkinson Disease Models via p53-mediated Repression of Notch1

(2012) Paula Desplats et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of  -Synuclein in Adult Neurogenesis and Neuronal Maturation in the Dentate Gyrus

(2012) B. Winner et al.   JOURNAL OF NEUROSCIENCE

Microglia Modulate Hippocampal Neural Precursor Activity in Response to Exercise and Aging

(2012) J. Vukovic et al.   JOURNAL OF NEUROSCIENCE

The many faces of α-synuclein: from structure and toxicity to therapeutic target

(2012) Hilal A. Lashuel et al.   NATURE REVIEWS NEUROSCIENCE

Hippocampal abnormalities and memory deficits in Parkinson disease: A multimodal imaging study

(2012) G. A. Carlesimo et al.   NEUROLOGY

Impaired olfactory bulb neurogenesis depends on the presence of human wild-type alpha-synuclein

(2012) V.E.L. May et al.   NEUROSCIENCE

Reduced Proliferation in the Adult Mouse Subventricular Zone Increases Survival of Olfactory Bulb Interneurons

(2012) Yi Sui et al.   PLoS One

Non-Motor Symptoms in Patients with Parkinson’s Disease – Correlations with Inflammatory Cytokines in Serum

(2012) Daniel Lindqvist et al.   PLoS One

Emerging roles of microglial activation and non-motor symptoms in Parkinson's disease

(2012) Karlijn J. Doorn et al.   PROGRESS IN NEUROBIOLOGY

Depression and Hippocampal Neurogenesis: A Road to Remission?

(2012) A. J. Eisch et al.   SCIENCE

Increased dopaminergic cells and protein aggregates in the olfactory bulb of patients with neurodegenerative disorders

(2011) Iñaki-Carril Mundiñano et al.   ACTA NEUROPATHOLOGICA

Neuropathology underlying clinical variability in patients with synucleinopathies

(2011) Glenda M. Halliday et al.   ACTA NEUROPATHOLOGICA

The proliferative capacity of the subventricular zone is maintained in the parkinsonian brain

(2011) Simone A. van den Berge et al.   BRAIN

Disease Modification in Parkinsonʼs Disease

(2011) Claire Henchcliffe et al.   DRUGS & AGING

In vivo imaging of adult neurogenesis

(2011) Sebastien Couillard-Despres et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Synapse formation on adult-born hippocampal neurons

(2011) Nicolas Toni et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Neurodegenerative disease and adult neurogenesis

(2011) Beate Winner et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Parkinson’s disease risk score: moving to a premotor diagnosis

(2011) Jürgen Winkler et al.   JOURNAL OF NEUROLOGY

Dopaminergic Modulation of Cortical Inputs during Maturation of Adult-Born Dentate Granule Cells

(2011) Y. Mu et al.   JOURNAL OF NEUROSCIENCE

Role of serotonergic 1A receptor dysfunction in depression associated with Parkinson's disease

(2011) Benedicte Ballanger et al.   MOVEMENT DISORDERS

Corridors of migrating neurons in the human brain and their decline during infancy

(2011) Nader Sanai et al.   NATURE

Passive Immunization Reduces Behavioral and Neuropathological Deficits in an Alpha-Synuclein Transgenic Model of Lewy Body Disease

(2011) Eliezer Masliah et al.   PLoS One

In vivo demonstration that  -synuclein oligomers are toxic

(2011) B. Winner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Is neurogenesis relevant in depression and in the mechanism of antidepressant drug action? A critical review

(2011) Siu W. Tang et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

The synaptic pathology of α-synuclein aggregation in dementia with Lewy bodies, Parkinson’s disease and Parkinson’s disease dementia

(2010) Walter J. Schulz-Schaeffer   ACTA NEUROPATHOLOGICA

Mutant α-synuclein and aging reduce neurogenesis in the acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson’s disease

(2010) Jun Peng et al.   AGING CELL

Longterm quiescent cells in the aged human subventricular neurogenic system specifically express GFAP-δ

(2010) Simone A. Van Den Berge et al.   AGING CELL

Notch1 signaling related hippocampal neurogenesis in adult poststroke depression rats: a valid index for an efficient combined citalopram and WAY100635 pharmacotherapy

(2010) Shao-Hua Wang et al.   BEHAVIOURAL PHARMACOLOGY

Olfactory dysfunction, central cholinergic integrity and cognitive impairment in Parkinson's disease

(2010) N. I. Bohnen et al.   BRAIN

Fatigue in Parkinson's disease is linked to striatal and limbic serotonergic dysfunction

(2010) N. Pavese et al.   BRAIN

Mechanisms Underlying Inflammation in Neurodegeneration

(2010) Christopher K. Glass et al.   CELL

Discovery of a Proneurogenic, Neuroprotective Chemical

(2010) Andrew A. Pieper et al.   CELL

Direct Transfer of α-Synuclein from Neuron to Astroglia Causes Inflammatory Responses in Synucleinopathies

(2010) He-Jin Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Pathologic Cascade Leading to Synaptic Dysfunction in  -Synuclein-Induced Neurodegeneration

(2010) D. A. Scott et al.   JOURNAL OF NEUROSCIENCE

Neuropsychological and clinical heterogeneity of cognitive impairment and dementia in patients with Parkinson's disease

(2010) Angie A Kehagia et al.   LANCET NEUROLOGY

In Vivo RNAi-Mediated α-Synuclein Silencing Induces Nigrostriatal Degeneration

(2010) Oleg S Gorbatyuk et al.   MOLECULAR THERAPY

What are the most important nonmotor symptoms in patients with Parkinson's disease and are we missing them?

(2010) David A. Gallagher et al.   MOVEMENT DISORDERS

The effect of drug treatment on neurogenesis in Parkinson's disease

(2010) Sean S. O'Sullivan et al.   MOVEMENT DISORDERS

Prion-like transmission of protein aggregates in neurodegenerative diseases

(2010) Patrik Brundin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice

(2010) H.L. Melrose et al.   NEUROBIOLOGY OF DISEASE

Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice

(2010) B. Winner et al.   NEUROBIOLOGY OF DISEASE

Genetic Animal Models of Parkinson's Disease

(2010) Ted M. Dawson et al.   NEURON

Changes in adult olfactory bulb neurogenesis in mice expressing the A30P mutant form of alpha-synuclein

(2009) Franz Marxreiter et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Dopamine receptor activation promotes adult neurogenesis in an acute Parkinson model

(2009) Beate Winner et al.   EXPERIMENTAL NEUROLOGY

Seeding induced by α-synuclein oligomers provides evidence for spreading of α-synuclein pathology

(2009) Karin M. Danzer et al.   JOURNAL OF NEUROCHEMISTRY

Dopaminergic Lesion Enhances Growth Factor-Induced Striatal Neuroblast Migration

(2009) Beate Winner et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

The PRIAMO study: A multicenter assessment of nonmotor symptoms and their impact on quality of life in Parkinson's disease

(2009) Paolo Barone et al.   MOVEMENT DISORDERS

Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease

(2009) Wataru Satake et al.   NATURE GENETICS

Genome-wide association study reveals genetic risk underlying Parkinson's disease

(2009) Javier Simón-Sánchez et al.   NATURE GENETICS

Medical records documentation of constipation preceding Parkinson disease: A case-control study

(2009) R. Savica et al.   NEUROLOGY

Autoimmune disease and risk for Parkinson disease: A population-based case-control study

(2009) K. Rugbjerg et al.   NEUROLOGY

Diagnosis and the premotor phase of Parkinson disease

(2009) E. Tolosa et al.   NEUROLOGY

Non-motor features of Parkinson's disease: depression and dementia

(2009) Heinz Reichmann et al.   PARKINSONISM & RELATED DISORDERS

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of  -synuclein

(2009) P. Desplats et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dopamine-induced proliferation of adult neural precursor cells in the mammalian subventricular zone is mediated through EGF

(2009) G. C. O'Keeffe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Functional Role for Adult Hippocampal Neurogenesis in Spatial Pattern Separation

(2009) C. D. Clelland et al.   SCIENCE

Review: Cellular repair strategies in Parkinson's disease

(2009) Beate Winner et al.   Therapeutic Advances in Neurological Disorders

Peripheral cytokines profile in Parkinson’s disease

(2008) M. Reale et al.   BRAIN BEHAVIOR AND IMMUNITY

Mechanisms and Functional Implications of Adult Neurogenesis

(2008) Chunmei Zhao et al.   CELL

Neurodegeneration and Motor Dysfunction in a Conditional Model of Parkinson's Disease

(2008) S. Nuber et al.   JOURNAL OF NEUROSCIENCE

 -Synuclein Alters Notch-1 Expression and Neurogenesis in Mouse Embryonic Stem Cells and in the Hippocampus of Transgenic Mice

(2008) L. Crews et al.   JOURNAL OF NEUROSCIENCE

Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study

(2008) Daniel G Healy et al.   LANCET NEUROLOGY

Transplanted dopaminergic neurons develop PD pathologic changes: A second case report

(2008) Jeffrey H. Kordower et al.   MOVEMENT DISORDERS

The prodromal phase of sporadic Parkinson's disease: Does it exist and if so how long is it?

(2008) Christopher H. Hawkes   MOVEMENT DISORDERS

Dopamine neurons implanted into people with Parkinson's disease survive without pathology for 14 years

(2008) Ivar Mendez et al.   NATURE MEDICINE

Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

(2008) Jia-Yi Li et al.   NATURE MEDICINE

Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease

(2008) Jeffrey H Kordower et al.   NATURE MEDICINE

Fibroblast growth factor 2 enhances striatal and nigral neurogenesis in the acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease

(2008) J. Peng et al.   NEUROSCIENCE

Brain inflammation and adult neurogenesis: The dual role of microglia

(2008) C.T. Ekdahl et al.   NEUROSCIENCE

Selective hyposmia in Parkinson disease: Association with hippocampal dopamine activity

(2008) Nicolaas I. Bohnen et al.   NEUROSCIENCE LETTERS

Neurotoxicity of MPTP to migrating neuroblasts: Studies in acute and subacute mouse models of Parkinson's disease

(2008) Xi Jun He et al.   NEUROTOXICOLOGY

Association of olfactory dysfunction with risk for future Parkinson's disease

(2007) G. Webster Ross et al.   ANNALS OF NEUROLOGY

Mutant α-synuclein exacerbates age-related decrease of neurogenesis

(2007) Beate Winner et al.   NEUROBIOLOGY OF AGING

Increased progenitor cell proliferation and astrogenesis in the partial progressive 6-hydroxydopamine model of Parkinson’s disease

(2007) P.M. Aponso et al.   NEUROSCIENCE