Sialylation regulates brain structure and function

The Challenge and Promise of Glycomics

(2014) Richard D. Cummings et al.   CHEMISTRY & BIOLOGY

Genetic evidence that Nkx2.2 and Pdgfra are major determinants of the timing of oligodendrocyte differentiation in the developing CNS

(2014) Q. Zhu et al.   DEVELOPMENT

Neuronal Expression of GalNAc Transferase Is Sufficient to Prevent the Age-Related Neurodegenerative Phenotype of Complex Ganglioside-Deficient Mice

(2014) Denggao Yao et al.   JOURNAL OF NEUROSCIENCE

Sialic Acids in the Brain: Gangliosides and Polysialic Acid in Nervous System Development, Stability, Disease, and Regeneration

(2014) Ronald L. Schnaar et al.   PHYSIOLOGICAL REVIEWS

Alteration of Ganglioside Biosynthesis Responsible for Complex Hereditary Spastic Paraplegia

(2013) Amir Boukhris et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Cutaneous dyspigmentation in patients with ganglioside GM3 synthase deficiency

(2013) Heng Wang et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Mutations in B4GALNT1 (GM2 synthase) underlie a new disorder of ganglioside biosynthesis

(2013) Gaurav V. Harlalka et al.   BRAIN

A mutation in a ganglioside biosynthetic enzyme, ST3GAL5, results in salt & pepper syndrome, a neurocutaneous disorder with altered glycolipid and glycoprotein glycosylation

(2013) Luigi Boccuto et al.   HUMAN MOLECULAR GENETICS

Three Mechanisms Assemble Central Nervous System Nodes of Ranvier

(2013) Keiichiro Susuki et al.   NEURON

West syndrome caused byST3Gal-IIIdeficiency

(2012) Simon Edvardson et al.   EPILEPSIA

Refractory epilepsy and mitochondrial dysfunction due to GM3 synthase deficiency

(2012) Konstantina Fragaki et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Biosynthesis of the major brain gangliosides GD1a and GT1b

(2012) Elizabeth R Sturgill et al.   GLYCOBIOLOGY

Longitudinal assessment of gait abnormalities following penetrating ballistic-like brain injury in rats

(2012) Andrea Mountney et al.   JOURNAL OF NEUROSCIENCE METHODS

ST3GAL3 Mutations Impair the Development of Higher Cognitive Functions

(2011) Hao Hu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Evolutionary Forces Shaping the Golgi Glycosylation Machinery: Why Cell Surface Glycans Are Universal to Living Cells

(2011) A. Varki   Cold Spring Harbor Perspectives in Biology

Glycomics Hits the Big Time

(2010) Gerald W. Hart et al.   CELL

Current trends in the structure-activity relationships of sialyltransferases

(2010) M. Audry et al.   GLYCOBIOLOGY

CXCR2-positive neutrophils are essential for cuprizone-induced demyelination: relevance to multiple sclerosis

(2010) LiPing Liu et al.   NATURE NEUROSCIENCE

The Sialome—Far More Than the Sum of Its Parts

(2010) Miriam Cohen et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Brain gangliosides in axon-myelin stability and axon regeneration

(2009) Ronald L. Schnaar   FEBS LETTERS

Reduced motor and sensory functions and emotional response in GM3-only mice: Emergence from early stage of life and exacerbation with aging

(2008) Orie Tajima et al.   BEHAVIOURAL BRAIN RESEARCH

Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency

(2008) Siming Shen et al.   NATURE NEUROSCIENCE