Regulation of Hippocampal Synaptic Function by the Metabolic Hormone, Leptin: Implications for Health and Neurodegenerative Disease

Age-dependent regulation of excitatory synaptic transmission at hippocampal temporoammonic-CA1 synapses by leptin

(2018) Gemma McGregor et al.   NEUROBIOLOGY OF AGING

Leptin and ghrelin: Sewing metabolism onto neurodegeneration

(2018) Paola de Candia et al.   NEUROPHARMACOLOGY

Ghrelin Ameliorates Cognitive Dysfunction and Neurodegeneration in Intrahippocampal Amyloid-β1-42 Oligomer-Injected Mice

(2018) Minho Moon et al.   JOURNAL OF ALZHEIMERS DISEASE

Diet-induced obesity alters memory consolidation in female rats

(2017) P. Zanini et al.   PHYSIOLOGY & BEHAVIOR

Leptin Reduces Pathology and Improves Memory in a Transgenic Mouse Model of Alzheimer's Disease

(2017) Steven J. Greco et al.   JOURNAL OF ALZHEIMERS DISEASE

Leptin Reduces the Accumulation of Aβ and Phosphorylated Tau Induced by 27-Hydroxycholesterol in Rabbit Organotypic Slices

(2017) Gurdeep Marwarha et al.   JOURNAL OF ALZHEIMERS DISEASE

Long-Term Potentiation: From CaMKII to AMPA Receptor Trafficking

(2016) Bruce E. Herring et al.   Annual Review of Physiology

A Leptin Fragment Mirrors the Cognitive Enhancing and Neuroprotective Actions of Leptin

(2016) Yasaman Malekizadeh et al.   CEREBRAL CORTEX

Role of metabolism in neurodegenerative disorders

(2016) Claudio Procaccini et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Obesity, diabetes, and leptin resistance promote tau pathology in a mouse model of disease

(2016) T.L. Platt et al.   NEUROSCIENCE

Leptin: A Potential Anxiolytic by Facilitation of Fear Extinction

(2015) Wei Wang et al.   CNS Neuroscience & Therapeutics

Leptin attenuates the detrimental effects of β-amyloid on spatial memory and hippocampal later-phase long term potentiation in rats

(2015) Jia-qing Tong et al.   HORMONES AND BEHAVIOR

The role of GluN2A and GluN2B NMDA receptor subunits in AgRP and POMC neurons on body weight and glucose homeostasis

(2015) Aykut Üner et al.   Molecular Metabolism

Alterations in brain leptin signalling in spite of unchanged CSF leptin levels in Alzheimer's disease

(2014) Silvia Maioli et al.   AGING CELL

Leptin gene therapy attenuates neuronal damages evoked by amyloid-β and rescues memory deficits in APP/PS1 mice

(2014) R Pérez-González et al.   GENE THERAPY

20 YEARS OF LEPTIN: Leptin at 20: an overview

(2014) Jeffrey Friedman   JOURNAL OF ENDOCRINOLOGY

20 YEARS OF LEPTIN: Human disorders of leptin action

(2014) I Sadaf Farooqi et al.   JOURNAL OF ENDOCRINOLOGY

Protective Effect of Leptin and Ghrelin against Toxicity Induced by Amyloid-β Oligomers in a Hypothalamic cell Line

(2014) S. Gomes et al.   JOURNAL OF NEUROENDOCRINOLOGY

Neuroprotective effects of leptin in the context of obesity and metabolic disorders

(2014) Cecilia Davis et al.   NEUROBIOLOGY OF DISEASE

Leptin Attenuates Cerebral Ischemia Injury through the Promotion of Energy Metabolism via the PI3K/Akt Pathway

(2013) Jinying Zhang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance

(2013) David J. Bonda et al.   JOURNAL OF NEUROCHEMISTRY

Ghrelin decreases motor deficits after traumatic brain injury

(2013) Nicole E. Lopez et al.   JOURNAL OF SURGICAL RESEARCH

Metabolic abnormalities and hypoleptinemia in α-synuclein A53T mutant mice

(2013) Sarah M. Rothman et al.   NEUROBIOLOGY OF AGING

Leptin and ghrelin prevent hippocampal dysfunction induced by Aβ oligomers

(2013) I. Martins et al.   NEUROSCIENCE

Incorporation of inwardly rectifying AMPA receptors at silent synapses during hippocampal long-term potentiation

(2013) D. Morita et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Leptin regulates amyloid β production via the γ-secretase complex

(2012) Dana M. Niedowicz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Leptin prevents hippocampal synaptic disruption and neuronal cell death induced by amyloid β

(2012) Gayle H. Doherty et al.   NEUROBIOLOGY OF AGING

Bidirectional metabolic regulation of neurocognitive function

(2011) Alexis M. Stranahan et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Interplay between VGLUT Isoforms and Endophilin A1 Regulates Neurotransmitter Release and Short-Term Plasticity

(2011) Matthew C. Weston et al.   NEURON

NMDA receptor subunit composition determines the polarity of leptin-induced synaptic plasticity

(2011) Peter R. Moult et al.   NEUROPHARMACOLOGY

Neurodegeneration in an animal model of Parkinson's disease is exacerbated by a high-fat diet

(2010) Jill K. Morris et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Leptin Regulates AMPA Receptor Trafficking via PTEN Inhibition

(2010) P. R. Moult et al.   JOURNAL OF NEUROSCIENCE

Association of Plasma Leptin Levels With Incident Alzheimer Disease and MRI Measures of Brain Aging

(2009) Wolfgang Lieb   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Body size and risk of MS in two cohorts of US women

(2009) K. L. Munger et al.   NEUROLOGY

Leptin inhibits glycogen synthase kinase-3β to prevent tau phosphorylation in neuronal cells

(2009) Steven J. Greco et al.   NEUROSCIENCE LETTERS

Leptin protects hippocampal CA1 neurons against ischemic injury

(2008) Feng Zhang et al.   JOURNAL OF NEUROCHEMISTRY

Neuroprotective actions of leptin on central and peripheral neurons in vitro

(2008) G.H. Doherty et al.   NEUROSCIENCE

Leptin Replacement Improves Cognitive Development

(2008) Gilberto J. Paz-Filho et al.   PLoS One

Leptin inhibits 4-aminopyridine– and pentylenetetrazole-induced seizures and AMPAR-mediated synaptic transmission in rodents

(2007) Lin Xu et al.   JOURNAL OF CLINICAL INVESTIGATION

Megalin mediates the transport of leptin across the blood-CSF barrier

(2007) Marcelo O. Dietrich et al.   NEUROBIOLOGY OF AGING