Prostaglandin E2 EP1 Receptor Antagonist Improves Motor Deficits and Rescues Memory Decline in R6/1 Mouse Model of Huntington's Disease

Neuronal aggregates are associated with phenotypic onset in the R6/2 Huntington's disease transgenic mouse

(2012) Randi-Michelle Cowin et al.   BEHAVIOURAL BRAIN RESEARCH

Activation of Elk-1 participates as a neuroprotective compensatory mechanism in models of Huntington’s disease

(2012) Marta Anglada-Huguet et al.   JOURNAL OF NEUROCHEMISTRY

Antagonism of Neuronal Prostaglandin E2 Receptor Subtype 1 Mitigates Amyloid β Neurotoxicity In Vitro

(2012) Xianwu Li et al.   Journal of Neuroimmune Pharmacology

Mutant huntingtin, abnormal mitochondrial dynamics, defective axonal transport of mitochondria, and selective synaptic degeneration in Huntington's disease

(2011) P. Hemachandra Reddy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Comparative analysis of pathology and behavioural phenotypes in mouse models of Huntington's disease

(2011) Simon P. Brooks et al.   BRAIN RESEARCH BULLETIN

Long-term memory deficits in Huntington's disease are associated with reduced CBP histone acetylase activity

(2011) A. Giralt et al.   HUMAN MOLECULAR GENETICS

Increased PKA signaling disrupts recognition memory and spatial memory: role in Huntington's disease

(2011) Albert Giralt et al.   HUMAN MOLECULAR GENETICS

Conditional BDNF release under pathological conditions improves Huntington's disease pathology by delaying neuronal dysfunction

(2011) Albert Giralt et al.   Molecular Neurodegeneration

Dantrolene is neuroprotective in Huntington's disease transgenic mouse model

(2011) Xi Chen et al.   Molecular Neurodegeneration

PGE2 EP1 receptor exacerbated neurotoxicity in a mouse model of cerebral ischemia and Alzheimer's disease

(2011) Gehua Zhen et al.   NEUROBIOLOGY OF AGING

Pathophysiology of Huntington's disease: time-dependent alterations in synaptic and receptor function

(2011) L.A. Raymond et al.   NEUROSCIENCE

BDNF regulation under GFAP promoter provides engineered astrocytes as a new approach for long-term protection in Huntington's disease

(2010) A Giralt et al.   GENE THERAPY

Prostaglandin E2-Induced Synaptic Plasticity in Neocortical Networks of Organotypic Slice Cultures

(2010) H. Koch et al.   JOURNAL OF NEUROSCIENCE

Huntington's disease: from molecular pathogenesis to clinical treatment

(2010) Christopher A Ross et al.   LANCET NEUROLOGY

Inhibition of Rho Kinases Enhances the Degradation of Mutant Huntingtin

(2009) Peter O. Bauer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reduced calcineurin protein levels and activity in exon-1 mouse models of Huntington's disease: Role in excitotoxicity

(2009) Xavier Xifró et al.   NEUROBIOLOGY OF DISEASE

Of mice, rats and men: Revisiting the quinolinic acid hypothesis of Huntington's disease

(2009) Robert Schwarcz et al.   PROGRESS IN NEUROBIOLOGY

Emerging roles of PGE2 receptors in models of neurological disease

(2009) Katrin Andreasson   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Cyclooxygenase-2 inhibition improves amyloid-β-mediated suppression of memory and synaptic plasticity

(2008) Linda A. Kotilinek et al.   BRAIN

Calcium ions in neuronal degeneration

(2008) Urszula Wojda et al.   IUBMB LIFE

Altered hippocampal long-term synaptic plasticity in mice deficient in the PGE2 EP2 receptor

(2008) Hongwei Yang et al.   JOURNAL OF NEUROCHEMISTRY

Dopaminergic and Glutamatergic Signaling Crosstalk in Huntington's Disease Neurodegeneration: The Role of p25/Cyclin-Dependent Kinase 5

(2008) P. Paoletti et al.   JOURNAL OF NEUROSCIENCE

Brain-derived neurotrophic factor modulates the severity of cognitive alterations induced by mutant huntingtin: Involvement of phospholipaseCγ activity and glutamate receptor expression

(2008) A. Giralt et al.   NEUROSCIENCE

Gene–environment interactions modulating cognitive function and molecular correlates of synaptic plasticity in Huntington’s disease transgenic mice

(2007) Jess Nithianantharajah et al.   NEUROBIOLOGY OF DISEASE

Disruption of striatal glutamatergic transmission induced by mutant huntingtin involves remodeling of both postsynaptic density and NMDA receptor signaling

(2007) Jesús F. Torres-Peraza et al.   NEUROBIOLOGY OF DISEASE