Inflammation and Fibrogenesis in MAFLD: Role of the Hepatic Immune System
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Title
Inflammation and Fibrogenesis in MAFLD: Role of the Hepatic Immune System
Authors
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Journal
Frontiers in Medicine
Volume 8, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-12-09
DOI
10.3389/fmed.2021.781567
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Note: Only part of the references are listed.- Immunity as Cornerstone of Non-Alcoholic Fatty Liver Disease: The Contribution of Oxidative Stress in the Disease Progression
- (2021) Marcello Dallio et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- How does hepatic lipid accumulation lead to lipotoxicity in non-alcoholic fatty liver disease?
- (2021) Yana Geng et al. Hepatology International
- Therapeutic pipeline in nonalcoholic steatohepatitis
- (2021) Raj Vuppalanchi et al. Nature Reviews Gastroenterology & Hepatology
- Revisiting the Role of Natural Killer Cells in Non-Alcoholic Fatty Liver Disease
- (2021) María Luz Martínez-Chantar et al. Frontiers in Immunology
- The Roles of Neutrophils in the Pathogenesis of Liver Diseases
- (2021) Jiaojiao Tang et al. Frontiers in Immunology
- Inflammatory Mechanisms Underlying Nonalcoholic Steatohepatitis and the Transition to Hepatocellular Carcinoma
- (2021) Moritz Peiseler et al. Cancers
- Oxidative Stress in Non-alcoholic Fatty Liver Disease. An Updated Mini Review
- (2021) Anna Pia Delli Bovi et al. Frontiers in Medicine
- The Role of Fructose in Non-Alcoholic Steatohepatitis: Old Relationship and New Insights
- (2021) Alessandro Federico et al. Nutrients
- New drugs for NASH
- (2021) Somaya A. M. Albhaisi et al. LIVER INTERNATIONAL
- Mechanisms of Fibrosis Development in NASH
- (2020) Robert F. Schwabe et al. GASTROENTEROLOGY
- MAFLD: A consensus-driven proposed nomenclature for metabolic associated fatty liver disease
- (2020) Mohammed Eslam et al. GASTROENTEROLOGY
- Cenicriviroc Treatment for Adults with Nonalcoholic Steatohepatitis and Fibrosis: Final Analysis of the Phase 2b CENTAUR Study
- (2020) Vlad Ratziu et al. HEPATOLOGY
- Inflammation and fibrosis in chronic liver diseases including non-alcoholic fatty liver disease and hepatitis C
- (2020) Sudeep Tanwar et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Role of oxidative stress in the pathogenesis of nonalcoholic fatty liver disease
- (2020) Ze Chen et al. FREE RADICAL BIOLOGY AND MEDICINE
- Characterization of the immune cell landscape of patients with NAFLD
- (2020) Tom Diedrich et al. PLoS One
- The Medium-Chain Fatty Acid Receptor GPR84 Mediates Myeloid Cell Infiltration Promoting Steatohepatitis and Fibrosis
- (2020) Tobias Puengel et al. Journal of Clinical Medicine
- The cellular pathways of liver fibrosis in non-alcoholic steatohepatitis
- (2020) Nahum Méndez-Sánchez et al. Annals of Translational Medicine
- Liver fibrogenesis: un update on established and emerging basic concepts
- (2020) Erica Novo et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Bariatric Surgery Provides Long-term Resolution of Nonalcoholic Steatohepatitis and Regression of Fibrosis
- (2020) Guillaume Lassailly et al. GASTROENTEROLOGY
- From NAFLD to MAFLD: Implications of a premature change in terminology
- (2020) Zobair M Younossi et al. HEPATOLOGY
- NAFLD as a continuum: from obesity to metabolic syndrome and diabetes
- (2020) Amélio F. Godoy-Matos et al. Diabetology & Metabolic Syndrome
- Lipophagy Impairment Is Associated With Disease Progression in NAFLD
- (2020) Simone Carotti et al. Frontiers in Physiology
- Roles of Hepatic Innate and Innate-Like Lymphocytes in Nonalcoholic Steatohepatitis
- (2020) Yongyan Chen et al. Frontiers in Immunology
- Role of Extracellular Vesicles in the Pathophysiology, Diagnosis and Tracking of Non-Alcoholic Fatty Liver Disease
- (2020) Lauren A. Newman et al. Journal of Clinical Medicine
- Reregulation of hepatic stellate cell contraction and cirrhotic portal hypertension by Wnt/β‐catenin signaling via interaction with Gli1
- (2020) Feng Zhang et al. BRITISH JOURNAL OF PHARMACOLOGY
- The Asian Pacific Association for the Study of the Liver clinical practice guidelines for the diagnosis and management of metabolic associated fatty liver disease
- (2020) Mohammed Eslam et al. Hepatology International
- Understanding lipotoxicity in NAFLD pathogenesis: is CD36 a key driver?
- (2020) Patricia Rada et al. Cell Death & Disease
- Immunological mechanisms and therapeutic targets of fatty liver diseases
- (2020) Hua Wang et al. Cellular & Molecular Immunology
- Chronic Inflammation in Non-Alcoholic Steatohepatitis: Molecular Mechanisms and Therapeutic Strategies
- (2020) Carmelo Luci et al. Frontiers in Endocrinology
- Genetic and epigenetic factors determining NAFLD risk
- (2020) Wenke Jonas et al. Molecular Metabolism
- The Role of Innate Immune Cells in Nonalcoholic Steatohepatitis
- (2019) Jingjing Cai et al. HEPATOLOGY
- Activated NK cells kill hepatic stellate cells via p38/PI3K signaling in a TRAIL‐involved degranulation manner
- (2019) Tianyang Li et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Neutrophil-to-lymphocyte ratio is independently associated with inflammatory activity and fibrosis grade in nonalcoholic fatty liver disease
- (2019) Tawfik Khoury et al. EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
- Myeloid cells in liver and bone marrow acquire a functionally distinct inflammatory phenotype during obesity-related steatohepatitis
- (2019) Oliver Krenkel et al. GUT
- Increased proteinase 3 and neutrophil elastase plasma concentrations are associated with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes
- (2019) Andreea-Manuela Mirea et al. MOLECULAR MEDICINE
- ECM1 Prevents Activation of Transforming Growth Factor beta, Hepatic Stellate Cells, and Fibrogenesis in Mice
- (2019) Weiguo Fan et al. GASTROENTEROLOGY
- The cell biology of the hepatocyte: A membrane trafficking machine
- (2019) Ryan J. Schulze et al. JOURNAL OF CELL BIOLOGY
- γδ T cells Promote Steatohepatitis by Orchestrating Innate and Adaptive Immune Programming
- (2019) Alejandro Torres‐Hernandez et al. HEPATOLOGY
- The biology and functional importance of MAIT cells
- (2019) Dale I. Godfrey et al. NATURE IMMUNOLOGY
- A role for IL-1 inhibitors in the treatment of non-alcoholic fatty liver disease (NAFLD)?
- (2019) Herbert Tilg et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Adaptive immunity: an emerging player in the progression of NAFLD
- (2019) Salvatore Sutti et al. Nature Reviews Gastroenterology & Hepatology
- Liver-Mediated Adaptive Immune Tolerance
- (2019) Meijuan Zheng et al. Frontiers in Immunology
- Cenicriviroc for the treatment of liver fibrosis in adults with nonalcoholic steatohepatitis: AURORA Phase 3 study design
- (2019) Quentin M. Anstee et al. Contemporary Clinical Trials
- Extracellular vesicles: exosomes, microparticles, their parts, and their targets to enable their biomanufacturing and clinical applications
- (2019) Chen-Yuan Kao et al. CURRENT OPINION IN BIOTECHNOLOGY
- Effects of Belapectin, an Inhibitor of Galectin-3, in Patients With Nonalcoholic Steatohepatitis With Cirrhosis and Portal Hypertension
- (2019) Naga Chalasani et al. GASTROENTEROLOGY
- Immune Responses in the Liver
- (2018) Paul Kubes et al. Annual Review of Immunology
- Immunotherapy with oral administration of humanized anti-CD3 monoclonal antibody: A novel gut-immune system-based therapy for metaflammation and NASH
- (2018) Yaron Ilan et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Serum Activity of Macrophage-Derived Adenosine Deaminase 2 Is Associated With Liver Fibrosis in Nonalcoholic Fatty Liver Disease
- (2018) Z. Gordon Jiang et al. Clinical Gastroenterology and Hepatology
- Cenicriviroc for the treatment of non-alcoholic steatohepatitis and liver fibrosis
- (2018) Frank Tacke EXPERT OPINION ON INVESTIGATIONAL DRUGS
- B2-Lymphocyte responses to oxidative stress-derived antigens contribute to the evolution of nonalcoholic fatty liver disease (NAFLD)
- (2018) Stefania Bruzzì et al. FREE RADICAL BIOLOGY AND MEDICINE
- Neutrophil extracellular traps promote inflammation and development of hepatocellular carcinoma in nonalcoholic steatohepatitis
- (2018) Dirk J. van der Windt et al. HEPATOLOGY
- A randomized, placebo-controlled trial of cenicriviroc for treatment of nonalcoholic steatohepatitis with fibrosis
- (2018) Scott L. Friedman et al. HEPATOLOGY
- Nonalcoholic fatty liver disease incidence and impact on metabolic burden and death: A 20 year-community study
- (2018) Alina M. Allen et al. HEPATOLOGY
- Galectin-3: One Molecule for an Alphabet of Diseases, from A to Z
- (2018) Salvatore Sciacchitano et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- A multi-strain probiotic reduces the fatty liver index, cytokines and aminotransferase levels in NAFLD patients: evidence from a randomized clinical trial
- (2018) Journal of Gastrointestinal and Liver Diseases
- JKB-121 in patients with nonalcoholic steatohepatitis: A phase 2 double blind randomized placebo control study
- (2018) A.M. Diehl et al. JOURNAL OF HEPATOLOGY
- Determinants of fibrosis progression and regression in NASH
- (2018) Detlef Schuppan et al. JOURNAL OF HEPATOLOGY
- Genetics and epigenetics of NAFLD and NASH: Clinical impact
- (2018) Mohammed Eslam et al. JOURNAL OF HEPATOLOGY
- Danger-Associated Molecular Patterns Derived From the Extracellular Matrix Provide Temporal Control of Innate Immunity
- (2018) Charles W. Frevert et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- Matrix metalloproteinases and liver fibrosis (translational aspects)
- (2018) Elke Roeb MATRIX BIOLOGY
- Mechanisms of NAFLD development and therapeutic strategies
- (2018) Scott L. Friedman et al. NATURE MEDICINE
- Liver sinusoidal endothelial cells — gatekeepers of hepatic immunity
- (2018) Shishir Shetty et al. Nature Reviews Gastroenterology & Hepatology
- Role of Oxidative Stress in Pathophysiology of Nonalcoholic Fatty Liver Disease
- (2018) Mario Masarone et al. Oxidative Medicine and Cellular Longevity
- Mucosal-associated invariant T cells are a profibrogenic immune cell population in the liver
- (2018) Pushpa Hegde et al. Nature Communications
- Integrated analysis of hepatic mRNA and miRNA profiles identified molecular networks and potential biomarkers of NAFLD
- (2018) Mingzhe Zhu et al. Scientific Reports
- NKG2D and Its Ligands: “One for All, All for One”
- (2018) Alessandra Zingoni et al. Frontiers in Immunology
- Innate Immune Signaling in Nonalcoholic Fatty Liver Disease and Cardiovascular Diseases
- (2018) Jingjing Cai et al. Annual Review of Pathology-Mechanisms of Disease
- Type 3 cytokines in liver fibrosis and liver cancer
- (2018) Manuel Flores Molina et al. CYTOKINE
- Macrophage Markers are Poorly Associated with Liver Histology in Children with Non-Alcoholic Fatty Liver Disease
- (2018) Konstantin Kazankov et al. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
- Liver fibrosis: Pathophysiology, pathogenetic targets and clinical issues
- (2018) Maurizio Parola et al. MOLECULAR ASPECTS OF MEDICINE
- Bile Acids Activated Receptors Regulate Innate Immunity
- (2018) Stefano Fiorucci et al. Frontiers in Immunology
- Mucosal-Associated Invariant T Cells Improve Nonalcoholic Fatty Liver Disease Through Regulating Macrophage Polarization
- (2018) Yanmei Li et al. Frontiers in Immunology
- Differential Activation of Hepatic Invariant NKT Cell Subsets Plays a Key Role in Progression of Nonalcoholic Steatohepatitis
- (2018) Igor Maricic et al. JOURNAL OF IMMUNOLOGY
- Metabolism as a guiding force for immunity
- (2018) Jonathan Jung et al. NATURE CELL BIOLOGY
- The role of macrophages in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis
- (2018) Konstantin Kazankov et al. Nature Reviews Gastroenterology & Hepatology
- Hepatocyte Notch activation induces liver fibrosis in nonalcoholic steatohepatitis
- (2018) Changyu Zhu et al. Science Translational Medicine
- Single cell RNA sequencing of human liver reveals distinct intrahepatic macrophage populations
- (2018) Sonya A. MacParland et al. Nature Communications
- Effect of GPR84 deletion on obesity and diabetes development in mice fed long chain or medium chain fatty acid rich diets
- (2017) Eugene Du Toit et al. EUROPEAN JOURNAL OF NUTRITION
- Estrogen Signals Through Peroxisome Proliferator-Activated Receptor−γ Coactivator 1α to Reduce Oxidative Damage Associated With Diet-Induced Fatty Liver Disease
- (2017) Aurèle Besse-Patin et al. GASTROENTEROLOGY
- The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases
- (2017) Naga Chalasani et al. HEPATOLOGY
- Adipokines and Non-Alcoholic Fatty Liver Disease: Multiple Interactions
- (2017) et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The differential organogenesis and functionality of two liver-draining lymph nodes in mice
- (2017) Jiali Yu et al. JOURNAL OF AUTOIMMUNITY
- Targeting hepatic macrophages to treat liver diseases
- (2017) Frank Tacke JOURNAL OF HEPATOLOGY
- Bi-directional analysis between fatty liver and cardiovascular disease risk factors
- (2017) Jiantao Ma et al. JOURNAL OF HEPATOLOGY
- Cholesterol crystallization within hepatocyte lipid droplets and its role in murine NASH
- (2017) George N. Ioannou et al. JOURNAL OF LIPID RESEARCH
- Inflammation, metaflammation and immunometabolic disorders
- (2017) Gökhan S. Hotamisligil NATURE
- Mechanisms of hepatic stellate cell activation
- (2017) Takuma Tsuchida et al. Nature Reviews Gastroenterology & Hepatology
- The microbiota maintain homeostasis of liver-resident γδT-17 cells in a lipid antigen/CD1d-dependent manner
- (2017) Fenglei Li et al. Nature Communications
- Antibody-Directed Glucocorticoid Targeting to CD163 in M2-type Macrophages Attenuates Fructose-Induced Liver Inflammatory Changes
- (2017) Pia Svendsen et al. Molecular Therapy-Methods & Clinical Development
- Randomised clinical study: GR-MD-02, a galectin-3 inhibitor, vs. placebo in patients having non-alcoholic steatohepatitis with advanced fibrosis
- (2016) S. A. Harrison et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Lipotoxicity in steatohepatitis occurs despite an increase in tricarboxylic acid cycle activity
- (2016) Rainey E. Patterson et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Modulation of liver tolerance by conventional and nonconventional antigen-presenting cells and regulatory immune cells
- (2016) Andrea Kristina Horst et al. Cellular & Molecular Immunology
- Hepatic macrophages in homeostasis and liver diseases: from pathogenesis to novel therapeutic strategies
- (2016) Cynthia Ju et al. Cellular & Molecular Immunology
- Innate Immunity and Inflammation in NAFLD/NASH
- (2016) Marco Arrese et al. DIGESTIVE DISEASES AND SCIENCES
- Lipid-Induced Signaling Causes Release of Inflammatory Extracellular Vesicles From Hepatocytes
- (2016) Petra Hirsova et al. GASTROENTEROLOGY
- Combination of Mass Cytometry and Imaging Analysis Reveals Origin, Location, and Functional Repopulation of Liver Myeloid Cells in Mice
- (2016) Bruna Araujo David et al. GASTROENTEROLOGY
- The MBOAT7-TMC4 Variant rs641738 Increases Risk of Nonalcoholic Fatty Liver Disease in Individuals of European Descent
- (2016) Rosellina Margherita Mancina et al. GASTROENTEROLOGY
- Correction: Mixed lineage kinase 3 mediates release of C-X-C motif ligand 10-bearing chemotactic extracellular vesicles from lipotoxic hepatocytes
- (2016) HEPATOLOGY
- Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes
- (2016) Zobair M. Younossi et al. HEPATOLOGY
- The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota
- (2016) Jérôme Boursier et al. HEPATOLOGY
- Role of thrombospondin 1 in liver diseases
- (2016) Yanzhang Li et al. HEPATOLOGY RESEARCH
- Unsupervised High-Dimensional Analysis Aligns Dendritic Cells across Tissues and Species
- (2016) Martin Guilliams et al. IMMUNITY
- Toll-like Receptor 4 on Macrophage Promotes the Development of Steatohepatitis-related Hepatocellular Carcinoma in Mice
- (2016) Kouichi Miura et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- EASL–EASD–EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease
- (2016) JOURNAL OF HEPATOLOGY
- The macrophage activation marker sCD163 is associated with morphological disease stages in patients with non-alcoholic fatty liver disease
- (2016) Konstantin Kazankov et al. LIVER INTERNATIONAL
- The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)
- (2016) Elena Buzzetti et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Immunology in the liver — from homeostasis to disease
- (2016) Felix Heymann et al. Nature Reviews Gastroenterology & Hepatology
- The role of immune cells in metabolism-related liver inflammation and development of non-alcoholic steatohepatitis (NASH)
- (2016) Marina Nati et al. REVIEWS IN ENDOCRINE & METABOLIC DISORDERS
- Trained immunity: A program of innate immune memory in health and disease
- (2016) M. G. Netea et al. SCIENCE
- Immune Imbalances in Non-Alcoholic Fatty Liver Disease: From General Biomarkers and Neutrophils to Interleukin-17 Axis Activation and New Therapeutic Targets
- (2016) Feliciano Chanana Paquissi Frontiers in Immunology
- Toll-like receptor 7 affects the pathogenesis of non-alcoholic fatty liver disease
- (2016) Sokho Kim et al. Scientific Reports
- Circulating periostin in relation to insulin resistance and nonalcoholic fatty liver disease among overweight and obese subjects
- (2016) Zhen Yang et al. Scientific Reports
- Novel insights into the function and dynamics of extracellular matrix in liver fibrosis
- (2015) Morten A. Karsdal et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Fluorescent cell-traceable dexamethasone-loaded liposomes for the treatment of inflammatory liver diseases
- (2015) Matthias Bartneck et al. BIOMATERIALS
- Hepatocytes: a key cell type for innate immunity
- (2015) Zhou Zhou et al. Cellular & Molecular Immunology
- The balance between IL-17 and IL-22 produced by liver-infiltrating T-helper cells critically controls NASH development in mice
- (2015) S. Rolla et al. CLINICAL SCIENCE
- Phenotypic and functional characterization of macrophages with therapeutic potential generated from human cirrhotic monocytes in a cohort study
- (2015) Joanna K. Moore et al. CYTOTHERAPY
- Liver fibrosis occurs through dysregulation of MyD88-dependent innate B-cell activity
- (2015) Manoj Thapa et al. HEPATOLOGY
- CX3CR1 is a gatekeeper for intestinal barrier integrity in mice: Limiting steatohepatitis by maintaining intestinal homeostasis
- (2015) Kai Markus Schneider et al. HEPATOLOGY
- Oral Administration of OKT3 MAb to Patients with NASH, Promotes Regulatory T-cell Induction, and Alleviates Insulin Resistance: Results of a Phase IIa Blinded Placebo-Controlled Trial
- (2015) Gadi Lalazar et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Small intestinal bacterial overgrowth and toll-like receptor signaling in patients with non-alcoholic fatty liver disease
- (2015) Shweta Kapil et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- The Hippo pathway effector YAP controls mouse hepatic stellate cell activation
- (2015) Inge Mannaerts et al. JOURNAL OF HEPATOLOGY
- Progression from Nonalcoholic Fatty Liver to Nonalcoholic Steatohepatitis Is Marked by a Higher Frequency of Th17 Cells in the Liver and an Increased Th17/Resting Regulatory T Cell Ratio in Peripheral Blood and in the Liver
- (2015) Monika Rau et al. JOURNAL OF IMMUNOLOGY
- Adipocytokines and hepatic fibrosis
- (2015) Neeraj K. Saxena et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- The Role of Dendritic Cells in Fibrosis Progression in Nonalcoholic Fatty Liver Disease
- (2015) Paloma Almeda-Valdes et al. Biomed Research International
- Synbiotic supplementation in nonalcoholic fatty liver disease: a randomized, double-blind, placebo-controlled pilot study
- (2014) Tannaz Eslamparast et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver
- (2014) Alexandra Naba et al. BMC CANCER
- Metabolic Activation of Intrahepatic CD8+ T Cells and NKT Cells Causes Nonalcoholic Steatohepatitis and Liver Cancer via Cross-Talk with Hepatocytes
- (2014) Monika Julia Wolf et al. CANCER CELL
- Roles for Chemokines in Liver Disease
- (2014) Fabio Marra et al. GASTROENTEROLOGY
- Circulating microRNA signature in non-alcoholic fatty liver disease: from serum non-coding RNAs to liver histology and disease pathogenesis
- (2014) Carlos J Pirola et al. GUT
- Periostin promotes liver steatosis and hypertriglyceridemia through downregulation of PPARα
- (2014) Yan Lu et al. JOURNAL OF CLINICAL INVESTIGATION
- Vascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis
- (2014) Chris J. Weston et al. JOURNAL OF CLINICAL INVESTIGATION
- The role of Kupffer cells in hepatitis B and hepatitis C virus infections
- (2014) Arjan Boltjes et al. JOURNAL OF HEPATOLOGY
- TGF-β-dependent induction of CD4+CD25+Foxp3+ Tregs by liver sinusoidal endothelial cells
- (2014) Antonella Carambia et al. JOURNAL OF HEPATOLOGY
- Serum immunoglobulin levels predict fibrosis in patients with non-alcoholic fatty liver disease
- (2014) Stuart McPherson et al. JOURNAL OF HEPATOLOGY
- Macrophage heterogeneity in liver injury and fibrosis
- (2014) Frank Tacke et al. JOURNAL OF HEPATOLOGY
- Mice Lacking Natural Killer T Cells Are More Susceptible to Metabolic Alterations following High Fat Diet Feeding
- (2014) Brittany V. Martin-Murphy et al. PLoS One
- Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity
- (2014) S. Saeed et al. SCIENCE
- Role of gut microbiota and Toll-like receptors in nonalcoholic fatty liver disease
- (2014) Kouichi Miura WORLD JOURNAL OF GASTROENTEROLOGY
- IFN-γ deficiency attenuates hepatic inflammation and fibrosis in a steatohepatitis model induced by a methionine- and choline-deficient high-fat diet
- (2013) Xiao-Yu Luo et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- A systematic review: Burden and severity of subclinical cardiovascular disease among those with nonalcoholic fatty liver; Should we care?
- (2013) Ebenezer T. Oni et al. ATHEROSCLEROSIS
- The liver works as a school to educate regulatory immune cells
- (2013) Fenglei Li et al. Cellular & Molecular Immunology
- Relationship Between Methylome and Transcriptome in Patients With Nonalcoholic Fatty Liver Disease
- (2013) Susan K. Murphy et al. GASTROENTEROLOGY
- Dendritic cells limit fibroinflammatory injury in nonalcoholic steatohepatitis in mice
- (2013) Justin R. Henning et al. HEPATOLOGY
- M2 Kupffer cells promote M1 Kupffer cell apoptosis: A protective mechanism against alcoholic and nonalcoholic fatty liver disease
- (2013) Jinghong Wan et al. HEPATOLOGY
- Cannabinoid receptor 2 counteracts interleukin-17-induced immune and fibrogenic responses in mouse liver
- (2013) Adrien Guillot et al. HEPATOLOGY
- Free cholesterol accumulation in hepatic stellate cells: Mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice
- (2013) Kengo Tomita et al. HEPATOLOGY
- Adaptive immune responses triggered by oxidative stress contribute to hepatic inflammation in NASH
- (2013) Salvatore Sutti et al. HEPATOLOGY
- IL-17 signaling accelerates the progression of nonalcoholic fatty liver disease in mice
- (2013) Isaac T.W. Harley et al. HEPATOLOGY
- The portal inflammatory infiltrate and ductular reaction in human nonalcoholic fatty liver disease
- (2013) Victoria L. Gadd et al. HEPATOLOGY
- Dendritic cells in liver injury and fibrosis: Shortcomings and promises
- (2013) Veronika Lukacs-Kornek et al. JOURNAL OF HEPATOLOGY
- Food-derived peroxidized fatty acids may trigger hepatic inflammation: A novel hypothesis to explain steatohepatitis
- (2013) Therese Böhm et al. JOURNAL OF HEPATOLOGY
- IL-17A Plays a Critical Role in the Pathogenesis of Liver Fibrosis through Hepatic Stellate Cell Activation
- (2013) Z. Tan et al. JOURNAL OF IMMUNOLOGY
- Therapy of Experimental NASH and Fibrosis with Galectin Inhibitors
- (2013) Peter G. Traber et al. PLoS One
- Effect of exercise training on metabolic flexibility in response to a high-fat diet in obese individuals
- (2012) Gina M. Battaglia et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Promotion of Hepatocellular Carcinoma by the Intestinal Microbiota and TLR4
- (2012) Dianne H. Dapito et al. CANCER CELL
- Dendritic Cell Populations With Different Concentrations of Lipid Regulate Tolerance and Immunity in Mouse and Human Liver
- (2012) Junaid Ibrahim et al. GASTROENTEROLOGY
- Interleukin-17 Signaling in Inflammatory, Kupffer Cells, and Hepatic Stellate Cells Exacerbates Liver Fibrosis in Mice
- (2012) Fanli Meng et al. GASTROENTEROLOGY
- NKT-associated hedgehog and osteopontin drive fibrogenesis in non-alcoholic fatty liver disease
- (2012) Wing-Kin Syn et al. GUT
- B cell-activating factor is associated with the histological severity of nonalcoholic fatty liver disease
- (2012) Teruki Miyake et al. Hepatology International
- Toxic lipids stored by Kupffer cells correlates with their pro-inflammatory phenotype at an early stage of steatohepatitis
- (2012) Anne Leroux et al. JOURNAL OF HEPATOLOGY
- CCN1 expression in hepatocytes contributes to macrophage infiltration in nonalcoholic fatty liver disease in mice
- (2012) Zhaolian Bian et al. JOURNAL OF LIPID RESEARCH
- Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
- (2012) Jorge Henao-Mejia et al. NATURE
- Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase
- (2012) Saswata Talukdar et al. NATURE MEDICINE
- The role of Kupffer cells in the morphogenesis of nonalcoholic steatohepatitis – ultrastructural findings. The first report in pediatric patients
- (2012) Joanna Maria Lotowska et al. SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
- Mechanisms of hepatic fibrogenesis
- (2011) Ursula E. Lee et al. BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY
- NKp46-mediated killing of human and mouse hepatic stellate cells attenuates liver fibrosis
- (2011) Chamutal Gur et al. GUT
- Pharmacological inhibition of the chemokine CCL2 (MCP-1) diminishes liver macrophage infiltration and steatohepatitis in chronic hepatic injury
- (2011) Christer Baeck et al. GUT
- Murine hepatic stellate cells veto CD8 T cell activation by a CD54-dependent mechanism
- (2011) Frank A. Schildberg et al. HEPATOLOGY
- Macrophage therapy for murine liver fibrosis recruits host effector cells improving fibrosis, regeneration, and function
- (2011) James A. Thomas et al. HEPATOLOGY
- Osteopontin, an oxidant stress sensitive cytokine, up-regulates collagen-I via integrin αVβ3 engagement and PI3K/pAkt/NFκB signaling
- (2011) Raquel Urtasun et al. HEPATOLOGY
- Altered Phenotype and Functionality of Circulating Immune Cells Characterize Adult Patients with Nonalcoholic Steatohepatitis
- (2011) María Eugenia Inzaugarat et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Lack of interleukin-1α or interleukin-1β inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice
- (2011) Yehuda Kamari et al. JOURNAL OF HEPATOLOGY
- Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets
- (2011) R. D. Michalek et al. JOURNAL OF IMMUNOLOGY
- Increased production of sonic hedgehog by ballooned hepatocytes
- (2011) Fatima Rangwala et al. JOURNAL OF PATHOLOGY
- Innate or Adaptive Immunity? The Example of Natural Killer Cells
- (2011) E. Vivier et al. SCIENCE
- Macrophage Diversity Enhances Tumor Progression and Metastasis
- (2010) Bin-Zhi Qian et al. CELL
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- (2010) R. Scott Rector et al. JOURNAL OF HEPATOLOGY
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- (2010) Y. Ilan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2009) Michael Charlton et al. HEPATOLOGY
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- (2009) Linde Meyaard IMMUNOLOGY LETTERS
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- (2009) A. Mencarelli et al. JOURNAL OF IMMUNOLOGY
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- (2009) Paul L. Bollyky et al. JOURNAL OF LEUKOCYTE BIOLOGY
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- (2009) Naim Alkhouri et al. Expert Review of Gastroenterology & Hepatology
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- (2008) Frank A. Schildberg et al. EUROPEAN JOURNAL OF IMMUNOLOGY
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- (2008) A. Karlsson et al. GLYCOBIOLOGY
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- (2008) Hirotaka Kazama et al. IMMUNITY
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- (2008) Michael Kremer et al. WORLD JOURNAL OF GASTROENTEROLOGY
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