Activated NK cells kill hepatic stellate cells via p38/PI3K signaling in a TRAIL‐involved degranulation manner

Incidence of Hepatocellular Carcinoma in All 50 United States, From 2000 Through 2012

(2017) Donna L. White et al.   GASTROENTEROLOGY

Heat shock protein 27 downstream of P38-PI3K/Akt signaling antagonizes melatonin-induced apoptosis of SGC-7901 gastric cancer cells

(2016) Wenjie Deng et al.   Cancer Cell International

NKp46+ natural killer cells attenuate metabolism-induced hepatic fibrosis by regulating macrophage activation in mice

(2016) Annie-Carole Tosello-Trampont et al.   HEPATOLOGY

HIV-1 Tat Protein Activates both the MyD88 and TRIF Pathways To Induce Tumor Necrosis Factor Alpha and Interleukin-10 in Human Monocytes

(2016) Rémi Planès et al.   JOURNAL OF VIROLOGY

Natural Killer Cells and Liver Fibrosis

(2016) Frank Fasbender et al.   Frontiers in Immunology

HCV core protein inhibits polarization and activity of both M1 and M2 macrophages through the TLR2 signaling pathway

(2016) Qianqian Zhang et al.   Scientific Reports

Liver natural killer cells: subsets and roles in liver immunity

(2015) Hui Peng et al.   Cellular & Molecular Immunology

Favorable in vitro effects of combined IL-12 and IL-18 treatment on NK cell cytotoxicity and CD25 receptor expression in metastatic melanoma patients

(2015) Katarina Mirjačić Martinović et al.   Journal of Translational Medicine

Toll-like receptor 3 regulates NK cell responses to cytokines and controls experimental metastasis

(2015) Camille Guillerey et al.   OncoImmunology

IL-30 (IL27p28) attenuates liver fibrosis through inducing NKG2D-rae1 interaction between NKT and activated hepatic stellate cells in mice

(2014) Abhisek Mitra et al.   HEPATOLOGY

TRAIL-producing NK cells contribute to liver injury and related fibrogenesis in the context of GNMT deficiency

(2014) Sara Fernández-Álvarez et al.   LABORATORY INVESTIGATION

NK cell development and function – Plasticity and redundancy unleashed

(2014) Frank Cichocki et al.   SEMINARS IN IMMUNOLOGY

The synergy in cytokine production through MyD88-TRIF pathways is co-ordinated with ERK phosphorylation in macrophages

(2013) Rebecca Suet Ting Tan et al.   IMMUNOLOGY AND CELL BIOLOGY

Membrane-bound TRAIL Supplements Natural Killer Cell Cytotoxicity Against Neuroblastoma Cells

(2013) Michael A. Sheard et al.   JOURNAL OF IMMUNOTHERAPY

Natural killer and natural killer T cells in liver fibrosis

(2012) Bin Gao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

NK cells from HCV-infected patients effectively induce apoptosis of activated primary human hepatic stellate cells in a TRAIL-, FasL- and NKG2D-dependent manner

(2012) Andreas Glässner et al.   LABORATORY INVESTIGATION

Synergy between TLR3 and IL-18 promotes IFN-γ dependent TRAIL expression in human liver NK cells

(2011) Zhengkun Tu et al.   CELLULAR IMMUNOLOGY

Frequency and Outcomes of Liver Transplantation for Nonalcoholic Steatohepatitis in the United States

(2011) Michael R. Charlton et al.   GASTROENTEROLOGY

Suppression of innate immunity (natural killer cell/interferon-γ) in the advanced stages of liver fibrosis in mice

(2011) Won-Il Jeong et al.   HEPATOLOGY

ESAT-6 induced COX-2 expression involves coordinated interplay between PI3K and MAPK signaling

(2011) Senthil Kumar A et al.   MOLECULAR IMMUNOLOGY

Protective role of PI3-kinase/Akt/eNOS signaling in mechanical stress through inhibition of p38 mitogen-activated protein kinase in mouse lung

(2010) Xin-qi Peng et al.   ACTA PHARMACOLOGICA SINICA

Amelioration of hepatic fibrosis by NK cell activation

(2010) N. Muhanna et al.   GUT

Lipid Raft Assembly and Lck Recruitment in TRAIL Costimulation Mediates NF- B Activation and T Cell Proliferation

(2010) S.-C. Huang et al.   JOURNAL OF IMMUNOLOGY

Escape of HIV-1-Infected Dendritic Cells from TRAIL-Mediated NK Cell Cytotoxicity during NK-DC Cross-Talk—A Pivotal Role of HMGB1

(2010) Marie-Thérèse Melki et al.   PLoS Pathogens

Synergy of TRIF-dependent TLR3 and MyD88-dependent TLR7 in up-regulating expression of mouse FPR2, a promiscuous G-protein-coupled receptor, in microglial cells

(2009) Keqiang Chen et al.   JOURNAL OF NEUROIMMUNOLOGY

Mononuclear cells in liver fibrosis

(2009) Fabio Marra et al.   Seminars in Immunopathology

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY

TLR-dependent cross talk between human Kupffer cells and NK cells

(2008) Zhengkun Tu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Functions of natural killer cells

(2008) Eric Vivier et al.   NATURE IMMUNOLOGY