Immunity as Cornerstone of Non-Alcoholic Fatty Liver Disease: The Contribution of Oxidative Stress in the Disease Progression

MAFLD: A consensus-driven proposed nomenclature for metabolic associated fatty liver disease

(2020) Mohammed Eslam et al.   GASTROENTEROLOGY

IRG1/Itaconate Activates Nrf2 in Hepatocytes to Protect Against Liver Ischemia–Reperfusion Injury

(2020) Zhongjie Yi et al.   HEPATOLOGY

Liver macrophages inhibit the endogenous antioxidant response in obesity-associated insulin resistance

(2020) Valerio Azzimato et al.   Science Translational Medicine

Dimethyl fumarate ameliorates hepatic inflammation in alcohol related liver disease

(2020) Moris Sangineto et al.   LIVER INTERNATIONAL

Lipid Metabolism in Development and Progression of Hepatocellular Carcinoma

(2020) Moris Sangineto et al.   Cancers

Hepatic Stellate Cells and Hepatocarcinogenesis

(2020) Anna E. Barry et al.   Frontiers in Cell and Developmental Biology

Evaluation and Management of Extrahepatic Manifestations of Nonalcoholic Fatty Liver Disease

(2020) Karn Wijarnpreecha et al.   Clinical and Molecular Hepatology

Implication of oxidative stress in the pathogenesis of systemic sclerosis via inflammation, autoimmunity and fibrosis

(2019) Ludivine Doridot et al.   Redox Biology

Resilient hepatic mitochondrial function and lack of iNOS dependence in diet-induced insulin resistance

(2019) Pamela A. Kakimoto et al.   PLoS One

Mitochondrial fission-induced mtDNA stress promotes tumor-associated macrophage infiltration and HCC progression

(2019) Dengke Bao et al.   ONCOGENE

Innate immune regulatory networks in hepatic lipid metabolism

(2019) Lan Bai et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Activated NK cells kill hepatic stellate cells via p38/PI3K signaling in a TRAIL‐involved degranulation manner

(2019) Tianyang Li et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Integrated Omics Reveals Tollip as an Aggravator and Therapeutic Target for Hepatic Ischemia‐Reperfusion Injury in Mice

(2019) Zhen‐Zhen Yan et al.   HEPATOLOGY

Silybin-Induced Apoptosis Occurs in Parallel to the Increase of Ceramides Synthesis and miRNAs Secretion in Human Hepatocarcinoma Cells

(2019) Silvia Zappavigna et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitochondrial DNA in liver inflammation and oxidative stress

(2019) Xufei Zhang et al.   LIFE SCIENCES

Immune checkpoint inhibitors for hepatocellular carcinoma

(2019) Imane El Dika et al.   CANCER

Hepatocyte TRAF6 Aggravates Hepatic Inflammation and Fibrosis by Promoting Lys6- Linked Polyubiquitination of ASK1

(2019) Yutao Wang et al.   HEPATOLOGY

Diet and Non-Alcoholic Fatty Liver Disease: The Mediterranean Way

(2019) Ludovico Abenavoli et al.   International Journal of Environmental Research and Public Health

Biochemical basis and metabolic interplay of redox regulation

(2019) Lixiao Zhang et al.   Redox Biology

The role of Toll‐like receptor 10 in modulation of trained immunity

(2019) Vera P. Mourits et al.   IMMUNOLOGY

Adaptive immunity: an emerging player in the progression of NAFLD

(2019) Salvatore Sutti et al.   Nature Reviews Gastroenterology & Hepatology

Emerging Molecular Targets for Treatment of Nonalcoholic Fatty Liver Disease

(2019) Ze Chen et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Itaconate modulates tricarboxylic acid and redox metabolism to mitigate reperfusion injury

(2019) Thekla Cordes et al.   Molecular Metabolism

Role of bisphenol A as environmental factor in the promotion of non-alcoholic fatty liver disease: in vitro and clinical study

(2018) M. Dallio et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Nonalcoholic Fatty Liver Disease as a Nexus of Metabolic and Hepatic Diseases

(2018) Varman T. Samuel et al.   Cell Metabolism

Reactive Oxygen Species in Metabolic and Inflammatory Signaling

(2018) Steven J. Forrester et al.   CIRCULATION RESEARCH

The Natural History of Nonalcoholic Fatty Liver Disease—An Evolving View

(2018) Christina C. Lindenmeyer et al.   Clinics in Liver Disease

The Global Epidemic of the Metabolic Syndrome

(2018) Mohammad G. Saklayen   CURRENT HYPERTENSION REPORTS

B2-Lymphocyte responses to oxidative stress-derived antigens contribute to the evolution of nonalcoholic fatty liver disease (NAFLD)

(2018) Stefania Bruzzì et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidative stress in autoimmune rheumatic diseases

(2018) Miranda J. Smallwood et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondria in non-alcoholic fatty liver disease

(2018) Inês C.M. Simões et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Mitochondrial dysfunction and damage associated molecular patterns (DAMPs) in chronic inflammatory diseases

(2018) Charles S. Dela Cruz et al.   MITOCHONDRION

Mechanisms of NAFLD development and therapeutic strategies

(2018) Scott L. Friedman et al.   NATURE MEDICINE

Role of Oxidative Stress in Pathophysiology of Nonalcoholic Fatty Liver Disease

(2018) Mario Masarone et al.   Oxidative Medicine and Cellular Longevity

Hepatic Dendritic Cells, the Tolerogenic Liver Environment, and Liver Disease

(2018) Lei Dou et al.   SEMINARS IN LIVER DISEASE

Carcinogenesis as a Result of Multiple Inflammatory and Oxidative Hits: a Comprehensive Review from Tumor Microenvironment to Gut Microbiota

(2018) Floriana Morgillo et al.   NEOPLASIA

Synergistic interaction of fatty acids and oxysterols impairs mitochondrial function and limits liver adaptation during nafld progression

(2018) Francesco Bellanti et al.   Redox Biology

Innate Immune Signaling in Nonalcoholic Fatty Liver Disease and Cardiovascular Diseases

(2018) Jingjing Cai et al.   Annual Review of Pathology-Mechanisms of Disease

Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis

(2018) Joel S Riley et al.   EMBO JOURNAL

N-Acetylcysteine Attenuates Progression of Liver Pathology in a Rat Model of Nonalcoholic Steatohepatitis

(2018) January N. Baumgardner et al.   JOURNAL OF NUTRITION

Electrophilic properties of itaconate and derivatives regulate the IκBζ–ATF3 inflammatory axis

(2018) Monika Bambouskova et al.   NATURE

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

(2018) Evanna L. Mills et al.   NATURE

Role of Innate Immune Signaling in Non-Alcoholic Fatty Liver Disease

(2018) Jingjing Cai et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Co-culture of dendritic cells and cytokine-induced killer cells effectively suppresses liver cancer stem cell growth by inhibiting pathways in the immune system

(2018) Tao Yang et al.   BMC CANCER

The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity

(2018) Jorge Domínguez-Andrés et al.   Cell Metabolism

Epidemiology and Management of Hepatocellular Carcinoma

(2018) Laura Kulik et al.   GASTROENTEROLOGY

Danger-Associated Molecular Patterns (DAMPs): Molecular Triggers for Sterile Inflammation in the Liver

(2018) Sabine Mihm   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nonalcoholic Fatty Liver Disease

(2018) Irene Pierantonelli et al.   TRANSPLANTATION

Insights into the Epidemiology, Pathogenesis, and Therapeutics of Nonalcoholic Fatty Liver Diseases

(2018) Yao Yu et al.   Advanced Science

New insights into oxidative stress and inflammation during diabetes mellitus-accelerated atherosclerosis

(2018) Ting Yuan et al.   Redox Biology

FXR controls CHOP expression in steatohepatitis

(2017) Claudia D. Fuchs et al.   FEBS LETTERS

Lipid oxidation products in the pathogenesis of non-alcoholic steatohepatitis

(2017) Francesco Bellanti et al.   FREE RADICAL BIOLOGY AND MEDICINE

The E3 ligase tripartite motif 8 targets TAK1 to promote insulin resistance and steatohepatitis

(2017) Feng-Juan Yan et al.   HEPATOLOGY

Reprogramming Innate Immune Signaling in Cardiometabolic Disease

(2017) Yaxing Zhang et al.   HYPERTENSION

Tmbim1 is a multivesicular body regulator that protects against non-alcoholic fatty liver disease in mice and monkeys by targeting the lysosomal degradation of Tlr4

(2017) Guang-Nian Zhao et al.   NATURE MEDICINE

Immuno-Oncology in Hepatocellular Carcinoma: 2017 Update

(2017) Masatoshi Kudo   ONCOLOGY

Oxidative Stress in Liver Diseases: Pathogenesis, Prevention, and Therapeutics

(2017) Ravirajsinh N. Jadeja et al.   Oxidative Medicine and Cellular Longevity

Dynamic plasticity of macrophage functions in diseased liver

(2017) Thomas Ritz et al.   CELLULAR IMMUNOLOGY

TRAIL regulatory receptors constrain human hepatic stellate cell apoptosis

(2017) Harsimran D. Singh et al.   Scientific Reports

Hepatic Oncostatin M Receptor β Regulates Obesity-Induced Steatosis and Insulin Resistance

(2016) Pengcheng Luo et al.   AMERICAN JOURNAL OF PATHOLOGY

Lipotoxicity in steatohepatitis occurs despite an increase in tricarboxylic acid cycle activity

(2016) Rainey E. Patterson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Low levels of IgM antibodies recognizing oxidation-specific epitopes are associated with human non-alcoholic fatty liver disease

(2016) Tim Hendrikx et al.   BMC Medicine

Assessment of Hepatic Mitochondrial Oxidation and Pyruvate Cycling in NAFLD by 13 C Magnetic Resonance Spectroscopy

(2016) Kitt Falk Petersen et al.   Cell Metabolism

Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation

(2016) Vicky Lampropoulou et al.   Cell Metabolism

Oxidative stress, polarization of macrophages and tumour angiogenesis: Efficacy of caffeic acid

(2016) Nada Oršolić et al.   CHEMICO-BIOLOGICAL INTERACTIONS

In VitroExperimental Model of Trained Innate Immunity in Human Primary Monocytes

(2016) Siroon Bekkering et al.   Clinical and Vaccine Immunology

Liver capsule: IRFs in hepatocytes: Pathophysiology

(2016) Pi-Xiao Wang et al.   HEPATOLOGY

The economic and clinical burden of nonalcoholic fatty liver disease in the United States and Europe

(2016) Zobair M. Younossi et al.   HEPATOLOGY

Tripartite Motif 8 Contributes to Pathological Cardiac Hypertrophy Through Enhancing Transforming Growth Factor β–Activated Kinase 1–Dependent Signaling PathwaysNovelty and Significance

(2016) Lijuan Chen et al.   HYPERTENSION

Hepatocyte mitochondrial DNA drives nonalcoholic steatohepatitis by activation of TLR9

(2016) Irma Garcia-Martinez et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting hepatic TRAF1-ASK1 signaling to improve inflammation, insulin resistance, and hepatic steatosis

(2016) Mei Xiang et al.   JOURNAL OF HEPATOLOGY

Targeting TRAF3 signaling protects against hepatic ischemia/reperfusions injury

(2016) Junfei Hu et al.   JOURNAL OF HEPATOLOGY

The role of macrophages in obesity-driven chronic liver disease

(2016) Lindsey Devisscher et al.   JOURNAL OF LEUKOCYTE BIOLOGY

CAFs and TAMs: maestros of the tumour microenvironment

(2016) Yoshihiro Komohara et al.   JOURNAL OF PATHOLOGY

The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)

(2016) Elena Buzzetti et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Superoxide Induces Neutrophil Extracellular Trap Formation in a TLR-4 and NOX-Dependent Mechanism

(2016) Ahmed B Al-Khafaji et al.   MOLECULAR MEDICINE

NAFLD causes selective CD4+ T lymphocyte loss and promotes hepatocarcinogenesis

(2016) Chi Ma et al.   NATURE

Insights into the Role and Interdependence of Oxidative Stress and Inflammation in Liver Diseases

(2016) Sha Li et al.   Oxidative Medicine and Cellular Longevity

TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway

(2016) Sébastien Viel et al.   Science Signaling

TNF and ROS Crosstalk in Inflammation

(2016) Heiko Blaser et al.   TRENDS IN CELL BIOLOGY

TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway

(2016) Sébastien Viel et al.   Science Signaling

Nonsteroidal Anti-inflammatory Drugs Are Associated With Reduced Risk of Early Hepatocellular Carcinoma Recurrence After Curative Liver Resection

(2015) Chun-Chieh Yeh et al.   ANNALS OF SURGERY

Interferon regulatory factors: at the crossroads of immunity, metabolism, and disease

(2015) Guang-Nian Zhao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Adaptation of Hepatic Mitochondrial Function in Humans with Non-Alcoholic Fatty Liver Is Lost in Steatohepatitis

(2015) Chrysi Koliaki et al.   Cell Metabolism

The balance between IL-17 and IL-22 produced by liver-infiltrating T-helper cells critically controls NASH development in mice

(2015) S. Rolla et al.   CLINICAL SCIENCE

Endoplasmic reticulum stress and Oxidative stress in the pathogenesis of Non-alcoholic fatty liver disease

(2015) N. U. Ashraf et al.   FREE RADICAL RESEARCH

Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization

(2015) Abhishek K. Jha et al.   IMMUNITY

Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver

(2015) Santhosh Satapati et al.   JOURNAL OF CLINICAL INVESTIGATION

The yin and yang of evasion and immune activation in HCC

(2015) Oxana V. Makarova-Rusher et al.   JOURNAL OF HEPATOLOGY

Interferon regulatory factor 9 is a key mediator of hepatic ischemia/reperfusion injury

(2015) Pi-Xiao Wang et al.   JOURNAL OF HEPATOLOGY

Progression from Nonalcoholic Fatty Liver to Nonalcoholic Steatohepatitis Is Marked by a Higher Frequency of Th17 Cells in the Liver and an Increased Th17/Resting Regulatory T Cell Ratio in Peripheral Blood and in the Liver

(2015) Monika Rau et al.   JOURNAL OF IMMUNOLOGY

The story of HCC in NAFLD: from epidemiology, across pathogenesis, to prevention and treatment

(2015) Cristina Margini et al.   LIVER INTERNATIONAL

T-cell exhaustion in the tumor microenvironment

(2015) Y Jiang et al.   Cell Death & Disease

Mitochondrial DNA in the regulation of innate immune responses

(2015) Chunju Fang et al.   Protein & Cell

Metabolic Regulation of Immune Responses

(2014) Kirthana Ganeshan et al.   Annual Review of Immunology

Endoplasmic Reticulum Stress and Oxidative Stress in Cell Fate Decision and Human Disease

(2014) Stewart Siyan Cao et al.   ANTIOXIDANTS & REDOX SIGNALING

ROS Function in Redox Signaling and Oxidative Stress

(2014) Michael Schieber et al.   CURRENT BIOLOGY

Stem cells and the impact of ROS signaling

(2014) C. L. Bigarella et al.   DEVELOPMENT

Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation

(2014) Jia Xue et al.   IMMUNITY

Emerging role of HMGB1 in fibrotic diseases

(2014) Liu-Cheng Li et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Hepatocyte free cholesterol lipotoxicity results from JNK1-mediated mitochondrial injury and is HMGB1 and TLR4-dependent

(2014) Lay T. Gan et al.   JOURNAL OF HEPATOLOGY

Mindin/Spondin 2 inhibits hepatic steatosis, insulin resistance, and obesity via interaction with peroxisome proliferator-activated receptor α in mice

(2014) Li-Hua Zhu et al.   JOURNAL OF HEPATOLOGY

Breaking immunotolerance of tumors: A new perspective for dendritic cell therapy

(2014) Jacek Rolinski et al.   Journal of Immunotoxicology

JNK interaction with Sab mediates ER stress induced inhibition of mitochondrial respiration and cell death

(2014) S Win et al.   Cell Death & Disease

Reactive Oxygen Species in Inflammation and Tissue Injury

(2013) Manish Mittal et al.   ANTIOXIDANTS & REDOX SIGNALING

ROS play a critical role in the differentiation of alternatively activated macrophages and the occurrence of tumor-associated macrophages

(2013) Yan Zhang et al.   CELL RESEARCH

CARD3 Deficiency Exacerbates Diet-Induced Obesity, Hepatosteatosis, and Insulin Resistance in Male Mice

(2013) Xin-An Wang et al.   ENDOCRINOLOGY

Free radical biology for medicine: learning from nonalcoholic fatty liver disease

(2013) Gaetano Serviddio et al.   FREE RADICAL BIOLOGY AND MEDICINE

Contribution of endogenously produced reactive oxygen species to the activation of podocyte NLRP3 inflammasomes in hyperhomocysteinemia

(2013) Justine M. Abais et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxysterols and redox signaling in the pathogenesis of non-alcoholic fatty liver disease

(2013) G. Serviddio et al.   FREE RADICAL RESEARCH

Adaptive immune responses triggered by oxidative stress contribute to hepatic inflammation in NASH

(2013) Salvatore Sutti et al.   HEPATOLOGY

Interferon regulatory factor 3 constrains IKKβ/NF-κB signaling to alleviate hepatic steatosis and insulin resistance

(2013) Xin-An Wang et al.   HEPATOLOGY

Necroptosis: The Release of Damage-Associated Molecular Patterns and Its Physiological Relevance

(2013) Agnieszka Kaczmarek et al.   IMMUNITY

Multiple Hits, Including Oxidative Stress, as Pathogenesis and Treatment Target in Non-Alcoholic Steatohepatitis (NASH)

(2013) Akinobu Takaki et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Reactive Oxygen Species in the Immune System

(2013) Yuhui Yang et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Hepatic stellate cells promote tumor progression by enhancement of immunosuppressive cells in an orthotopic liver tumor mouse model

(2013) Wenxiu Zhao et al.   LABORATORY INVESTIGATION

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

(2013) G. M. Tannahill et al.   NATURE

Regulation of NF-B-Induced Inflammatory Signaling by Lipid Peroxidation-Derived Aldehydes

(2013) Umesh C. S. Yadav et al.   Oxidative Medicine and Cellular Longevity

Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production

(2013) A. Michelucci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Candida albicans Infection Affords Protection against Reinfection via Functional Reprogramming of Monocytes

(2012) Jessica Quintin et al.   Cell Host & Microbe

Specific immunization strategies against oxidized low-density lipoprotein: A novel way to reduce nonalcoholic steatohepatitis in mice

(2012) Veerle Bieghs et al.   HEPATOLOGY

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

(2012) Simon Yona et al.   IMMUNITY

Dietary fatty acids modulate liver mitochondrial cardiolipin content and its fatty acid composition in rats with non alcoholic fatty liver disease

(2012) Manar Aoun et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

The Role of Innate Cells Is Coupled to a Th1-Polarized Immune Response in Pediatric Nonalcoholic Steatohepatitis

(2012) Nazarena E. Ferreyra Solari et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Elevated TCA cycle function in the pathology of diet-induced hepatic insulin resistance and fatty liver

(2012) Santhosh Satapati et al.   JOURNAL OF LIPID RESEARCH

Lipoic acid administration prevents nonalcoholic steatosis linked to long-term high-fat feeding by modulating mitochondrial function

(2012) M. Pilar Valdecantos et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Regulation of hepatic mitochondrial metabolism in response to a high fat diet: a longitudinal study in rats

(2012) Mélissa Flamment et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Nonsteroidal Anti-inflammatory Drug Use, Chronic Liver Disease, and Hepatocellular Carcinoma

(2012) Vikrant V. Sahasrabuddhe et al.   JNCI-Journal of the National Cancer Institute

Propionyl-L-carnitine Corrects Metabolic and Cardiovascular Alterations in Diet-Induced Obese Mice and Improves Liver Respiratory Chain Activity

(2012) Carmen Mingorance et al.   PLoS One

Bacille Calmette-Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes

(2012) J. Kleinnijenhuis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aberrant methylation ofSPARCin human hepatocellular carcinoma and its clinical implication

(2012) Ye Zhang   WORLD JOURNAL OF GASTROENTEROLOGY

The Inflammatory Microenvironment in Hepatocellular Carcinoma: A Pivotal Role for Tumor-Associated Macrophages

(2012) Daria Capece et al.   Biomed Research International

HMGB1 Is a Therapeutic Target for Sterile Inflammation and Infection

(2011) Ulf Andersson et al.   Annual Review of Immunology

High Mobility Group Box 1 (HMGB1) Activates an Autophagic Response to Oxidative Stress

(2011) Daolin Tang et al.   ANTIOXIDANTS & REDOX SIGNALING

Role of the microenvironment in hepatocellular carcinoma development and progression

(2011) Sheng-Di Wu et al.   CANCER TREATMENT REVIEWS

Oxidative Phosphorylation Flexibility in the Liver of Mice Resistant to High-Fat Diet-Induced Hepatic Steatosis

(2011) C. Poussin et al.   DIABETES

Elevated hepatic fatty acid oxidation, high plasma fibroblast growth factor 21, and fasting bile acids in nonalcoholic steatohepatitis

(2011) Srinivasan Dasarathy et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Crystal Structure of NALP3 Protein Pyrin Domain (PYD) and Its Implications in Inflammasome Assembly

(2011) Ju Young Bae et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Altered Phenotype and Functionality of Circulating Immune Cells Characterize Adult Patients with Nonalcoholic Steatohepatitis

(2011) María Eugenia Inzaugarat et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Increased hepatic apoptosis in high-fat diet-induced NASH in rats may be associated with downregulation of hepatic stimulator substance

(2011) Ying Jiang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Expression profile of human immune-responsive gene 1 and generation and characterization of polyclonal antiserum

(2011) Wei Xiao et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Oxidation of Hepatic Carnitine Palmitoyl Transferase-I (CPT-I) Impairs Fatty Acid Beta-Oxidation in Rats Fed a Methionine-Choline Deficient Diet

(2011) Gaetano Serviddio et al.   PLoS One

Mitochondrial dysfunction in nonalcoholic steatohepatitis

(2011) Gaetano Serviddio et al.   Expert Review of Gastroenterology & Hepatology

Greater dietary fat oxidation in obese compared with lean men: an adaptive mechanism to prevent liver fat accumulation?

(2010) Leanne Hodson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Crosstalk of reactive oxygen species and NF-κB signaling

(2010) Michael J Morgan et al.   CELL RESEARCH

Long-term High-fat-diet Feeding Impairs Mitochondrial Biogenesis in Liver of Male and Female Rats

(2010) Antònia Nadal-Casellas et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Hallmarks of cancer: Interactions with the tumor stroma

(2010) Kristian Pietras et al.   EXPERIMENTAL CELL RESEARCH

CTLA-4 is expressed by human monocyte—derived dendritic cells and regulates their functions

(2010) Stefania Laurent et al.   HUMAN IMMUNOLOGY

Oxidative stress parameters in paediatric non-alcoholic fatty liver disease

(2010) Nobili   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

The inflammatory microenvironment of HCC – The plot becomes complex

(2010) Jörg Schrader et al.   JOURNAL OF HEPATOLOGY

Effects of a high-fat diet on energy metabolism and ROS production in rat liver

(2010) Guillaume Vial et al.   JOURNAL OF HEPATOLOGY

Low-dose Cyclophosphamide Treatment Impairs Regulatory T Cells and Unmasks AFP-specific CD4+ T-cell Responses in Patients With Advanced HCC

(2010) Tim F. Greten et al.   JOURNAL OF IMMUNOTHERAPY

NF-κB, JNK, and TLR Signaling Pathways in Hepatocarcinogenesis

(2010) Shin Maeda   Gastroenterology Research and Practice

Glycine and urea kinetics in nonalcoholic steatohepatitis in human: effect of intralipid infusion

(2009) Srinivasan Dasarathy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Combination of peritumoral mast cells and T-regulatory cells predicts prognosis of hepatocellular carcinoma

(2009) Min-Jie Ju et al.   CANCER SCIENCE

Oxidation-specific epitopes are dominant targets of innate natural antibodies in mice and humans

(2009) Meng-Yun Chou et al.   JOURNAL OF CLINICAL INVESTIGATION

Inositol phosphatase SHIP1 is a primary target of miR-155

(2009) R. M. O'Connell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fatty liver and insulin resistance in obese Zucker rats: No role for mitochondrial dysfunction

(2008) Mélissa Flamment et al.   BIOCHIMIE

A New Population of Myeloid-Derived Suppressor Cells in Hepatocellular Carcinoma Patients Induces CD4+CD25+Foxp3+ T Cells

(2008) Bastian Hoechst et al.   GASTROENTEROLOGY

Induction of Immunological Tolerance by Apoptotic Cells Requires Caspase-Dependent Oxidation of High-Mobility Group Box-1 Protein

(2008) Hirotaka Kazama et al.   IMMUNITY

Chop deletion reduces oxidative stress, improves β cell function, and promotes cell survival in multiple mouse models of diabetes

(2008) Benbo Song et al.   JOURNAL OF CLINICAL INVESTIGATION

High Expression of Macrophage Colony-Stimulating Factor in Peritumoral Liver Tissue Is Associated With Poor Survival After Curative Resection of Hepatocellular Carcinoma

(2008) Xiao-Dong Zhu et al.   JOURNAL OF CLINICAL ONCOLOGY

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE

Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation

(2008) Y. Onishi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nonalcoholic Fatty Liver Disease: Pathogenesis and Potential for Nuclear Receptors as Therapeutic Targets

(2007) Jacob George et al.   MOLECULAR PHARMACEUTICS