Effect of GPR84 deletion on obesity and diabetes development in mice fed long chain or medium chain fatty acid rich diets

Weight-loss diet that includes consumption of medium-chain triacylglycerol oil leads to a greater rate of weight and fat mass loss than does olive oil

(2018) Marie-Pierre St-Onge et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Adipose tissue Mest and Sfrp5 are concomitant with variations of adiposity among inbred mouse strains fed a non-obesogenic diet

(2016) Rea P. Anunciado-Koza et al.   BIOCHIMIE

GPR84 deficiency reduces microgliosis, but accelerates dendritic degeneration and cognitive decline in a mouse model of Alzheimer’s disease

(2015) Julie Audoy-Rémus et al.   BRAIN BEHAVIOR AND IMMUNITY

Genetic Architecture of Insulin Resistance in the Mouse

(2015) Brian W. Parks et al.   Cell Metabolism

The Role of G-Protein Receptor 84 in Experimental Neuropathic Pain

(2015) L. S. C. Nicol et al.   JOURNAL OF NEUROSCIENCE

Identification of Glial Activation Markers by Comparison of Transcriptome Changes between Astrocytes and Microglia following Innate Immune Stimulation

(2015) Silvia Madeddu et al.   PLoS One

Medium-chain Fatty Acid-sensing Receptor, GPR84, Is a Proinflammatory Receptor

(2013) Masakatsu Suzuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Several Classical Mouse Inbred Strains, Including DBA/2, NOD/Lt, FVB/N, and SJL/J, Carry a Putative Loss-of-Function Allele of Gpr84

(2013) C. J. Perez et al.   JOURNAL OF HEREDITY

Contrasting metabolic effects of medium- versus long-chain fatty acids in skeletal muscle

(2013) Magdalene K. Montgomery et al.   JOURNAL OF LIPID RESEARCH

The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43

(2013) Ikuo Kimura et al.   Nature Communications

Male mice that lack the G-protein-coupled receptor GPR41 have low energy expenditure and increased body fat content

(2012) Mohamed Bellahcene et al.   BRITISH JOURNAL OF NUTRITION

Inflammatory changes in adipose tissue enhance expression of GPR84, a medium-chain fatty acid receptor

(2012) Hiroshi Nagasaki et al.   FEBS LETTERS

Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human

(2012) Atsuhiko Ichimura et al.   NATURE

Improved glucose control and reduced body fat mass in free fatty acid receptor 2-deficient mice fed a high-fat diet

(2010) Mikael Bjursell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects

(2010) Da Young Oh et al.   CELL

High-fat diets rich in medium- versus long-chain fatty acids induce distinct patterns of tissue specific insulin resistance

(2010) Johan De Vogel-van den Bosch et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Deletion of GPR40 Impairs Glucose-Induced Insulin Secretion In Vivo in Mice Without Affecting Intracellular Fuel Metabolism in Islets

(2009) T. Alquier et al.   DIABETES

Enhancement of Muscle Mitochondrial Oxidative Capacity and Alterations in Insulin Action Are Lipid Species Dependent: Potent Tissue-Specific Effects of Medium-Chain Fatty Acids

(2009) N. Turner et al.   DIABETES

Induction of proinflammatory cytokines by long-chain saturated fatty acids in human macrophages

(2008) Liliana Håversen et al.   ATHEROSCLEROSIS

Lack of FFAR1/GPR40 Does Not Protect Mice From High-Fat Diet-Induced Metabolic Disease

(2008) H. Lan et al.   DIABETES