Novel insights into the function and dynamics of extracellular matrix in liver fibrosis

Macrophage Activation in Acute Exacerbation of Idiopathic Pulmonary Fibrosis

(2015) Jonas Christian Schupp et al.   PLoS One

Novel serological neo-epitope markers of extracellular matrix proteins for the detection of portal hypertension

(2015) D. J. Leeming et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Review article: the efficacy of biomarkers in chronic fibroproliferative diseases - early diagnosis and prognosis, with liver fibrosis as an exemplar

(2014) M. A. Karsdal et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Increasing matrix stiffness upregulates vascular endothelial growth factor expression in hepatocellular carcinoma cells mediated by integrin β1

(2014) Yinying Dong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Overexpression of DDR2 contributes to cell invasion and migration in head and neck squamous cell carcinoma

(2014) Jinke Xu et al.   CANCER BIOLOGY & THERAPY

Hedgehog signaling pathway as key player in liver fibrosis: new insights and perspectives

(2014) Jing-Jing Yang et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

OC-033 The Tweak And Fn14 Pathway As Potential Mediator Of Liver Fibrosis

(2014) A Wilhelm et al.   GUT

Angiotensin-II type 1 receptor-mediated Janus kinase 2 activation induces liver fibrosis

(2014) Michaela Granzow et al.   HEPATOLOGY

Polysialic acid/neural cell adhesion molecule modulates the formation of ductular reactions in liver injury

(2014) Atsunori Tsuchiya et al.   HEPATOLOGY

Lysyl oxidase-like 2 is critical to tumor microenvironment and metastatic niche formation in hepatocellular carcinoma

(2014) Carmen Chak-Lui Wong et al.   HEPATOLOGY

Novel Aspects of the Liver Microenvironment in Hepatocellular Carcinoma Pathogenesis and Development

(2014) Thomas Tu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Treatment of Hepatitis C

(2014) Anita Kohli et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Collagen receptors integrin alpha2beta1 and discoidin domain receptor 1 regulate maturation of the glomerular basement membrane and loss of integrin alpha2beta1 delays kidney fibrosis in COL4A3 knockout mice

(2014) Diana Rubel et al.   MATRIX BIOLOGY

Inhibition of fibroblast growth factor receptor signaling impairs metastasis of hepatocellular carcinoma

(2014) Jiajun Wang et al.   TUMOR BIOLOGY

Chronic hepatitis B in 2014: Great therapeutic progress, large diagnostic deficit

(2014) Claus Niederau   WORLD JOURNAL OF GASTROENTEROLOGY

Inhibition of breast cancer growth and metastasis by a biomimetic peptide

(2014) Esak Lee et al.   Scientific Reports

Antiviral treatment of hepatitis C

(2014) E. R. Feeney et al.   BMJ-British Medical Journal

Incomplete Deletion of IL-4Rα by LysMCre Reveals Distinct Subsets of M2 Macrophages Controlling Inflammation and Fibrosis in Chronic Schistosomiasis

(2014) Kevin M. Vannella et al.   PLoS Pathogens

C-Terminal Agrin Fragment - A New Fast Biomarker for Kidney Function in Renal Transplant Recipients

(2013) Dominik Steubl et al.   AMERICAN JOURNAL OF NEPHROLOGY

Fibronectin contributes to pathological cardiac hypertrophy but not physiological growth

(2013) Mathias H. Konstandin et al.   BASIC RESEARCH IN CARDIOLOGY

From tissue mechanics to transcription factors

(2013) Paul A. Janmey et al.   DIFFERENTIATION

Type XVIII collagen is essential for survival during acute liver injury in mice

(2013) M. B. Duncan et al.   Disease Models & Mechanisms

Fibroblast morphogenesis on 3D collagen matrices: The balance between cell clustering and cell migration

(2013) Bruno da Rocha-Azevedo et al.   EXPERIMENTAL CELL RESEARCH

In the beginning there were soft collagen-cell gels: towards better 3D connective tissue models?

(2013) Robert A. Brown   EXPERIMENTAL CELL RESEARCH

Decorin interferes with platelet-derived growth factor receptor signaling in experimental hepatocarcinogenesis

(2013) Kornélia Baghy et al.   FEBS Journal

Discoidin Domain Receptors: Unique Receptor Tyrosine Kinases in Collagen-mediated Signaling

(2013) Hsueh-Liang Fu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evolving therapies for liver fibrosis

(2013) Detlef Schuppan et al.   JOURNAL OF CLINICAL INVESTIGATION

Non-alcoholic steatohepatitis: Pathogenesis and novel therapeutic approaches

(2013) Detlef Schuppan et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Notch signaling and new therapeutic options in liver disease

(2013) Carola Maria Morell et al.   JOURNAL OF HEPATOLOGY

Liver fibrosis progression at autopsy in injecting drug users infected by hepatitis C: A longitudinal long-term cohort study

(2013) Knut Boe Kielland et al.   JOURNAL OF HEPATOLOGY

Long-Term Survival of Type XVII Collagen Revertant Cells in an Animal Model of Revertant Cell Therapy

(2013) Antoni Gostyński et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Mesenchymal stem cells and Interleukin-6 attenuate liver fibrosis in mice

(2013) Ghazanfar Ali Nasir et al.   Journal of Translational Medicine

Discoidin domain receptors in disease

(2013) Corina M. Borza et al.   MATRIX BIOLOGY

Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

Endostatin, an angiogenesis inhibitor, ameliorates bleomycin-induced pulmonary fibrosis in rats

(2013) Yun-Yan Wan et al.   RESPIRATORY RESEARCH

Therapy for Fibrotic Diseases: Nearing the Starting Line

(2013) S. L. Friedman et al.   Science Translational Medicine

Advances in cholangiocyte immunobiology

(2012) Gaurav Syal et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Host Responses in Tissue Repair and Fibrosis

(2012) Jeremy S. Duffield et al.   Annual Review of Pathology-Mechanisms of Disease

Extracellular Matrix Remodeling: The Common Denominator in Connective Tissue DiseasesPossibilities for Evaluation and Current Understanding of the Matrix as More Than a Passive Architecture, but a Key Player in Tissue Failure

(2012) Morten A. Karsdal et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Discoidin domain receptor tyrosine kinases: new players in cancer progression

(2012) Rajeshwari R. Valiathan et al.   CANCER AND METASTASIS REVIEWS

MMP mediated type V collagen degradation (C5M) is elevated in ankylosing spondylitis

(2012) S.S. Veidal et al.   CLINICAL BIOCHEMISTRY

Prevalence and Natural History of Alcoholic Liver Disease

(2012) Jonathan M. Schwartz et al.   Clinics in Liver Disease

Conformational switch of a flexible loop in human laminin receptor determines laminin-1 interaction

(2012) Carmen Di Giovanni et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Deactivation of Hepatic Stellate Cells During Liver Fibrosis Resolution in Mice

(2012) Juliane S. Troeger et al.   GASTROENTEROLOGY

Expression of 67-kDa laminin receptor was associated with tumor progression and poor prognosis in epithelial ovarian cancer

(2012) Taejong Song et al.   GYNECOLOGIC ONCOLOGY

Fibronectin and stem cell differentiation - lessons from chondrogenesis

(2012) P. Singh et al.   JOURNAL OF CELL SCIENCE

Macrophages: Central regulators of hepatic fibrogenesis and fibrosis resolution

(2012) Prakash Ramachandran et al.   JOURNAL OF HEPATOLOGY

Anti-fibrotic therapy: Lost in translation?

(2012) Detlef Schuppan et al.   JOURNAL OF HEPATOLOGY

Progression of liver fibrosis in post-transplant hepatitis C: Mechanisms, assessment and treatment

(2012) Marina Berenguer et al.   JOURNAL OF HEPATOLOGY

Lumican, an extracellular matrix proteoglycan, is a novel requisite for hepatic fibrosis

(2012) Anuradha Krishnan et al.   LABORATORY INVESTIGATION

Regression of cirrhosis during treatment with tenofovir disoproxil fumarate for chronic hepatitis B: a 5-year open-label follow-up study

(2012) Patrick Marcellin et al.   LANCET

Protein fingerprinting of the extracellular matrix remodelling in a rat model of liver fibrosis-a serological evaluation

(2012) Diana J. Leeming et al.   LIVER INTERNATIONAL

Tumor suppression by collagen XV is independent of the restin domain

(2012) Michael J. Mutolo et al.   MATRIX BIOLOGY

Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease

(2012) Luke Boulter et al.   NATURE MEDICINE

IgG4-Related Disease

(2012) John H. Stone et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inhibition of Notch Signaling by a γ-Secretase Inhibitor Attenuates Hepatic Fibrosis in Rats

(2012) Yixiong Chen et al.   PLoS One

Discoidin Domain Receptors Promote α1β1- and α2β1-Integrin Mediated Cell Adhesion to Collagen by Enhancing Integrin Activation

(2012) Huifang Xu et al.   PLoS One

Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis

(2012) T. Kisseleva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Peptide Derived from Endostatin Ameliorates Organ Fibrosis

(2012) Y. Yamaguchi et al.   Science Translational Medicine

The adipokine adiponectin has potent anti-fibrotic effects mediated via adenosine monophosphate-activated protein kinase: novel target for fibrosis therapy

(2012) Feng Fang et al.   ARTHRITIS RESEARCH & THERAPY

Discoidin Domain Receptor 1 Is a Major Mediator of Inflammation and Fibrosis in Obstructive Nephropathy

(2011) Dominique Guerrot et al.   AMERICAN JOURNAL OF PATHOLOGY

Loss of Discoidin Domain Receptor 2 Promotes Hepatic Fibrosis after Chronic Carbon Tetrachloride through Altered Paracrine Interactions between Hepatic Stellate Cells and Liver-Associated Macrophages

(2011) Elvira Olaso et al.   AMERICAN JOURNAL OF PATHOLOGY

Role of integrins in fibrosing liver diseases

(2011) Eleonora Patsenker et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Transglutaminase 2 and Its Role in Pulmonary Fibrosis

(2011) Keith C. Olsen et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Mechanisms of hepatic fibrogenesis

(2011) Ursula E. Lee et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assembly in the endothelial basement membrane

(2011) M. Bignon et al.   BLOOD

Development and validation of an enzyme-linked immunosorbent assay for the quantification of a specific MMP-9 mediated degradation fragment of type III collagen—A novel biomarker of atherosclerotic plaque remodeling

(2011) Natasha Barascuk et al.   CLINICAL BIOCHEMISTRY

Changes in the Prevalence of the Most Common Causes of Chronic Liver Diseases in the United States From 1988 to 2008

(2011) Zobair M. Younossi et al.   Clinical Gastroenterology and Hepatology

Lysyl oxidase-like 2 (LOXL2), a new regulator of cell polarity required for metastatic dissemination of basal-like breast carcinomas

(2011) Gema Moreno-Bueno et al.   EMBO Molecular Medicine

Macrophage activation governs schistosomiasis-induced inflammation and fibrosis

(2011) Luke Barron et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The potential for LOXL2 as a target for future cancer treatment

(2011) Holly E Barker et al.   Future Oncology

Tissue Transglutaminase Does Not Affect Fibrotic Matrix Stability or Regression of Liver Fibrosis in Mice

(2011) Yury Popov et al.   GASTROENTEROLOGY

Fibromodulin, an Oxidative Stress-Sensitive Proteoglycan, Regulates the Fibrogenic Response to Liver Injury in Mice

(2011) Elisabetta Mormone et al.   GASTROENTEROLOGY

Tenascin-C: A novel mediator of hepatic ischemia and reperfusion injury

(2011) Naohisa Kuriyama et al.   HEPATOLOGY

Critical role of tumor necrosis factor receptor 1, but not 2, in hepatic stellate cell proliferation, extracellular matrix remodeling, and liver fibrogenesis

(2011) Núria Tarrats et al.   HEPATOLOGY

Macrophage therapy for murine liver fibrosis recruits host effector cells improving fibrosis, regeneration, and function

(2011) James A. Thomas et al.   HEPATOLOGY

Pseudoachondroplasia and multiple epiphyseal dysplasia: A 7-year comprehensive analysis of the known disease genes identify novel and recurrent mutations and provides an accurate assessment of their relative contribution

(2011) Gail C. Jackson et al.   HUMAN MUTATION

Collagen I Induces Discoidin Domain Receptor (DDR) 1 Expression through DDR2 and a JAK2-ERK1/2-mediated Mechanism in Primary Human Lung Fibroblasts

(2011) Pedro A. Ruiz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CXCL9 and CXCL10 Chemokines as Predictors of Liver Fibrosis in a Cohort of Primarily African-American Injection Drug Users With Chronic Hepatitis C

(2011) Marija Zeremski et al.   JOURNAL OF INFECTIOUS DISEASES

Schmid-type metaphyseal chondrodysplasia as the result of a collagen type X defect due to a novel COL10A1 nonsense mutation

(2011) Julia V. Woelfle et al.   JOURNAL OF ORTHOPAEDIC SCIENCE

Small Leucine-Rich Proteoglycans in Kidney Disease

(2011) L. Schaefer   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

How to assess liver fibrosis in chronic hepatitis C: serum markers or transient elastography vs. liver biopsy?

(2011) Laurent Castera et al.   LIVER INTERNATIONAL

Hepatic stellate cells produce vascular endothelial growth factor via phospho-p44/42 mitogen–activated protein kinase/cyclooxygenase-2 pathway

(2011) Yi Zhao et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Syndecan-2 is a novel ligand for the protein tyrosine phosphatase receptor CD148

(2011) James R. Whiteford et al.   MOLECULAR BIOLOGY OF THE CELL

Tendon Is Covered by a Basement Membrane Epithelium That Is Required for Cell Retention and the Prevention of Adhesion Formation

(2011) Susan H. Taylor et al.   PLoS One

Role of Glomerular Proteoglycans in IgA Nephropathy

(2011) Kerstin Ebefors et al.   PLoS One

Interleukin-8 Is Activated in Patients with Chronic Liver Diseases and Associated with Hepatic Macrophage Accumulation in Human Liver Fibrosis

(2011) Henning W. Zimmermann et al.   PLoS One

Hedgehog Signaling Antagonist Promotes Regression of Both Liver Fibrosis and Hepatocellular Carcinoma in a Murine Model of Primary Liver Cancer

(2011) George M. Philips et al.   PLoS One

Tenascin-C fragments are endogenous inducers of cartilage matrix degradation

(2011) Nidhi Sofat et al.   RHEUMATOLOGY INTERNATIONAL

Tenascins and the Importance of Adhesion Modulation

(2011) R. Chiquet-Ehrismann et al.   Cold Spring Harbor Perspectives in Biology

Fibronectins, Their Fibrillogenesis, and In Vivo Functions

(2011) J. E. Schwarzbauer et al.   Cold Spring Harbor Perspectives in Biology

Animal models of Williams syndrome

(2010) Lucy R. Osborne   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Macrophage-mediated phagocytosis of apoptotic cholangiocytes contributes to reversal of experimental biliary fibrosis

(2010) Yury Popov et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

A family with a new elastin gene mutation: broad clinical spectrum, including sudden cardiac death

(2010) André Jakob et al.   CARDIOLOGY IN THE YOUNG

Haploinsufficiency of the murine Col3a1 locus causes aortic dissection: a novel model of the vascular type of Ehlers–Danlos syndrome

(2010) Lee B. Smith et al.   CARDIOVASCULAR RESEARCH

A novel assay for extracellular matrix remodeling associated with liver fibrosis: An enzyme-linked immunosorbent assay (ELISA) for a MMP-9 proteolytically revealed neo-epitope of type III collagen

(2010) N. Barascuk et al.   CLINICAL BIOCHEMISTRY

Novel combinations of Post-Translational Modification (PTM) neo-epitopes provide tissue-specific biochemical markers—are they the cause or the consequence of the disease?

(2010) Morten Asser Karsdal et al.   CLINICAL BIOCHEMISTRY

The changing pattern of epidemiology in hepatocellular carcinoma

(2010) Helena Nordenstedt et al.   DIGESTIVE AND LIVER DISEASE

Increasing Prevalence of HCC and Cirrhosis in Patients With Chronic Hepatitis C Virus Infection

(2010) Fasiha Kanwal et al.   GASTROENTEROLOGY

The Epidemiology of Obesity

(2010) Dang M. Nguyen et al.   GASTROENTEROLOGY CLINICS OF NORTH AMERICA

Remodelling of extracellular matrix is a requirement for the hepatic progenitor cell response

(2010) Y. N. Kallis et al.   GUT

Tumor necrosis factor-like weak inducer of apoptosis is a mitogen for liver progenitor cells

(2010) Janina E. E. Tirnitz-Parker et al.   HEPATOLOGY

The incidence and risk factors of hepatocellular carcinoma in patients with nonalcoholic steatohepatitis

(2010) Mustafa S. Ascha et al.   HEPATOLOGY

Matrix stiffness modulates proliferation, chemotherapeutic response, and dormancy in hepatocellular carcinoma cells

(2010) Jörg Schrader et al.   HEPATOLOGY

Anti-PDGF-B monoclonal antibody reduces liver fibrosis development

(2010) Shinji Ogawa et al.   HEPATOLOGY RESEARCH

Col4a1 mutation in mice causes defects in vascular function and low blood pressure associated with reduced red blood cell volume

(2010) Tom Van Agtmael et al.   HUMAN MOLECULAR GENETICS

CXCL10 promotes liver fibrosis by prevention of NK cell mediated hepatic stellate cell inactivation

(2010) Edith Hintermann et al.   JOURNAL OF AUTOIMMUNITY

Modulation of Lysyl Oxidase-like 2 Enzymatic Activity by an Allosteric Antibody Inhibitor

(2010) Hector M. Rodriguez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Knockdown of Zebrafish Lumican Gene (zlum) Causes Scleral Thinning and Increased Size of Scleral Coats

(2010) Lung-Kun Yeh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fibromodulin Suppresses Nuclear Factor-κB Activity by Inducing the Delayed Degradation of IKBA via a JNK-dependent Pathway Coupled to Fibroblast Apoptosis

(2010) Yong-Hun Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Syndecan-1 couples the insulin-like growth factor-1 receptor to inside-out integrin activation

(2010) D. M. Beauvais et al.   JOURNAL OF CELL SCIENCE

Early-onset metaphyseal chondrodysplasia type Schmid associated with a COL10A1 frame-shift mutation and impaired trimerization of wild-type α1(X) protein chains

(2010) Outi Mäkitie et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Ablation of the decorin gene enhances experimental hepatic fibrosis and impairs hepatic healing in mice

(2010) Kornélia Baghy et al.   LABORATORY INVESTIGATION

The multiple functions of collagen XVIII in development and disease

(2010) Lotta Seppinen et al.   MATRIX BIOLOGY

Collagen binding specificity of the discoidin domain receptors: Binding sites on collagens II and III and molecular determinants for collagen IV recognition by DDR1

(2010) Huifang Xu et al.   MATRIX BIOLOGY

The human lysyl oxidase-like 2 protein functions as an amine oxidase toward collagen and elastin

(2010) Young-Mi Kim et al.   MOLECULAR BIOLOGY REPORTS

Allosteric inhibition of lysyl oxidase–like-2 impedes the development of a pathologic microenvironment

(2010) Vivian Barry-Hamilton et al.   NATURE MEDICINE

Do changes in transglutaminase activity alter latent transforming growth factor beta activation in experimental diabetic nephropathy?

(2010) Linghong Huang et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

A New Mouse Model for Marfan Syndrome Presents Phenotypic Variability Associated with the Genetic Background and Overall Levels of Fbn1 Expression

(2010) Bruno L. Lima et al.   PLoS One

Macrophages: Master Regulators of Inflammation and Fibrosis

(2010) Thomas Wynn et al.   SEMINARS IN LIVER DISEASE

Basement Membranes: Cell Scaffoldings and Signaling Platforms

(2010) P. D. Yurchenco   Cold Spring Harbor Perspectives in Biology

Decreased physical function and increased pain sensitivity in mice deficient for type IX collagen

(2009) Kyle D. Allen et al.   ARTHRITIS AND RHEUMATISM

Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activity

(2009) A. Nystrom et al.   BLOOD

Secreted LOXL2 is a novel therapeutic target that promotes gastric cancer metastasis via the Src/FAK pathway

(2009) Liang Peng et al.   CARCINOGENESIS

Basement membranes and human disease

(2009) Tom Van Agtmael et al.   CELL AND TISSUE RESEARCH

Hepatic fibrosis

(2009) Jingjing Jiao et al.   CURRENT OPINION IN GASTROENTEROLOGY

Transglutaminases in inflammation and fibrosis of the gastrointestinal tract and the liver

(2009) L. Elli et al.   DIGESTIVE AND LIVER DISEASE

Kupffer Cells Mediate Leptin-Induced Liver Fibrosis

(2009) Jianhua Wang et al.   GASTROENTEROLOGY

Antifibrotic Effects of CXCL9 and Its Receptor CXCR3 in Livers of Mice and Humans

(2009) Hermann E. Wasmuth et al.   GASTROENTEROLOGY

Characterisation of the liver progenitor cell niche in liver diseases: potential involvement of Wnt and Notch signalling

(2009) B. Spee et al.   GUT

Targeting liver fibrosis: Strategies for development and validation of antifibrotic therapies

(2009) Yury Popov et al.   HEPATOLOGY

CCR2 promotes hepatic fibrosis in mice

(2009) Ekihiro Seki et al.   HEPATOLOGY

The predictors of the presence of varices in patients with primary sclerosing cholangitis

(2009) Sombat Treeprasertsuk et al.   HEPATOLOGY

Extracellular Matrix Lumican Deposited on the Surface of Neutrophils Promotes Migration by Binding to β2Integrin

(2009) Seakwoo Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biglycan, a Danger Signal That Activates the NLRP3 Inflammasome via Toll-like and P2X Receptors

(2009) Andrea Babelova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cells in 3D matrices under interstitial flow: Effects of extracellular matrix alignment on cell shear stress and drag forces

(2009) John A. Pedersen et al.   JOURNAL OF BIOMECHANICS

Decorin is a novel antagonistic ligand of the Met receptor

(2009) Silvia Goldoni et al.   JOURNAL OF CELL BIOLOGY

Syndecan-1 regulates αvβ3and αvβ5integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor

(2009) DeannaLee M. Beauvais et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Transglutaminase inhibition ameliorates experimental diabetic nephropathy

(2009) Linghong Huang et al.   KIDNEY INTERNATIONAL

Transglutaminases and Disease: Lessons From Genetically Engineered Mouse Models and Inherited Disorders

(2009) Siiri E. Iismaa et al.   PHYSIOLOGICAL REVIEWS

The Extracellular Matrix: Not Just Pretty Fibrils

(2009) R. O. Hynes   SCIENCE

Hepatocellular carcinoma: current trends in worldwide epidemiology, risk factors, diagnosis and therapeutics

(2009) Mohamed IF Shariff et al.   Expert Review of Gastroenterology & Hepatology

The matricellular functions of small leucine-rich proteoglycans (SLRPs)

(2009) Rosetta Merline et al.   Journal of Cell Communication and Signaling

Genetic deficiency of decorin causes intestinal tumor formation through disruption of intestinal cell maturation

(2008) X. Bi et al.   CARCINOGENESIS

The Potential Functional Interaction of Biglycan and WISP-1 in Controlling Differentiation and Proliferation of Osteogenic Cells

(2008) Colette A. Inkson et al.   CELLS TISSUES ORGANS

Discoidin Domain Receptor 1 ( Ddr1 ) Deletion Decreases Atherosclerosis by Accelerating Matrix Accumulation and Reducing Inflammation in Low-Density Lipoprotein Receptor–Deficient Mice

(2008) Christopher Franco et al.   CIRCULATION RESEARCH

Collagen fibrillogenesis: fibronectin, integrins, and minor collagens as organizers and nucleators

(2008) Karl E Kadler et al.   CURRENT OPINION IN CELL BIOLOGY

Decorin-Mediated Inhibition of Proliferation and Migration of the Human Trophoblast via Different Tyrosine Kinase Receptors

(2008) D. Iacob et al.   ENDOCRINOLOGY

Mutation analysis and characterization of COL7A1 mutations in dystrophic epidermolysis bullosa

(2008) Ningning Dang et al.   EXPERIMENTAL DERMATOLOGY

Inhibition of Integrin αvβ6 on Cholangiocytes Blocks Transforming Growth Factor-β Activation and Retards Biliary Fibrosis Progression

(2008) Eleonora Patsenker et al.   GASTROENTEROLOGY

Incidence of Hepatocellular Carcinoma and Associated Risk Factors in Hepatitis C-Related Advanced Liver Disease

(2008) Anna S. Lok et al.   GASTROENTEROLOGY

Evidence of a dosage effect and a physiological endplate acetylcholinesterase deficiency in the first mouse models mimicking Schwartz–Jampel syndrome neuromyotonia

(2008) Morgane Stum et al.   HUMAN MOLECULAR GENETICS

Neutrophil Elastase Cleaves Laminin-332 (Laminin-5) Generating Peptides That Are Chemotactic for Neutrophils

(2008) Piotr Mydel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decorin Regulates Endothelial Cell Motility on Collagen I through Activation of Insulin-like Growth Factor I Receptor and Modulation of α2β1 Integrin Activity

(2008) Lorna R. Fiedler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caspase-3 Activation Triggers Extracellular Cathepsin L Release and Endorepellin Proteolysis

(2008) Jean-François Cailhier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endostatin and anastellin inhibit distinct aspects of the angiogenic process

(2008) David M Neskey et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Molecular mechanism of hepatic stellate cell activation and antifibrotic therapeutic strategies

(2008) Jing-Ting Li et al.   JOURNAL OF GASTROENTEROLOGY

Integrin αvβ6 is a marker of the progression of biliary and portal liver fibrosis and a novel target for antifibrotic therapies

(2008) Yury Popov et al.   JOURNAL OF HEPATOLOGY

Dermatan sulfate proteoglycan biglycan as a potential selectin L/CD44 ligand involved in selective recruitment of peripheral blood CD16(−) natural killer cells into human endometrium

(2008) Kotaro Kitaya et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Platelet-derived growth factor isoform expression in carbon tetrachloride-induced chronic liver injury

(2008) Erawan Borkham-Kamphorst et al.   LABORATORY INVESTIGATION

Liver cirrhosis

(2008) Detlef Schuppan et al.   LANCET

Novel interactions of perlecan: Unraveling perlecan's role in angiogenesis

(2008) Gregory Bix et al.   MICROSCOPY RESEARCH AND TECHNIQUE

Short leucine-rich glycoproteins of the extracellular matrix display diverse patterns of complement interaction and activation

(2008) Andreas P. Sjöberg et al.   MOLECULAR IMMUNOLOGY

The cancer biomarker problem

(2008) Charles L. Sawyers   NATURE

Mining the plasma proteome for cancer biomarkers

(2008) Samir M. Hanash et al.   NATURE

Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver

(2008) Scott L. Friedman   PHYSIOLOGICAL REVIEWS

Extracellular Transglutaminase 2 Is Catalytically Inactive, but Is Transiently Activated upon Tissue Injury

(2008) Matthew Siegel et al.   PLoS One

Can cancer be reversed by engineering the tumor microenvironment?

(2008) Donald E. Ingber   SEMINARS IN CANCER BIOLOGY

Wnt antagonism inhibits hepatic stellate cell activation and liver fibrosis

(2007) Jason H. Cheng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Cellular and molecular mechanisms of fibrosis

(2007) TA Wynn   JOURNAL OF PATHOLOGY