Toll-like Receptor 4 on Macrophage Promotes the Development of Steatohepatitis-related Hepatocellular Carcinoma in Mice

Tumor-associated macrophages promote cancer stem cell-like properties via transforming growth factor-beta1-induced epithelial–mesenchymal transition in hepatocellular carcinoma

(2014) Qing-Min Fan et al.   CANCER LETTERS

Macrophage heterogeneity in liver injury and fibrosis

(2014) Frank Tacke et al.   JOURNAL OF HEPATOLOGY

Role of gut microbiota and Toll-like receptors in nonalcoholic fatty liver disease

(2014) Kouichi Miura   WORLD JOURNAL OF GASTROENTEROLOGY

Identification of Liver Cancer Progenitors Whose Malignant Progression Depends on Autocrine IL-6 Signaling

(2013) Guobin He et al.   CELL

Role of the Microenvironment in the Pathogenesis and Treatment of Hepatocellular Carcinoma

(2013) Virginia Hernandez–Gea et al.   GASTROENTEROLOGY

Toll-like receptor 4 activity protects against hepatocellular tumorigenesis and progression by regulating expression of DNA repair protein Ku70 in mice

(2013) Ziyan Wang et al.   HEPATOLOGY

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

(2013) Shin Yoshimoto et al.   NATURE

Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR2

(2012) Kouichi Miura et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Promotion of Hepatocellular Carcinoma by the Intestinal Microbiota and TLR4

(2012) Dianne H. Dapito et al.   CANCER CELL

Epidemiology of Viral Hepatitis and Hepatocellular Carcinoma

(2012) Hashem B. El-Serag   GASTROENTEROLOGY

Toll-like receptor 2 and palmitic acid cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation in mice

(2012) Kouichi Miura et al.   HEPATOLOGY

Discrete nature of EpCAM+and CD90+cancer stem cells in human hepatocellular carcinoma

(2012) Taro Yamashita et al.   HEPATOLOGY

Kuppfer Cells Trigger Nonalcoholic Steatohepatitis Development in Diet-induced Mouse Model through Tumor Necrosis Factor-α Production

(2012) Annie-Carole Tosello-Trampont et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Hepatocellular carcinoma

(2012) Alejandro Forner et al.   LANCET

Effects of green tea consumption on human fecal microbiota with special reference toBifidobacteriumspecies

(2012) Jong-Sik Jin et al.   MICROBIOLOGY AND IMMUNOLOGY

Pharmacological inhibition of the chemokine CCL2 (MCP-1) diminishes liver macrophage infiltration and steatohepatitis in chronic hepatic injury

(2011) Christer Baeck et al.   GUT

Toll-like receptor-2 deficiency enhances non-alcoholic steatohepatitis

(2010) Chantal A Rivera et al.   BMC GASTROENTEROLOGY

Dietary and Genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression

(2010) Eek Joong Park et al.   CELL

Expansion of Hepatic Tumor Progenitor Cells in Pten-Null Mice Requires Liver Injury and Is Reversed by Loss of AKT2

(2010) Vivian A. Galicia et al.   GASTROENTEROLOGY

Toll-Like Receptor 9 Promotes Steatohepatitis by Induction of Interleukin-1β in Mice

(2010) Kouichi Miura et al.   GASTROENTEROLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Potential hepatic stem cells reside in EpCAM+ cells of normal and injured mouse liver

(2009) M. Okabe et al.   DEVELOPMENT

Tlr2 is critical for diet-induced metabolic syndrome in a murine model

(2009) Ryan W. Himes et al.   FASEB JOURNAL

Lipopolysaccharide triggered TNF-α-induced hepatocyte apoptosis in a murine non-alcoholic steatohepatitis model

(2009) Hiroshi Kudo et al.   JOURNAL OF HEPATOLOGY

Liver Cancer Stem Cells

(2008) Stewart Sell et al.   JOURNAL OF CLINICAL ONCOLOGY

Expansion of CD133-Expressing Liver Cancer Stem Cells in Liver-Specific Phosphatase and Tensin Homolog Deleted on Chromosome 10-Deleted Mice

(2008) C. Bart Rountree et al.   STEM CELLS