Lipid metabolism in sickness and in health: Emerging regulators of lipotoxicity

Targeting a Braf/Mapk pathway rescues podocyte lipid peroxidation in CoQ-deficiency kidney disease

(2021) Eriene-Heidi Sidhom et al.   JOURNAL OF CLINICAL INVESTIGATION

APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia

(2021) Grzegorz Sienski et al.   Science Translational Medicine

Acetyl-CoA and Metabolite Fluxes Regulate White Adipose Tissue Expansion

(2021) Jessica B. Felix et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Reducing FASN expression sensitizes acute myeloid leukemia cells to differentiation therapy

(2021) Magali Humbert et al.   CELL DEATH AND DIFFERENTIATION

Insulin action in adipocytes, adipose remodeling, and systemic effects

(2021) Anna Santoro et al.   Cell Metabolism

KIM-1 mediates fatty acid uptake by renal tubular cells to promote progressive diabetic kidney disease

(2021) Yutaro Mori et al.   Cell Metabolism

Lipid metabolism and lipid signals in aging and longevity

(2021) Ayse Sena Mutlu et al.   DEVELOPMENTAL CELL

Lipid metabolism in cancer: New perspectives and emerging mechanisms

(2021) Lindsay A. Broadfield et al.   DEVELOPMENTAL CELL

Effects of in vivo phlorizin treatment and in vitro addition of carnitine, propionate, acetate, and 5-tetradecyloxy-2-furoic acid on palmitate metabolism in ovine hepatocytes

(2021) C.J. Ottemann Abbamonte et al.   JOURNAL OF DAIRY SCIENCE

Peroxidation of n-3 and n-6 polyunsaturated fatty acids in the acidic tumor environment leads to ferroptosis-mediated anticancer effects

(2021) Emeline Dierge et al.   Cell Metabolism

Altering Sphingolipid Metabolism Attenuates Cell Death and Inflammatory Response after Myocardial Infarction

(2020) Yoav Hadas et al.   CIRCULATION

Chlamydia pneumoniae infection–induced endoplasmic reticulum stress causes fatty acid–binding protein 4 secretion in murine adipocytes

(2020) Nirwana Fitriani Walenna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stearoyl-CoA desaturase-1 impairs the reparative properties of macrophages and microglia in the brain

(2020) Jeroen F.J. Bogie et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors

(2020) Haiping Wang et al.   NATURE IMMUNOLOGY

Classic and targeted anti‐leukaemic agents interfere with the cholesterol biogenesis metagene in acute myeloid leukaemia: Therapeutic implications

(2020) Fangli Chen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Acetyl-CoA Derived from Hepatic Peroxisomal β-Oxidation Inhibits Autophagy and Promotes Steatosis via mTORC1 Activation

(2020) Anyuan He et al.   MOLECULAR CELL

Functional diversity in a lipidome

(2020) Padinjat Raghu   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting DGAT1 Ameliorates Glioblastoma by Increasing Fat Catabolism and Oxidative Stress

(2020) Xiang Cheng et al.   Cell Metabolism

PHD3 Loss Promotes Exercise Capacity and Fat Oxidation in Skeletal Muscle

(2020) Haejin Yoon et al.   Cell Metabolism

Targeting Metabolism to Improve the Tumor Microenvironment for Cancer Immunotherapy

(2020) Jackie E. Bader et al.   MOLECULAR CELL

Spectroscopic coherent Raman imaging of Caenorhabditis elegans reveals lipid particle diversity

(2020) Wei-Wen Chen et al.   Nature Chemical Biology

IL-10 attenuates OxPCs-mediated lipid metabolic responses in ischemia reperfusion injury

(2020) Ashim K. Bagchi et al.   Scientific Reports

Resolving the Complexity of Spatial Lipidomics Using MALDI TIMS Imaging Mass Spectrometry

(2020) Katerina V. Djambazova et al.   ANALYTICAL CHEMISTRY

Elevation of JAML Promotes Diabetic Kidney Disease by Modulating Podocyte Lipid Metabolism

(2020) Yi Fu et al.   Cell Metabolism

Polyunsaturated fatty acid biosynthesis pathway determines ferroptosis sensitivity in gastric cancer

(2020) Ji-Yoon Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Biosynthesis of Enzymatically Oxidized Lipids

(2020) Ali A. Hajeyah et al.   Frontiers in Endocrinology

Ferroptosis as a target for protection against cardiomyopathy

(2019) Xuexian Fang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity

(2019) Kim Vriens et al.   NATURE

CHP1 Regulates Compartmentalized Glycerolipid Synthesis by Activating GPAT4

(2019) Xiphias Ge Zhu et al.   MOLECULAR CELL

Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids

(2019) Manuele Piccolis et al.   MOLECULAR CELL

Glycogen Synthase Kinase-3α Promotes Fatty Acid Uptake and Lipotoxic Cardiomyopathy

(2019) Michinari Nakamura et al.   Cell Metabolism

Genetics of Common, Complex Coronary Artery Disease

(2019) Kiran Musunuru et al.   CELL

Neuron-Astrocyte Metabolic Coupling Protects against Activity-Induced Fatty Acid Toxicity

(2019) Maria S. Ioannou et al.   CELL

Metformin promotes mitophagy in mononuclear cells: a potential in vitro model for unraveling metformin's mechanism of action

(2019) Shipra Bhansali et al.   Annals of the New York Academy of Sciences

Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling

(2019) Junfeng Bi et al.   Cell Metabolism

Role of tumor and host autophagy in cancer metabolism

(2019) Laura Poillet-Perez et al.   GENES & DEVELOPMENT

Fatty acid-binding protein 1 increases steer fat deposition by facilitating the synthesis and secretion of triacylglycerol in liver

(2019) Yujuan Wang et al.   PLoS One

Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP ‐1

(2019) Yang Zhang et al.   EMBO REPORTS

GS-0976 (Firsocostat): an investigational liver-directed acetyl-CoA carboxylase (ACC) inhibitor for the treatment of non-alcoholic steatohepatitis (NASH)

(2019) Naim Alkhouri et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Omega Fatty Acids and Inflammatory Bowel Diseases: An Overview

(2019) Ledyane Taynara Marton et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

PAHSAs enhance hepatic and systemic insulin sensitivity through direct and indirect mechanisms

(2019) Peng Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

Cardiac expression of the microsomal triglyceride transport protein protects the heart function during ischemia

(2019) Martina Klevstig et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Reduced lysosomal acid lipase activity: A new marker of liver disease severity across the clinical continuum of non-alcoholic fatty liver disease?

(2019) Baratta Francesco et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Monitoring the Sphingolipid de novo Synthesis by Stable-Isotope Labeling and Liquid Chromatography-Mass Spectrometry

(2019) Dominik Wigger et al.   Frontiers in Cell and Developmental Biology

A Compendium of Genetic Modifiers of Mitochondrial Dysfunction Reveals Intra-organelle Buffering

(2019) Tsz-Leung To et al.   CELL

Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals EPDR1 as a Novel Batokine

(2019) Atul S. Deshmukh et al.   Cell Metabolism

Thiazolidinediones: the Forgotten Diabetes Medications

(2019) Harold E. Lebovitz   Current Diabetes Reports

A fatty acid-binding protein of Streptococcus pneumoniae facilitates the acquisition of host polyunsaturated fatty acids

(2019) Jessica M. Gullett et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recent Insights Into Mechanisms of β-Cell Lipo- and Glucolipotoxicity in Type 2 Diabetes

(2019) Maria Lytrivi et al.   JOURNAL OF MOLECULAR BIOLOGY

FSP1 is a glutathione-independent ferroptosis suppressor

(2019) Sebastian Doll et al.   NATURE

The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis

(2019) Kirill Bersuker et al.   NATURE

Multiplexed and single cell tracing of lipid metabolism

(2019) Christoph Thiele et al.   NATURE METHODS

Role of acyl-CoA synthetase ACSL4 in arachidonic acid metabolism

(2019) Hiroshi Kuwata et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Dietary lipids, gut microbiota and lipid metabolism

(2019) Marc Schoeler et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Quantitative proteomic analyses reveal that GPX4 downregulation during myocardial infarction contributes to ferroptosis in cardiomyocytes

(2019) Tae-Jun Park et al.   Cell Death & Disease

Reprogramming of fatty acid metabolism in cancer

(2019) Nikos Koundouros et al.   BRITISH JOURNAL OF CANCER

FABP5 coordinates lipid signaling that promotes prostate cancer metastasis

(2019) Gregory Carbonetti et al.   Scientific Reports

Lipid accumulation and oxidation in glioblastoma multiforme

(2019) Bouchra Taïb et al.   Scientific Reports

Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis

(2018) Ismail Syed et al.   Cell Metabolism

Orlistat as a FASN inhibitor and multitargeted agent for cancer therapy

(2018) Alejandro Schcolnik-Cabrera et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Identifying key membrane protein lipid interactions using mass spectrometry

(2018) Kallol Gupta et al.   Nature Protocols

Understanding the diversity of membrane lipid composition

(2018) Takeshi Harayama et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hexane-Isopropanolic Extract of Tungrymbai, a North-East Indian fermented soybean food prevents hepatic steatosis via regulating AMPK-mediated SREBP/FAS/ACC/HMGCR and PPARα/CPT1A/UCP2 pathways

(2018) Anjum Dihingia et al.   Scientific Reports

The gut microbiota promotes hepatic fatty acid desaturation and elongation in mice

(2018) Alida Kindt et al.   Nature Communications

The glycerophosphocholine acyltransferase Gpc1 is part of a phosphatidylcholine (PC)-remodeling pathway that alters PC species in yeast

(2018) Sanket Anaokar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Various Roles of Fatty Acids

(2018) Carla de Carvalho et al.   MOLECULES

Dynamics and functions of lipid droplets

(2018) James A. Olzmann et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Increased triacylglycerol - Fatty acid substrate cycling in human skeletal muscle cells exposed to eicosapentaenoic acid

(2018) Nils G. Løvsletten et al.   PLoS One

Resolvins suppress tumor growth and enhance cancer therapy

(2017) Megan L. Sulciner et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mono-unsaturated fatty acids link H3K4me3 modifiers to C. elegans lifespan

(2017) Shuo Han et al.   NATURE

HIF drives lipid deposition and cancer in ccRCC via repression of fatty acid metabolism

(2017) Weinan Du et al.   Nature Communications

Multi-level suppression of receptor-PI3K-mTORC1 by fatty acid synthase inhibitors is crucial for their efficacy against ovarian cancer cells

(2017) Renate Wagner et al.   Oncotarget

Modulating the metabolism by trimetazidine enhances myoblast differentiation and promotes myogenesis in cachectic tumor-bearing c26 mice

(2017) Lucia Gatta et al.   Oncotarget

Adipose KLF15 Controls Lipid Handling to Adapt to Nutrient Availability

(2017) Keiichiro Matoba et al.   Cell Reports

Lipid Biomarkers for Risk Assessment in Acute Coronary Syndromes

(2017) Jeffrey W. Meeusen et al.   Current Cardiology Reports

Silencing of FABP1 ameliorates hepatic steatosis, inflammation, and oxidative stress in mice with nonalcoholic fatty liver disease

(2017) Takako Mukai et al.   FEBS Open Bio

Fatty acid metabolism by the osteoblast

(2017) Priyanka Kushwaha et al.   BONE

Surprises From Genetic Analyses of Lipid Risk Factors for Atherosclerosis

(2016) Kiran Musunuru et al.   CIRCULATION RESEARCH

Preclinical Evaluation of Fatty Acid Synthase and EGFR Inhibition in Triple-Negative Breast Cancer

(2016) A. Giro-Perafita et al.   CLINICAL CANCER RESEARCH

Loss of Junctional Adhesion Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat, Fructose, and Cholesterol

(2016) Khalidur Rahman et al.   GASTROENTEROLOGY

Diacylglycerol acyltransferase 2 links glucose utilization to fatty acid oxidation in the brown adipocytes

(2016) Zehra Irshad et al.   JOURNAL OF LIPID RESEARCH

PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2

(2016) Natalie J. German et al.   MOLECULAR CELL

Lipidomics Analyses Reveal Temporal and Spatial Lipid Organization and Uncover Daily Oscillations in Intracellular Organelles

(2016) Rona Aviram et al.   MOLECULAR CELL

Targeting metastasis-initiating cells through the fatty acid receptor CD36

(2016) Gloria Pascual et al.   NATURE

Lipidomics for studying metabolism

(2016) Xianlin Han   Nature Reviews Endocrinology

Obesity-related glomerulopathy: clinical and pathologic characteristics and pathogenesis

(2016) Vivette D. D'Agati et al.   Nature Reviews Nephrology

Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia

(2016) Xue Gao et al.   Nature Communications

Lipids Reprogram Metabolism to Become a Major Carbon Source for Histone Acetylation

(2016) Eoin McDonnell et al.   Cell Reports

Lipid metabolic reprogramming in cancer cells

(2016) S Beloribi-Djefaflia et al.   Oncogenesis

Mammalian lipoxygenases and their biological relevance

(2015) Hartmut Kuhn et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Mitochondrial dysfunction in fatty acid oxidation disorders: insights from human and animal studies

(2015) M. Wajner et al.   BIOSCIENCE REPORTS

An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis

(2015) Kıvanç Birsoy et al.   CELL

Antioxidant Role for Lipid Droplets in a Stem Cell Niche of Drosophila

(2015) Andrew P. Bailey et al.   CELL

A Global Map of Lipid-Binding Proteins and Their Ligandability in Cells

(2015) Micah J. Niphakis et al.   CELL

The c-Met Tyrosine Kinase Inhibitor JNJ-38877605 Causes Renal Toxicity through Species-Specific Insoluble Metabolite Formation

(2015) M. P. Lolkema et al.   CLINICAL CANCER RESEARCH

SREBP maintains lipid biosynthesis and viability of cancer cells under lipid- and oxygen-deprived conditions and defines a gene signature associated with poor survival in glioblastoma multiforme

(2015) C A Lewis et al.   ONCOGENE

AMP-Activated Protein Kinase Interacts with the Peroxisome Proliferator-Activated Receptor Delta to Induce Genes Affecting Fatty Acid Oxidation in Human Macrophages

(2015) Marina Kemmerer et al.   PLoS One

HIF2 -Dependent Lipid Storage Promotes Endoplasmic Reticulum Homeostasis in Clear-Cell Renal Cell Carcinoma

(2015) B. Qiu et al.   Cancer Discovery

Fatty acid remodeling by LPCAT3 enriches arachidonate in phospholipid membranes and regulates triglyceride transport

(2015) Tomomi Hashidate-Yoshida et al.   eLife

The mitochondrial citrate transporter, CIC, is essential for mitochondrial homeostasis.

(2015) Olga Catalina-Rodriguez et al.   Oncotarget

Akt-Dependent Metabolic Reprogramming Regulates Tumor Cell Histone Acetylation

(2014) Joyce V. Lee et al.   Cell Metabolism

Lipotoxicity in the Pancreatic Beta Cell: Not Just Survival and Function, but Proliferation as Well?

(2014) Rohit B. Sharma et al.   Current Diabetes Reports

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

(2014) Jose Pedro Friedmann Angeli et al.   NATURE CELL BIOLOGY

Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages

(2014) Stanley Ching-Cheng Huang et al.   NATURE IMMUNOLOGY

Important role of ventromedial hypothalamic carnitine palmitoyltransferase-1a in the control of food intake

(2013) Su Gao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

MAM (mitochondria-associated membranes) in mammalian cells: Lipids and beyond

(2013) Jean E. Vance   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

An Essential Requirement for the SCAP/SREBP Signaling Axis to Protect Cancer Cells from Lipotoxicity

(2013) K. J. Williams et al.   CANCER RESEARCH

Cellular Fatty Acid Metabolism and Cancer

(2013) Erin Currie et al.   Cell Metabolism

Stearoyl-CoA Desaturase 1 Is a Novel Molecular Therapeutic Target for Clear Cell Renal Cell Carcinoma

(2013) C. A. von Roemeling et al.   CLINICAL CANCER RESEARCH

Physiological Role of Acyl Coenzyme A Synthetase Homologs in Lipid Metabolism in Neurospora crassa

(2013) Christine M. Roche et al.   EUKARYOTIC CELL

Yeast Phospholipase C Is Required for Normal Acetyl-CoA Homeostasis and Global Histone Acetylation

(2013) Luciano Galdieri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endoplasmic Reticulum (ER) Stress and Hypoxia Response Pathways Interact to Potentiate Hypoxia-inducible Factor 1 (HIF-1) Transcriptional Activity on Targets Like Vascular Endothelial Growth Factor (VEGF)

(2013) Ethel R. Pereira et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Why does Brain Metabolism not Favor Burning of Fatty Acids to Provide Energy? - Reflections on Disadvantages of the Use of Free Fatty Acids as Fuel for Brain

(2013) Peter Schönfeld et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Imaging of neutral lipids by oil red O for analyzing the metabolic status in health and disease

(2013) Annika Mehlem et al.   Nature Protocols

Cerulenin Blockade of Fatty Acid Synthase Reverses Hepatic Steatosis in ob/ob Mice

(2013) Gang Cheng et al.   PLoS One

Towards metabolic biomarkers of insulin resistance and type 2 diabetes: progress from the metabolome

(2013) Lee D Roberts et al.   Lancet Diabetes & Endocrinology

Identification, optimisation and in vivo evaluation of oxadiazole DGAT-1 inhibitors for the treatment of obesity and diabetes

(2012) William McCoull et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

ATP-Citrate Lyase: A Key Player in Cancer Metabolism

(2012) N. Zaidi et al.   CANCER RESEARCH

Lipid Metabolism and Toxicity in the Heart

(2012) Ira J. Goldberg et al.   Cell Metabolism

Investigating Metformin for Cancer Prevention and Treatment: The End of the Beginning

(2012) Michael N. Pollak   Cancer Discovery

Functional Metabolic Screen Identifies 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 4 as an Important Regulator of Prostate Cancer Cell Survival

(2012) Susana Ros et al.   Cancer Discovery

Fatty acid transport proteins, implications in physiology and disease

(2011) Melissa Kazantzis et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Small Nucleolar RNAs U32a, U33, and U35a Are Critical Mediators of Metabolic Stress

(2011) Carlos I. Michel et al.   Cell Metabolism

Development of a Liver-Targeted Stearoyl-CoA Desaturase (SCD) Inhibitor (MK-8245) to Establish a Therapeutic Window for the Treatment of Diabetes and Dyslipidemia

(2011) Renata M. Oballa et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Evaluation of Diarylthiazole Derivatives That Inhibit Activation of Sterol Regulatory Element-Binding Proteins

(2011) Shinji Kamisuki et al.   JOURNAL OF MEDICINAL CHEMISTRY

Multi-dimensional mass spectrometry-based shotgun lipidomics and novel strategies for lipidomic analyses

(2011) Xianlin Han et al.   MASS SPECTROMETRY REVIEWS

The immune system in atherosclerosis

(2011) Göran K Hansson et al.   NATURE IMMUNOLOGY

AICAR inhibits cancer cell growth and triggers cell-type distinct effects on OXPHOS biogenesis, oxidative stress and Akt activation

(2010) Caroline Jose et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells

(2010) Lisa S. Pike et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

De novo Lipogenesis Protects Cancer Cells from Free Radicals and Chemotherapeutics by Promoting Membrane Lipid Saturation

(2010) E. Rysman et al.   CANCER RESEARCH

Renal lipid metabolism and lipotoxicity

(2010) Ion Alexandru Bobulescu   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Ceramide and ceramide 1-phosphate in health and disease

(2010) Lide Arana et al.   Lipids in Health and Disease

Abrogation of De novo Lipogenesis by Stearoyl-CoA Desaturase 1 Inhibition Interferes with Oncogenic Signaling and Blocks Prostate Cancer Progression in Mice

(2010) V. Fritz et al.   MOLECULAR CANCER THERAPEUTICS

Fatty acid transport across the cell membrane: Regulation by fatty acid transporters

(2010) Robert W. Schwenk et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Biochemistry, physiology, and genetics of GPAT, AGPAT, and lipin enzymes in triglyceride synthesis

(2009) Kazuharu Takeuchi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Automated Lipid Identification and Quantification by Multidimensional Mass Spectrometry-Based Shotgun Lipidomics

(2009) Kui Yang et al.   ANALYTICAL CHEMISTRY

Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction

(2009) Ismael Samudio et al.   JOURNAL OF CLINICAL INVESTIGATION

Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment

(2009) Zachary T. Schafer et al.   NATURE

Malonyl-CoA decarboxylase inhibition is selectively cytotoxic to human breast cancer cells

(2009) W Zhou et al.   ONCOGENE

The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis

(2009) D. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation

(2009) K. E. Wellen et al.   SCIENCE

Cellular fatty acid uptake: a pathway under construction

(2009) Xiong Su et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

ATP Citrate Lyase: Activation and Therapeutic Implications in Non-Small Cell Lung Cancer

(2008) T. Migita et al.   CANCER RESEARCH

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

(2008) Timothy R. Koves et al.   Cell Metabolism

Obesity and Free Fatty Acids

(2008) Guenther Boden   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Variants in the CD36 gene associate with the metabolic syndrome and high-density lipoprotein cholesterol

(2008) Latisha Love-Gregory et al.   HUMAN MOLECULAR GENETICS

The role of oxidized phospholipids in atherosclerosis: Fig. 1.

(2008) Judith A. Berliner et al.   JOURNAL OF LIPID RESEARCH

Membrane phospholipid synthesis and endoplasmic reticulum function

(2008) Paolo Fagone et al.   JOURNAL OF LIPID RESEARCH

Validation of Diacyl Glycerolacyltransferase I as a Novel Target for the Treatment of Obesity and Dyslipidemia Using a Potent and Selective Small Molecule Inhibitor

(2008) Gang Zhao et al.   JOURNAL OF MEDICINAL CHEMISTRY