Polyunsaturated fatty acid biosynthesis pathway determines ferroptosis sensitivity in gastric cancer
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Polyunsaturated fatty acid biosynthesis pathway determines ferroptosis sensitivity in gastric cancer
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 117, Issue 51, Pages 32433-32442
Publisher
Proceedings of the National Academy of Sciences
Online
2020-12-08
DOI
10.1073/pnas.2006828117
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Ferroptosis: past, present and future
- (2020) Jie Li et al. Cell Death & Disease
- Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer
- (2019) Matthew J. Watt et al. Science Translational Medicine
- Ferroptosis as a target for protection against cardiomyopathy
- (2019) Xuexian Fang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting Ferroptosis to Iron Out Cancer
- (2019) Behrouz Hassannia et al. CANCER CELL
- Fatty acid transport protein 2 reprograms neutrophils in cancer
- (2019) Filippo Veglia et al. NATURE
- Steroyl-CoA Desaturase 1 (SCD1) protects ovarian cancer cells from ferroptotic cell death
- (2019) Lia Tesfay et al. CANCER RESEARCH
- Impact of 17β-HSD12, the 3-ketoacyl-CoA reductase of long-chain fatty acid synthesis, on breast cancer cell proliferation and migration
- (2019) Maria Tsachaki et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Structural basis for recognition of the tumor suppressor protein PTPN14 by the oncoprotein E7 of human papillomavirus
- (2019) Hye-Yeoung Yun et al. PLOS BIOLOGY
- Publisher Correction: Intercellular interaction dictates cancer cell ferroptosis via NF2–YAP signalling
- (2019) Jiao Wu et al. NATURE
- Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation
- (2019) Jiajun Zhu et al. Cell Metabolism
- Ferroptosis is controlled by the coordinated transcriptional regulation of glutathione and labile iron metabolism by the transcription factor BACH1
- (2019) Hironari Nishizawa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The chemical basis of ferroptosis
- (2019) Marcus Conrad et al. Nature Chemical Biology
- Quantitative proteomic analyses reveal that GPX4 downregulation during myocardial infarction contributes to ferroptosis in cardiomyocytes
- (2019) Tae-Jun Park et al. Cell Death & Disease
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
- (2018) Lorenzo Galluzzi et al. CELL DEATH AND DIFFERENTIATION
- Predictive test for chemotherapy response in resectable gastric cancer: a multi-cohort, retrospective analysis
- (2018) Jae-Ho Cheong et al. LANCET ONCOLOGY
- Clinical and genomic landscape of gastric cancer with a mesenchymal phenotype
- (2018) Sang Cheul Oh et al. Nature Communications
- A pharmacological probe identifies cystathionine β-synthase as a new negative regulator for ferroptosis
- (2018) Li Wang et al. Cell Death & Disease
- Role of Mitochondria in Ferroptosis
- (2018) Minghui Gao et al. MOLECULAR CELL
- Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition
- (2017) Matthew J. Hangauer et al. NATURE
- Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
- (2017) Vasanthi S. Viswanathan et al. NATURE
- Nrf2-Keap1 pathway promotes cell proliferation and diminishes ferroptosis
- (2017) Z Fan et al. Oncogenesis
- Nrf2 inhibition reverses the resistance of cisplatin-resistant head and neck cancer cells to artesunate-induced ferroptosis
- (2017) Jong-Lyel Roh et al. Redox Biology
- Uncovering the DNA methylation landscape in key regulatory regions within the FADS cluster
- (2017) Elaheh Rahbar et al. PLoS One
- Identification of ACSL4 as a biomarker and contributor of ferroptosis
- (2016) Hua Yuan et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition
- (2016) Sebastian Doll et al. Nature Chemical Biology
- Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death
- (2015) Scott J. Dixon et al. ACS Chemical Biology
- Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation
- (2015) M Hayano et al. CELL DEATH AND DIFFERENTIATION
- Chemotherapy Resistance in Diffuse-Type Gastric Adenocarcinoma Is Mediated by RhoA Activation in Cancer Stem-Like Cells
- (2015) C. Yoon et al. CLINICAL CANCER RESEARCH
- Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells
- (2015) Xiaofang Sun et al. HEPATOLOGY
- Glutaminolysis and Transferrin Regulate Ferroptosis
- (2015) Minghui Gao et al. MOLECULAR CELL
- Regulation of Ferroptotic Cancer Cell Death by GPX4
- (2014) Wan Seok Yang et al. CELL
- Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models
- (2014) Rachid Skouta et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
- (2014) Jose Pedro Friedmann Angeli et al. NATURE CELL BIOLOGY
- Synchronized renal tubular cell death involves ferroptosis
- (2014) Andreas Linkermann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis
- (2014) Scott J Dixon et al. eLife
- Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies
- (2014) Glenn S Cowley et al. Scientific Data
- Iron-dependent cell death of hepatocellular carcinoma cells exposed to sorafenib
- (2013) Christophe Louandre et al. INTERNATIONAL JOURNAL OF CANCER
- Inferring tumour purity and stromal and immune cell admixture from expression data
- (2013) Kosuke Yoshihara et al. Nature Communications
- Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
- (2012) Scott J. Dixon et al. CELL
- The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
- (2012) Jordi Barretina et al. NATURE
- Development of small-molecule probes that selectively kill cells induced to express mutant RAS
- (2011) Michel Weïwer et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer
- (2011) H. W. Cheung et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Towards patient-based cancer therapeutics
- (2010) Stuart L Schreiber et al. NATURE BIOTECHNOLOGY
- Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death
- (2008) Alexander Seiler et al. Cell Metabolism
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started