The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis

Deconstructing feedback-signaling networks to improve anticancer therapy with mTORC1 inhibitors

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S6K1 Plays a Key Role in Glial Transformation

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Amino Acids Activate mTOR Complex 1 via Ca2+/CaM Signaling to hVps34

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The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

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Changes in Tumor Metabolism as Readout for Mammalian Target of Rapamycin Kinase Inhibition by Rapamycin in Glioblastoma

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Targeting the PI3K–AKT–mTOR pathway: progress, pitfalls, and promises

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A pilot study of everolimus and gefitinib in the treatment of recurrent glioblastoma (GBM)

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AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

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The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

(2008) Heather R. Christofk et al.   NATURE

Antitumor Activity of Rapamycin in a Phase I Trial for Patients with Recurrent PTEN-Deficient Glioblastoma

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